PT626385E - Derivados do tetra-hidropirano - Google Patents

Derivados do tetra-hidropirano

Info

Publication number
PT626385E
PT626385E PT94810297T PT94810297T PT626385E PT 626385 E PT626385 E PT 626385E PT 94810297 T PT94810297 T PT 94810297T PT 94810297 T PT94810297 T PT 94810297T PT 626385 E PT626385 E PT 626385E
Authority
PT
Portugal
Prior art keywords
hydropyrane
tetra
derivatives
hydroxy groups
antiinflammatory
Prior art date
Application number
PT94810297T
Other languages
English (en)
Inventor
A R C Murty Bulusu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310969A external-priority patent/GB9310969D0/en
Priority claimed from GB939310975A external-priority patent/GB9310975D0/en
Priority claimed from GB939312590A external-priority patent/GB9312590D0/en
Priority claimed from GB939313553A external-priority patent/GB9313553D0/en
Priority claimed from GB939319617A external-priority patent/GB9319617D0/en
Priority claimed from GB939319618A external-priority patent/GB9319618D0/en
Priority claimed from GB939326045A external-priority patent/GB9326045D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT626385E publication Critical patent/PT626385E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Color Printing (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT94810297T 1993-05-27 1994-05-24 Derivados do tetra-hidropirano PT626385E (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB939310969A GB9310969D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939310975A GB9310975D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939312590A GB9312590D0 (en) 1993-06-18 1993-06-18 Organic compounds
GB939313553A GB9313553D0 (en) 1993-07-01 1993-07-01 Organic compounds
GB939319617A GB9319617D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939319618A GB9319618D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939326045A GB9326045D0 (en) 1993-12-21 1993-12-21 Organic compounds

Publications (1)

Publication Number Publication Date
PT626385E true PT626385E (pt) 2004-03-31

Family

ID=27562893

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94810297T PT626385E (pt) 1993-05-27 1994-05-24 Derivados do tetra-hidropirano

Country Status (24)

Country Link
US (1) US5493019A (pt)
EP (1) EP0626385B1 (pt)
JP (1) JP3076724B2 (pt)
CN (1) CN1048495C (pt)
AT (1) ATE252105T1 (pt)
AU (1) AU682499B2 (pt)
CA (1) CA2124260C (pt)
CY (1) CY2523B1 (pt)
CZ (1) CZ286157B6 (pt)
DE (1) DE69433234T2 (pt)
DK (1) DK0626385T3 (pt)
ES (1) ES2208651T3 (pt)
FI (1) FI107159B (pt)
HK (1) HK1011684A1 (pt)
HU (1) HU218919B (pt)
IL (1) IL109775A (pt)
MY (1) MY110603A (pt)
NO (1) NO308302B1 (pt)
NZ (1) NZ260596A (pt)
PH (1) PH30420A (pt)
PT (1) PT626385E (pt)
RU (1) RU2130460C1 (pt)
SI (1) SI0626385T1 (pt)
SK (1) SK281541B6 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2308546B (en) 1994-10-26 1999-06-02 Novartis Ag Topical macrolide compositions
JP2001520170A (ja) 1997-10-16 2001-10-30 ボード・オヴ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム Ｎｆ−ａｔ３機能に関連した心肥大動物モデルと治療法
TWI235068B (en) 1998-03-26 2005-07-01 Fujisawa Pharmaceutical Co Sustained-release pharmaceutical composition
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
JP2005536516A (ja) 2002-07-23 2005-12-02 ノバルティス アクチエンゲゼルシャフト 薬剤、軟膏基剤および可溶化剤／分散剤を含む、眼科用軟膏組成物
EP1699456A1 (en) * 2003-12-30 2006-09-13 Astellas Pharma Inc. Use of macrolides for treating or preventing airflow obstruction
GT200500282A (es) 2004-10-12 2006-05-04 Heteroatomos conteniendo compuestos triciclicos.
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
BR112012000750B1 (pt) * 2009-07-15 2021-05-25 Cti Biopharma Corp. sal citrato cristalino, composição farmacêutica compreendendo o referido sal e uso do mesmo
WO2016068208A1 (ja) 2014-10-28 2016-05-06 国立研究開発法人国立成育医療研究センター 妊娠状態を改善するための薬剤及びその利用
CN112533599A (zh) 2018-08-10 2021-03-19 山口晃史 与母体和胎儿的关系中的体液免疫相关的疾病的治疗药
JPWO2020129348A1 (ja) 2018-12-18 2021-11-04 晃史 山口 不妊・不育症または妊娠状態を改善するための薬剤
CA3127613A1 (en) * 2019-01-23 2020-07-30 The Johns Hopkins University Non-immunosuppressive fk506 analogs and use thereof
WO2022139524A1 (ko) * 2020-12-24 2022-06-30 서울대학교산학협력단 신규 fk506 유도체 및 이를 포함하는 발모 촉진용 조성물

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078235A3 (de) * 1981-10-23 1983-06-29 Ciba-Geigy Ag Dihalogenierte Steroide
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
GB2212061B (en) * 1987-11-09 1991-08-28 Sandoz Ltd Topical compositions comprising 11,28-dioxa-4-azatricyclo [22.3.1.0(4,9)] octacos-18-ene derivatives
EP0385936A1 (de) * 1989-02-27 1990-09-05 Ciba-Geigy Ag Peptidlacton und derivate davon, Verfahren zu ihrer Herstellung und Mittel zur Ausführung des Verfahrens
JPH05505798A (ja) * 1990-03-13 1993-08-26 フアイソンズ・ピーエルシー 免疫抑制マクロ環状化合物
CA2051872A1 (en) * 1990-09-24 1992-03-25 Kevin M. Byrne Directed biosynthesis process for prolyl-immunomycin
GB2249787A (en) * 1990-11-19 1992-05-20 Fujisawa Pharmaceutical Co Lactone compounds
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
JP3036923B2 (ja) * 1991-10-28 2000-04-24 理化学研究所 デプシペプチドａ、ｂその製造方法、並びに抗ウイルス剤及び抗菌剤
HUT66531A (en) * 1992-05-07 1994-12-28 Sandoz Ag Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them

Also Published As

Publication number Publication date
IL109775A (en) 1999-07-14
SI0626385T1 (en) 2004-02-29
FI942444A (fi) 1994-11-28
MY110603A (en) 1998-08-29
NO941936L (no) 1994-11-28
US5493019A (en) 1996-02-20
HK1011684A1 (en) 1999-07-16
ATE252105T1 (de) 2003-11-15
EP0626385B1 (en) 2003-10-15
CZ129594A3 (en) 1995-01-18
AU682499B2 (en) 1997-10-09
FI942444A0 (fi) 1994-05-25
NO941936D0 (no) 1994-05-25
HUT71396A (en) 1995-11-28
CA2124260A1 (en) 1994-11-28
NZ260596A (en) 1995-10-26
DK0626385T3 (da) 2004-02-16
AU6331794A (en) 1994-12-01
SK281541B6 (sk) 2001-04-09
IL109775A0 (en) 1994-08-26
CN1099756A (zh) 1995-03-08
CZ286157B6 (cs) 2000-01-12
DE69433234T2 (de) 2004-08-05
DE69433234D1 (de) 2003-11-20
FI107159B (fi) 2001-06-15
PH30420A (en) 1997-05-09
HU9401582D0 (en) 1994-08-29
CN1048495C (zh) 2000-01-19
SK61194A3 (en) 1995-02-08
CA2124260C (en) 2007-04-17
JP3076724B2 (ja) 2000-08-14
JPH06340672A (ja) 1994-12-13
EP0626385A1 (en) 1994-11-30
RU2130460C1 (ru) 1999-05-20
NO308302B1 (no) 2000-08-28
CY2523B1 (en) 2006-02-08
HU218919B (hu) 2000-12-28
ES2208651T3 (es) 2004-06-16

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