SI1115725T1 - Tetrahydropyridoethers - Google Patents
TetrahydropyridoethersInfo
- Publication number
- SI1115725T1 SI1115725T1 SI9930207T SI9930207T SI1115725T1 SI 1115725 T1 SI1115725 T1 SI 1115725T1 SI 9930207 T SI9930207 T SI 9930207T SI 9930207 T SI9930207 T SI 9930207T SI 1115725 T1 SI1115725 T1 SI 1115725T1
- Authority
- SI
- Slovenia
- Prior art keywords
- tetrahydropyridoethers
- naphthyridine
- imidazo
- methoxyethoxy
- tetrahydro
- Prior art date
Links
- PWILYDZRJORZDR-MISYRCLQSA-N (7r,8r,9r)-7-(2-methoxyethoxy)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridin-8-ol Chemical compound C1([C@@H]2[C@@H](O)[C@@H](C3=C(C4=NC(C)=C(C)N4C=C3)N2)OCCOC)=CC=CC=C1 PWILYDZRJORZDR-MISYRCLQSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98117988 | 1998-09-23 | ||
| DE19843504 | 1998-09-23 | ||
| PCT/EP1999/006899 WO2000017200A1 (en) | 1998-09-23 | 1999-09-17 | Tetrahydropyridoethers |
| EP99948776A EP1115725B1 (en) | 1998-09-23 | 1999-09-17 | Tetrahydropyridoethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1115725T1 true SI1115725T1 (en) | 2003-06-30 |
Family
ID=26049024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9930207T SI1115725T1 (en) | 1998-09-23 | 1999-09-17 | Tetrahydropyridoethers |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US6436953B1 (cs) |
| EP (1) | EP1115725B1 (cs) |
| JP (1) | JP4145492B2 (cs) |
| KR (1) | KR100668400B1 (cs) |
| CN (2) | CN100506821C (cs) |
| AT (1) | ATE231862T1 (cs) |
| AU (1) | AU763463B2 (cs) |
| BG (1) | BG65195B1 (cs) |
| BR (1) | BR9914044A (cs) |
| CA (1) | CA2344251A1 (cs) |
| CZ (1) | CZ292335B6 (cs) |
| DE (1) | DE69905178T2 (cs) |
| DK (1) | DK1115725T3 (cs) |
| EA (1) | EA005377B1 (cs) |
| EE (1) | EE04677B1 (cs) |
| ES (1) | ES2191464T3 (cs) |
| GE (1) | GEP20032926B (cs) |
| HK (1) | HK1038360B (cs) |
| HR (1) | HRP20010224A2 (cs) |
| HU (1) | HUP0102990A3 (cs) |
| ID (1) | ID28896A (cs) |
| IL (2) | IL142063A0 (cs) |
| NO (1) | NO317304B1 (cs) |
| NZ (1) | NZ510610A (cs) |
| PL (1) | PL193616B1 (cs) |
| PT (1) | PT1115725E (cs) |
| RS (1) | RS50145B (cs) |
| SI (1) | SI1115725T1 (cs) |
| SK (1) | SK285165B6 (cs) |
| TR (1) | TR200100805T2 (cs) |
| WO (1) | WO2000017200A1 (cs) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000017200A1 (en) | 1998-09-23 | 2000-03-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahydropyridoethers |
| ES2199810T3 (es) | 1999-04-17 | 2004-03-01 | Altana Pharma Ag | Haloalcoxi-imidazonaftiridinas. |
| CA2721484A1 (en) * | 1999-05-12 | 2000-11-12 | President And Fellows Of Harvard College | Dopamine transporter imaging agents |
| JP2003528878A (ja) * | 2000-03-29 | 2003-09-30 | アルタナ ファルマ アクチエンゲゼルシャフト | イミダゾピリジン誘導体のプロドラッグ |
| US6696461B2 (en) * | 2000-03-29 | 2004-02-24 | Altana Pharma Ag | Tricyclic imidazopyridines |
| US6869949B2 (en) | 2000-10-25 | 2005-03-22 | Altana Pharma Ag | Polysubstituted imidazopyridines as gastric secretion inhibitors |
| UA80393C2 (uk) | 2000-12-07 | 2007-09-25 | Алтана Фарма Аг | Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці |
| CN1496259A (zh) * | 2001-03-08 | 2004-05-12 | 新用途 | |
| ATE336493T1 (de) | 2001-08-02 | 2006-09-15 | Altana Pharma Ag | Tricyclische epoxide |
| US20040235882A1 (en) * | 2001-08-03 | 2004-11-25 | Jorg Senn-Bilfinger | Amino-substituted imidazopyridines for the treatment of gastrointestial diseases |
| IL159555A0 (en) * | 2001-08-03 | 2004-06-01 | Altana Pharma Ag | Alkyl-substituted imidazopyridine derivatives and pharmaceutical compositions containing the same |
| PL371413A1 (en) | 2002-02-15 | 2005-06-13 | Altana Pharma Ag | Tricyclic n-acyl compounds |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| HRP20041160A2 (en) * | 2002-05-07 | 2005-08-31 | Altana Pharma Ag | Novel combination for the treatment of airway disorders |
| EA008304B1 (ru) | 2002-11-19 | 2007-04-27 | Алтана Фарма Аг | 8-замещённые имидазопиридины |
| DE60323138D1 (de) | 2002-12-12 | 2008-10-02 | Nycomed Gmbh | Kombinationsarzneimittel aus r,r-formoterol und ciclesonide |
| EP1585516A2 (en) * | 2002-12-20 | 2005-10-19 | ALTANA Pharma AG | 8-trialkylsiloxy-2-methyl-9-phenyl-7-oxo-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridines |
| AU2004212337A1 (en) * | 2003-02-17 | 2004-08-26 | Altana Pharma Ag | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders |
| PT1606261E (pt) | 2003-03-10 | 2010-01-11 | Nycomed Gmbh | Novo processo para a preparação de roflumilast |
| TW200503783A (en) * | 2003-04-11 | 2005-02-01 | Altana Pharma Ag | Oral pharmaceutical preparation for proton pump antagonists |
| SA04250092B1 (ar) * | 2003-05-14 | 2008-05-04 | التانا فاروا ايه جي | مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً |
| JP2006528231A (ja) * | 2003-05-27 | 2006-12-14 | アルタナ ファルマ アクチエンゲゼルシャフト | プロトンポンプ阻害剤と胃腸運動性を変更する化合物との医薬品組合せ物 |
| CA2537182A1 (en) * | 2003-08-29 | 2005-03-10 | Dynogen Pharmaceuticals, Inc. | Compositions useful for treating gastrointestinal motility disorders |
| PT1670482E (pt) | 2003-09-16 | 2014-03-12 | Takeda Gmbh | Utilização de ciclesonida para o tratamento de doenças respiratórias |
| WO2005041961A1 (en) * | 2003-11-03 | 2005-05-12 | Astrazeneca Ab | Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux |
| AU2004298453A1 (en) | 2003-12-19 | 2005-06-30 | Altana Pharma Ag | Intermediates for the preparation of tricyclic dihydropyrano -imidazo -pyridines derivatives |
| AR047605A1 (es) * | 2004-02-17 | 2006-01-25 | Altana Pharma Ag | Imidazopiridinas triciclicas e intermediarios en la sintesis de las mismas,sus procesos de preparacion,composiciones farmaceuticas que los contienen y usos. |
| ES2373672T3 (es) | 2004-09-03 | 2012-02-07 | Yuhan Corporation | Derivados de pirrolo[2,3-c]piridina y procesos para su preparación. |
| MX2007002219A (es) | 2004-09-03 | 2007-05-04 | Yuhan Corp | Derivados de pirrolo [3,2-b ] piridina y procesos para su preparacion. |
| EP1784402B1 (en) | 2004-09-03 | 2011-08-03 | Yuhan Corporation | PYRROLO[3,2-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF |
| DK1861074T3 (da) * | 2005-03-16 | 2013-07-29 | Takeda Gmbh | Smagsmaskeret doseringsform indeholdende roflumilast |
| EP2080513A1 (en) * | 2008-01-16 | 2009-07-22 | Schraermeyer, Ulrich, Prof. Dr. rer. nat | Tetrahydropyridoethers for treatment of AMD |
| CN102470126A (zh) * | 2009-07-09 | 2012-05-23 | 拉夸里亚创药株式会社 | 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂 |
| WO2012027240A1 (en) * | 2010-08-23 | 2012-03-01 | Schering Corporation | Fused tricyclic inhibitors of mammalian target of rapamycin |
| CA2874988C (en) * | 2012-06-15 | 2016-05-24 | Bio-Pharm Solutions Co., Ltd. | Phenylalkyl sulfamate compound and muscle relaxant composition comprising the same |
| EP3054949A1 (en) | 2013-10-08 | 2016-08-17 | Katairo GmbH | Tetrahydropyridoethers for the treatment of stargardt's disease |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4468400A (en) * | 1982-12-20 | 1984-08-28 | Schering Corporation | Antiulcer tricyclic imidazo [1,2-a]pyridines |
| FI900219A0 (fi) | 1987-07-16 | 1990-01-15 | Byk Gulden Lomberg Chem Fab | Nya diazoler. |
| SE9401197D0 (sv) * | 1994-04-11 | 1994-04-11 | Astra Ab | Active compounds |
| AU702166B2 (en) * | 1994-07-28 | 1999-02-18 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Acylimidazopyridines |
| WO1998042707A1 (en) * | 1997-03-24 | 1998-10-01 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahydropyrido compounds |
| EE03771B1 (et) * | 1997-03-24 | 2002-06-17 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahüdropüridoühendid, neid sisaldav ravim ja nende kasutamine |
| WO2000017200A1 (en) * | 1998-09-23 | 2000-03-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Tetrahydropyridoethers |
-
1999
- 1999-09-17 WO PCT/EP1999/006899 patent/WO2000017200A1/en not_active Ceased
- 1999-09-17 JP JP2000574109A patent/JP4145492B2/ja not_active Expired - Lifetime
- 1999-09-17 CZ CZ20011082A patent/CZ292335B6/cs not_active IP Right Cessation
- 1999-09-17 DK DK99948776T patent/DK1115725T3/da active
- 1999-09-17 DE DE69905178T patent/DE69905178T2/de not_active Expired - Lifetime
- 1999-09-17 IL IL14206399A patent/IL142063A0/xx active IP Right Grant
- 1999-09-17 ES ES99948776T patent/ES2191464T3/es not_active Expired - Lifetime
- 1999-09-17 EA EA200100315A patent/EA005377B1/ru not_active IP Right Cessation
- 1999-09-17 BR BR9914044-6A patent/BR9914044A/pt not_active Application Discontinuation
- 1999-09-17 HK HK02100042.6A patent/HK1038360B/en not_active IP Right Cessation
- 1999-09-17 HU HU0102990A patent/HUP0102990A3/hu unknown
- 1999-09-17 PT PT99948776T patent/PT1115725E/pt unknown
- 1999-09-17 ID IDW20010682A patent/ID28896A/id unknown
- 1999-09-17 TR TR2001/00805T patent/TR200100805T2/xx unknown
- 1999-09-17 SK SK399-2001A patent/SK285165B6/sk not_active IP Right Cessation
- 1999-09-17 CN CNB2004100384351A patent/CN100506821C/zh not_active Expired - Fee Related
- 1999-09-17 NZ NZ510610A patent/NZ510610A/en unknown
- 1999-09-17 US US09/582,212 patent/US6436953B1/en not_active Expired - Lifetime
- 1999-09-17 AU AU61920/99A patent/AU763463B2/en not_active Expired
- 1999-09-17 GE GEAP19995786A patent/GEP20032926B/en unknown
- 1999-09-17 EP EP99948776A patent/EP1115725B1/en not_active Expired - Lifetime
- 1999-09-17 CA CA002344251A patent/CA2344251A1/en not_active Abandoned
- 1999-09-17 PL PL99346617A patent/PL193616B1/pl not_active IP Right Cessation
- 1999-09-17 CN CNB998112992A patent/CN1155598C/zh not_active Expired - Fee Related
- 1999-09-17 HR HR20010224A patent/HRP20010224A2/hr not_active Application Discontinuation
- 1999-09-17 SI SI9930207T patent/SI1115725T1/xx unknown
- 1999-09-17 AT AT99948776T patent/ATE231862T1/de not_active IP Right Cessation
- 1999-09-17 RS YUP-214/01A patent/RS50145B/sr unknown
- 1999-09-17 EE EEP200100172A patent/EE04677B1/xx not_active IP Right Cessation
- 1999-09-17 KR KR1020017003553A patent/KR100668400B1/ko not_active Expired - Fee Related
-
2001
- 2001-02-19 BG BG105270A patent/BG65195B1/bg unknown
- 2001-03-12 NO NO20011243A patent/NO317304B1/no not_active IP Right Cessation
- 2001-03-18 IL IL142063A patent/IL142063A/en not_active IP Right Cessation
-
2002
- 2002-03-25 US US10/103,733 patent/US6696460B2/en not_active Expired - Lifetime
-
2004
- 2004-02-23 US US10/783,512 patent/US7105676B2/en not_active Expired - Lifetime
-
2006
- 2006-07-27 US US11/493,707 patent/US7393860B1/en not_active Expired - Fee Related
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