SI1392672T1 - Chloromethylation of thiophene - Google Patents
Chloromethylation of thiopheneInfo
- Publication number
- SI1392672T1 SI1392672T1 SI200230143T SI200230143T SI1392672T1 SI 1392672 T1 SI1392672 T1 SI 1392672T1 SI 200230143 T SI200230143 T SI 200230143T SI 200230143 T SI200230143 T SI 200230143T SI 1392672 T1 SI1392672 T1 SI 1392672T1
- Authority
- SI
- Slovenia
- Prior art keywords
- thiophene
- formula
- chloromethylation
- compounds
- chloromethylated
- Prior art date
Links
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 title abstract 4
- 229930192474 thiophene Natural products 0.000 title abstract 2
- 238000007265 chloromethylation reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- FUOHKPSBGLXIRL-UHFFFAOYSA-N 2-(chloromethyl)thiophene Chemical compound ClCC1=CC=CS1 FUOHKPSBGLXIRL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Control Of Charge By Means Of Generators (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0102118A HU0102118D0 (en) | 2001-05-22 | 2001-05-22 | Process for chloromethylation |
| PCT/HU2002/000042 WO2002094806A1 (en) | 2001-05-22 | 2002-05-16 | Chloromethylation of thiophene |
| EP02727810A EP1392672B1 (en) | 2001-05-22 | 2002-05-16 | Chloromethylation of thiophene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1392672T1 true SI1392672T1 (en) | 2005-10-31 |
Family
ID=89979350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200230143T SI1392672T1 (en) | 2001-05-22 | 2002-05-16 | Chloromethylation of thiophene |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7462725B2 (zh) |
| EP (1) | EP1392672B1 (zh) |
| JP (1) | JP4467890B2 (zh) |
| KR (1) | KR100859386B1 (zh) |
| CN (1) | CN1260224C (zh) |
| AT (1) | ATE294790T1 (zh) |
| BR (1) | BRPI0209874B1 (zh) |
| CA (1) | CA2447440C (zh) |
| CZ (1) | CZ301166B6 (zh) |
| DE (1) | DE60204014T2 (zh) |
| DK (1) | DK1392672T3 (zh) |
| ES (1) | ES2240738T3 (zh) |
| HR (1) | HRP20031068B1 (zh) |
| HU (1) | HU0102118D0 (zh) |
| MX (1) | MXPA03010594A (zh) |
| PL (1) | PL210713B1 (zh) |
| PT (1) | PT1392672E (zh) |
| SI (1) | SI1392672T1 (zh) |
| SK (1) | SK285681B6 (zh) |
| WO (1) | WO2002094806A1 (zh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104513225A (zh) * | 2013-10-08 | 2015-04-15 | 华东师范大学 | 2-噻吩乙腈的制备方法 |
| CN103880741A (zh) * | 2014-02-28 | 2014-06-25 | 安徽国星生物化学有限公司 | 一种2-氯甲基-3，5-二甲基-4-烷氧基吡啶-n-氧化物的制备方法 |
| CN103992302A (zh) * | 2014-06-16 | 2014-08-20 | 商丘凯瑞达化工有限公司 | 2-噻吩乙酸合成工艺 |
| CN104327040A (zh) * | 2014-10-11 | 2015-02-04 | 华东师范大学 | 一种2-噻吩乙酸的合成方法 |
| WO2017139491A1 (en) * | 2016-02-10 | 2017-08-17 | Primus Green Energy Inc. | Single-loop octane enrichment |
| CN113896709B (zh) * | 2021-11-22 | 2023-02-28 | 南京一苇医药科技有限公司 | 一种苯并噻吩-3-乙酸的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527680A (en) * | 1945-06-21 | 1950-10-31 | Monsanto Chemicals | Alpha thenyl chloride from hydrogen chloride-formaldehyde solution and thiophene |
| GB639438A (en) * | 1948-02-25 | 1950-06-28 | Ici Ltd | Preparation of organic nitriles |
| US4501903A (en) * | 1983-07-05 | 1985-02-26 | Stauffer Chemical Company | Chloromethylation process |
| FR2608607B1 (fr) * | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
| PL158225B1 (en) * | 1989-06-09 | 1992-08-31 | Method for manufacturing 2-chlormethylthiopen |
-
2001
- 2001-05-22 HU HU0102118A patent/HU0102118D0/hu unknown
-
2002
- 2002-05-16 MX MXPA03010594A patent/MXPA03010594A/es active IP Right Grant
- 2002-05-16 SK SK1354-2003A patent/SK285681B6/sk not_active IP Right Cessation
- 2002-05-16 EP EP02727810A patent/EP1392672B1/en not_active Expired - Lifetime
- 2002-05-16 DE DE60204014T patent/DE60204014T2/de not_active Expired - Lifetime
- 2002-05-16 PT PT02727810T patent/PT1392672E/pt unknown
- 2002-05-16 PL PL363923A patent/PL210713B1/pl unknown
- 2002-05-16 AT AT02727810T patent/ATE294790T1/de active
- 2002-05-16 SI SI200230143T patent/SI1392672T1/xx unknown
- 2002-05-16 BR BRPI0209874A patent/BRPI0209874B1/pt not_active IP Right Cessation
- 2002-05-16 ES ES02727810T patent/ES2240738T3/es not_active Expired - Lifetime
- 2002-05-16 WO PCT/HU2002/000042 patent/WO2002094806A1/en active IP Right Grant
- 2002-05-16 CN CNB028103882A patent/CN1260224C/zh not_active Expired - Lifetime
- 2002-05-16 CZ CZ20032973A patent/CZ301166B6/cs not_active IP Right Cessation
- 2002-05-16 KR KR1020037015114A patent/KR100859386B1/ko active IP Right Grant
- 2002-05-16 US US10/478,238 patent/US7462725B2/en active Active
- 2002-05-16 JP JP2002591479A patent/JP4467890B2/ja not_active Expired - Fee Related
- 2002-05-16 CA CA2447440A patent/CA2447440C/en not_active Expired - Lifetime
- 2002-05-16 DK DK02727810T patent/DK1392672T3/da active
-
2003
- 2003-12-19 HR HR20031068A patent/HRP20031068B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SK285681B6 (sk) | 2007-06-07 |
| DK1392672T3 (da) | 2005-08-29 |
| PT1392672E (pt) | 2005-08-31 |
| KR20040018373A (ko) | 2004-03-03 |
| CZ301166B6 (cs) | 2009-11-25 |
| JP2004532247A (ja) | 2004-10-21 |
| US20060161008A1 (en) | 2006-07-20 |
| CN1511148A (zh) | 2004-07-07 |
| PL363923A1 (en) | 2004-11-29 |
| DE60204014T2 (de) | 2006-02-02 |
| KR100859386B1 (ko) | 2008-09-22 |
| CN1260224C (zh) | 2006-06-21 |
| CA2447440C (en) | 2010-10-19 |
| DE60204014D1 (de) | 2005-06-09 |
| WO2002094806A1 (en) | 2002-11-28 |
| HRP20031068A2 (en) | 2004-04-30 |
| SK13542003A3 (sk) | 2004-07-07 |
| BRPI0209874B1 (pt) | 2016-03-22 |
| BR0209874A (pt) | 2004-06-08 |
| CA2447440A1 (en) | 2002-11-28 |
| CZ20032973A3 (en) | 2004-03-17 |
| ATE294790T1 (de) | 2005-05-15 |
| US7462725B2 (en) | 2008-12-09 |
| EP1392672A1 (en) | 2004-03-03 |
| EP1392672B1 (en) | 2005-05-04 |
| JP4467890B2 (ja) | 2010-05-26 |
| HU0102118D0 (en) | 2001-07-30 |
| ES2240738T3 (es) | 2005-10-16 |
| HRP20031068B1 (en) | 2011-12-31 |
| MXPA03010594A (es) | 2004-04-02 |
| PL210713B1 (pl) | 2012-02-29 |
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