SI1326628T1 - Chemokine mutants in the treatment of multiple sclerosis - Google Patents

Chemokine mutants in the treatment of multiple sclerosis

Info

Publication number
SI1326628T1
SI1326628T1 SI200130130T SI200130130T SI1326628T1 SI 1326628 T1 SI1326628 T1 SI 1326628T1 SI 200130130 T SI200130130 T SI 200130130T SI 200130130 T SI200130130 T SI 200130130T SI 1326628 T1 SI1326628 T1 SI 1326628T1
Authority
SI
Slovenia
Prior art keywords
treatment
multiple sclerosis
chemokine mutants
chemokine
mutants
Prior art date
Application number
SI200130130T
Other languages
English (en)
Slovenian (sl)
Inventor
Amanda Proudfoot
Timothy N.C. Wells
Marie Kosco-Vilbois
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of SI1326628T1 publication Critical patent/SI1326628T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI200130130T 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis SI1326628T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP00121665 2000-10-04
EP01986265A EP1326628B1 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis
PCT/EP2001/011428 WO2002028419A2 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number Publication Date
SI1326628T1 true SI1326628T1 (en) 2004-10-31

Family

ID=8170011

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200130130T SI1326628T1 (en) 2000-10-04 2001-10-03 Chemokine mutants in the treatment of multiple sclerosis

Country Status (31)

Country Link
US (1) US7402303B2 (cs)
EP (1) EP1326628B1 (cs)
JP (1) JP3908165B2 (cs)
KR (1) KR100837898B1 (cs)
CN (1) CN1285381C (cs)
AR (1) AR030854A1 (cs)
AT (1) ATE265222T1 (cs)
AU (2) AU1591902A (cs)
BG (1) BG66137B1 (cs)
BR (1) BR0114407A (cs)
CA (1) CA2423616C (cs)
CZ (1) CZ303409B6 (cs)
DE (1) DE60103078T2 (cs)
DK (1) DK1326628T3 (cs)
EA (1) EA006137B1 (cs)
EE (1) EE05174B1 (cs)
ES (1) ES2217199T3 (cs)
HK (1) HK1062811A1 (cs)
HR (1) HRP20030215B1 (cs)
HU (1) HUP0302194A3 (cs)
IL (2) IL155178A0 (cs)
MX (1) MXPA03003008A (cs)
NO (1) NO330278B1 (cs)
PL (1) PL204231B1 (cs)
PT (1) PT1326628E (cs)
RS (1) RS50738B (cs)
SI (1) SI1326628T1 (cs)
SK (1) SK287523B6 (cs)
UA (1) UA77950C2 (cs)
WO (1) WO2002028419A2 (cs)
ZA (1) ZA200302315B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1458756B1 (en) 2001-12-17 2009-01-28 Laboratoires Serono SA Chemokine mutants acting as chemokine antagonists
SI1494703T1 (sl) * 2002-04-04 2006-06-30 Applied Research Systems Mutanti hemokinov z izboljsano oralno biorazpolozljivostjo
JP2006514699A (ja) * 2002-12-23 2006-05-11 アプライド リサーチ システムズ アルス ホールディング ナムローゼ フエンノートシャップ 肝疾患に対するｃｃケモカイン変異体の使用
US20090022657A1 (en) * 2003-10-22 2009-01-22 Applied Research Systems Ars Holding N.V. Novel CXCL8 antagonists
AT412785B (de) * 2003-12-04 2005-07-25 Kungl Andreas J Dr Gag-bindungsproteine
ES2257642T3 (es) * 2004-01-19 2006-08-01 Ares Trading S.A. Procedimiento para la purificacion de proteinas expresadas bacterialmente.
GB0412400D0 (en) * 2004-06-03 2004-07-07 Univ Newcastle Treatment of inflammatory conditions
EP2218748B1 (en) * 2005-09-03 2012-10-10 Samsung SDI Co., Ltd. Polybenzoxazine-based compound, electrolyte membrane including the same, and fuel cell employing the electrolyte membrane
GB0614755D0 (en) 2006-07-25 2006-09-06 Univ Geneve Cytokine derivatives
CA2695237A1 (en) 2007-08-02 2009-04-30 Novimmune S.A. Anti-rantes antibodies and methods of use thereof
US9034313B2 (en) * 2010-02-08 2015-05-19 The Trustees Of The University Of Pennsylvania Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same
CA3101052A1 (en) 2018-05-28 2019-12-05 ORION Biotechnology Switzerland Sarl Methods of inhibiting cerebral inflammation
WO2022093857A1 (en) * 2020-10-26 2022-05-05 City Of Hope Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
WO1998006751A1 (en) 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (en) * 1997-09-29 1999-04-07 Applied Research Systems ARS Holding N.V. Amino-terminal truncated c-c chemokines as chemokine antagonist
DK1431391T3 (da) * 1997-12-23 2005-12-19 San Raffaele Centro Fond RANTES-mutanter og terapeutiske anvendelser heraf
JP2002535376A (ja) * 1999-01-29 2002-10-22 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Ｃｃｒ１アンタゴニストを用いた脱髄性炎症性疾患の治療方法

Also Published As

Publication number Publication date
MXPA03003008A (es) 2003-07-14
EP1326628A2 (en) 2003-07-16
AU1591902A (en) 2002-04-15
EA006137B1 (ru) 2005-10-27
US20040101509A1 (en) 2004-05-27
UA77950C2 (en) 2007-02-15
IL155178A (en) 2009-07-20
US7402303B2 (en) 2008-07-22
DK1326628T3 (da) 2004-08-09
NO330278B1 (no) 2011-03-21
CN1477969A (zh) 2004-02-25
PL362350A1 (en) 2004-10-18
PT1326628E (pt) 2004-09-30
NO20031525D0 (no) 2003-04-03
ZA200302315B (en) 2004-03-25
EP1326628B1 (en) 2004-04-28
HUP0302194A3 (en) 2005-12-28
HRP20030215A2 (en) 2005-02-28
SK287523B6 (sk) 2011-01-04
KR100837898B1 (ko) 2008-06-13
KR20030034238A (ko) 2003-05-01
BR0114407A (pt) 2003-07-29
CA2423616C (en) 2010-03-16
EE200300139A (et) 2003-06-16
DE60103078T2 (de) 2005-04-07
NO20031525L (no) 2003-04-03
EA200300439A1 (ru) 2003-08-28
ES2217199T3 (es) 2004-11-01
CZ303409B6 (cs) 2012-09-05
BG66137B1 (bg) 2011-07-29
BG107685A (bg) 2003-11-28
ATE265222T1 (de) 2004-05-15
HK1062811A1 (en) 2004-11-26
RS50738B (sr) 2010-08-31
EE05174B1 (et) 2009-06-15
JP3908165B2 (ja) 2007-04-25
PL204231B1 (pl) 2009-12-31
WO2002028419A3 (en) 2002-06-13
CN1285381C (zh) 2006-11-22
JP2004510426A (ja) 2004-04-08
HRP20030215B1 (en) 2011-09-30
DE60103078D1 (de) 2004-06-03
CZ2003947A3 (cs) 2003-11-12
WO2002028419A2 (en) 2002-04-11
AR030854A1 (es) 2003-09-03
IL155178A0 (en) 2003-11-23
YU25703A (sh) 2006-05-25
HUP0302194A2 (hu) 2003-10-28
CA2423616A1 (en) 2002-04-11
SK4062003A3 (en) 2003-08-05
AU2002215919B2 (en) 2005-11-24

Similar Documents

Publication Publication Date Title
AU4244200A (en) Multi-functional therapeutic compress and methods of using the same
ZA983452B (en) Substituted pyrrolopyridines useful in the treatment of inflammatory diseases.
AU2001234837A1 (en) Azapeptides useful in the treatment of hepatitis c
AU1591902A (en) Chemokine mutants in the treatment of multiple sclerosis
PL344451A1 (en) Use of cyclosporins in the treatment of inflammatory autoimmune diseases
AU2524702A (en) The caveolin-1 gene and polypeptide encoded thereby and methods of use thereof
ZA975288B (en) The use of TCET in the prophylaxis and treatment of allergies.
AU1334602A (en) Osteopontin-coated surfaces and methods of use
AU2002243363A1 (en) Use of aziridino-compounds in the treatment of immune dysfunctions
EP1222212A4 (en) MUTANTS OF IL-13
HUP0400262A3 (en) Glycopeptides, their preparation and use in the treatment of multiple sclerosis
IL152996A0 (en) Novel interferon for the treatment of multiple sclerosis
AU5565401A (en) Materials and methods for the treatment of depression
AU2002210763A1 (en) Use of 1-ebio in the treatment of bipolar disorders
AU8609201A (en) Reduction of the electrocardiographic ot interval
GB0114231D0 (en) Treatment of multiple sclerosis
IL162507A (en) Use of ifnar2 mutants in the manufacture of medicaments
EP1229795A4 (en) CHIMIOKINE BETA 13 HUMAN
AU2001235003A1 (en) Novel human lysozymes and polynucleotides encoding the same
AU3264202A (en) Novel human kinases and polynucleotides encoding the same
IL146940A0 (en) Novel calpains and their use
AU1134702A (en) Novel human proteases and polynucleotides encoding the same
AU2002215312A1 (en) Human proteases and polynucleotides encoding the same
AU2146801A (en) Novel polypeptide- colipase 12 and polynucleotide encoding it
AU5025801A (en) Novel polypeptide---a human hexose kinase 13 and polynucleotide encoding it