MX9701323A - Benzoilguanidinas sustituidas en posicion orto, un procedimiento para su preparacion, utilizacion como medicamento o agente diagnostico, asi como medicamento que la contiene. - Google Patents
Benzoilguanidinas sustituidas en posicion orto, un procedimiento para su preparacion, utilizacion como medicamento o agente diagnostico, asi como medicamento que la contiene.Info
- Publication number
- MX9701323A MX9701323A MX9701323A MX9701323A MX9701323A MX 9701323 A MX9701323 A MX 9701323A MX 9701323 A MX9701323 A MX 9701323A MX 9701323 A MX9701323 A MX 9701323A MX 9701323 A MX9701323 A MX 9701323A
- Authority
- MX
- Mexico
- Prior art keywords
- medicament
- well
- ortho position
- preparation
- substituted benzoylguanidines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Las benzoilgunidinas sustituidas en posicion orto de la formula I en la que R(2) y R(3) tienen los significados indicados en las reivindicaciones, son apropiadas como medicamentos antiarrítmicos con una componente cardioprotectora para la profilaxis de los infartos y el tratamiento de los infartos, así como para el tratamiento de la angina de pecho. Éstas inhiben también previamente los procesos patofisiologicos al formarse lesiones inducidas isquémicamente, especialmente en la provocacion de arritmias cardíacas inducidas isquémicamente.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19606509A DE19606509A1 (de) | 1996-02-22 | 1996-02-22 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19606509.7 | 1996-02-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
MXPA97001323A MXPA97001323A (es) | 1997-08-01 |
MX9701323A true MX9701323A (es) | 1997-08-30 |
Family
ID=7786043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9701323A MX9701323A (es) | 1996-02-22 | 1997-02-21 | Benzoilguanidinas sustituidas en posicion orto, un procedimiento para su preparacion, utilizacion como medicamento o agente diagnostico, asi como medicamento que la contiene. |
Country Status (30)
Country | Link |
---|---|
US (1) | US5856574A (es) |
EP (1) | EP0791577B1 (es) |
JP (1) | JP3974677B2 (es) |
KR (1) | KR100476796B1 (es) |
CN (1) | CN1060764C (es) |
AR (1) | AR005933A1 (es) |
AT (1) | ATE186296T1 (es) |
AU (1) | AU723096B2 (es) |
BR (1) | BR9701046A (es) |
CA (1) | CA2198176A1 (es) |
CZ (1) | CZ287843B6 (es) |
DE (2) | DE19606509A1 (es) |
DK (1) | DK0791577T3 (es) |
ES (1) | ES2140922T3 (es) |
GR (1) | GR3032293T3 (es) |
HR (1) | HRP970101B1 (es) |
HU (1) | HUP9700502A3 (es) |
ID (1) | ID16042A (es) |
IL (1) | IL120259A (es) |
MX (1) | MX9701323A (es) |
MY (1) | MY117642A (es) |
NO (1) | NO307046B1 (es) |
NZ (1) | NZ314268A (es) |
PL (1) | PL185752B1 (es) |
RU (1) | RU2218329C2 (es) |
SI (1) | SI0791577T1 (es) |
SK (1) | SK281753B6 (es) |
TR (1) | TR199700144A2 (es) |
TW (1) | TW404937B (es) |
ZA (1) | ZA971514B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19713427A1 (de) * | 1997-04-01 | 1998-10-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
CN111099959B (zh) * | 2019-12-30 | 2022-09-02 | 西安瑞联新材料股份有限公司 | 一种1,4-二溴-2,5-二碘苯的工业化生产方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59403818D1 (de) * | 1993-02-20 | 1997-10-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament |
DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19517848A1 (de) * | 1995-05-16 | 1996-11-21 | Merck Patent Gmbh | Fluorhaltige Benzoylguanidine |
US5596407A (en) * | 1995-06-07 | 1997-01-21 | Varian Associates, Inc | Optical detector for echelle spectrometer |
-
1996
- 1996-02-22 DE DE19606509A patent/DE19606509A1/de not_active Withdrawn
-
1997
- 1997-01-20 AT AT97100777T patent/ATE186296T1/de not_active IP Right Cessation
- 1997-01-20 EP EP97100777A patent/EP0791577B1/de not_active Expired - Lifetime
- 1997-01-20 DE DE59700640T patent/DE59700640D1/de not_active Expired - Lifetime
- 1997-01-20 DK DK97100777T patent/DK0791577T3/da active
- 1997-01-20 SI SI9730024T patent/SI0791577T1/xx not_active IP Right Cessation
- 1997-01-20 ES ES97100777T patent/ES2140922T3/es not_active Expired - Lifetime
- 1997-02-11 PL PL97318417A patent/PL185752B1/pl not_active IP Right Cessation
- 1997-02-19 AU AU14773/97A patent/AU723096B2/en not_active Ceased
- 1997-02-19 NZ NZ314268A patent/NZ314268A/en unknown
- 1997-02-20 TR TR97/00144A patent/TR199700144A2/xx unknown
- 1997-02-20 TW TW086101993A patent/TW404937B/zh not_active IP Right Cessation
- 1997-02-20 CZ CZ1997528A patent/CZ287843B6/cs not_active IP Right Cessation
- 1997-02-20 MY MYPI97000647A patent/MY117642A/en unknown
- 1997-02-20 SK SK237-97A patent/SK281753B6/sk unknown
- 1997-02-20 IL IL12025997A patent/IL120259A/en not_active IP Right Cessation
- 1997-02-20 AR ARP970100687A patent/AR005933A1/es active IP Right Grant
- 1997-02-20 CN CN97102493A patent/CN1060764C/zh not_active Expired - Fee Related
- 1997-02-21 HR HR19606509.7 patent/HRP970101B1/xx not_active IP Right Cessation
- 1997-02-21 HU HU9700502A patent/HUP9700502A3/hu unknown
- 1997-02-21 CA CA002198176A patent/CA2198176A1/en not_active Abandoned
- 1997-02-21 MX MX9701323A patent/MX9701323A/es unknown
- 1997-02-21 KR KR1019970005214A patent/KR100476796B1/ko not_active IP Right Cessation
- 1997-02-21 NO NO970798A patent/NO307046B1/no unknown
- 1997-02-21 JP JP03724197A patent/JP3974677B2/ja not_active Expired - Fee Related
- 1997-02-21 BR BR9701046A patent/BR9701046A/pt not_active Application Discontinuation
- 1997-02-21 ZA ZA9701514A patent/ZA971514B/xx unknown
- 1997-02-21 US US08/804,023 patent/US5856574A/en not_active Expired - Lifetime
- 1997-02-21 RU RU97102581/04A patent/RU2218329C2/ru not_active IP Right Cessation
- 1997-02-24 ID IDP970554A patent/ID16042A/id unknown
-
1999
- 1999-12-30 GR GR990403381T patent/GR3032293T3/el unknown
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