SI0626385T1 - Tetrahydropyran derivatives - Google Patents

Tetrahydropyran derivatives

Info

Publication number
SI0626385T1
SI0626385T1 SI9430457T SI9430457T SI0626385T1 SI 0626385 T1 SI0626385 T1 SI 0626385T1 SI 9430457 T SI9430457 T SI 9430457T SI 9430457 T SI9430457 T SI 9430457T SI 0626385 T1 SI0626385 T1 SI 0626385T1
Authority
SI
Slovenia
Prior art keywords
hydroxy groups
antiinflammatory
free
tetrahydropyran derivatives
various
Prior art date
Application number
SI9430457T
Other languages
English (en)
Slovenian (sl)
Inventor
A. R. C. Murty Bulusu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310969A external-priority patent/GB9310969D0/en
Priority claimed from GB939310975A external-priority patent/GB9310975D0/en
Priority claimed from GB939312590A external-priority patent/GB9312590D0/en
Priority claimed from GB939313553A external-priority patent/GB9313553D0/en
Priority claimed from GB939319618A external-priority patent/GB9319618D0/en
Priority claimed from GB939319617A external-priority patent/GB9319617D0/en
Priority claimed from GB939326045A external-priority patent/GB9326045D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI0626385T1 publication Critical patent/SI0626385T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Color Printing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI9430457T 1993-05-27 1994-05-24 Tetrahydropyran derivatives SI0626385T1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB939310969A GB9310969D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939310975A GB9310975D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939312590A GB9312590D0 (en) 1993-06-18 1993-06-18 Organic compounds
GB939313553A GB9313553D0 (en) 1993-07-01 1993-07-01 Organic compounds
GB939319618A GB9319618D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939319617A GB9319617D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939326045A GB9326045D0 (en) 1993-12-21 1993-12-21 Organic compounds
EP94810297A EP0626385B1 (de) 1993-05-27 1994-05-24 Tetrahydropyran-Derivate

Publications (1)

Publication Number Publication Date
SI0626385T1 true SI0626385T1 (en) 2004-02-29

Family

ID=27562893

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9430457T SI0626385T1 (en) 1993-05-27 1994-05-24 Tetrahydropyran derivatives

Country Status (24)

Country Link
US (1) US5493019A (de)
EP (1) EP0626385B1 (de)
JP (1) JP3076724B2 (de)
CN (1) CN1048495C (de)
AT (1) ATE252105T1 (de)
AU (1) AU682499B2 (de)
CA (1) CA2124260C (de)
CY (1) CY2523B1 (de)
CZ (1) CZ286157B6 (de)
DE (1) DE69433234T2 (de)
DK (1) DK0626385T3 (de)
ES (1) ES2208651T3 (de)
FI (1) FI107159B (de)
HK (1) HK1011684A1 (de)
HU (1) HU218919B (de)
IL (1) IL109775A (de)
MY (1) MY110603A (de)
NO (1) NO308302B1 (de)
NZ (1) NZ260596A (de)
PH (1) PH30420A (de)
PT (1) PT626385E (de)
RU (1) RU2130460C1 (de)
SI (1) SI0626385T1 (de)
SK (1) SK281541B6 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100335063C (zh) 1994-10-26 2007-09-05 诺瓦蒂斯有限公司 药物组合物
AU748334B2 (en) 1997-10-16 2002-05-30 Board Of Regents, The University Of Texas System Models and treatments for cardiac hypertrophy in relation with NF-AT3 function
TR200002771T2 (tr) 1998-03-26 2001-02-21 Fujisawa Pharmaceutical Co.,Ltd. Devamlı salımı olan preparatlar
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
US20060115500A1 (en) 2002-07-23 2006-06-01 Jithan Aukunuru Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
JP2007516951A (ja) * 2003-12-30 2007-06-28 アステラス製薬株式会社 気道閉塞症の治療または予防のためのマクロライドの使用
GT200500282A (es) 2004-10-12 2006-05-04 Heteroatomos conteniendo compuestos triciclicos.
EP1688161A1 (de) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Verwendung von pirlindol zur Behandlung der Krankheiten gekennzeichnet durch Proliferation von t-Lymphozyten und/oder Hyperproliferation von Keratinozyten, ins besondere atopischer Dermatitis und Psoriasis
CA2768210C (en) * 2009-07-15 2017-08-15 S*Bio Pte Ltd 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14,18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt
ES2898849T3 (es) 2014-10-28 2022-03-09 Koushi Yamaguchi Medicamento para mejorar el síndrome de hipertensión inducida por el embarazo
EP3834826A4 (de) 2018-08-10 2022-07-27 Koushi Yamaguchi Therapeutisches mittel für humorale immunitätsbedingte erkrankungen in der materno-fetalen beziehung
WO2020129348A1 (ja) 2018-12-18 2020-06-25 晃史 山口 不妊・不育症または妊娠状態を改善するための薬剤
MX2021008824A (es) * 2019-01-23 2021-10-13 Univ Johns Hopkins Análogos no inmunosupresores de tacrolimus (fk506) y uso de los mismos.
WO2022139524A1 (ko) * 2020-12-24 2022-06-30 서울대학교산학협력단 신규 fk506 유도체 및 이를 포함하는 발모 촉진용 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078235A3 (de) * 1981-10-23 1983-06-29 Ciba-Geigy Ag Dihalogenierte Steroide
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
EP0385936A1 (de) * 1989-02-27 1990-09-05 Ciba-Geigy Ag Peptidlacton und derivate davon, Verfahren zu ihrer Herstellung und Mittel zur Ausführung des Verfahrens
JPH05505798A (ja) * 1990-03-13 1993-08-26 フアイソンズ・ピーエルシー 免疫抑制マクロ環状化合物
CA2051872A1 (en) * 1990-09-24 1992-03-25 Kevin M. Byrne Directed biosynthesis process for prolyl-immunomycin
GB2249787A (en) * 1990-11-19 1992-05-20 Fujisawa Pharmaceutical Co Lactone compounds
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
JP3036923B2 (ja) * 1991-10-28 2000-04-24 理化学研究所 デプシペプチドａ、ｂその製造方法、並びに抗ウイルス剤及び抗菌剤
HUT66531A (en) * 1992-05-07 1994-12-28 Sandoz Ag Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them

Also Published As

Publication number Publication date
DK0626385T3 (da) 2004-02-16
MY110603A (en) 1998-08-29
IL109775A (en) 1999-07-14
HU218919B (hu) 2000-12-28
CN1048495C (zh) 2000-01-19
DE69433234T2 (de) 2004-08-05
HK1011684A1 (en) 1999-07-16
JP3076724B2 (ja) 2000-08-14
FI942444A0 (fi) 1994-05-25
FI107159B (fi) 2001-06-15
AU6331794A (en) 1994-12-01
CA2124260A1 (en) 1994-11-28
NO941936L (no) 1994-11-28
CZ129594A3 (en) 1995-01-18
US5493019A (en) 1996-02-20
ES2208651T3 (es) 2004-06-16
NZ260596A (en) 1995-10-26
NO308302B1 (no) 2000-08-28
RU2130460C1 (ru) 1999-05-20
EP0626385A1 (de) 1994-11-30
PT626385E (pt) 2004-03-31
SK61194A3 (en) 1995-02-08
CA2124260C (en) 2007-04-17
SK281541B6 (sk) 2001-04-09
PH30420A (en) 1997-05-09
IL109775A0 (en) 1994-08-26
HUT71396A (en) 1995-11-28
DE69433234D1 (de) 2003-11-20
JPH06340672A (ja) 1994-12-13
CZ286157B6 (cs) 2000-01-12
CY2523B1 (en) 2006-02-08
FI942444A (fi) 1994-11-28
ATE252105T1 (de) 2003-11-15
NO941936D0 (no) 1994-05-25
EP0626385B1 (de) 2003-10-15
CN1099756A (zh) 1995-03-08
AU682499B2 (en) 1997-10-09
HU9401582D0 (en) 1994-08-29

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