HRP970101B1 - Ortho-substituted benzoylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicaments containing them - Google Patents

Ortho-substituted benzoylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicaments containing them

Info

Publication number
HRP970101B1
HRP970101B1 HRP970101A HRP970101B1 HR P970101 B1 HRP970101 B1 HR P970101B1 HR P970101 A HRP970101 A HR P970101A HR P970101 B1 HRP970101 B1 HR P970101B1
Authority
HR
Croatia
Prior art keywords
ortho
medicament
preparation
well
diagnostic agent
Prior art date
Application number
Other languages
English (en)
Inventor
Udo Albus
Joachim Brendel
Heinz-Werner Kleemann
Hans-Jochen Lang
Wolfgang Scholz
Jan-Robert Schwark
Andreas Weichert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HRP970101A2 publication Critical patent/HRP970101A2/hr
Publication of HRP970101B1 publication Critical patent/HRP970101B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HR19606509.7 1996-02-22 1997-02-21 Ortho-substituted benzoylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicaments containing them HRP970101B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19606509A DE19606509A1 (de) 1996-02-22 1996-02-22 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
HRP970101A2 HRP970101A2 (en) 1998-04-30
HRP970101B1 true HRP970101B1 (en) 2001-02-28

Family

ID=7786043

Family Applications (1)

Application Number Title Priority Date Filing Date
HR19606509.7 HRP970101B1 (en) 1996-02-22 1997-02-21 Ortho-substituted benzoylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicaments containing them

Country Status (30)

Country Link
US (1) US5856574A (ja)
EP (1) EP0791577B1 (ja)
JP (1) JP3974677B2 (ja)
KR (1) KR100476796B1 (ja)
CN (1) CN1060764C (ja)
AR (1) AR005933A1 (ja)
AT (1) ATE186296T1 (ja)
AU (1) AU723096B2 (ja)
BR (1) BR9701046A (ja)
CA (1) CA2198176A1 (ja)
CZ (1) CZ287843B6 (ja)
DE (2) DE19606509A1 (ja)
DK (1) DK0791577T3 (ja)
ES (1) ES2140922T3 (ja)
GR (1) GR3032293T3 (ja)
HR (1) HRP970101B1 (ja)
HU (1) HUP9700502A3 (ja)
ID (1) ID16042A (ja)
IL (1) IL120259A (ja)
MX (1) MX9701323A (ja)
MY (1) MY117642A (ja)
NO (1) NO307046B1 (ja)
NZ (1) NZ314268A (ja)
PL (1) PL185752B1 (ja)
RU (1) RU2218329C2 (ja)
SI (1) SI0791577T1 (ja)
SK (1) SK281753B6 (ja)
TR (1) TR199700144A2 (ja)
TW (1) TW404937B (ja)
ZA (1) ZA971514B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713427A1 (de) * 1997-04-01 1998-10-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CN111099959B (zh) * 2019-12-30 2022-09-02 西安瑞联新材料股份有限公司 一种1,4-二溴-2,5-二碘苯的工业化生产方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59403818D1 (de) * 1993-02-20 1997-10-02 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, als Inhibitoren des zellulären Na+/H+-Austauschs oder als Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19517848A1 (de) * 1995-05-16 1996-11-21 Merck Patent Gmbh Fluorhaltige Benzoylguanidine
US5596407A (en) * 1995-06-07 1997-01-21 Varian Associates, Inc Optical detector for echelle spectrometer

Also Published As

Publication number Publication date
AR005933A1 (es) 1999-07-21
CA2198176A1 (en) 1997-08-22
CZ287843B6 (en) 2001-02-14
NZ314268A (en) 1997-11-24
HU9700502D0 (en) 1997-04-28
ID16042A (id) 1997-08-28
JP3974677B2 (ja) 2007-09-12
EP0791577B1 (de) 1999-11-03
IL120259A0 (en) 1997-06-10
BR9701046A (pt) 1998-12-15
KR100476796B1 (ko) 2005-07-21
IL120259A (en) 2001-05-20
TW404937B (en) 2000-09-11
ES2140922T3 (es) 2000-03-01
GR3032293T3 (en) 2000-04-27
PL185752B1 (pl) 2003-07-31
ATE186296T1 (de) 1999-11-15
HUP9700502A3 (en) 1998-01-28
JPH09227496A (ja) 1997-09-02
PL318417A1 (en) 1997-09-01
HUP9700502A2 (en) 1997-12-29
US5856574A (en) 1999-01-05
SI0791577T1 (en) 2000-02-29
SK23797A3 (en) 1997-11-05
TR199700144A2 (tr) 1997-09-21
NO970798D0 (no) 1997-02-21
AU723096B2 (en) 2000-08-17
ZA971514B (en) 1997-08-22
DE19606509A1 (de) 1997-08-28
CN1161960A (zh) 1997-10-15
CN1060764C (zh) 2001-01-17
KR970061861A (ko) 1997-09-12
SK281753B6 (sk) 2001-07-10
NO970798L (no) 1997-08-25
HRP970101A2 (en) 1998-04-30
DE59700640D1 (de) 1999-12-09
AU1477397A (en) 1997-08-28
NO307046B1 (no) 2000-01-31
EP0791577A1 (de) 1997-08-27
CZ52897A3 (cs) 1998-06-17
RU2218329C2 (ru) 2003-12-10
DK0791577T3 (da) 2000-04-25
MX9701323A (es) 1997-08-30
MY117642A (en) 2004-07-31

Similar Documents

Publication Publication Date Title
AU699406B2 (en) Basically-substituted benzoylguanidines, a process for preparing them, their use as a medicament or diagnostic agent, and a medicament containing them
HRP970292A2 (en) Substituted 2-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicament containing them
AU6584696A (en) Substituted benzoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and medicament comprising them
AU2330095A (en) Ortho-amino-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent, and also a medicament containing them
HRP970304B1 (en) Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them
HRP970424B1 (en) Substituted indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic agents and medicaments containing them
ZA966106B (en) 4-flouroalkyl-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them.
GR3035811T3 (en) Substituted 1-naphtoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them
AU3900895A (en) Substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
HRP970332A2 (en) Ortho-substituted benzoylguanidines, process for their preparation, their use as medical or diagnostic agent as well as a medicament containing them
HRP970293A2 (en) Bis-ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent and medicaments containing them
HRP970101B1 (en) Ortho-substituted benzoylguanidines, process for their preparation and their use as medicament or diagnostic agent as well as medicaments containing them
HRP980169B1 (en) Ortho-substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent as well as medicaments containing them
HRP970126A2 (en) Ortho-substituted benzoylguanidines, processes for their preparation, their use as medicament or diagnostic material and medicaments containing them
IL120358A0 (en) Ortho-substituted benzoylguanidines process for their preparation their use as a medicament or diagnostic and medicaments comprising them

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20051221

Year of fee payment: 10

PBON Lapse due to non-payment of renewal fee

Effective date: 20070222