SG50831A1 - Fluorinated bitamin d3 analogs - Google Patents

Fluorinated bitamin d3 analogs

Info

Publication number
SG50831A1
SG50831A1 SG1997001491A SG1997001491A SG50831A1 SG 50831 A1 SG50831 A1 SG 50831A1 SG 1997001491 A SG1997001491 A SG 1997001491A SG 1997001491 A SG1997001491 A SG 1997001491A SG 50831 A1 SG50831 A1 SG 50831A1
Authority
SG
Singapore
Prior art keywords
bitamin
fluorinated
analogs
fluorinated bitamin
Prior art date
Application number
SG1997001491A
Other languages
English (en)
Inventor
Bernard Michael Hennessy
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG50831A1 publication Critical patent/SG50831A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG1997001491A 1996-05-23 1997-05-12 Fluorinated bitamin d3 analogs SG50831A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1818796P 1996-05-23 1996-05-23

Publications (1)

Publication Number Publication Date
SG50831A1 true SG50831A1 (en) 1998-07-20

Family

ID=21786696

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1997001491A SG50831A1 (en) 1996-05-23 1997-05-12 Fluorinated bitamin d3 analogs

Country Status (30)

Country Link
US (1) US5888994A (zh)
EP (1) EP0808831B1 (zh)
JP (1) JP2858571B2 (zh)
KR (1) KR100237523B1 (zh)
CN (1) CN1081184C (zh)
AR (1) AR007240A1 (zh)
AT (1) ATE195514T1 (zh)
AU (1) AU720098B2 (zh)
BR (1) BR9703373A (zh)
CA (1) CA2204478C (zh)
CO (1) CO4840512A1 (zh)
CZ (1) CZ157997A3 (zh)
DE (1) DE69702812T2 (zh)
DK (1) DK0808831T3 (zh)
ES (1) ES2150719T3 (zh)
GR (1) GR3034832T3 (zh)
HR (1) HRP970274A2 (zh)
HU (1) HUP9700927A3 (zh)
IL (1) IL120842A0 (zh)
MA (1) MA24345A1 (zh)
NO (1) NO971934L (zh)
NZ (1) NZ314838A (zh)
PL (1) PL320131A1 (zh)
PT (1) PT808831E (zh)
SG (1) SG50831A1 (zh)
TR (1) TR199700418A2 (zh)
TW (1) TW374762B (zh)
UY (1) UY24563A1 (zh)
YU (1) YU19997A (zh)
ZA (1) ZA974334B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger
EP0981514B1 (en) * 1997-05-16 2006-04-05 Woman & Infants Hospital 3-epi vitamin d2 compounds and uses thereof
US6100294A (en) * 1997-05-16 2000-08-08 Women And Infants Hospital Cyclic ether vitamin D3 compounds, 1α(OH) 3-epi-vitamin D3 compounds and uses thereof
JP4219553B2 (ja) * 1997-09-08 2009-02-04 エフ．ホフマン−ラ ロシュ アーゲー １，３−ジヒドロキシ−２０，２０−ジアルキル−ビタミンｄ３類似体
AU3390400A (en) * 1999-03-05 2000-09-21 Johns Hopkins University, The Regulating skin appearance and composition with a fluorinated vitamin d3 analog compound
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
JP2008519808A (ja) 2004-11-12 2008-06-12 ビオエクセル エスピーエー 膀胱癌治療のためのビタミンｄ誘導体及び抗増殖薬の併用
CA2882048C (en) 2006-02-03 2020-03-24 Proventiv Therapeutics, Llc Treating vitamin d insufficiency and deficiency with 25-hydroxyvitamin d2 and 25-hydroxyvitamin d3
DK3357496T3 (da) 2006-06-21 2020-05-11 Opko Ireland Global Holdings Ltd Terapi ved brug af vitamin d-repletteringsmiddel og vitamin d-hormonsubstitutionsmiddel
KR101495578B1 (ko) 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
ES2956794T3 (es) 2007-04-25 2023-12-28 Eirgen Pharma Ltd Liberación controlada de 25-hidroxivitamina D
EP3636280A1 (en) 2010-03-29 2020-04-15 Opko Ireland Global Holdings, Ltd. Methods and compositions for reducing parathyroid levels
US8754067B2 (en) 2010-11-12 2014-06-17 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
US10220047B2 (en) 2014-08-07 2019-03-05 Opko Ireland Global Holdings, Ltd. Adjunctive therapy with 25-hydroxyvitamin D and articles therefor
KR20180123100A (ko) 2016-03-28 2018-11-14 옵코 아일랜드 글로벌 홀딩스 리미티드 비타민 d 치료 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5039671A (en) * 1984-12-19 1991-08-13 Hoffmann-La Roche Inc. Trifluorinated-1α,25S-dihydroxy vitamin D3 compounds
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
GB9017890D0 (en) * 1990-08-15 1990-09-26 Leo Pharm Prod Ltd Chemical compounds i
US5206230A (en) * 1991-06-05 1993-04-27 Daikin Industries, Ltd. Fluorine-containing vitamin D3 analogues and pharmaceutical composition containing the same
US5210237A (en) * 1991-08-27 1993-05-11 Daikin Industries, Ltd. Vitamin d3 analogues
US5200536A (en) * 1992-02-10 1993-04-06 Daikin Industries Ltd. Fluorine-containing vitamin D3 analogues
GB9206648D0 (en) * 1992-03-26 1992-05-06 Leo Pharm Prod Ltd Chemical compounds
ES2091515T3 (es) * 1992-05-20 1996-11-01 Hoffmann La Roche Analogos fluorados de la vitamina d3.
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
TW267161B (zh) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
NO971934L (no) * 1996-05-23 1997-11-24 Hoffmann La Roche Flourinerte vitamin D3 -analoger

Also Published As

Publication number Publication date
TW374762B (en) 1999-11-21
NZ314838A (en) 1998-01-26
BR9703373A (pt) 1998-09-15
NO971934D0 (no) 1997-04-25
HUP9700927A2 (hu) 1998-01-28
JPH1045712A (ja) 1998-02-17
UY24563A1 (es) 2000-12-29
CZ157997A3 (en) 1997-12-17
HUP9700927A3 (en) 1999-07-28
PL320131A1 (en) 1997-11-24
DE69702812D1 (de) 2000-09-21
MX9703776A (es) 1998-06-30
DE69702812T2 (de) 2001-01-25
EP0808831A3 (en) 1999-02-03
YU19997A (sh) 1999-07-28
CO4840512A1 (es) 1999-09-27
ZA974334B (en) 1997-11-24
KR970074763A (ko) 1997-12-10
PT808831E (pt) 2000-12-29
EP0808831B1 (en) 2000-08-16
IL120842A0 (en) 1997-09-30
CA2204478C (en) 2006-11-21
HU9700927D0 (en) 1997-07-28
KR100237523B1 (ko) 2000-01-15
HRP970274A2 (en) 1998-04-30
CN1169425A (zh) 1998-01-07
ES2150719T3 (es) 2000-12-01
MA24345A1 (fr) 1998-07-01
JP2858571B2 (ja) 1999-02-17
NO971934L (no) 1997-11-24
DK0808831T3 (da) 2001-01-02
US5888994A (en) 1999-03-30
TR199700418A3 (tr) 1997-12-21
CA2204478A1 (en) 1997-11-23
CN1081184C (zh) 2002-03-20
GR3034832T3 (en) 2001-02-28
AU2357297A (en) 1997-11-27
AU720098B2 (en) 2000-05-25
TR199700418A2 (xx) 1997-12-21
AR007240A1 (es) 1999-10-27
EP0808831A2 (en) 1997-11-26
ATE195514T1 (de) 2000-09-15

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