SI1212321T1 - Intermediates for the production of naphthyridine-3-carboxylic acid derivatives - Google Patents
Intermediates for the production of naphthyridine-3-carboxylic acid derivativesInfo
- Publication number
- SI1212321T1 SI1212321T1 SI200030481T SI200030481T SI1212321T1 SI 1212321 T1 SI1212321 T1 SI 1212321T1 SI 200030481 T SI200030481 T SI 200030481T SI 200030481 T SI200030481 T SI 200030481T SI 1212321 T1 SI1212321 T1 SI 1212321T1
- Authority
- SI
- Slovenia
- Prior art keywords
- naphthyridine
- intermediates
- production
- carboxylic acid
- acid derivatives
- Prior art date
Links
- CGXLVFZJJOXEDF-UHFFFAOYSA-N 1,8-naphthyridine-3-carboxylic acid Chemical class N1=CC=CC2=CC(C(=O)O)=CN=C21 CGXLVFZJJOXEDF-UHFFFAOYSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9920919.9A GB9920919D0 (en) | 1999-09-03 | 1999-09-03 | Novel compound |
| EP00956706A EP1212321B1 (en) | 1999-09-03 | 2000-09-01 | Intermediates for the production of naphthyridine-3-carboxylic acid derivatives |
| PCT/GB2000/003358 WO2001017961A2 (en) | 1999-09-03 | 2000-09-01 | Intermediates for the production of naphthyridine-3-carboxylic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1212321T1 true SI1212321T1 (en) | 2004-12-31 |
Family
ID=10860355
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200030481T SI1212321T1 (en) | 1999-09-03 | 2000-09-01 | Intermediates for the production of naphthyridine-3-carboxylic acid derivatives |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US6703512B1 (https=) |
| EP (1) | EP1212321B1 (https=) |
| JP (1) | JP4208463B2 (https=) |
| KR (1) | KR100705363B1 (https=) |
| CN (1) | CN1255402C (https=) |
| AR (1) | AR029452A1 (https=) |
| AT (1) | ATE270671T1 (https=) |
| AU (1) | AU773698B2 (https=) |
| BR (1) | BRPI0013750B8 (https=) |
| CA (1) | CA2383751C (https=) |
| CO (1) | CO5180620A1 (https=) |
| CZ (1) | CZ2002759A3 (https=) |
| DE (1) | DE60012028T2 (https=) |
| DK (1) | DK1212321T3 (https=) |
| ES (1) | ES2223570T3 (https=) |
| GB (1) | GB9920919D0 (https=) |
| HK (1) | HK1046908B (https=) |
| HU (1) | HU229391B1 (https=) |
| IL (2) | IL148441A0 (https=) |
| MX (1) | MXPA02002356A (https=) |
| MY (1) | MY126789A (https=) |
| NO (1) | NO322501B1 (https=) |
| NZ (1) | NZ517601A (https=) |
| PL (1) | PL206491B1 (https=) |
| PT (1) | PT1212321E (https=) |
| SI (1) | SI1212321T1 (https=) |
| TR (1) | TR200200548T2 (https=) |
| TW (1) | TWI264435B (https=) |
| WO (1) | WO2001017961A2 (https=) |
| ZA (1) | ZA200201779B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2281817C (en) * | 1999-06-29 | 2008-07-29 | Smithkline Beecham Corporation | Methods of use of fluoroquinolone compounds against maxillary sinus pathogenic bacteria |
| GB9920919D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel compound |
| GB9920917D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel process |
| EP1412078B1 (en) | 2001-08-02 | 2008-10-08 | LG Life Sciences Limited | Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one, gemifloxacin or a salt thereof |
| KR100517638B1 (ko) | 2002-04-08 | 2005-09-28 | 주식회사 엘지생명과학 | 게미플록사신 산염의 새로운 제조방법 |
| CN100358949C (zh) * | 2002-07-17 | 2008-01-02 | 西巴特殊化学品控股有限公司 | 制备喹吖啶酮颜料的氧化法 |
| KR100653334B1 (ko) * | 2003-03-07 | 2006-12-04 | 주식회사 엘지생명과학 | 4-아미노메틸-3-알콕시이미노피롤리딘 메탄설폰산염의 신규한 제조 방법 |
| US8822934B2 (en) * | 2006-11-03 | 2014-09-02 | Accuray Incorporated | Collimator changer |
| CN104693088B (zh) * | 2013-12-06 | 2018-01-05 | 常州市勇毅生物药业有限公司 | 一种吉米沙星侧链的制备方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57134482A (en) | 1981-02-13 | 1982-08-19 | Dainippon Pharmaceut Co Ltd | 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation |
| IN162769B (https=) | 1984-11-13 | 1988-07-09 | Kyorin Seiyaku Kk | |
| NZ222047A (en) | 1986-10-08 | 1991-01-29 | Bristol Myers Co | Quinoline - or naphthyridine - carboxylic acid anti-bacterial agents |
| JPH01100165A (ja) | 1987-10-13 | 1989-04-18 | Shionogi & Co Ltd | オキシムまたはヒドロキシアミン誘導体系抗菌剤 |
| US4920120A (en) | 1988-01-25 | 1990-04-24 | Warner-Lambert Company | Antibacterial agents |
| JPH0356479A (ja) | 1989-07-24 | 1991-03-12 | Takeshi Yokota | 水溶性キノロン誘導体のｐ‐トルエンスルホン酸塩 |
| IE66202B1 (en) | 1989-08-16 | 1995-12-13 | Pfizer | Azabicyclo quinolone carboxylic acids |
| US5137892A (en) | 1990-12-12 | 1992-08-11 | Abbott Laboratories | Quinoline, naphthyridine and pyridobenzoxazine derivatives |
| EP0541086A1 (en) | 1991-11-08 | 1993-05-12 | Kaken Pharmaceutical Co., Ltd. | Antibacterial 6-fluoro-quinolones having an oxime group on the substituent in position 7 |
| JPH0673056A (ja) | 1992-08-26 | 1994-03-15 | Kaken Pharmaceut Co Ltd | キノリンカルボン酸誘導体およびその塩 |
| US5776944A (en) | 1994-06-16 | 1998-07-07 | Lg Chemical Ltd. | 7-(4-aminomethyl-3-methyloxyiminopyrroplidin-1-yl)-1-cyclopropyl-6-flu oro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid and the process for the preparation thereof |
| DK0688772T3 (da) | 1994-06-16 | 1999-11-01 | Lg Chemical Ltd | Quinolincarboxylsyrederivater med 7-(4-aminomethyl-3-oxim)-pyrrolidinsubstituenter og fremgangsmåde til deres fremstilling |
| JP3449658B2 (ja) | 1994-12-21 | 2003-09-22 | 杏林製薬株式会社 | 安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法 |
| US5763454A (en) | 1995-06-06 | 1998-06-09 | Pfizer, Inc. | Crystal form of anhydrous 7-( 1α,5α,6α!-6-amino-3-azabicyclo 3.1.0!hex-3-yl)-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8 naphthyridine-3-carboxylic acid, methanessulfonic acid salt |
| NZ309134A (en) | 1995-08-11 | 1999-09-29 | Pfizer | (1s,2s)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin-1-yl)-1- propranolmethanesulfonate trihydrate |
| AU726694B2 (en) | 1996-03-29 | 2000-11-16 | Smithkline Beecham Corporation | Eprosartan dihydrate and a process for its production and formulation |
| MA24500A1 (fr) * | 1997-03-21 | 1998-10-01 | Lg Life Sciences Ltd | Derive du sel d'acide carboxylique de naphthyridine . |
| KR100286874B1 (ko) | 1998-03-04 | 2001-04-16 | 성재갑 | 보호된 4-아미노메틸-피롤리딘-3-온의 제조방법 |
| ATE249432T1 (de) | 1998-05-29 | 2003-09-15 | Upjohn Co | 3-((1'-n-methylamino)ethyl-n-benzyl)pyrrolidin- monomethanesulfonat |
| GB9820405D0 (en) | 1998-09-18 | 1998-11-11 | Smithkline Beecham Plc | Process |
| DK1223935T3 (da) | 1999-06-29 | 2008-02-04 | Lg Life Sciences Ltd | Anvendelse af gemifloxacinforbindelser mod bakterier |
| WO2001015695A1 (en) | 1999-09-01 | 2001-03-08 | Smithkline Beecham Corporation | Methods of use of fluoroquinolone compounds against bacteria |
| GB9920917D0 (en) | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel process |
| GB9920919D0 (en) * | 1999-09-03 | 1999-11-10 | Sb Pharmco Inc | Novel compound |
| WO2001021176A1 (en) | 1999-09-22 | 2001-03-29 | Smithkline Beecham Corporation | Methods of use of fluoroquinolone compounds against bacteria |
| KR20010091379A (ko) | 2000-03-15 | 2001-10-23 | 성재갑 | 7-(4-아미노메틸-3-옥심)피롤리딘 치환체를 갖는 퀴놀린카르복실산 유도체의 신규 제조방법 |
| KR20020018560A (ko) | 2000-09-01 | 2002-03-08 | 성재갑 | 3-아미노메틸-4-ｚ-메톡시이미노피롤리딘의 신규 제조방법 |
-
1999
- 1999-09-03 GB GBGB9920919.9A patent/GB9920919D0/en not_active Ceased
-
2000
- 2000-09-01 CO CO00065923A patent/CO5180620A1/es active IP Right Grant
- 2000-09-01 AT AT00956706T patent/ATE270671T1/de active
- 2000-09-01 SI SI200030481T patent/SI1212321T1/xx unknown
- 2000-09-01 HK HK02108460.2A patent/HK1046908B/en not_active IP Right Cessation
- 2000-09-01 CA CA2383751A patent/CA2383751C/en not_active Expired - Lifetime
- 2000-09-01 CZ CZ2002759A patent/CZ2002759A3/cs unknown
- 2000-09-01 PT PT00956706T patent/PT1212321E/pt unknown
- 2000-09-01 AU AU68573/00A patent/AU773698B2/en not_active Ceased
- 2000-09-01 WO PCT/GB2000/003358 patent/WO2001017961A2/en not_active Ceased
- 2000-09-01 AR ARP000104596A patent/AR029452A1/es active IP Right Grant
- 2000-09-01 DE DE60012028T patent/DE60012028T2/de not_active Expired - Lifetime
- 2000-09-01 BR BRPI0013750A patent/BRPI0013750B8/pt not_active IP Right Cessation
- 2000-09-01 US US10/088,149 patent/US6703512B1/en not_active Expired - Lifetime
- 2000-09-01 PL PL354725A patent/PL206491B1/pl not_active IP Right Cessation
- 2000-09-01 CN CNB008123292A patent/CN1255402C/zh not_active Expired - Lifetime
- 2000-09-01 NZ NZ517601A patent/NZ517601A/en not_active IP Right Cessation
- 2000-09-01 IL IL14844100A patent/IL148441A0/xx active IP Right Grant
- 2000-09-01 TR TR2002/00548T patent/TR200200548T2/xx unknown
- 2000-09-01 MX MXPA02002356A patent/MXPA02002356A/es active IP Right Grant
- 2000-09-01 MY MYPI20004053 patent/MY126789A/en unknown
- 2000-09-01 KR KR1020027002876A patent/KR100705363B1/ko not_active Expired - Lifetime
- 2000-09-01 JP JP2001521708A patent/JP4208463B2/ja not_active Expired - Fee Related
- 2000-09-01 ES ES00956706T patent/ES2223570T3/es not_active Expired - Lifetime
- 2000-09-01 HU HU0202733A patent/HU229391B1/hu not_active IP Right Cessation
- 2000-09-01 EP EP00956706A patent/EP1212321B1/en not_active Expired - Lifetime
- 2000-09-01 DK DK00956706T patent/DK1212321T3/da active
- 2000-09-29 TW TW089120154A patent/TWI264435B/zh not_active IP Right Cessation
-
2002
- 2002-02-28 IL IL148441A patent/IL148441A/en unknown
- 2002-03-01 NO NO20021043A patent/NO322501B1/no not_active IP Right Cessation
- 2002-03-04 ZA ZA200201779A patent/ZA200201779B/xx unknown
-
2003
- 2003-12-23 US US10/742,797 patent/US6803467B2/en not_active Expired - Lifetime
-
2004
- 2004-09-08 US US10/935,357 patent/US20050033064A1/en not_active Abandoned
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