PT1939204E - Derivado heterocíclico fundido, composição medicinal contendo o mesmo, e sua utilização medicinal - Google Patents
Derivado heterocíclico fundido, composição medicinal contendo o mesmo, e sua utilização medicinalInfo
- Publication number
- PT1939204E PT1939204E PT68119254T PT06811925T PT1939204E PT 1939204 E PT1939204 E PT 1939204E PT 68119254 T PT68119254 T PT 68119254T PT 06811925 T PT06811925 T PT 06811925T PT 1939204 E PT1939204 E PT 1939204E
- Authority
- PT
- Portugal
- Prior art keywords
- medicinal
- same
- composition containing
- fused heterocyclic
- heterocyclic derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Pregnancy & Childbirth (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005304395 | 2005-10-19 | ||
| JP2006147019 | 2006-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1939204E true PT1939204E (pt) | 2013-03-14 |
Family
ID=37962485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT68119254T PT1939204E (pt) | 2005-10-19 | 2006-10-17 | Derivado heterocíclico fundido, composição medicinal contendo o mesmo, e sua utilização medicinal |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US9040693B2 (pt) |
| EP (1) | EP1939204B3 (pt) |
| JP (2) | JP4955566B2 (pt) |
| KR (1) | KR101384132B1 (pt) |
| AU (1) | AU2006305271B2 (pt) |
| BR (1) | BRPI0617436B8 (pt) |
| CA (1) | CA2624492C (pt) |
| CY (1) | CY1113898T1 (pt) |
| DK (1) | DK1939204T6 (pt) |
| ES (1) | ES2398917T7 (pt) |
| HK (1) | HK1125110A1 (pt) |
| IL (1) | IL190754A (pt) |
| NL (1) | NL301202I2 (pt) |
| NO (1) | NO343185B1 (pt) |
| NZ (1) | NZ567300A (pt) |
| PL (1) | PL1939204T6 (pt) |
| PT (1) | PT1939204E (pt) |
| RU (1) | RU2418803C2 (pt) |
| SI (1) | SI1939204T1 (pt) |
| TW (1) | TWI400074B (pt) |
| WO (1) | WO2007046392A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PA8775801A1 (es) | 2007-04-06 | 2009-05-15 | Neurocrine Biosciences Inc | Antagonista del receptor de la hormona liberadora de gonadotropina y procedimientos relacionados con los mismos |
| US8263588B2 (en) | 2007-04-06 | 2012-09-11 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| JP5352449B2 (ja) * | 2007-04-18 | 2013-11-27 | キッセイ薬品工業株式会社 | 縮合へテロ環誘導体、それを含有する医薬組成物及びその医薬用途 |
| US20100130514A1 (en) * | 2007-04-18 | 2010-05-27 | Kissei Pharmaceutical Co., Ltd. | Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes |
| NZ601684A (en) | 2010-02-10 | 2013-08-30 | Kissei Pharmaceutical | Salt of fused heterocyclic derivative and crystal thereof |
| CN104755465A (zh) * | 2012-08-24 | 2015-07-01 | 武田药品工业株式会社 | 杂环化合物 |
| JP6268093B2 (ja) * | 2012-09-14 | 2018-01-24 | キッセイ薬品工業株式会社 | 縮合複素環誘導体の製造方法およびその製造中間体 |
| CN106132931B (zh) * | 2014-01-06 | 2019-08-02 | 百时美施贵宝公司 | 碳环砜RORγ调节剂 |
| US10646491B2 (en) * | 2016-08-08 | 2020-05-12 | Kissei Pharmaceutical Co., Ltd. | Usage and dosage of therapeutic agents for endometriosis |
| CA3052157A1 (en) * | 2017-01-31 | 2018-08-09 | Veru Inc. | Compositions and methods for long term release of ganadotropin-releasing hormone (gnrh) antagonists |
| EP3634418A1 (en) | 2017-06-05 | 2020-04-15 | ObsEva S.A. | Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis |
| EA201992812A1 (ru) | 2017-06-05 | 2020-05-21 | Обсева С.А. | Схемы применения антагониста гонадотропин-высвобождающего гормона для лечения миомы матки и уменьшения менструальной кровопотери |
| EA202091830A1 (ru) * | 2018-01-30 | 2020-12-29 | Инсайт Корпорейшн | Способы и промежуточные соединения для получения ингибитора jak |
| US20220117969A1 (en) | 2018-10-29 | 2022-04-21 | ObsEva S.A. | Compositions and methods for the treatment of adenomyosis and rectovaginal endometriosis |
| WO2020094698A2 (en) | 2018-11-07 | 2020-05-14 | ObsEva S.A. | Compositions and methods for the treatment of estrogen-dependent disorders |
| CA3150089A1 (en) * | 2019-08-08 | 2021-02-11 | ObsEva S.A. | Gnrh antagonists for the treatment of estrogen-dependent disorders |
| JP2022543308A (ja) | 2019-08-08 | 2022-10-11 | オブセヴァ エス．エー． | エストロゲン依存性障害の治療のための組成物及び方法 |
| WO2022179469A1 (zh) * | 2021-02-23 | 2022-09-01 | 南京明德新药研发有限公司 | 噻吩并嘧啶二酮类化合物及其应用 |
| CA3209363A1 (en) * | 2021-02-23 | 2022-09-01 | Kevin X Chen | Fused polycyclic substituted 5-carboxylic acid thienopyrimidine dione compound and use thereof |
| TW202342054A (zh) | 2022-02-04 | 2023-11-01 | 日商橘生藥品工業股份有限公司 | 經口固形製劑 |
| WO2024037532A1 (zh) * | 2022-08-16 | 2024-02-22 | 深圳市康哲生物科技有限公司 | 一种噻吩并嘧啶酮衍生物的盐型及晶型 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE221534T1 (de) * | 1995-12-08 | 2002-08-15 | Takeda Chemical Industries Ltd | Hemmer der prolaktinsynthese |
| CA2250908C (en) * | 1996-04-30 | 2012-03-13 | Takeda Chemical Industries, Ltd. | Combined use of gnrh agonist and antagonist |
| EP0901489A1 (en) | 1996-05-20 | 1999-03-17 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| GB0124627D0 (en) | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
| CA2545725A1 (en) | 2003-11-14 | 2005-06-02 | Merck Sharp & Dohme Limited | Bicyclic pyrimidin-4-(3h)-ones and analogues and derivatives thereof which modulate the function of the vanilloid-1 receptor (vr1) |
| JP2007514757A (ja) * | 2003-12-19 | 2007-06-07 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
| US20090062258A1 (en) * | 2005-02-03 | 2009-03-05 | Takeda Pharmaceutical Company Limited | Fused pyrimidine derivative and use thereof |
-
2006
- 2006-10-17 DK DK06811925.4T patent/DK1939204T6/da active
- 2006-10-17 EP EP06811925.4A patent/EP1939204B3/en active Active
- 2006-10-17 NZ NZ567300A patent/NZ567300A/en unknown
- 2006-10-17 PT PT68119254T patent/PT1939204E/pt unknown
- 2006-10-17 JP JP2007540993A patent/JP4955566B2/ja active Active
- 2006-10-17 ES ES06811925T patent/ES2398917T7/es active Active
- 2006-10-17 PL PL06811925.4T patent/PL1939204T6/pl unknown
- 2006-10-17 SI SI200631557T patent/SI1939204T1/sl unknown
- 2006-10-17 RU RU2008119462/04A patent/RU2418803C2/ru active
- 2006-10-17 WO PCT/JP2006/320681 patent/WO2007046392A1/ja active Application Filing
- 2006-10-17 AU AU2006305271A patent/AU2006305271B2/en active Active
- 2006-10-17 CA CA2624492A patent/CA2624492C/en active Active
- 2006-10-17 KR KR1020087010997A patent/KR101384132B1/ko active IP Right Grant
- 2006-10-17 US US12/089,674 patent/US9040693B2/en active Active
- 2006-10-17 BR BRPI0617436A patent/BRPI0617436B8/pt active IP Right Grant
- 2006-10-19 TW TW095138520A patent/TWI400074B/zh active
-
2008
- 2008-04-09 IL IL190754A patent/IL190754A/en active IP Right Grant
- 2008-05-19 NO NO20082249A patent/NO343185B1/no unknown
-
2009
- 2009-04-09 HK HK09103380.3A patent/HK1125110A1/xx unknown
-
2012
- 2012-01-19 JP JP2012008680A patent/JP5319797B2/ja active Active
-
2013
- 2013-04-02 CY CY20131100276T patent/CY1113898T1/el unknown
-
2022
- 2022-11-01 NL NL301202C patent/NL301202I2/nl unknown
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