SI0791577T1 - Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them - Google Patents

Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them

Info

Publication number
SI0791577T1
SI0791577T1 SI9730024T SI9730024T SI0791577T1 SI 0791577 T1 SI0791577 T1 SI 0791577T1 SI 9730024 T SI9730024 T SI 9730024T SI 9730024 T SI9730024 T SI 9730024T SI 0791577 T1 SI0791577 T1 SI 0791577T1
Authority
SI
Slovenia
Prior art keywords
medicament
benzylguanidines
ortho
substituted
preparation
Prior art date
Application number
SI9730024T
Other languages
English (en)
Slovenian (sl)
Inventor
Udo Dr. Albus
Joachim Dr. Brendel
Heinz-Werner Dr. Kleemann
Hans Jochen Dr. Lang
Wolfgang Dr. Scholz
Jan-Robert Dr. Schwark
Andreas Dr. Weichert
Original Assignee
Hoechst Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Aktiengesellschaft filed Critical Hoechst Aktiengesellschaft
Publication of SI0791577T1 publication Critical patent/SI0791577T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI9730024T 1996-02-22 1997-01-20 Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them SI0791577T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19606509A DE19606509A1 (de) 1996-02-22 1996-02-22 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP97100777A EP0791577B1 (de) 1996-02-22 1997-01-20 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
SI0791577T1 true SI0791577T1 (en) 2000-02-29

Family

ID=7786043

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730024T SI0791577T1 (en) 1996-02-22 1997-01-20 Ortho-substituted benzylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicament containing them

Country Status (30)

Country Link
US (1) US5856574A (ja)
EP (1) EP0791577B1 (ja)
JP (1) JP3974677B2 (ja)
KR (1) KR100476796B1 (ja)
CN (1) CN1060764C (ja)
AR (1) AR005933A1 (ja)
AT (1) ATE186296T1 (ja)
AU (1) AU723096B2 (ja)
BR (1) BR9701046A (ja)
CA (1) CA2198176A1 (ja)
CZ (1) CZ287843B6 (ja)
DE (2) DE19606509A1 (ja)
DK (1) DK0791577T3 (ja)
ES (1) ES2140922T3 (ja)
GR (1) GR3032293T3 (ja)
HR (1) HRP970101B1 (ja)
HU (1) HUP9700502A3 (ja)
ID (1) ID16042A (ja)
IL (1) IL120259A (ja)
MX (1) MX9701323A (ja)
MY (1) MY117642A (ja)
NO (1) NO307046B1 (ja)
NZ (1) NZ314268A (ja)
PL (1) PL185752B1 (ja)
RU (1) RU2218329C2 (ja)
SI (1) SI0791577T1 (ja)
SK (1) SK281753B6 (ja)
TR (1) TR199700144A2 (ja)
TW (1) TW404937B (ja)
ZA (1) ZA971514B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713427A1 (de) * 1997-04-01 1998-10-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CN111099959B (zh) * 2019-12-30 2022-09-02 西安瑞联新材料股份有限公司 一种1,4-二溴-2,5-二碘苯的工业化生产方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59403818D1 (de) * 1993-02-20 1997-10-02 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
US5596407A (en) * 1995-06-07 1997-01-21 Varian Associates, Inc Optical detector for echelle spectrometer

Also Published As

Publication number Publication date
AR005933A1 (es) 1999-07-21
HRP970101B1 (en) 2001-02-28
CA2198176A1 (en) 1997-08-22
CZ287843B6 (en) 2001-02-14
NZ314268A (en) 1997-11-24
HU9700502D0 (en) 1997-04-28
ID16042A (id) 1997-08-28
JP3974677B2 (ja) 2007-09-12
EP0791577B1 (de) 1999-11-03
IL120259A0 (en) 1997-06-10
BR9701046A (pt) 1998-12-15
KR100476796B1 (ko) 2005-07-21
IL120259A (en) 2001-05-20
TW404937B (en) 2000-09-11
ES2140922T3 (es) 2000-03-01
GR3032293T3 (en) 2000-04-27
PL185752B1 (pl) 2003-07-31
ATE186296T1 (de) 1999-11-15
HUP9700502A3 (en) 1998-01-28
JPH09227496A (ja) 1997-09-02
PL318417A1 (en) 1997-09-01
HUP9700502A2 (en) 1997-12-29
US5856574A (en) 1999-01-05
SK23797A3 (en) 1997-11-05
TR199700144A2 (tr) 1997-09-21
NO970798D0 (no) 1997-02-21
AU723096B2 (en) 2000-08-17
ZA971514B (en) 1997-08-22
DE19606509A1 (de) 1997-08-28
CN1161960A (zh) 1997-10-15
CN1060764C (zh) 2001-01-17
KR970061861A (ko) 1997-09-12
SK281753B6 (sk) 2001-07-10
NO970798L (no) 1997-08-25
HRP970101A2 (en) 1998-04-30
DE59700640D1 (de) 1999-12-09
AU1477397A (en) 1997-08-28
NO307046B1 (no) 2000-01-31
EP0791577A1 (de) 1997-08-27
CZ52897A3 (cs) 1998-06-17
RU2218329C2 (ru) 2003-12-10
DK0791577T3 (da) 2000-04-25
MX9701323A (es) 1997-08-30
MY117642A (en) 2004-07-31

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Legal Events

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Effective date: 20070828