US4057685A
(en)
|
1972-02-02 |
1977-11-08 |
Abbott Laboratories |
Chemically modified endotoxin immunizing agent
|
GB2073015B
(en)
|
1980-02-19 |
1984-07-11 |
Rondel Ltd |
Mattress
|
US4673574A
(en)
|
1981-08-31 |
1987-06-16 |
Anderson Porter W |
Immunogenic conjugates
|
US4459286A
(en)
|
1983-01-31 |
1984-07-10 |
Merck & Co., Inc. |
Coupled H. influenzae type B vaccine
|
US4663160A
(en)
|
1983-03-14 |
1987-05-05 |
Miles Laboratories, Inc. |
Vaccines for gram-negative bacteria
|
US4761283A
(en)
|
1983-07-05 |
1988-08-02 |
The University Of Rochester |
Immunogenic conjugates
|
US4808700A
(en)
|
1984-07-09 |
1989-02-28 |
Praxis Biologics, Inc. |
Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
|
IT1187753B
(it)
|
1985-07-05 |
1987-12-23 |
Sclavo Spa |
Coniugati glicoproteici ad attivita' immunogenica trivalente
|
US5204098A
(en)
|
1988-02-16 |
1993-04-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polysaccharide-protein conjugates
|
NL8802046A
(nl)
|
1988-08-18 |
1990-03-16 |
Gen Electric |
Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
|
CA2006700A1
(en)
|
1989-01-17 |
1990-07-17 |
Antonello Pessi |
Synthetic peptides and their use as universal carriers for the preparation of immunogenic conjugates suitable for the development of synthetic vaccines
|
JPH04506662A
(ja)
|
1989-07-14 |
1992-11-19 |
アメリカン・サイアナミド・カンパニー |
接合体ワクチンのためのサイトカイニンおよびホルモンのキヤリヤー
|
IT1237764B
(it)
|
1989-11-10 |
1993-06-17 |
Eniricerche Spa |
Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
|
SE466259B
(sv)
|
1990-05-31 |
1992-01-20 |
Arne Forsgren |
Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
|
IE912559A1
(en)
|
1990-07-19 |
1992-01-29 |
Merck & Co Inc |
The class ii protein of the outer membrane of neisseria¹meningitidis, and vaccines containing same
|
ATE128628T1
(de)
|
1990-08-13 |
1995-10-15 |
American Cyanamid Co |
Faser-hemagglutinin von bordetella pertussis als träger für konjugierten impfstoff.
|
IT1262896B
(it)
|
1992-03-06 |
1996-07-22 |
|
Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
|
IL102687A
(en)
|
1992-07-30 |
1997-06-10 |
Yeda Res & Dev |
Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
|
US5425946A
(en)
|
1992-08-31 |
1995-06-20 |
North American Vaccine, Inc. |
Vaccines against group C Neisseria meningitidis
|
PT658118E
(pt)
|
1992-08-31 |
2002-05-31 |
Baxter Healthcare Sa |
Vacinas contra neisseria meningitidis do grupo c
|
NL9201716A
(nl)
|
1992-10-02 |
1994-05-02 |
Nederlanden Staat |
Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
|
GB9407984D0
(en)
|
1994-04-22 |
1994-09-21 |
Marconi Gec Ltd |
Model generation
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6207646B1
(en)
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
US6429199B1
(en)
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
US5698438A
(en)
|
1994-10-18 |
1997-12-16 |
Oregon Health Sciences University |
Bacterial hemoglobin receptor gene
|
IL117483A
(en)
|
1995-03-17 |
2008-03-20 |
Bernard Brodeur |
MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
|
FR2734484B1
(fr)
|
1995-05-24 |
1997-06-27 |
Pasteur Merieux Serums Vacc |
Composition vaccinale liquide et procede de fabrication
|
CN1146444C
(zh)
*
|
1995-06-23 |
2004-04-21 |
史密斯克莱·比奇曼生物公司 |
含有吸附于磷酸铝上的多糖偶联抗原的疫苗组合物
|
DE19643772C1
(de)
|
1996-10-23 |
1998-06-18 |
Wasagchemie Sythen Gmbh |
Verfahren zum Herstellen von Sprengstoffen aus Alt-Explosivstoffen
|
US6472518B1
(en)
|
1996-10-24 |
2002-10-29 |
Centers For Disease Control And Prevention, As Represented By The Secretary, Department Of Health And Human Services |
Invasion associated genes from Neisseria meningitidis serogroup B
|
DE69737125T3
(de)
|
1996-10-31 |
2015-02-26 |
Human Genome Sciences, Inc. |
Streptococcus pneumoniae-Antigene und Impfstoffe
|
DK1005368T3
(da)
|
1997-03-10 |
2010-01-04 |
Ottawa Hospital Res Inst |
Anvendelse af nukleinsyrer, der indeholder ikke-metyleret CpG dinukleotid i kombination med alun som hjælpestoffer
|
AU7701098A
(en)
|
1997-05-28 |
1998-12-30 |
Michael A. Apicella |
Laft mutants of pathogenic gram-negative bacteria
|
GB9713156D0
(en)
|
1997-06-20 |
1997-08-27 |
Microbiological Res Authority |
Vaccines
|
US6914131B1
(en)
|
1998-10-09 |
2005-07-05 |
Chiron S.R.L. |
Neisserial antigens
|
US6645503B1
(en)
|
1998-03-10 |
2003-11-11 |
Wyeth Holdings Corporation |
Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria
|
DE19814925C2
(de)
*
|
1998-04-03 |
2000-10-05 |
Thomas Harrer |
Arzneimittel zur Induktion zytotoxischer T-Zellen
|
US20070026021A1
(en)
|
1998-05-01 |
2007-02-01 |
Chiron S.R.I. |
Neisseria meningitidis antigens and compositions
|
ES2304065T3
(es)
|
1998-05-01 |
2008-09-01 |
Novartis Vaccines And Diagnostics, Inc. |
Antigenos y composiciones de neisseria meningitidis.
|
EP1109576B1
(en)
|
1998-08-19 |
2009-10-21 |
Baxter Healthcare SA |
Immunogenic beta-propionamido-linked polysaccharide protein conjugate useful as a vaccine produced using an n-acryloylated polysaccharide
|
AU1202200A
(en)
|
1998-10-09 |
2000-05-01 |
Chiron Corporation |
Neisseria genomic sequences and methods of their use
|
CN1911959A
(zh)
*
|
1998-10-09 |
2007-02-14 |
希龙公司 |
奈瑟球菌基因组序列及其用途
|
DK1535928T3
(da)
|
1998-10-22 |
2008-10-20 |
Univ Montana |
Vaccinesammensætninger indeholdende Omp85-proteiner af Neisseria gonorrhoeae og Neisseria meningitidis
|
AU762369B2
(en)
|
1998-11-03 |
2003-06-26 |
De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur |
LPS with reduced toxicity from genetically modified gram negative bacteria
|
AU1626199A
(en)
|
1998-12-04 |
2000-06-26 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
A vi-repa conjugate vaccine for immunization against salmonella typhi
|
EP1880735A3
(en)
|
1999-03-19 |
2008-03-12 |
GlaxoSmithKline Biologicals S.A. |
Vaccine
|
JP2002541808A
(ja)
|
1999-04-09 |
2002-12-10 |
テクラブ, インコーポレイテッド |
ポリサッカリド結合体ワクチンのための組換えトキシンaタンパク質キャリア
|
BR0010361A
(pt)
|
1999-04-30 |
2003-06-10 |
Chiron Corp |
Seq ências genÈmicas de neisseria e uso destas
|
NZ581940A
(en)
|
1999-04-30 |
2011-07-29 |
Novartis Vaccines & Diagnostic |
Conserved neisserial antigens
|
AU783894B2
(en)
|
1999-05-19 |
2005-12-22 |
Novartis Vaccines And Diagnostics S.R.L. |
Combination neisserial compositions
|
US6531131B1
(en)
|
1999-08-10 |
2003-03-11 |
The United States Of America As Represented By The Department Of Health And Human Services |
Conjugate vaccine for Neisseria meningitidis
|
GB9923176D0
(en)
|
1999-09-30 |
1999-12-01 |
Smithkline Beecham Biolog |
Novel composition
|
RU2281956C2
(ru)
|
1999-10-29 |
2006-08-20 |
Чирон С.Р.Л. |
Антигенные пептиды neisseria
|
RU2002117308A
(ru)
|
1999-11-29 |
2004-03-10 |
Чирон Спа (It) |
85 кДа АНТИГЕН NEISSERIA
|
DK2289545T3
(en)
|
2000-01-17 |
2016-09-05 |
Glaxosmithkline Biologicals Sa |
Supplemented OMV vaccine against meningococcus
|
KR100698561B1
(ko)
|
2000-01-25 |
2007-03-21 |
더 유니버서티 어브 퀸슬랜드 |
Neisseria Meningitidis 표면 항원ΝhhΑ의 보존 부위를 포함하는 단백질
|
CN100473663C
(zh)
|
2000-02-28 |
2009-04-01 |
启龙股份公司 |
奈瑟球菌蛋白质的异源表达
|
GB0007432D0
(en)
|
2000-03-27 |
2000-05-17 |
Microbiological Res Authority |
Proteins for use as carriers in conjugate vaccines
|
AU2002309706A1
(en)
|
2001-05-11 |
2002-11-25 |
Aventis Pasteur, Inc. |
Novel meningitis conjugate vaccine
|
GB0118249D0
(en)
*
|
2001-07-26 |
2001-09-19 |
Chiron Spa |
Histidine vaccines
|
EP1409013B1
(en)
|
2001-07-26 |
2009-11-18 |
Novartis Vaccines and Diagnostics S.r.l. |
Vaccines comprising aluminium adjuvants and histidine
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
FR2828406B1
(fr)
|
2001-08-08 |
2005-06-24 |
Aventis Pasteur |
Composition vaccinale bivalente havi
|
MX339524B
(es)
|
2001-10-11 |
2016-05-30 |
Wyeth Corp |
Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
|
GB0129007D0
(en)
|
2001-12-04 |
2002-01-23 |
Chiron Spa |
Adjuvanted antigenic meningococcal compositions
|
US20050147624A1
(en)
|
2002-02-22 |
2005-07-07 |
Harold Jennings |
Synthesis of lipopolysaccharide-protein conjugate vaccines via the lipid a region following removal of the glycosidic phosphate residue
|
MXPA04009339A
(es)
|
2002-03-26 |
2005-01-25 |
Chiron Srl |
Sacaridos modificados que tienen estabilidad mejorada en agua.
|
JP2006500963A
(ja)
|
2002-08-02 |
2006-01-12 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
ワクチン組成物
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
US7785608B2
(en)
|
2002-08-30 |
2010-08-31 |
Wyeth Holdings Corporation |
Immunogenic compositions for the prevention and treatment of meningococcal disease
|
AU2003274511B2
(en)
|
2002-10-11 |
2009-06-04 |
Glaxosmithkline Biologicals S.A. |
Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
|
GB0227346D0
(en)
*
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
WO2004065603A2
(en)
|
2003-01-15 |
2004-08-05 |
Wyeth Holdings Corporation |
Methods for increasing neisseria protein expression
|
WO2004067030A2
(en)
|
2003-01-30 |
2004-08-12 |
Chiron Srl |
Injectable vaccines against multiple meningococcal serogroups
|
US20070253964A1
(en)
|
2003-04-16 |
2007-11-01 |
Zlotnick Gary W |
Novel Immunogenic Compositions for the Prevention and Treatment of Meningococcal Disease
|
BRPI0409492A
(pt)
|
2003-04-18 |
2006-05-02 |
Pharmacia & Up John Company Ll |
terapias de combinação
|
ES2397923T3
(es)
|
2003-10-02 |
2013-03-12 |
Novartis Ag |
Vacunas líquidas para múltiples serogrupos meningocócicos
|
GB0323103D0
(en)
|
2003-10-02 |
2003-11-05 |
Chiron Srl |
De-acetylated saccharides
|
US7484413B2
(en)
|
2003-12-12 |
2009-02-03 |
The Boeing Company |
Remote radius inspection tool for composite joints
|
GB0408977D0
(en)
*
|
2004-04-22 |
2004-05-26 |
Chiron Srl |
Immunising against meningococcal serogroup Y using proteins
|
GB0419408D0
(en)
|
2004-09-01 |
2004-10-06 |
Chiron Srl |
741 chimeric polypeptides
|
EP2682126B1
(en)
*
|
2005-01-27 |
2016-11-23 |
Children's Hospital & Research Center at Oakland |
GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
|
US7709001B2
(en)
|
2005-04-08 |
2010-05-04 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
US7955605B2
(en)
|
2005-04-08 |
2011-06-07 |
Wyeth Llc |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
ME01334B
(me)
|
2005-04-08 |
2013-12-20 |
Wyeth Llc |
Polivalentni pripravak konjugata pneumokoknog polisaharida s proteinom
|
US20070184072A1
(en)
|
2005-04-08 |
2007-08-09 |
Wyeth |
Multivalent pneumococcal polysaccharide-protein conjugate composition
|
MX2007012337A
(es)
|
2005-04-08 |
2007-11-21 |
Wyeth Corp |
Separacion de contaminantes de polisacarido de streptococcus pneumoniae por manipulacion de ph.
|
MX2007016403A
(es)
|
2005-06-27 |
2008-03-07 |
Glaxosmithkline Biolog Sa |
Composicion inmunogenica.
|
GB0524066D0
(en)
*
|
2005-11-25 |
2006-01-04 |
Chiron Srl |
741 ii
|
AR058592A1
(es)
|
2005-12-22 |
2008-02-13 |
Glaxosmithkline Biolog Sa |
Vacuna
|
TW200806315A
(en)
|
2006-04-26 |
2008-02-01 |
Wyeth Corp |
Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
|
ATE450271T1
(de)
|
2006-06-12 |
2009-12-15 |
Glaxosmithkline Biolog Sa |
Impfstoff
|
MX2009003730A
(es)
|
2006-10-10 |
2009-04-22 |
Wyeth Corp |
Purificacion de polisacaridos de streptococcus pneumoniae tipo 3.
|
AR064642A1
(es)
|
2006-12-22 |
2009-04-15 |
Wyeth Corp |
Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
|
GB0700562D0
(en)
|
2007-01-11 |
2007-02-21 |
Novartis Vaccines & Diagnostic |
Modified Saccharides
|
WO2008125985A2
(en)
|
2007-04-11 |
2008-10-23 |
Novartis Ag |
Blocking interaction between pathogen factors and factor h to inhibit hemorrhagic syndromes
|
CA2688268A1
(en)
*
|
2007-06-04 |
2008-12-11 |
Novartis Ag |
Formulation of meningitis vaccines
|
CA2695467A1
(en)
*
|
2007-08-02 |
2009-03-26 |
Children's Hospital & Research Center At Oakland |
Fhbp- and lpxl1-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
|
CA2716212A1
(en)
|
2008-02-21 |
2009-08-27 |
Novartis Ag |
Meningococcal fhbp polypeptides
|
US9511131B2
(en)
|
2008-03-10 |
2016-12-06 |
Children's Hospital & Research Center Oakland |
Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use
|
EP2331562A4
(en)
|
2008-09-03 |
2012-07-04 |
Childrens Hosp & Res Ct Oak |
PEPTIDES WITH AN EPITOPE OF A DOMAIN OF THE FACTOR H-BINDING PROTEIN AND METHOD OF USE
|
IT1394288B1
(it)
*
|
2008-09-12 |
2012-06-06 |
Novartis Vaccines & Diagnostic |
Immunogeni di proteine che legano il fattore h.
|
GB0819633D0
(en)
|
2008-10-25 |
2008-12-03 |
Isis Innovation |
Composition
|
CA2756522C
(en)
|
2009-03-24 |
2018-06-26 |
Novartis Ag |
Adjuvanting meningococcal factor h binding protein
|
JP5668049B2
(ja)
|
2009-03-24 |
2015-02-12 |
ノバルティス アーゲー |
髄膜炎菌h因子結合タンパク質および肺炎球菌糖結合体の組み合わせ
|
EP2493499A1
(en)
|
2009-10-27 |
2012-09-05 |
Novartis AG |
Modified meningococcal fhbp polypeptides
|
JP2013521770A
(ja)
|
2010-03-10 |
2013-06-13 |
グラクソスミスクライン バイオロジカルズ ソシエテ アノニム |
ワクチン組成物
|
EP3327028B1
(en)
|
2010-03-30 |
2022-03-16 |
Children's Hospital & Research Center at Oakland |
Factor h binding proteins (fhbp) with altered properties and methods of use thereof
|
PE20140173A1
(es)
|
2010-09-10 |
2014-02-20 |
Wyeth Llc |
Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis
|
CN104428008B
(zh)
|
2012-05-24 |
2020-10-09 |
美国政府(由卫生和人类服务部的部长所代表) |
多价脑膜炎球菌缀合物及制备缀合物的方法
|
RU2015106930A
(ru)
|
2012-09-06 |
2016-10-20 |
Новартис Аг |
Комбинированные вакцины с менингококком серогруппы в и к/д/с
|