SI1939204T1 - Kondenziran heterociklični derivat, medicinski sestavek, ki ta derivat vsebuje, in njegova medicinska uporaba - Google Patents

Kondenziran heterociklični derivat, medicinski sestavek, ki ta derivat vsebuje, in njegova medicinska uporaba

Info

Publication number
SI1939204T1
SI1939204T1 SI200631557T SI200631557T SI1939204T1 SI 1939204 T1 SI1939204 T1 SI 1939204T1 SI 200631557 T SI200631557 T SI 200631557T SI 200631557 T SI200631557 T SI 200631557T SI 1939204 T1 SI1939204 T1 SI 1939204T1
Authority
SI
Slovenia
Prior art keywords
medicinal
same
composition containing
fused heterocyclic
heterocyclic derivative
Prior art date
Application number
SI200631557T
Other languages
English (en)
Inventor
Kohsuke Ohno
Takashi Miyagi
Tomonaga Ozawa
Nobuhiko Fushimi
Original Assignee
Kissei Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co., Ltd. filed Critical Kissei Pharmaceutical Co., Ltd.
Publication of SI1939204T1 publication Critical patent/SI1939204T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Anesthesiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI200631557T 2005-10-19 2006-10-17 Kondenziran heterociklični derivat, medicinski sestavek, ki ta derivat vsebuje, in njegova medicinska uporaba SI1939204T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2005304395 2005-10-19
JP2006147019 2006-05-26
PCT/JP2006/320681 WO2007046392A1 (ja) 2005-10-19 2006-10-17 縮合複素環誘導体、それを含有する医薬組成物及びその医薬用途
EP06811925.4A EP1939204B3 (en) 2005-10-19 2006-10-17 Fused heterocyclic derivative, medicinal composition containing the same, and medicinal use thereof

Publications (1)

Publication Number Publication Date
SI1939204T1 true SI1939204T1 (sl) 2013-05-31

Family

ID=37962485

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631557T SI1939204T1 (sl) 2005-10-19 2006-10-17 Kondenziran heterociklični derivat, medicinski sestavek, ki ta derivat vsebuje, in njegova medicinska uporaba

Country Status (21)

Country Link
US (1) US9040693B2 (sl)
EP (1) EP1939204B3 (sl)
JP (2) JP4955566B2 (sl)
KR (1) KR101384132B1 (sl)
AU (1) AU2006305271B2 (sl)
BR (1) BRPI0617436B8 (sl)
CA (1) CA2624492C (sl)
CY (1) CY1113898T1 (sl)
DK (1) DK1939204T6 (sl)
ES (1) ES2398917T7 (sl)
HK (1) HK1125110A1 (sl)
IL (1) IL190754A (sl)
NL (1) NL301202I2 (sl)
NO (1) NO343185B1 (sl)
NZ (1) NZ567300A (sl)
PL (1) PL1939204T6 (sl)
PT (1) PT1939204E (sl)
RU (1) RU2418803C2 (sl)
SI (1) SI1939204T1 (sl)
TW (1) TWI400074B (sl)
WO (1) WO2007046392A1 (sl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA017029B1 (ru) 2007-04-06 2012-09-28 Ньюрокрайн Байосайенсиз, Инк. Антагонисты рецептора гонадотропин-рилизинг-фактора и способы их применения
AR065947A1 (es) * 2007-04-06 2009-07-15 Neurocrine Biosciences Inc Antagonistas de los receptores de la hormona liberadora de gonadodropina (gnrh)
CA2682519A1 (en) 2007-04-18 2008-11-06 Kissei Pharmaceutical Co., Ltd. Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes
EP2145889A4 (en) * 2007-04-18 2012-04-18 Kissei Pharmaceutical HETEROCYCLIC FUSED CORE DERIVATIVE, PHARMACEUTICAL COMPOSITION COMPRISING THE DERIVATIVE, AND USE OF THE COMPOSITION FOR MEDICAL PURPOSES
ES2502740T3 (es) * 2010-02-10 2014-10-06 Kissei Pharmaceutical Co., Ltd. Sal de derivado heterocíclico condensado y cristal del mismo
CN104755465A (zh) * 2012-08-24 2015-07-01 武田药品工业株式会社 杂环化合物
WO2014042176A1 (ja) * 2012-09-14 2014-03-20 キッセイ薬品工業株式会社 縮合複素環誘導体の製造方法およびその製造中間体
CN106132931B (zh) * 2014-01-06 2019-08-02 百时美施贵宝公司 碳环砜RORγ调节剂
TWI746613B (zh) * 2016-08-08 2021-11-21 日商橘生藥品工業股份有限公司 子宮內膜病症治療劑之用法及用量
AU2018217064A1 (en) * 2017-01-31 2019-08-08 Veru Inc. Compositions and methods for long term release of Gonadotropin-releasing hormone (GnRH) antagonists
AU2018280741B2 (en) 2017-06-05 2023-12-21 Kissei Pharmaceutical Co., Ltd. Gonadotropin-releasing hormone antagonist dosing regimens for treating uterine fibroids and reducing menstrual blood loss
SG11201911598WA (en) 2017-06-05 2020-01-30 ObsEva SA Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis
PE20211310A1 (es) * 2018-01-30 2021-07-22 Incyte Corp Procedimiento para la elaboracion de un recipiente de vidrio de sosa-cal a partir de materiales formadores de vidrio 100% reciclados y un recipiente de vidrio elaborado a partir de dicho procedimiento
CA3117092A1 (en) 2018-10-29 2020-05-07 ObsEva S.A. Compositions and methods for the treatment of adenomyosis and rectovaginal endometriosis
EP3876943A2 (en) 2018-11-07 2021-09-15 ObsEva S.A. Compositions and methods for the treatment of estrogen-dependent disorders
KR20220061120A (ko) 2019-08-08 2022-05-12 옵스에파 에스에이 에스트로겐-의존성 장애 치료용 조성물 및 방법
KR20220045198A (ko) * 2019-08-08 2022-04-12 옵스에파 에스에이 에스트로겐-의존성 장애의 치료를 위한 gnrh 길항제
WO2022179469A1 (zh) * 2021-02-23 2022-09-01 南京明德新药研发有限公司 噻吩并嘧啶二酮类化合物及其应用
EP4299569A1 (en) * 2021-02-23 2024-01-03 Soter Biopharma Pte. Ltd. Fused polycyclic substituted 5-carboxylic acid thienopyrimidine dione compound and use thereof
WO2024037532A1 (zh) * 2022-08-16 2024-02-22 深圳市康哲生物科技有限公司 一种噻吩并嘧啶酮衍生物的盐型及晶型

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69622677T2 (de) 1995-12-08 2003-03-20 Takeda Chemical Industries Ltd Hemmer der Prolaktinsynthese
AU2407997A (en) 1996-04-30 1997-11-19 Takeda Chemical Industries Ltd. Combined use of gnrh agonist and antagonist
JP2000511532A (ja) * 1996-05-20 2000-09-05 メルク エンド カンパニー インコーポレーテッド 性腺刺激ホルモン放出ホルモンのアンタゴニスト
GB0124627D0 (en) * 2001-10-15 2001-12-05 Smithkline Beecham Plc Novel compounds
WO2005049613A1 (en) 2003-11-14 2005-06-02 Merck Sharp & Dohme Limited Bicyclic pyrimidin-4-(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (vr1)
CA2547746A1 (en) 2003-12-19 2005-07-07 Merck & Co., Inc. Mitotic kinesin inhibitors
EP1847541A4 (en) 2005-02-03 2009-12-30 Takeda Pharmaceutical CONDENSED PYRIMIDINE DERIVATIVE AND USE THEREOF

Also Published As

Publication number Publication date
NO343185B1 (no) 2018-11-26
JP4955566B2 (ja) 2012-06-20
NL301202I2 (nl) 2023-01-24
NL301202I1 (nl) 2022-11-09
BRPI0617436B1 (pt) 2021-04-06
PT1939204E (pt) 2013-03-14
AU2006305271A1 (en) 2007-04-26
KR101384132B1 (ko) 2014-04-10
CY1113898T1 (el) 2016-07-27
IL190754A (en) 2012-10-31
WO2007046392A1 (ja) 2007-04-26
JP2012102140A (ja) 2012-05-31
RU2008119462A (ru) 2009-11-27
HK1125110A1 (en) 2009-07-31
BRPI0617436B8 (pt) 2021-05-25
NO20082249L (no) 2008-07-18
CA2624492A1 (en) 2007-04-26
EP1939204B3 (en) 2022-08-24
PL1939204T6 (pl) 2024-03-25
DK1939204T6 (da) 2022-09-05
EP1939204A1 (en) 2008-07-02
BRPI0617436A2 (pt) 2011-07-26
TW200732309A (en) 2007-09-01
JPWO2007046392A1 (ja) 2009-04-23
DK1939204T3 (da) 2013-03-11
AU2006305271B2 (en) 2011-11-17
EP1939204B1 (en) 2013-01-02
ES2398917T3 (es) 2013-03-22
US9040693B2 (en) 2015-05-26
KR20080063827A (ko) 2008-07-07
TWI400074B (zh) 2013-07-01
JP5319797B2 (ja) 2013-10-16
NZ567300A (en) 2010-11-26
RU2418803C2 (ru) 2011-05-20
US20090325900A1 (en) 2009-12-31
PL1939204T3 (pl) 2013-06-28
IL190754A0 (en) 2008-11-03
EP1939204A4 (en) 2010-09-01
ES2398917T7 (es) 2022-10-26
CA2624492C (en) 2014-02-18

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