SG54306A1 - Difluoro pentapeptide derivative anti-inflammatory agents - Google Patents

Difluoro pentapeptide derivative anti-inflammatory agents

Info

Publication number
SG54306A1
SG54306A1 SG1996008179A SG1996008179A SG54306A1 SG 54306 A1 SG54306 A1 SG 54306A1 SG 1996008179 A SG1996008179 A SG 1996008179A SG 1996008179 A SG1996008179 A SG 1996008179A SG 54306 A1 SG54306 A1 SG 54306A1
Authority
SG
Singapore
Prior art keywords
difluoro
inflammatory agents
pentapeptide derivative
derivative anti
pentapeptide
Prior art date
Application number
SG1996008179A
Other languages
English (en)
Inventor
Mciver John Mcmillan
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of SG54306A1 publication Critical patent/SG54306A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG1996008179A 1992-12-22 1993-12-16 Difluoro pentapeptide derivative anti-inflammatory agents SG54306A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99521792A 1992-12-22 1992-12-22

Publications (1)

Publication Number Publication Date
SG54306A1 true SG54306A1 (en) 1998-11-16

Family

ID=25541529

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996008179A SG54306A1 (en) 1992-12-22 1993-12-16 Difluoro pentapeptide derivative anti-inflammatory agents

Country Status (22)

Country Link
US (1) US5760002A (hu)
EP (1) EP0675901A1 (hu)
JP (1) JPH08505143A (hu)
KR (1) KR950704350A (hu)
CN (1) CN1056615C (hu)
AU (1) AU697299B2 (hu)
BR (1) BR9307728A (hu)
CA (1) CA2152267C (hu)
CZ (1) CZ286126B6 (hu)
FI (1) FI953106A (hu)
HU (1) HUT72977A (hu)
IL (1) IL108031A0 (hu)
MX (1) MX9400072A (hu)
NO (1) NO952485L (hu)
NZ (1) NZ259274A (hu)
PE (1) PE5195A1 (hu)
PL (1) PL177914B1 (hu)
RU (1) RU2141971C1 (hu)
SG (1) SG54306A1 (hu)
SK (1) SK82795A3 (hu)
TW (1) TW402607B (hu)
WO (1) WO1994014842A1 (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002845A (ja) * 2001-04-03 2003-01-08 Univ Nihon 哺乳類の硬組織治療用組成物及びその治療方法
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CN103259027A (zh) 2005-04-28 2013-08-21 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
TWI556839B (zh) 2009-05-06 2016-11-11 研究室護膚股份有限公司 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009010B1 (en) * 1978-07-18 1983-03-02 Kabi AB Bradykinin inhibiting tripeptide derivatives, process for their preparation and pharmaceutical preparations containing them
HU177098B (en) * 1979-01-04 1981-07-28 Gyogyszerkutato Intezet Process for producing new peptidyl-n-carboxy-l-arginin-a
JPS5754157A (en) * 1980-09-19 1982-03-31 Nippon Kayaku Co Ltd L-argininal derivative and its preparation
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
JPS5830300B2 (ja) * 1981-11-02 1983-06-28 三菱化学株式会社 トリペプチドおよびその誘導体の製造法
JPS58164563A (ja) * 1982-03-25 1983-09-29 Dai Ichi Pure Chem Co Ltd 新規ペプチドアルデヒド類及びその製造法
GB2124233B (en) * 1982-07-19 1985-09-18 Nat Res Dev Synthetic peptides and their preparation
CS231228B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method
DE3481913D1 (de) * 1983-04-27 1990-05-17 Ici America Inc Prolin-derivate.
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes
US4816449A (en) * 1984-08-09 1989-03-28 Immunetech Pharmaceuticals Immunotherapeutic anti-inflammatory peptide agents
US4845242A (en) * 1987-04-28 1989-07-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
ZA86746B (en) * 1985-02-04 1986-09-24 Merrell Dow Pharma Novel peptidase inhibitors
CH672792A5 (hu) * 1985-02-19 1989-12-29 Sandoz Ag
US5066643A (en) * 1985-02-19 1991-11-19 Sandoz Ltd. Fluorine and chlorine statine or statone containing peptides and method of use
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
DE3683541D1 (de) * 1985-06-07 1992-03-05 Ici America Inc Selektionierte difluorverbindungen.
HU200473B (en) * 1985-11-01 1990-06-28 Pfizer Process for producing polypeptides containing difluorocyclostatine and pharmaceutical compositions comprising same
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
GB8613703D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro peptide compounds
NZ223148A (en) * 1987-01-16 1989-10-27 Merrell Dow Pharma Peptide derivatives having peptidase inhibition activity
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
JPH075634B2 (ja) * 1987-10-30 1995-01-25 日東紡績株式会社 トリペプチド類及びこれを含有する抗プラスミン剤
US4902781A (en) * 1987-11-24 1990-02-20 Taisho Pharmaceutical Co., Ltd. Novel tripetide derivatives
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
YU30589A (en) * 1989-02-09 1991-10-31 Imunoloski Z Zagreb New adamantyl containing tripeptides and it's hydrochloride and process for preparing and use
GB8910547D0 (en) * 1989-05-08 1989-06-21 Ici America Inc Substituted ketones
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues

Also Published As

Publication number Publication date
HUT72977A (en) 1996-06-28
NO952485D0 (no) 1995-06-21
EP0675901A1 (en) 1995-10-11
CZ164595A3 (en) 1995-12-13
CN1056615C (zh) 2000-09-20
PL177914B1 (pl) 2000-01-31
HU9501844D0 (en) 1995-08-28
IL108031A0 (en) 1994-04-12
NO952485L (no) 1995-08-22
FI953106A0 (fi) 1995-06-21
CA2152267A1 (en) 1994-07-07
WO1994014842A1 (en) 1994-07-07
MX9400072A (es) 1994-08-31
JPH08505143A (ja) 1996-06-04
AU5803994A (en) 1994-07-19
CA2152267C (en) 2001-04-17
TW402607B (en) 2000-08-21
PL309638A1 (en) 1995-10-30
KR950704350A (ko) 1995-11-20
CN1095072A (zh) 1994-11-16
PE5195A1 (es) 1995-03-08
SK82795A3 (en) 1995-12-06
BR9307728A (pt) 1999-08-31
US5760002A (en) 1998-06-02
AU697299B2 (en) 1998-10-01
RU95113497A (ru) 1997-06-10
CZ286126B6 (cs) 2000-01-12
RU2141971C1 (ru) 1999-11-27
NZ259274A (en) 1997-10-24
FI953106A (fi) 1995-07-13

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