PT1392672E - Clorometilacao de tiofeno - Google Patents
Clorometilacao de tiofenoInfo
- Publication number
- PT1392672E PT1392672E PT02727810T PT02727810T PT1392672E PT 1392672 E PT1392672 E PT 1392672E PT 02727810 T PT02727810 T PT 02727810T PT 02727810 T PT02727810 T PT 02727810T PT 1392672 E PT1392672 E PT 1392672E
- Authority
- PT
- Portugal
- Prior art keywords
- thyophene
- formula
- chloromethyl acetate
- chloromethyl
- thiophene
- Prior art date
Links
- SMJYMSAPPGLBAR-UHFFFAOYSA-N chloromethyl acetate Chemical compound CC(=O)OCCl SMJYMSAPPGLBAR-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- FUOHKPSBGLXIRL-UHFFFAOYSA-N 2-(chloromethyl)thiophene Chemical compound ClCC1=CC=CS1 FUOHKPSBGLXIRL-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Control Of Charge By Means Of Generators (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0102118A HU0102118D0 (en) | 2001-05-22 | 2001-05-22 | Process for chloromethylation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1392672E true PT1392672E (pt) | 2005-08-31 |
Family
ID=89979350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT02727810T PT1392672E (pt) | 2001-05-22 | 2002-05-16 | Clorometilacao de tiofeno |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7462725B2 (pt) |
| EP (1) | EP1392672B1 (pt) |
| JP (1) | JP4467890B2 (pt) |
| KR (1) | KR100859386B1 (pt) |
| CN (1) | CN1260224C (pt) |
| AT (1) | ATE294790T1 (pt) |
| BR (1) | BRPI0209874B1 (pt) |
| CA (1) | CA2447440C (pt) |
| CZ (1) | CZ301166B6 (pt) |
| DE (1) | DE60204014T2 (pt) |
| DK (1) | DK1392672T3 (pt) |
| ES (1) | ES2240738T3 (pt) |
| HR (1) | HRP20031068B1 (pt) |
| HU (1) | HU0102118D0 (pt) |
| MX (1) | MXPA03010594A (pt) |
| PL (1) | PL210713B1 (pt) |
| PT (1) | PT1392672E (pt) |
| SI (1) | SI1392672T1 (pt) |
| SK (1) | SK285681B6 (pt) |
| WO (1) | WO2002094806A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104513225A (zh) * | 2013-10-08 | 2015-04-15 | 华东师范大学 | 2-噻吩乙腈的制备方法 |
| CN103880741A (zh) * | 2014-02-28 | 2014-06-25 | 安徽国星生物化学有限公司 | 一种2-氯甲基-3，5-二甲基-4-烷氧基吡啶-n-氧化物的制备方法 |
| CN103992302A (zh) * | 2014-06-16 | 2014-08-20 | 商丘凯瑞达化工有限公司 | 2-噻吩乙酸合成工艺 |
| CN104327040A (zh) * | 2014-10-11 | 2015-02-04 | 华东师范大学 | 一种2-噻吩乙酸的合成方法 |
| WO2017139491A1 (en) * | 2016-02-10 | 2017-08-17 | Primus Green Energy Inc. | Single-loop octane enrichment |
| CN113896709B (zh) * | 2021-11-22 | 2023-02-28 | 南京一苇医药科技有限公司 | 一种苯并噻吩-3-乙酸的合成方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2527680A (en) * | 1945-06-21 | 1950-10-31 | Monsanto Chemicals | Alpha thenyl chloride from hydrogen chloride-formaldehyde solution and thiophene |
| GB639438A (en) * | 1948-02-25 | 1950-06-28 | Ici Ltd | Preparation of organic nitriles |
| US4501903A (en) * | 1983-07-05 | 1985-02-26 | Stauffer Chemical Company | Chloromethylation process |
| FR2608607B1 (fr) * | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
| PL158225B1 (en) * | 1989-06-09 | 1992-08-31 | Method for manufacturing 2-chlormethylthiopen |
-
2001
- 2001-05-22 HU HU0102118A patent/HU0102118D0/hu unknown
-
2002
- 2002-05-16 ES ES02727810T patent/ES2240738T3/es not_active Expired - Lifetime
- 2002-05-16 KR KR1020037015114A patent/KR100859386B1/ko active IP Right Grant
- 2002-05-16 AT AT02727810T patent/ATE294790T1/de active
- 2002-05-16 EP EP02727810A patent/EP1392672B1/en not_active Expired - Lifetime
- 2002-05-16 US US10/478,238 patent/US7462725B2/en not_active Expired - Lifetime
- 2002-05-16 WO PCT/HU2002/000042 patent/WO2002094806A1/en active IP Right Grant
- 2002-05-16 PL PL363923A patent/PL210713B1/pl unknown
- 2002-05-16 CA CA2447440A patent/CA2447440C/en not_active Expired - Lifetime
- 2002-05-16 CZ CZ20032973A patent/CZ301166B6/cs not_active IP Right Cessation
- 2002-05-16 PT PT02727810T patent/PT1392672E/pt unknown
- 2002-05-16 SI SI200230143T patent/SI1392672T1/xx unknown
- 2002-05-16 BR BRPI0209874A patent/BRPI0209874B1/pt not_active IP Right Cessation
- 2002-05-16 MX MXPA03010594A patent/MXPA03010594A/es active IP Right Grant
- 2002-05-16 JP JP2002591479A patent/JP4467890B2/ja not_active Expired - Fee Related
- 2002-05-16 DK DK02727810T patent/DK1392672T3/da active
- 2002-05-16 CN CNB028103882A patent/CN1260224C/zh not_active Expired - Lifetime
- 2002-05-16 DE DE60204014T patent/DE60204014T2/de not_active Expired - Lifetime
- 2002-05-16 SK SK1354-2003A patent/SK285681B6/sk not_active IP Right Cessation
-
2003
- 2003-12-19 HR HR20031068A patent/HRP20031068B1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2447440A1 (en) | 2002-11-28 |
| CA2447440C (en) | 2010-10-19 |
| EP1392672A1 (en) | 2004-03-03 |
| HU0102118D0 (en) | 2001-07-30 |
| SK285681B6 (sk) | 2007-06-07 |
| US7462725B2 (en) | 2008-12-09 |
| DE60204014D1 (de) | 2005-06-09 |
| SK13542003A3 (sk) | 2004-07-07 |
| KR20040018373A (ko) | 2004-03-03 |
| JP4467890B2 (ja) | 2010-05-26 |
| PL363923A1 (en) | 2004-11-29 |
| BRPI0209874B1 (pt) | 2016-03-22 |
| PL210713B1 (pl) | 2012-02-29 |
| JP2004532247A (ja) | 2004-10-21 |
| BR0209874A (pt) | 2004-06-08 |
| MXPA03010594A (es) | 2004-04-02 |
| ATE294790T1 (de) | 2005-05-15 |
| CZ20032973A3 (en) | 2004-03-17 |
| EP1392672B1 (en) | 2005-05-04 |
| KR100859386B1 (ko) | 2008-09-22 |
| US20060161008A1 (en) | 2006-07-20 |
| CN1260224C (zh) | 2006-06-21 |
| HRP20031068B1 (en) | 2011-12-31 |
| ES2240738T3 (es) | 2005-10-16 |
| HRP20031068A2 (en) | 2004-04-30 |
| DK1392672T3 (da) | 2005-08-29 |
| WO2002094806A1 (en) | 2002-11-28 |
| DE60204014T2 (de) | 2006-02-02 |
| SI1392672T1 (en) | 2005-10-31 |
| CN1511148A (zh) | 2004-07-07 |
| CZ301166B6 (cs) | 2009-11-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FR17C0003I2 (fr) | Steroides comme agonistes de fxr | |
| NO20030845D0 (no) | Utvalgte fusjonerte pyrrolokarbazoler | |
| WO2003006425A3 (en) | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents | |
| CA2416867A1 (en) | Cyclopentanoindoles, compositions containing such compounds and methods of treatment | |
| EA200300065A1 (ru) | Окисленные сложные эфиры 4-йодфениламинобензгидроксамовых кислот | |
| BR0114045A (pt) | Poliarilcarboxamidas úteis como agentes redutores de lipìdeos | |
| DE60026404D1 (de) | Verfahren zur Herstellung von Benzothiophen-Derivaten | |
| ATE451123T1 (de) | Vaginal verabreichbare zusammensetzung zur behandlung von uteriner dysrhythmie | |
| WO2001064645A3 (en) | Derivatives of quinoline as alpha-2 antagonists | |
| SE9804212D0 (sv) | Compounds | |
| ATE363474T1 (de) | Benzimidazole zur behandlung sexueller fehlfunktionen | |
| DE60035429D1 (de) | Verwendung von sulfodehydroabietinsäure zur behandlung entzündlicher darmerkrankungen | |
| CY1106376T1 (el) | Δικυκλικα παραγωγα των αμινο-πυραζινονων, μεθοδος παρασκευης τους και οι φαρμακευτικες συνθεσεις που τα πepιεχουν | |
| PT1392672E (pt) | Clorometilacao de tiofeno | |
| DK1204658T3 (da) | Benzofurylpiperazin-serotoninagonister | |
| AU2002218337A1 (en) | Method for inducing cognition enhancement by use of trimethyl-bicyclo(2.2.1)heptane derivatives | |
| EE05182B1 (et) | Asendatud homopiperidlbensimidasooli analoog, meetod selle valmistamiseks ning seda sisaldav farmatseutiline kompositsioon | |
| AP2000001760A0 (en) | Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase. | |
| NO20033049L (no) | Fremgangsmåte for fremstilling av (+/-) trans-4-p-fluorfenyl- 3-hydroksymetyl-1-metylpiperidin | |
| WO2001083423A3 (en) | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | |
| SE9902596D0 (sv) | Pharmaceutically active compounds | |
| SE9902147L (sv) | Nya föreningar och farmaceutiska kompositioner innehållande desamma | |
| DE69824410D1 (en) | Antithrombosemittel | |
| MY128457A (en) | 2-aminocarbonyl-9h-purine derivatives |