SI1347984T1 - A process for the preparation of taxan derivatives - Google Patents

A process for the preparation of taxan derivatives

Info

Publication number
SI1347984T1
SI1347984T1 SI200130175T SI200130175T SI1347984T1 SI 1347984 T1 SI1347984 T1 SI 1347984T1 SI 200130175 T SI200130175 T SI 200130175T SI 200130175 T SI200130175 T SI 200130175T SI 1347984 T1 SI1347984 T1 SI 1347984T1
Authority
SI
Slovenia
Prior art keywords
preparation
taxan derivatives
taxan
derivatives
isobutylisoserinyl
Prior art date
Application number
SI200130175T
Other languages
English (en)
Slovenian (sl)
Inventor
Alessandro Pontiroli
Ezio Bombardelli
Original Assignee
Indena S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena S.P.A. filed Critical Indena S.P.A.
Publication of SI1347984T1 publication Critical patent/SI1347984T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
SI200130175T 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives SI1347984T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT2000MI002553A IT1320107B1 (it) 2000-11-28 2000-11-28 Procedimento per la preparazione di derivati tassanici.
PCT/EP2001/013614 WO2002044161A2 (en) 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives
EP01990433A EP1347984B1 (en) 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives

Publications (1)

Publication Number Publication Date
SI1347984T1 true SI1347984T1 (en) 2005-02-28

Family

ID=11446144

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130175T SI1347984T1 (en) 2000-11-28 2001-11-22 A process for the preparation of taxan derivatives

Country Status (23)

Country Link
US (1) US6737534B2 (cs)
EP (1) EP1347984B1 (cs)
JP (1) JP4237490B2 (cs)
KR (1) KR100799393B1 (cs)
CN (1) CN1243005C (cs)
AT (1) ATE275149T1 (cs)
AU (2) AU2956302A (cs)
CA (1) CA2430070C (cs)
CZ (1) CZ300793B6 (cs)
DE (1) DE60105314T2 (cs)
DK (1) DK1347984T3 (cs)
ES (1) ES2227316T3 (cs)
HU (1) HUP0302765A3 (cs)
IL (2) IL156141A0 (cs)
IT (1) IT1320107B1 (cs)
NO (1) NO328143B1 (cs)
PL (1) PL362392A1 (cs)
PT (1) PT1347984E (cs)
RU (1) RU2275365C2 (cs)
SI (1) SI1347984T1 (cs)
SK (1) SK286711B6 (cs)
TR (1) TR200402546T4 (cs)
WO (1) WO2002044161A2 (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012186A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
EP1712552A1 (en) * 2005-04-11 2006-10-18 INDENA S.p.A. Semisynthesis process for the preparation of 10-deacetyl-n-debenzoyl-paclitaxel
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US7232916B1 (en) 2006-05-11 2007-06-19 Indena S.P.A. Process for the preparation of a taxane derivative
DK1854799T3 (da) * 2006-05-12 2011-07-18 Indena Spa Fremgangsmåde til fremstilling af et taxanderivat
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
EP2080764B1 (en) 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel
CN104650109B (zh) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254517B (it) * 1992-03-06 1995-09-25 Indena Spa 14-beta idrossi-10-deacetil-baccatina iii, suoi derivati, loro prepazione ed impiego terapeutico
FR2696462B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ITMI991483A1 (it) 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1318678B1 (it) * 2000-08-10 2003-08-27 Indena Spa Procedimento per la preparazione di derivati della baccatina iii.

Also Published As

Publication number Publication date
EP1347984B1 (en) 2004-09-01
US6737534B2 (en) 2004-05-18
HUP0302765A3 (en) 2005-02-28
ES2227316T3 (es) 2005-04-01
AU2002229563B2 (en) 2006-03-30
CN1243005C (zh) 2006-02-22
DE60105314T2 (de) 2005-09-29
PL362392A1 (pl) 2004-11-02
SK286711B6 (sk) 2009-03-05
KR20030051864A (ko) 2003-06-25
CN1478091A (zh) 2004-02-25
HUP0302765A2 (hu) 2003-11-28
NO20032401D0 (no) 2003-05-27
ATE275149T1 (de) 2004-09-15
HK1059778A1 (en) 2004-07-16
EP1347984A2 (en) 2003-10-01
CA2430070A1 (en) 2002-06-06
ITMI20002553A1 (it) 2002-05-28
CZ20031474A3 (cs) 2003-08-13
IL156141A0 (en) 2003-12-23
KR100799393B1 (ko) 2008-01-30
NO328143B1 (no) 2009-12-14
WO2002044161A2 (en) 2002-06-06
CZ300793B6 (cs) 2009-08-12
CA2430070C (en) 2011-09-13
IT1320107B1 (it) 2003-11-18
DK1347984T3 (da) 2005-01-10
NO20032401L (no) 2003-05-27
US20040030164A1 (en) 2004-02-12
JP2004519434A (ja) 2004-07-02
PT1347984E (pt) 2004-11-30
RU2275365C2 (ru) 2006-04-27
WO2002044161A3 (en) 2002-07-25
AU2956302A (en) 2002-06-11
TR200402546T4 (tr) 2004-12-21
IL156141A (en) 2007-02-11
DE60105314D1 (de) 2004-10-07
JP4237490B2 (ja) 2009-03-11
SK6422003A3 (en) 2003-11-04

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