SI2766393T1 - Protitelesa Anti-HtrA1 in postopki uporabe - Google Patents

Protitelesa Anti-HtrA1 in postopki uporabe

Info

Publication number
SI2766393T1
SI2766393T1 SI201231378T SI201231378T SI2766393T1 SI 2766393 T1 SI2766393 T1 SI 2766393T1 SI 201231378 T SI201231378 T SI 201231378T SI 201231378 T SI201231378 T SI 201231378T SI 2766393 T1 SI2766393 T1 SI 2766393T1
Authority
SI
Slovenia
Prior art keywords
methods
htra1 antibodies
htra1
antibodies
Prior art date
Application number
SI201231378T
Other languages
English (en)
Slovenian (sl)
Inventor
Yan Wu
Lookeren-Campagne Menno Van
Daniel Kirchhofer
Michael Terry Lipari
Jr. Kenneth J. Katschke
Paul M. Moran
Scott Stawicki
Wei-Ching Liang
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of SI2766393T1 publication Critical patent/SI2766393T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
SI201231378T 2011-10-14 2012-10-12 Protitelesa Anti-HtrA1 in postopki uporabe SI2766393T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161547649P 2011-10-14 2011-10-14
PCT/US2012/059878 WO2013055998A1 (en) 2011-10-14 2012-10-12 ANTI-HtrA1 ANTIBODIES AND METHODS OF USE
EP12840084.3A EP2766393B1 (en) 2011-10-14 2012-10-12 ANTI-HtrA1 ANTIBODIES AND METHODS OF USE

Publications (1)

Publication Number Publication Date
SI2766393T1 true SI2766393T1 (sl) 2018-10-30

Family

ID=48082468

Family Applications (1)

Application Number Title Priority Date Filing Date
SI201231378T SI2766393T1 (sl) 2011-10-14 2012-10-12 Protitelesa Anti-HtrA1 in postopki uporabe

Country Status (33)

Country Link
US (3) US9738727B2 (enExample)
EP (2) EP2766393B1 (enExample)
JP (2) JP6532678B2 (enExample)
KR (2) KR102102862B1 (enExample)
CN (2) CN108373506A (enExample)
AR (1) AR088322A1 (enExample)
AU (2) AU2012322618A1 (enExample)
BR (1) BR112014008862A2 (enExample)
CA (1) CA2850032C (enExample)
CL (1) CL2014000888A1 (enExample)
CO (1) CO7020870A2 (enExample)
CR (1) CR20140212A (enExample)
DK (1) DK2766393T3 (enExample)
EA (1) EA201490778A1 (enExample)
ES (1) ES2687951T3 (enExample)
HK (1) HK1255608A1 (enExample)
HR (1) HRP20181457T1 (enExample)
HU (1) HUE039133T2 (enExample)
IL (1) IL232055B (enExample)
LT (1) LT2766393T (enExample)
MA (1) MA35712B1 (enExample)
MX (2) MX372661B (enExample)
PE (1) PE20141562A1 (enExample)
PH (1) PH12014500841B1 (enExample)
PL (1) PL2766393T3 (enExample)
PT (1) PT2766393T (enExample)
RS (1) RS57645B1 (enExample)
SG (1) SG11201401477XA (enExample)
SI (1) SI2766393T1 (enExample)
TR (1) TR201811270T4 (enExample)
TW (1) TW201321414A (enExample)
WO (1) WO2013055998A1 (enExample)
ZA (1) ZA201402172B (enExample)

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EA201692109A1 (ru) 2014-05-01 2017-03-31 Дженентек, Инк. Варианты антител к фактору d и их применение
SG11201703767XA (en) 2014-11-10 2017-06-29 Genentech Inc Anti-interleukin-33 antibodies and uses thereof
JP2018531980A (ja) 2015-10-30 2018-11-01 ジェネンテック， インコーポレイテッド 抗ｄ因子抗体製剤
US10407510B2 (en) 2015-10-30 2019-09-10 Genentech, Inc. Anti-factor D antibodies and conjugates
BR112018007703A2 (pt) * 2015-10-30 2018-11-06 Genentech Inc anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
WO2017075252A1 (en) 2015-10-30 2017-05-04 Genentech, Inc. Anti-factor d antibody variant conjugates and uses thereof
US10526315B2 (en) 2016-06-21 2020-01-07 Orion Ophthalmology LLC Carbocyclic prolinamide derivatives
AU2017282651B2 (en) 2016-06-21 2021-08-12 Orion Ophthalmology LLC Heterocyclic prolinamide derivatives
JP2018096930A (ja) * 2016-12-16 2018-06-21 公益財団法人ヒューマンサイエンス振興財団 加齢黄斑変性の診断マーカー、診断キット、診断補助方法、及び、発症リスク判定方法
WO2018117244A1 (ja) * 2016-12-22 2018-06-28 第一三共株式会社 加齢黄斑変性症治療用ペプチド
US20200103419A1 (en) 2017-03-27 2020-04-02 The Schepens Eye Research Institute, Inc. Blood biomarkers and diagnostic methods for small vessel diseases
US11453718B2 (en) 2017-03-27 2022-09-27 The Schepens Eye Research Institute, Inc. NOTCH3 agonist compositions and methods for treating small vessel diseases
JP2021507253A (ja) * 2017-12-21 2021-02-22 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｈｔｒａ１ ｒｎａアンタゴニストについてのコンパニオン診断
JP7303189B2 (ja) * 2018-06-21 2023-07-04 第一三共株式会社 網膜色素変性症治療用ペプチド
TW202039585A (zh) * 2018-11-16 2020-11-01 美商雙子治療公司 靶向htra1之基於抗體之療法及使用方法
WO2020109343A1 (en) 2018-11-29 2020-06-04 F. Hoffmann-La Roche Ag Combination therapy for treatment of macular degeneration
CN113874395A (zh) * 2018-12-24 2021-12-31 威特拉公司 鉴定表位和互补位的方法
JP2022526429A (ja) 2019-04-10 2022-05-24 ザ ユニバーシティ オブ ユタ リサーチ ファウンデイション Ａｍｄの処置のためのｈｔｒａ１調節
EP4118114A1 (en) 2020-03-13 2023-01-18 Genentech, Inc. Anti-interleukin-33 antibodies and uses thereof
AU2021320658A1 (en) * 2020-08-04 2023-03-02 Exelixis, Inc. CD47 binding agents and uses thereof
WO2022170166A1 (en) * 2021-02-08 2022-08-11 Ngm Biopharmaceuticals, Inc. Htra1-binding agents and methods of use thereof

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