SI2696889T1 - Variants of human GDNF - Google Patents
Variants of human GDNF Download PDFInfo
- Publication number
- SI2696889T1 SI2696889T1 SI201231134T SI201231134T SI2696889T1 SI 2696889 T1 SI2696889 T1 SI 2696889T1 SI 201231134 T SI201231134 T SI 201231134T SI 201231134 T SI201231134 T SI 201231134T SI 2696889 T1 SI2696889 T1 SI 2696889T1
- Authority
- SI
- Slovenia
- Prior art keywords
- seq
- variant
- human gdnf
- human
- rcgci
- Prior art date
Links
- 101150082979 gdnf gene Proteins 0.000 title 1
- 101000997829 Homo sapiens Glial cell line-derived neurotrophic factor Proteins 0.000 claims abstract 9
- 102000052654 human GDNF Human genes 0.000 claims abstract 9
- 102000034615 Glial cell line-derived neurotrophic factor Human genes 0.000 claims abstract 3
- 108091010837 Glial cell line-derived neurotrophic factor Proteins 0.000 claims abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 208000018737 Parkinson disease Diseases 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 239000000969 carrier Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Psychology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161474024P | 2011-04-11 | 2011-04-11 | |
| PCT/US2012/031927 WO2012141936A1 (en) | 2011-04-11 | 2012-04-03 | Variants of human gdnf |
| EP12712874.2A EP2696889B1 (en) | 2011-04-11 | 2012-04-03 | Variants of human gdnf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2696889T1 true SI2696889T1 (en) | 2018-01-31 |
Family
ID=45932578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI201231134T SI2696889T1 (en) | 2011-04-11 | 2012-04-03 | Variants of human GDNF |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US9243046B2 (enExample) |
| EP (1) | EP2696889B1 (enExample) |
| JP (1) | JP6093345B2 (enExample) |
| KR (1) | KR101554799B1 (enExample) |
| CN (1) | CN103635201B (enExample) |
| AU (1) | AU2012243178B2 (enExample) |
| BR (1) | BR112013026004B1 (enExample) |
| CA (1) | CA2833158C (enExample) |
| CY (1) | CY1119750T1 (enExample) |
| DK (1) | DK2696889T3 (enExample) |
| EA (1) | EA025129B1 (enExample) |
| ES (1) | ES2656020T3 (enExample) |
| HR (1) | HRP20171993T1 (enExample) |
| HU (1) | HUE036239T2 (enExample) |
| IL (1) | IL228102A (enExample) |
| LT (1) | LT2696889T (enExample) |
| ME (1) | ME02849B (enExample) |
| MX (1) | MX337206B (enExample) |
| NO (1) | NO2696889T3 (enExample) |
| PL (1) | PL2696889T3 (enExample) |
| PT (1) | PT2696889T (enExample) |
| RS (1) | RS56639B1 (enExample) |
| SG (1) | SG193483A1 (enExample) |
| SI (1) | SI2696889T1 (enExample) |
| TW (1) | TWI583698B (enExample) |
| UA (1) | UA112981C2 (enExample) |
| WO (1) | WO2012141936A1 (enExample) |
| ZA (1) | ZA201306556B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3454886A1 (en) | 2016-05-13 | 2019-03-20 | Instituto de Medicina Molecular | Methods of treating diseases associated with ilc3 cells |
| US20230022970A1 (en) * | 2019-12-19 | 2023-01-26 | Transfert Plus, Société En Commandite | Use of glial cell line-derived neurotrophic factor (gdnf) for the treatment of enteric neuropathies |
| EP4347645A1 (en) | 2021-06-03 | 2024-04-10 | Fundação D. Anna de Sommer Champalimaud e Dr. Carlos Montez Champalimaud Foundation | Neuro-mesenchyme units control ilc2 and obesity via a brain-adipose circuit |
| CN116606365A (zh) * | 2023-02-24 | 2023-08-18 | 肇庆医学高等专科学校 | 一种gdnf新型变体及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993006116A1 (en) | 1991-09-20 | 1993-04-01 | Syntex-Synergen Neuroscience Joint Venture | Glial derived neurotrophic factor |
| US6184200B1 (en) * | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
| US6042579A (en) | 1997-04-30 | 2000-03-28 | Medtronic, Inc. | Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain |
| DE19816186A1 (de) | 1998-04-14 | 1999-10-21 | Univ Muenchen L Maximilians | GDNF-kodierende DNA, Teile davon und GDNF-Varianten |
| US8946151B2 (en) | 2003-02-24 | 2015-02-03 | Northern Bristol N.H.S. Trust Frenchay Hospital | Method of treating Parkinson's disease in humans by convection-enhanced infusion of glial cell-line derived neurotrophic factor to the putamen |
| FI20070808A0 (fi) | 2007-10-25 | 2007-10-25 | Mart Saarma | GDNF:n silmukointivariantit ja niiden käytöt |
| CN101775072B (zh) * | 2008-05-21 | 2012-09-05 | 王尚武 | 一种融合穿透肽的神经细胞营养因子gdnf |
| WO2010090523A1 (en) * | 2009-02-06 | 2010-08-12 | Pepscan Systems B.V. | Truncated cystine-knot proteins |
-
2012
- 2012-03-04 UA UAA201311714A patent/UA112981C2/uk unknown
- 2012-03-27 TW TW101110653A patent/TWI583698B/zh active
- 2012-04-03 ES ES12712874.2T patent/ES2656020T3/es active Active
- 2012-04-03 EA EA201370204A patent/EA025129B1/ru not_active IP Right Cessation
- 2012-04-03 PT PT127128742T patent/PT2696889T/pt unknown
- 2012-04-03 US US14/000,704 patent/US9243046B2/en active Active
- 2012-04-03 NO NO12712874A patent/NO2696889T3/no unknown
- 2012-04-03 WO PCT/US2012/031927 patent/WO2012141936A1/en not_active Ceased
- 2012-04-03 BR BR112013026004-1A patent/BR112013026004B1/pt not_active IP Right Cessation
- 2012-04-03 KR KR1020137026366A patent/KR101554799B1/ko not_active Expired - Fee Related
- 2012-04-03 CA CA2833158A patent/CA2833158C/en not_active Expired - Fee Related
- 2012-04-03 SI SI201231134T patent/SI2696889T1/en unknown
- 2012-04-03 HU HUE12712874A patent/HUE036239T2/hu unknown
- 2012-04-03 MX MX2013011919A patent/MX337206B/es active IP Right Grant
- 2012-04-03 LT LTEP12712874.2T patent/LT2696889T/lt unknown
- 2012-04-03 AU AU2012243178A patent/AU2012243178B2/en not_active Ceased
- 2012-04-03 DK DK12712874.2T patent/DK2696889T3/en active
- 2012-04-03 CN CN201280018010.7A patent/CN103635201B/zh active Active
- 2012-04-03 PL PL12712874T patent/PL2696889T3/pl unknown
- 2012-04-03 HR HRP20171993TT patent/HRP20171993T1/hr unknown
- 2012-04-03 ME MEP-2017-276A patent/ME02849B/me unknown
- 2012-04-03 RS RS20171274A patent/RS56639B1/sr unknown
- 2012-04-03 JP JP2014505179A patent/JP6093345B2/ja active Active
- 2012-04-03 SG SG2013069554A patent/SG193483A1/en unknown
- 2012-04-03 EP EP12712874.2A patent/EP2696889B1/en active Active
-
2013
- 2013-08-22 IL IL228102A patent/IL228102A/en active IP Right Grant
- 2013-08-30 ZA ZA2013/06556A patent/ZA201306556B/en unknown
-
2018
- 2018-01-09 CY CY20181100021T patent/CY1119750T1/el unknown
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