SI2453922T1 - Antibakterijski oralni sestavek - Google Patents

Antibakterijski oralni sestavek Download PDF

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SI2453922T1
SI2453922T1 SI201031602T SI201031602T SI2453922T1 SI 2453922 T1 SI2453922 T1 SI 2453922T1 SI 201031602 T SI201031602 T SI 201031602T SI 201031602 T SI201031602 T SI 201031602T SI 2453922 T1 SI2453922 T1 SI 2453922T1
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use according
oral
acid
red
composition
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SI201031602T
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Remigio Piergallini
Nikolaos Loupis
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Klox Technologies Inc.
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Publication of SI2453922T1 publication Critical patent/SI2453922T1/sl

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    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
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Claims (15)

  1. ANTIBAKTERIJSKI ORALNI SESTAVEK PATENTNI ZAHTEVKI
    1. Uporaba fotoaktivabilnega sestavka za izdelavo zdravila za zdravljenje oralne bolezni, kjer omenjeni sestavek obsega: vsaj en oksidant, vsaj en fotoaktivator, ki je sposoben aktivirati oksidant; in vsaj en dejavnik zdravljenja, izbran izmed hialuronske kisline, glukozamina in alantoina, skupaj s farmakološko sprejemljivim nosilcem in omenjeno zdravljenje obsega: a) nanašanje omenjene sestave na usta pacienta; in b) zdravljenje omenjenih ustih koraka a) z aktinično svetlobe v času, ki zadostuje, da omenjeni fotoaktivator povzroči aktivacijo omenjenega oksidanta.
  2. 2. Uporaba po zahtevku 1, kjer je omenjena oralna bolezen izbrana izmed gingivitisa, periodontitisa, periodontalne bolezni, oralne kandidiaze, lichen planus, stomatitisa, lezije herpes simpleksa, oralnega mukozitisa, oralnih ulkusov, oralne submukuzne fibroze in glositisa.
  3. 3. Uporaba po zahtevku 2, kjer je oralna bolezen periodontitis.
  4. 4. Uporaba po katerem koli od zahtevkov 1 do 3, kjer je oksidant izbran izmed vodikovega peroksida, karbamid peroksida, benzoil peroksida, peroksi kisline in perkarbonata alkalijske kovine.
  5. 5. Uporaba po katerem koli od zahtevkov 1 do 4, kjer sestavek nadalje obsega vsaj eno hidrofilno želimo sredstvo, kot je glukoza, modificiran škrob, metil celuloza, karboksimetil celuloza, propil celuloza, hidroksipropil celuloza, polimeri karbopol®, alginska kislina, natrijev alginat, kalijev alginat, amonijev alginat, kalcij alginat, agar, karagenan, gumi iz rožičevca, pektin in želatina.
  6. 6. Uporaba po katerem koli od zahtevkov 1 do 5, kjer je fotoaktivator izbran izmed barvila derivata ksantena, azo barvila, biološkega madeža in karotenoida.
  7. 7. Uporaba po zahtevku 6, kjer je navedeno barvilo derivata ksantena izbrano izmed fluor barvila, fluoron barvila, in rodol barvila (ang. rhodole dye).
  8. 8. Uporaba po zahtevku 7, kjer je omenjeno fluorensko barvilo izbrano izmed pironin barvila, kot sta pironin Y in pironin B in rodamin barvila, kot so rodamin B, rodamin G in rodamin WT.
  9. 9. Uporaba po zahtevku 7, kjer je omenjeno fluoron barvilo izbrano izmed fluorescina in fluorescinskih derivatov.
  10. 10. Uporaba po zahtevku 9, kjer je navedeni fluorescinski derivat izbran izmed floksina B, rose bengal, merbromina, eozin Y, eozin B in eritrozin B.
  11. 11. Uporaba po zahtevku 10, kjer je omenjeni derivat fluorescina Eozin Y.
  12. 12. Uporaba po zahtevku 6, kjer je omenjeno azo barvilo izbrano izmed metil vijoličnega, nevtralnega rdečega, para rdečega, amaranta, karmoizina, alura rdeče AC, tartrazina, oranžno G, rdeče 4R, metil rdečega in mureksid-amonijevega purpurata.
  13. 13. Uporaba po zahtevku 6, kjer je omenjeni biološki madež izbran izmed safranina O, bazičnega fuksina, kislega fuksina, 3,3'-diheksilokarbocianin jodida, karminske kisline in indocianin zelenega.
  14. 14. Uporaba po zahtevku 6, kjer je navedeni karotenoid izbran izmed krocetina, a-krocina (S,S-diapo-S, S-karotenojske kisline), zeaksantina, likopena, a-karotena, β-karotena, biksina in fukoksantina, ali kjer je navedeni karotenoid pristen v sestavku kot zmes, izbrana iz rdečega prahu iz žafrana, ekstrakta annatto in ekstrakta rjave alge.
  15. 15. Uporaba po katerem koli od zahtevkov 1-14, kjer omenjeni sestavek nadalje obsega vsaj eno kelatno sredstvo, izbrano iz etilendiamintetraocetne kisline (EDTA) in etilenglikol tetraocetne kisline (EGTA).
SI201031602T 2009-07-17 2010-07-19 Antibakterijski oralni sestavek SI2453922T1 (sl)

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US22635409P 2009-07-17 2009-07-17
EP10799337.0A EP2453922B1 (en) 2009-07-17 2010-07-19 Antibacterial oral composition
PCT/CA2010/001134 WO2011006263A1 (en) 2009-07-17 2010-07-19 Antibacterial oral composition

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AU (1) AU2010273144B2 (sl)
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IL (2) IL217540A (sl)
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SI (1) SI2453922T1 (sl)
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JP2016511672A (ja) 2013-03-01 2016-04-21 クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． 光線療法装置、方法および使用

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