SI0626385T1 - Tetrahydropyran derivatives - Google Patents

Tetrahydropyran derivatives

Info

Publication number
SI0626385T1
SI0626385T1 SI9430457T SI9430457T SI0626385T1 SI 0626385 T1 SI0626385 T1 SI 0626385T1 SI 9430457 T SI9430457 T SI 9430457T SI 9430457 T SI9430457 T SI 9430457T SI 0626385 T1 SI0626385 T1 SI 0626385T1
Authority
SI
Slovenia
Prior art keywords
hydroxy groups
antiinflammatory
free
tetrahydropyran derivatives
various
Prior art date
Application number
SI9430457T
Other languages
English (en)
Slovenian (sl)
Inventor
A. R. C. Murty Bulusu
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939310975A external-priority patent/GB9310975D0/en
Priority claimed from GB939310969A external-priority patent/GB9310969D0/en
Priority claimed from GB939312590A external-priority patent/GB9312590D0/en
Priority claimed from GB939313553A external-priority patent/GB9313553D0/en
Priority claimed from GB939319618A external-priority patent/GB9319618D0/en
Priority claimed from GB939319617A external-priority patent/GB9319617D0/en
Priority claimed from GB939326045A external-priority patent/GB9326045D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SI0626385T1 publication Critical patent/SI0626385T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Color Printing (AREA)
  • Seasonings (AREA)
SI9430457T 1993-05-27 1994-05-24 Tetrahydropyran derivatives SI0626385T1 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB939310975A GB9310975D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939310969A GB9310969D0 (en) 1993-05-27 1993-05-27 Organic compounds
GB939312590A GB9312590D0 (en) 1993-06-18 1993-06-18 Organic compounds
GB939313553A GB9313553D0 (en) 1993-07-01 1993-07-01 Organic compounds
GB939319618A GB9319618D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939319617A GB9319617D0 (en) 1993-09-23 1993-09-23 Organic compounds
GB939326045A GB9326045D0 (en) 1993-12-21 1993-12-21 Organic compounds
EP94810297A EP0626385B1 (en) 1993-05-27 1994-05-24 Tetrahydropyran derivatives

Publications (1)

Publication Number Publication Date
SI0626385T1 true SI0626385T1 (en) 2004-02-29

Family

ID=27562893

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9430457T SI0626385T1 (en) 1993-05-27 1994-05-24 Tetrahydropyran derivatives

Country Status (24)

Country Link
US (1) US5493019A (xx)
EP (1) EP0626385B1 (xx)
JP (1) JP3076724B2 (xx)
CN (1) CN1048495C (xx)
AT (1) ATE252105T1 (xx)
AU (1) AU682499B2 (xx)
CA (1) CA2124260C (xx)
CY (1) CY2523B1 (xx)
CZ (1) CZ286157B6 (xx)
DE (1) DE69433234T2 (xx)
DK (1) DK0626385T3 (xx)
ES (1) ES2208651T3 (xx)
FI (1) FI107159B (xx)
HK (1) HK1011684A1 (xx)
HU (1) HU218919B (xx)
IL (1) IL109775A (xx)
MY (1) MY110603A (xx)
NO (1) NO308302B1 (xx)
NZ (1) NZ260596A (xx)
PH (1) PH30420A (xx)
PT (1) PT626385E (xx)
RU (1) RU2130460C1 (xx)
SI (1) SI0626385T1 (xx)
SK (1) SK281541B6 (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1147766T3 (da) 1994-10-26 2005-08-29 Novartis Ag Farmaceutiske sammensætninger
JP2001520170A (ja) 1997-10-16 2001-10-30 ボード・オヴ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム Ｎｆ−ａｔ３機能に関連した心肥大動物モデルと治療法
ATE464900T1 (de) 1998-03-26 2010-05-15 Astellas Pharma Inc Retardpräparat mit makroliden wie tacrolimus
US6307049B1 (en) 1998-09-30 2001-10-23 The Procter & Gamble Co. Heterocyclic 2-substituted ketoamides
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6121257A (en) * 1999-03-31 2000-09-19 Abbott Laboratories Sulfamate containing macrocyclic immunomodulators
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
WO2004009056A1 (en) 2002-07-23 2004-01-29 Novartis Ag Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
JP2007516951A (ja) * 2003-12-30 2007-06-28 アステラス製薬株式会社 気道閉塞症の治療または予防のためのマクロライドの使用
GT200500282A (es) 2004-10-12 2006-05-04 Heteroatomos conteniendo compuestos triciclicos.
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
BR112012000750B1 (pt) * 2009-07-15 2021-05-25 Cti Biopharma Corp. sal citrato cristalino, composição farmacêutica compreendendo o referido sal e uso do mesmo
US10143682B2 (en) 2014-10-28 2018-12-04 Koushi Yamaguchi Medicine for improving state of pregnancy, and use thereof
WO2020032252A1 (ja) 2018-08-10 2020-02-13 晃史 山口 母体と胎児との関係における液性免疫関連疾患の治療薬
JPWO2020129348A1 (ja) 2018-12-18 2021-11-04 晃史 山口 不妊・不育症または妊娠状態を改善するための薬剤
EP3914599A4 (en) * 2019-01-23 2022-10-19 The Johns Hopkins University NON-IMMUNOSUPPRESSIVE ANALOGS OF FK506 AND ASSOCIATED USE
US20230094227A1 (en) * 2020-12-24 2023-03-30 Seoul National University R&Db Foundation Novel fk506 derivative and composition comprising same for promoting hair growth

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0078235A3 (de) * 1981-10-23 1983-06-29 Ciba-Geigy Ag Dihalogenierte Steroide
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DK175235B1 (da) * 1987-11-09 2004-07-19 Novartis Ag Ny anvendelse af azatricycloderivater og farmaceutiske præparater med indhold deraf
EP0385936A1 (de) * 1989-02-27 1990-09-05 Ciba-Geigy Ag Peptidlacton und derivate davon, Verfahren zu ihrer Herstellung und Mittel zur Ausführung des Verfahrens
JPH05505798A (ja) * 1990-03-13 1993-08-26 フアイソンズ・ピーエルシー 免疫抑制マクロ環状化合物
CA2051872A1 (en) * 1990-09-24 1992-03-25 Kevin M. Byrne Directed biosynthesis process for prolyl-immunomycin
GB2249787A (en) * 1990-11-19 1992-05-20 Fujisawa Pharmaceutical Co Lactone compounds
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
JP3036923B2 (ja) * 1991-10-28 2000-04-24 理化学研究所 デプシペプチドａ、ｂその製造方法、並びに抗ウイルス剤及び抗菌剤
HUT66531A (en) * 1992-05-07 1994-12-28 Sandoz Ag Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them

Also Published As

Publication number Publication date
JPH06340672A (ja) 1994-12-13
PH30420A (en) 1997-05-09
HUT71396A (en) 1995-11-28
RU2130460C1 (ru) 1999-05-20
SK281541B6 (sk) 2001-04-09
NO308302B1 (no) 2000-08-28
US5493019A (en) 1996-02-20
CZ129594A3 (en) 1995-01-18
FI107159B (fi) 2001-06-15
DE69433234T2 (de) 2004-08-05
NZ260596A (en) 1995-10-26
DK0626385T3 (da) 2004-02-16
NO941936L (no) 1994-11-28
EP0626385A1 (en) 1994-11-30
IL109775A0 (en) 1994-08-26
CA2124260C (en) 2007-04-17
EP0626385B1 (en) 2003-10-15
NO941936D0 (no) 1994-05-25
HK1011684A1 (en) 1999-07-16
FI942444A0 (fi) 1994-05-25
CZ286157B6 (cs) 2000-01-12
HU218919B (hu) 2000-12-28
FI942444A (fi) 1994-11-28
CN1048495C (zh) 2000-01-19
HU9401582D0 (en) 1994-08-29
JP3076724B2 (ja) 2000-08-14
CA2124260A1 (en) 1994-11-28
PT626385E (pt) 2004-03-31
SK61194A3 (en) 1995-02-08
IL109775A (en) 1999-07-14
AU6331794A (en) 1994-12-01
CN1099756A (zh) 1995-03-08
ES2208651T3 (es) 2004-06-16
DE69433234D1 (de) 2003-11-20
AU682499B2 (en) 1997-10-09
MY110603A (en) 1998-08-29
ATE252105T1 (de) 2003-11-15
CY2523B1 (en) 2006-02-08

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