SI0958282T1 - 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines - Google Patents

2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines

Info

Publication number
SI0958282T1
SI0958282T1 SI9830699T SI9830699T SI0958282T1 SI 0958282 T1 SI0958282 T1 SI 0958282T1 SI 9830699 T SI9830699 T SI 9830699T SI 9830699 T SI9830699 T SI 9830699T SI 0958282 T1 SI0958282 T1 SI 0958282T1
Authority
SI
Slovenia
Prior art keywords
substituted
pyridines
phenoxy
amino
Prior art date
Application number
SI9830699T
Other languages
English (en)
Slovenian (sl)
Inventor
John Adams Lowe Iii
Jolanta Nowakowski
Robert Alfred Volkmann
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of SI0958282T1 publication Critical patent/SI0958282T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Addiction (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI9830699T 1997-02-10 1998-01-29 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines SI0958282T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3753397P 1997-02-10 1997-02-10
EP98900635A EP0958282B1 (en) 1997-02-10 1998-01-29 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines
PCT/IB1998/000112 WO1998034919A1 (en) 1997-02-10 1998-01-29 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines

Publications (1)

Publication Number Publication Date
SI0958282T1 true SI0958282T1 (en) 2005-02-28

Family

ID=21894849

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830699T SI0958282T1 (en) 1997-02-10 1998-01-29 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines

Country Status (44)

Country Link
US (2) US20010007873A1 (no)
EP (1) EP0958282B1 (no)
JP (1) JP3505189B2 (no)
KR (1) KR100460399B1 (no)
CN (3) CN1246848A (no)
AP (1) AP833A (no)
AR (1) AR011117A1 (no)
AT (1) ATE271544T1 (no)
AU (1) AU744313B2 (no)
BG (1) BG103633A (no)
BR (1) BR9811093A (no)
CA (1) CA2277990C (no)
CO (1) CO4920225A1 (no)
CZ (1) CZ292135B6 (no)
DE (1) DE69825147T2 (no)
DK (1) DK0958282T3 (no)
DZ (1) DZ2414A1 (no)
EA (1) EA003834B1 (no)
ES (1) ES2224354T3 (no)
GT (1) GT199800032A (no)
HN (1) HN1998000030A (no)
HR (1) HRP980069A2 (no)
HU (1) HUP0000762A3 (no)
IL (1) IL130898A0 (no)
IS (1) IS5118A (no)
MA (1) MA27676A1 (no)
MY (1) MY120976A (no)
NO (1) NO314803B1 (no)
NZ (2) NZ518345A (no)
OA (1) OA11084A (no)
PA (1) PA8446301A1 (no)
PE (1) PE58599A1 (no)
PL (1) PL335161A1 (no)
PT (1) PT958282E (no)
SI (1) SI0958282T1 (no)
SK (1) SK101199A3 (no)
TN (1) TNSN98024A1 (no)
TR (1) TR199901917T2 (no)
TW (1) TW458969B (no)
UA (1) UA64740C2 (no)
UY (1) UY24881A1 (no)
WO (1) WO1998034919A1 (no)
YU (1) YU35699A (no)
ZA (1) ZA981017B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
DE69923448T2 (de) * 1998-06-03 2005-12-29 Pfizer Products Inc., Groton 2-aminopyridine mit kondensierten ringsubstituenten als stickstoff-oxid-synthase inhibitoren
CN1323211A (zh) * 1998-08-11 2001-11-21 辉瑞产品公司 Nos抑制剂的新药学用途
US7115557B2 (en) 1998-09-25 2006-10-03 Sciaticon Ab Use of certain drugs for treating nerve root injury
SE9803710L (sv) 1998-09-25 2000-03-26 A & Science Invest Ab Användning av vissa substanser för behandling av nervrotsskador
DK1155000T3 (da) 1999-02-25 2003-10-13 Pfizer Prod Inc 2-aminopyridiner som indeholder sammensluttede ringsubstituenser
FR2812635B1 (fr) * 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US20030232739A1 (en) * 2001-08-15 2003-12-18 Pfizer Inc. Pharmaceutical combinations comprising a NOS inhibitor and an NMDA receptor antagonist
US6803470B2 (en) 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
DOP2002000467A (es) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas
US7045652B2 (en) * 2002-07-03 2006-05-16 Pfizer Inc Processes for preparing substituted aryl boronic acids
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
WO2005007627A1 (ja) * 2003-07-18 2005-01-27 Nihon Nohyaku Co., Ltd. フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤
JP2008545616A (ja) * 2005-02-21 2008-12-18 プロキシマジェン エルティーディー ジスキネジーの阻害または治療
GB0607196D0 (en) * 2006-04-11 2006-05-17 Prosidion Ltd G-protein coupled receptor agonists
AR064572A1 (es) * 2006-12-28 2009-04-08 Basf Ag Derivados de piridina 2-sustituidas, una composicion farmaceutica que las comprende y su uso en la preparacion de un medicamento para el tratamiento del cancer.
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
ES2709195T3 (es) 2013-02-28 2019-04-15 Tiumbio Co Ltd Compuesto tricíclico y uso del mismo
EP3066072B1 (en) * 2013-11-07 2021-11-03 The University of Kansas Biphenylamide derivative hsp90 inhibitors
US10562858B2 (en) * 2014-08-13 2020-02-18 Meiji Seika Pharma Co., Ltd. Crystalline anti-trichophyton agents and preparation process thereof
CN106265640B (zh) * 2016-08-11 2019-05-14 吉林大学 Appa在制备治疗糖尿病肾病药物中的应用
CN108069831B (zh) * 2018-01-25 2020-11-24 上海恩氟佳科技有限公司 一种合成2,3-二甲基-4-氟苯酚的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08504798A (ja) * 1992-12-18 1996-05-21 ザ ウエルカム ファウンデーション リミテッド 酵素阻害薬としての,ピリミジン,ピリジン,プテリジノンおよびインダゾール誘導体
CN1077886C (zh) * 1993-10-21 2002-01-16 G·D·瑟尔公司 用作一氧化一氮合酶抑制剂的脒基衍生物
WO1996018616A1 (en) * 1994-12-12 1996-06-20 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
DE69728138T2 (de) * 1996-03-29 2004-09-16 Pfizer Inc. 6-phenylpyridinderivate

Also Published As

Publication number Publication date
HUP0000762A2 (hu) 2000-09-28
CN1523015A (zh) 2004-08-25
KR100460399B1 (ko) 2004-12-08
JP2000509408A (ja) 2000-07-25
UY24881A1 (es) 2000-12-29
US20030162765A1 (en) 2003-08-28
TW458969B (en) 2001-10-11
IL130898A0 (en) 2001-01-28
YU35699A (sh) 2002-06-19
DK0958282T3 (da) 2004-11-29
EA199900632A1 (ru) 2000-02-28
US20010007873A1 (en) 2001-07-12
TR199901917T2 (xx) 1999-12-21
NZ336623A (en) 2000-11-24
CN1515554A (zh) 2004-07-28
PA8446301A1 (es) 2000-05-24
HRP980069A2 (en) 1998-12-31
NO314803B1 (no) 2003-05-26
AP833A (en) 2000-05-10
CA2277990C (en) 2006-08-01
NO993823D0 (no) 1999-08-09
IS5118A (is) 1999-07-29
CA2277990A1 (en) 1998-08-13
HN1998000030A (es) 1998-10-22
PT958282E (pt) 2004-11-30
ZA981017B (en) 1999-08-10
NO993823L (no) 1999-08-09
BR9811093A (pt) 2000-07-18
ATE271544T1 (de) 2004-08-15
PL335161A1 (en) 2000-04-10
GT199800032A (es) 1998-02-11
EA003834B1 (ru) 2003-10-30
CZ276999A3 (cs) 2000-05-17
AR011117A1 (es) 2000-08-02
JP3505189B2 (ja) 2004-03-08
MA27676A1 (fr) 2006-01-02
KR20000070803A (ko) 2000-11-25
CZ292135B6 (cs) 2003-08-13
SK101199A3 (en) 2000-10-09
DZ2414A1 (fr) 2003-01-04
MY120976A (en) 2005-12-30
DE69825147T2 (de) 2005-08-04
EP0958282B1 (en) 2004-07-21
EP0958282A1 (en) 1999-11-24
NZ518345A (en) 2005-02-25
OA11084A (en) 2002-03-15
AU5572798A (en) 1998-08-26
UA64740C2 (uk) 2004-03-15
BG103633A (bg) 2000-11-30
CN1246848A (zh) 2000-03-08
WO1998034919A1 (en) 1998-08-13
CO4920225A1 (es) 2000-05-29
TNSN98024A1 (fr) 2005-03-15
ES2224354T3 (es) 2005-03-01
HUP0000762A3 (en) 2000-10-30
DE69825147D1 (de) 2004-08-26
PE58599A1 (es) 1999-06-12
AU744313B2 (en) 2002-02-21

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