SI2364302T1 - Tirazinski analogi in njihova uporaba kot terapevtska sredstva in diagnostične sonde - Google Patents
Tirazinski analogi in njihova uporaba kot terapevtska sredstva in diagnostične sondeInfo
- Publication number
- SI2364302T1 SI2364302T1 SI200931578A SI200931578A SI2364302T1 SI 2364302 T1 SI2364302 T1 SI 2364302T1 SI 200931578 A SI200931578 A SI 200931578A SI 200931578 A SI200931578 A SI 200931578A SI 2364302 T1 SI2364302 T1 SI 2364302T1
- Authority
- SI
- Slovenia
- Prior art keywords
- therapeutic agents
- diagnostic probes
- triazine analogs
- triazine
- analogs
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 150000003918 triazines Chemical class 0.000 title 1
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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| PCT/IB2009/007404 WO2010052569A2 (en) | 2008-11-10 | 2009-11-10 | Triazine, pyrimidine and pyridine analogs and their use as therapeutic agents and diagnostic probes |
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| DE2013357A1 (en) * | 1970-03-20 | 1971-10-07 | Farbenfabriken Bayer AG,5O9O Lever kusen | Iminocarboxylic acid derivs in prepn of s-triazines |
| DE2712686C2 (de) * | 1977-03-23 | 1986-09-04 | Bayer Ag, 5090 Leverkusen | 4-Triazinyl-4'-benzoxazolyl- bzw. 4'-phenyl-stilben-derivate |
| JPS59145250A (ja) * | 1983-02-04 | 1984-08-20 | Mitsubishi Chem Ind Ltd | アントラキノン化合物及びアントラキノン染料 |
| GB8612062D0 (en) * | 1986-05-17 | 1986-06-25 | Fbc Ltd | Herbicides |
| EP0629622B1 (en) * | 1992-02-28 | 1998-11-11 | Zenyaku Kogyo Kabushikikaisha | S-triazine derivative and remedy for estrogen-dependent diseases containing the same as active ingredient |
| EP0775487A4 (en) * | 1994-08-08 | 1999-03-10 | Nippon Shinyaku Co Ltd | TRIAZINE DERIVATIVE AND MEDICINE |
| EP1126843A4 (en) * | 1998-10-29 | 2005-06-15 | Bristol Myers Squibb Co | AMINO-CELL DERIVATIVE COMPOUNDS INHIBITORS OF ENZYME IMPDH |
| AU3078000A (en) * | 1999-01-25 | 2000-08-07 | Zenyaku Kogyo Kabushiki Kaisha | Heterocyclic compounds and antitumor agents containing the same as the active ingredient |
| US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| ES2280530T3 (es) * | 2001-04-27 | 2007-09-16 | Zenyaku Kogyo Kabushiki Kaisha | Compuesto heterociclico y agente antitumoral que contiene el mismo como principio activo. |
| US20040009981A1 (en) * | 2002-03-15 | 2004-01-15 | David Bebbington | Compositions useful as inhibitors of protein kinases |
| EP1513827A1 (en) * | 2002-05-30 | 2005-03-16 | Solvay Pharmaceuticals B.V. | 1,3,5-triazine derivatives as ligands for human adenosine-a3 receptors |
| US20040082627A1 (en) * | 2002-06-21 | 2004-04-29 | Darrow James W. | Certain aromatic monocycles as kinase modulators |
| US7407962B2 (en) * | 2003-02-07 | 2008-08-05 | Vertex Pharmaceuticals Incorporated | Heteroaryl compounds useful as inhibitors or protein kinases |
| WO2005011703A1 (en) * | 2003-08-04 | 2005-02-10 | Akzo Nobel N.V. | 2-cyano-1,3,5-triazine-4,6-diamine derivatives |
| PE20050952A1 (es) * | 2003-09-24 | 2005-12-19 | Novartis Ag | Derivados de isoquinolina como inhibidores de b-raf |
| CN101137382B (zh) * | 2005-03-11 | 2012-11-21 | 全药工业株式会社 | 含有杂环化合物作为活性成分的免疫抑制剂和抗肿瘤剂 |
| AU2006297351A1 (en) * | 2005-09-30 | 2007-04-12 | Vertex Pharmaceuticals Incorporated | Deazapurines useful as inhibitors of janus kinases |
| GB0520657D0 (en) * | 2005-10-11 | 2005-11-16 | Ludwig Inst Cancer Res | Pharmaceutical compounds |
| CA2650290C (en) * | 2006-04-26 | 2015-11-17 | Genentech, Inc. | Pharmaceutical compounds |
| CA2659604C (en) | 2006-08-08 | 2015-04-28 | Chugai Seiyaku Kabushiki Kaisha | Pyrimidine derivative as pi3k inhibitor and use thereof |
| WO2008032033A1 (en) * | 2006-09-14 | 2008-03-20 | Astrazeneca Ab | 4-benzimidazolyl-2-morpholino-6-piperazinylpyrimidine derivatives as pi3k and mtor inhibitors for the treatment of proliferative disorders |
| WO2008072850A1 (en) * | 2006-12-11 | 2008-06-19 | Amorepacific Corporation | Triazine derivatives having inhibitory activity against acetyl-coa carboxylase |
| CA2675558A1 (en) * | 2007-02-06 | 2008-08-14 | Novartis Ag | Pi 3-kinase inhibitors and methods of their use |
| WO2009093981A1 (en) * | 2008-01-23 | 2009-07-30 | S Bio Pte Ltd | Triazine compounds as kinase inhibitors |
| EP2082777A1 (en) * | 2008-01-27 | 2009-07-29 | Oncotherm Kft. | Flexible and porous large-area electrode for heating |
| DE202008001253U1 (de) * | 2008-01-28 | 2008-04-10 | Mirror Image Ag | Bildanzeigegerät |
| WO2009143313A1 (en) * | 2008-05-23 | 2009-11-26 | Wyeth | Triazine compounds as p13 kinase and mtor inhibitors |
| GB2465405A (en) * | 2008-11-10 | 2010-05-19 | Univ Basel | Triazine, pyrimidine and pyridine analogues and their use in therapy |
-
2008
- 2008-11-10 GB GB0821219A patent/GB2465405A/en not_active Withdrawn
-
2009
- 2009-11-10 CN CN200980144674.6A patent/CN102209714B/zh active Active
- 2009-11-10 BR BRPI0921709-6A patent/BRPI0921709B1/pt active IP Right Grant
- 2009-11-10 CA CA2741990A patent/CA2741990C/en active Active
- 2009-11-10 AU AU2009312464A patent/AU2009312464B2/en active Active
- 2009-11-10 LT LTEP09764032.0T patent/LT2364302T/lt unknown
- 2009-11-10 NZ NZ592617A patent/NZ592617A/en active IP Right Revival
- 2009-11-10 ES ES09764032.0T patent/ES2609296T3/es active Active
- 2009-11-10 DK DK09764032.0T patent/DK2364302T3/en active
- 2009-11-10 RU RU2011114559/04A patent/RU2537945C2/ru active
- 2009-11-10 US US13/128,436 patent/US8921361B2/en active Active
- 2009-11-10 MX MX2011004889A patent/MX2011004889A/es active IP Right Grant
- 2009-11-10 JP JP2011535182A patent/JP5738768B2/ja active Active
- 2009-11-10 WO PCT/IB2009/007404 patent/WO2010052569A2/en not_active Ceased
- 2009-11-10 EP EP09764032.0A patent/EP2364302B1/en active Active
- 2009-11-10 SI SI200931578A patent/SI2364302T1/sl unknown
- 2009-11-10 KR KR1020117013081A patent/KR101749192B1/ko active Active
- 2009-11-10 HR HRP20161769TT patent/HRP20161769T1/hr unknown
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