SG48788A1 - Novel derivatives of y-cyclodextrin - Google Patents

Novel derivatives of y-cyclodextrin

Info

Publication number
SG48788A1
SG48788A1 SG1996001668A SG1996001668A SG48788A1 SG 48788 A1 SG48788 A1 SG 48788A1 SG 1996001668 A SG1996001668 A SG 1996001668A SG 1996001668 A SG1996001668 A SG 1996001668A SG 48788 A1 SG48788 A1 SG 48788A1
Authority
SG
Singapore
Prior art keywords
cyclodextrin
alkyl
novel derivatives
compositions
preparation
Prior art date
Application number
SG1996001668A
Other languages
English (en)
Inventor
Bernd Willi Werner Muller
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG48788A1 publication Critical patent/SG48788A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG1996001668A 1985-03-15 1986-03-04 Novel derivatives of y-cyclodextrin SG48788A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858506792A GB8506792D0 (en) 1985-03-15 1985-03-15 Derivatives of y-cyclodextrin

Publications (1)

Publication Number Publication Date
SG48788A1 true SG48788A1 (en) 1998-05-18

Family

ID=10576063

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996001668A SG48788A1 (en) 1985-03-15 1986-03-04 Novel derivatives of y-cyclodextrin

Country Status (22)

Country Link
US (1) US4764604A (US07446107-20081104-C00009.png)
EP (2) EP0197571B1 (US07446107-20081104-C00009.png)
JP (1) JP2562809B2 (US07446107-20081104-C00009.png)
KR (1) KR930007386B1 (US07446107-20081104-C00009.png)
AT (2) ATE159954T1 (US07446107-20081104-C00009.png)
AU (1) AU583599B2 (US07446107-20081104-C00009.png)
CA (1) CA1300130C (US07446107-20081104-C00009.png)
CY (1) CY1918A (US07446107-20081104-C00009.png)
DE (2) DE3650336T2 (US07446107-20081104-C00009.png)
DK (1) DK176156B1 (US07446107-20081104-C00009.png)
ES (1) ES8705899A1 (US07446107-20081104-C00009.png)
FI (1) FI84076C (US07446107-20081104-C00009.png)
GB (1) GB8506792D0 (US07446107-20081104-C00009.png)
GR (1) GR860685B (US07446107-20081104-C00009.png)
HK (1) HK131896A (US07446107-20081104-C00009.png)
HU (2) HU198092B (US07446107-20081104-C00009.png)
IE (1) IE66673B1 (US07446107-20081104-C00009.png)
NO (1) NO167578C (US07446107-20081104-C00009.png)
NZ (1) NZ215350A (US07446107-20081104-C00009.png)
PT (1) PT82186B (US07446107-20081104-C00009.png)
SG (1) SG48788A1 (US07446107-20081104-C00009.png)
ZA (1) ZA861930B (US07446107-20081104-C00009.png)

Families Citing this family (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6333341A (ja) * 1986-07-28 1988-02-13 Seitetsu Kagaku Co Ltd 配糖体の処理方法
DE3710569A1 (de) * 1986-10-31 1988-05-19 Agency Ind Science Techn Cyclodextrinverbindung, sie verwendender ultraduenner film und verfahren zur herstellung
JPS63117003A (ja) * 1986-10-31 1988-05-21 Agency Of Ind Science & Technol シクロデキストリン誘導体
JPH0819004B2 (ja) * 1986-12-26 1996-02-28 日清製粉株式会社 徐放性医薬製剤
IT1203968B (it) * 1987-04-24 1989-02-23 Bononi Ricerca Complessi di b-ciclodestrina ad attivita' antimicotica
NZ224497A (en) * 1987-05-18 1990-04-26 Janssen Pharmaceutica Nv Pharmaceutical composition comprising flunarizine
NZ225045A (en) * 1987-07-01 1990-06-26 Janssen Pharmaceutica Nv Antiviral pharmaceutical compositions containing cyclodextrin and an antiviral agent
US5002935A (en) * 1987-12-30 1991-03-26 University Of Florida Improvements in redox systems for brain-targeted drug delivery
US5017566A (en) * 1987-12-30 1991-05-21 University Of Florida Redox systems for brain-targeted drug delivery
US5658894A (en) * 1989-04-23 1997-08-19 The Trustees Of The University Of Pennsylvania Compositions for inhibiting restenosis
US5760015A (en) * 1988-01-19 1998-06-02 The Trustees Of The University Of Pennsylvania Cyclodextrin compounds and methods of making and use thereof
IE64346B1 (en) * 1988-01-19 1995-07-26 Moses Judah Folkman Growth inhibiting agent and the use thereof
US5637575A (en) * 1988-01-19 1997-06-10 The Trustees Of The University Of Pennsylvania Methods of inhibiting restenosis
US5183809A (en) * 1990-02-15 1993-02-02 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Cyclodextrin polymers and cyclodextrins immobilized on a solid surface
US5236944A (en) * 1988-03-28 1993-08-17 Janssen Pharmaceutica N.V. Compounds, compositions and anti-neoplastic methods
WO1989010739A1 (en) * 1988-05-11 1989-11-16 Board Of Regents, The University Of Texas System Hydroxyalkyl cyclodextrin-antifungal polyene antibiotics complexes
US5997856A (en) * 1988-10-05 1999-12-07 Chiron Corporation Method and compositions for solubilization and stabilization of polypeptides, especially proteins
AU616571B2 (en) * 1988-10-28 1991-10-31 Shiseido Company Ltd. Cosmetic composition containing inclusion product with hydroxyalkylated cyclodextrin
US5068227A (en) * 1989-01-18 1991-11-26 Cyclex, Inc. Cyclodextrins as carriers
US5096893A (en) * 1989-04-03 1992-03-17 The United States Of America As Represented By The Department Of Health And Human Services Regioselective substitutions in cyclodextrins
ES2116982T3 (es) * 1989-04-03 1998-08-01 Janssen Pharmaceutica Nv Sustituciones regioselectivas en ciclodextrinas.
US5441944A (en) * 1989-04-23 1995-08-15 The Trustees Of The University Of Pennsylvania Substituted cyclodextrin sulfates and their uses as growth modulating agents
FR2647343B1 (fr) * 1989-05-24 1994-05-06 Rhone Poulenc Sante Nouvelle forme pharmaceutique poreuse et sa preparation
AU5594190A (en) * 1989-06-02 1990-12-06 Ciba-Geigy Ag Intravenous solutions with a rapid onset of action
SE8902235D0 (sv) * 1989-06-20 1989-06-20 Haessle Ab Novel cyclodextrin inclusion complexes
US5064944A (en) * 1989-09-12 1991-11-12 Advanced Separation Technologies Inc. Chiral separation media
US5154738A (en) * 1989-09-12 1992-10-13 Advanced Separation Technologies, Inc. Chiral separation media
EP0491812A4 (en) * 1989-09-14 1992-11-04 Australian Commercial Research & Development Limited Drug delivery compositions
EP0435826A1 (de) * 1989-12-27 1991-07-03 Ciba-Geigy Ag Intravenöse Lösungen für Status Epilepticus
KR0166088B1 (ko) * 1990-01-23 1999-01-15 . 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
HU210921B (en) * 1990-03-28 1995-09-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing inclusion complexes of n-ethoxycarbonyl-3-morpholino-sydnonimine formed with cyclodextrines and pharmaceutical compositions containing them
HU211648A9 (en) * 1990-03-28 1995-12-28 Chinoin Gyogyszer Es Vegyeszet Inclusion complexes of 3-morpholino-sydnonimine or its salts or its tautomer isomer, process for the preparation thereof, and pharmaceutical compositions containing the same
KR927003645A (ko) * 1990-05-21 1992-12-18 후지다 히로미찌 씨클로덱스트린 유도체
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
JP2711759B2 (ja) * 1990-10-24 1998-02-10 エスエス製薬 株式会社 止瀉剤組成物
CA2061891A1 (en) * 1991-03-08 1992-09-09 Robert F. Van Ginckel Flunarizine containing anti-neoplastic compositions
US5446030A (en) * 1991-09-19 1995-08-29 Weisz; Paul B. Prevention of hemolysis
US5231089A (en) * 1991-12-02 1993-07-27 University Of Florida Method of improving oral bioavailability of carbamazepine
JPH05262764A (ja) * 1992-01-24 1993-10-12 Morishita Roussel Kk 1−アリール−2−(1h−1,2,4−トリアゾー ル−1−イル)エタノール誘導体
US5300280A (en) * 1992-02-14 1994-04-05 Mallinckrodt Medical, Inc. Stabilized radiopharmaceutical kits
NZ249494A (en) * 1992-03-18 1996-04-26 Janssen Pharmaceutica Nv Itraconazole and saperconazole stereoisomers; pharmaceutical compositions
FR2693728B1 (fr) * 1992-07-17 1994-09-23 Orsan Procédé de fabrication de cyclodextrines partiellement méthylées et composés obtenus.
US5494901A (en) * 1993-01-05 1996-02-27 Javitt; Jonathan C. Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent
RU2143896C1 (ru) * 1993-03-05 2000-01-10 Хексаль Аг Кристаллический комплекс циклодекстрина с гидрохлоридом ранитидина, способ его получения и содержащие его фармацевтические составы
US6346518B1 (en) 1993-03-10 2002-02-12 Janssen Pharmaceutica N.V. Itraconazole and saperconazole stereoisomers
WO1994022455A1 (en) * 1993-03-31 1994-10-13 The Trustees Of The University Of Pennsylvania Methods of affecting the growth of living tissue in mammals and compounds and compositions therefor
TW349870B (en) * 1993-09-30 1999-01-11 Janssen Pharmaceutica Nv An antifungal pharmaceutical composition for oral administration and a process for the preparation thereof
DE4333598A1 (de) * 1993-10-01 1995-04-06 Consortium Elektrochem Ind Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten, nach dem Verfahren herstellbare methylierte Cyclodextrin-Derivate und die Verwendung der Produkte
RU2135176C1 (ru) * 1993-12-14 1999-08-27 Эли Лилли Энд Компани Водорастворенный комплекс включения соединений бензотиофена с водорастворимым циклодекстрином, способ его получения и фармацевтическая композиция
DE4414138A1 (de) * 1994-04-22 1995-10-26 Consortium Elektrochem Ind Acylierte gamma-Cyclodextrine
TW438601B (en) * 1994-05-18 2001-06-07 Janssen Pharmaceutica Nv New mucoadhesive emulsion compositions and a process for the preparation thereof
DE4428654A1 (de) * 1994-08-12 1996-02-15 Consortium Elektrochem Ind Wasserlösliche Cyclodextrinderivate mit lipophilen Substituenten und Verfahren zu ihrer Herstellung
US5679573A (en) * 1995-07-27 1997-10-21 Abbott Laboratories Stabilized aqueous steroid immunoassay standards with cyclodextrins
US5681828A (en) * 1995-12-19 1997-10-28 Pitha; Josef Selective alkylations of cyclodextrins leading to derivatives which have a rigidly extended cavity
US5935941A (en) * 1997-10-24 1999-08-10 Pitha; Josef Alkylations of cyclodextrins leading to derivatives which have a ridgidly extended cavity
ATE341317T1 (de) * 1996-03-29 2006-10-15 Ortho Mcneil Pharm Inc Amidinohydrazone als protease-inhibitoren
ATE298582T1 (de) 1996-04-19 2005-07-15 Alpha Therapeutic Corp Verfahren zur inaktivierung von viren und lyophilisierung von blutproteinen
EP0838225A3 (en) * 1996-10-25 1999-03-24 Hiji, Yasutake Aqueous local anesthetic solution
US5916883A (en) * 1996-11-01 1999-06-29 Poly-Med, Inc. Acylated cyclodextrin derivatives
SI0969821T1 (en) * 1997-03-26 2003-10-31 Janssen Pharmaceutica N.V. Pellets having a core coated with an antifungal and a polymer
US5874418A (en) * 1997-05-05 1999-02-23 Cydex, Inc. Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use
KR19990001564A (ko) * 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
ES2185238T3 (es) 1997-12-31 2003-04-16 Choongwae Pharma Corp Preparado oral de itraconazol y su procedimiento de preparacion.
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
US6344486B1 (en) 1998-04-03 2002-02-05 3-Dimensional Pharmaceuticals, Inc. Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors
IL139162A0 (en) 1998-04-24 2001-11-25 Dimensional Pharm Inc Amidinohydrazone, alkoxyguanidine and aminoguanidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
US7091192B1 (en) * 1998-07-01 2006-08-15 California Institute Of Technology Linear cyclodextrin copolymers
AR020650A1 (es) * 1998-08-10 2002-05-22 Poly Med Inc Polimeros fosforilados y conjugados de los mismos
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6194395B1 (en) 1999-02-25 2001-02-27 Orthro-Mcneil Pharmaceutical, Inc. Cyclodextrin cladribine formulations
CA2362728C (en) 1999-03-24 2009-06-23 Fmc Corporation Improved aqueous solubility pharmaceutical formulations
EP1189901A1 (en) 1999-05-27 2002-03-27 3-Dimensional Pharmaceuticals, Inc. Oxazaheterocycles as protease inhibitors
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
DE19930553A1 (de) * 1999-07-02 2001-01-11 Wacker Chemie Gmbh Verfahren zur Herstellung von alkylierten Cyclodextrin-Derivaten
US6420397B1 (en) 1999-07-09 2002-07-16 3-Dimensional Pharmaceuticals, Inc. Heteroaryl protease inhibitors and diagnostic imaging agents
US8614291B2 (en) * 1999-08-10 2013-12-24 Poly-Med, Inc. Phosphorylated polymers and conjugates thereof
ATE253558T1 (de) * 1999-09-13 2003-11-15 Dimensional Pharm Inc Azazykloalkanone serin-protease-hemmer
US6784165B1 (en) * 1999-11-23 2004-08-31 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with N6-substituted-5′-(N-substituted) carboxamidoadenosines
TWI242015B (en) 1999-11-29 2005-10-21 Akzo Nobel Nv 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block
FR2808691B1 (fr) 2000-05-12 2005-06-24 Coletica Cyclodextrines substituees preferentiellement sur leur face primaire par des fonctions acide ou amine
WO2001087360A2 (en) * 2000-05-15 2001-11-22 The Procter & Gamble Company Compositions comprising cyclodextrin derivatives
EP1303510A2 (en) * 2000-07-17 2003-04-23 3-Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine pyrazinones as protease inhibitors
US6635637B2 (en) 2000-08-04 2003-10-21 Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine protease inhibitors
TR200300731T2 (tr) 2000-11-28 2004-08-23 Fmc Corporation Yenebilir PGA kaplama bileşimi
US20020146409A1 (en) * 2001-01-30 2002-10-10 Herring Steven W. Methods for stabilizing lyophilized blood proteins
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US7446107B2 (en) * 2002-02-15 2008-11-04 Transform Pharmaceuticals, Inc. Crystalline forms of conazoles and methods of making and using the same
US20050025791A1 (en) * 2002-06-21 2005-02-03 Julius Remenar Pharmaceutical compositions with improved dissolution
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
JP4906233B2 (ja) * 2002-03-01 2012-03-28 ユニバーシティー オブ サウス フロリダ 少なくとも1種の有効薬剤成分を含有する多構成要素固相
JP2005538953A (ja) * 2002-05-28 2005-12-22 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド 新規チオフェンアミジン、それらの組成物、および補体媒介疾患および病気を治療する方法
US6828311B2 (en) 2002-05-29 2004-12-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Formulation for the parenteral application of a sodium channel blocker
US20070059356A1 (en) * 2002-05-31 2007-03-15 Almarsson Oern Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
AU2003243354A1 (en) * 2002-05-31 2003-12-19 Transform Pharmaceuticals, Inc. Novel conazole crystalline forms and related processes, pharmaceutical compositions and methods
PT1534340E (pt) 2002-09-06 2012-03-13 Cerulean Pharma Inc Polímeros à base de ciclodextrina para a administração de medicamentos ligados por ligação covalente
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
EP1594512A4 (en) * 2003-02-11 2007-07-11 Kemia Inc COMPOUNDS FOR THE TREATMENT OF VIRUS INFECTIONS
CA2520522C (en) * 2003-03-28 2012-05-29 Ivax Corporation Cladribine formulations for improved oral and transmucosal delivery
BR122018068797B1 (pt) * 2003-03-28 2021-04-27 Ares Trading S.A. Composições farmacêuticas de complexo de ciclodextrina-cladribina complexo, usos do referido complexo, bem como processos para a sua preparação
US7550474B2 (en) 2003-04-10 2009-06-23 Johnson & Johnson Pharmaceuticals Research & Development, L.L.C. Substituted phenyl acetamides and their use as protease inhibitors
CA2523746A1 (en) * 2003-04-24 2004-11-25 Aderis Pharmaceuticals, Inc. Method of treating atrial fibrillation or atrial flutter
UA81305C2 (en) 2003-07-02 2007-12-25 Ares Trading Sa Formulation of cladribine (variants), cladribine-cyclodextrin complex, use of cladribine-cyclodextrin complex, mixture
EP1648386A2 (en) * 2003-07-31 2006-04-26 Ivax Corporation Transmucosal dosage forms for brain-targeted steroid chemical delivery systems
US7504401B2 (en) * 2003-08-29 2009-03-17 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
DE10344967B4 (de) * 2003-09-07 2011-07-28 Henkel AG & Co. KGaA, 40589 Alkoxylgruppen-haltige Cyclodextrin-Derivate; Verfahren zu deren Herstellung und deren Verwendung
WO2005025545A2 (en) * 2003-09-17 2005-03-24 Aderis Pharmaceuticals, Inc. Pharmaceutical formulation for controlled release of selodenoson
RU2392004C2 (ru) 2003-09-22 2010-06-20 Бакстер Интернэшнл Инк. Стерилизация под высоким давлением для заключительной стерилизации фармацевтических препаратов и медицинских изделий
CN1294912C (zh) * 2004-03-01 2007-01-17 上海医药工业研究院 伊曲康唑盐酸盐组合物及其冻干粉针
US7829584B2 (en) * 2006-03-21 2010-11-09 Janssen Pharmaceutica Nv Pyridines and pyridine N-oxides as modulators of thrombin
AU2007230716B2 (en) 2006-03-28 2012-05-03 Javelin Pharmaceuticals, Inc. Formulations of low dose diclofenac and beta-cyclodextrin
MX2008012496A (es) 2006-03-28 2009-01-07 Javelin Pharmaceuticals Inc Formulaciones de farmacos anti-inflamatorios no esteroidales de baja dosis y beta-ciclodextrina.
US20080280891A1 (en) * 2006-06-27 2008-11-13 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
EP2046343B1 (en) 2006-07-28 2014-05-14 Onconova Therapeutics, Inc. Formulations of radioprotective alpha, beta unsaturated aryl sulfones
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス, インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
US8653258B2 (en) 2007-06-08 2014-02-18 Georgia State University Research Foundation, Inc. Compositions for regulating or modulating quorum sensing in bacteria, methods of using the compounds, and methods of regulating or modulating quorum sensing in bacteria
JP5048398B2 (ja) * 2007-06-13 2012-10-17 大蔵製薬株式会社 抗真菌剤の医薬組成物
US8845627B2 (en) 2008-08-22 2014-09-30 Boston Scientific Scimed, Inc. Regulating pressure to lower temperature in a cryotherapy balloon catheter
EP2194429A1 (en) * 2008-12-02 2010-06-09 Eastman Kodak Company Gumming compositions with nano-particles for improving scratch sensitivity in image and non-image areas of lithographic printing plates
JP6220126B2 (ja) * 2009-11-23 2017-10-25 セルリアン・ファーマ・インコーポレイテッド 治療的送達のためのシクロデキストリンに基づく重合体
US20140221490A1 (en) 2011-07-20 2014-08-07 Hospira, Inc. Methods of treating pain
CN102499909B (zh) * 2011-12-27 2013-08-07 哈尔滨三联药业有限公司 伊曲康唑分散片及其制备方法
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459731A (en) * 1966-12-16 1969-08-05 Corn Products Co Cyclodextrin polyethers and their production
US4371673A (en) 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
JPS57106698A (en) * 1980-12-22 1982-07-02 Kyowa Hakko Kogyo Co Ltd Easily absorbable map composition and preparation containing the same
JPS58173102A (ja) * 1982-04-06 1983-10-12 Teijin Ltd エ−テル化サイクロデキストリンの単離精製法
HU191101B (en) * 1983-02-14 1987-01-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups
US4596795A (en) * 1984-04-25 1986-06-24 The United States Of America As Represented By The Secretary, Dept. Of Health & Human Services Administration of sex hormones in the form of hydrophilic cyclodextrin derivatives
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives

Also Published As

Publication number Publication date
HK131896A (en) 1996-07-26
ATE159954T1 (de) 1997-11-15
NZ215350A (en) 1989-03-29
FI84076B (fi) 1991-06-28
IE66673B1 (en) 1996-01-24
DE3650336T2 (de) 1995-11-02
IE860685L (en) 1986-09-15
FI84076C (fi) 1991-10-10
JP2562809B2 (ja) 1996-12-11
EP0197571B1 (en) 1995-06-21
EP0197571A3 (en) 1987-09-30
FI861064A (fi) 1986-09-16
ES552984A0 (es) 1987-05-16
PT82186B (pt) 1988-04-21
DK121486A (da) 1986-09-16
DK121486D0 (da) 1986-03-14
NO860971L (no) 1986-09-16
NO167578C (no) 1991-11-20
GR860685B (en) 1986-07-11
HU198092B (en) 1989-07-28
US4764604A (en) 1988-08-16
DE3650655D1 (de) 1997-12-11
AU5476086A (en) 1986-10-16
EP0636634B1 (en) 1997-11-05
GB8506792D0 (en) 1985-04-17
PT82186A (en) 1986-04-01
HUT42514A (en) 1987-07-28
KR930007386B1 (ko) 1993-08-09
EP0636634A1 (en) 1995-02-01
DK176156B1 (da) 2006-10-23
NO167578B (no) 1991-08-12
ES8705899A1 (es) 1987-05-16
CY1918A (en) 1997-03-07
ATE124055T1 (de) 1995-07-15
CA1300130C (en) 1992-05-05
DE3650336D1 (de) 1995-07-27
DE3650655T2 (de) 1998-03-12
US4764604B1 (US07446107-20081104-C00009.png) 1990-06-12
JPS61275301A (ja) 1986-12-05
HU206381B (en) 1992-10-28
EP0197571A2 (en) 1986-10-15
FI861064A0 (fi) 1986-03-14
KR860009032A (ko) 1986-12-19
ZA861930B (en) 1987-10-28
AU583599B2 (en) 1989-05-04

Similar Documents

Publication Publication Date Title
US4764604B1 (US07446107-20081104-C00009.png)
EP0214647A3 (en) Inclusion complexes of 7-isopropoxy-isoflavone and cyclodextrins, process for their preparation and pharmaceutical preparations containing these complexes
IE820136L (en) Pharmaceutical formulation
AU7567787A (en) Taxol derivatives, their preparation and pharmaceutical compositions containing them
CA2091360A1 (en) Mometasone furoate monohydrate, process for making same and pharmaceutical compositions
EP0326196A3 (en) Aqueous pharmaceutical preparation
CA2294783A1 (fr) Compositions pharmaceutiques administrables par voie orale, comprenant une substance active et une cyclodextrine
AU4931985A (en) Pharmaceutical compositions of 1, 1-cyclobutane- dicarboxylatediammineplatinum (ii) and alpha-cyclodextrin
AU2293488A (en) Alkadiene derivatives, their preparation, and pharmaceutical compositions containing them
IL99471A0 (en) Pharmaceutical compositions containing pyridylmethylsulphinyl-1h-benzimidazole derivatives as active ingredient therein
CA2036337A1 (fr) Derives de la 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
SE8503447L (sv) Farmaceutiska och kosmetiska kompositioner, innehallande dihydroxi-1,8-fenyl-10-antron-9 som verksam bestandsdel, samt sett att framstella den verksamma foreningen
BG104452A (en) New derivatives of the methylenebisphosphonic acid
TW228524B (US07446107-20081104-C00009.png)
AU5994696A (en) Modified alpha-d-glcp-(1-2)-alpha-d-glcp-(1-3)-alpha-d-glcp- analogues
ZA867568B (en) Derivatives of thiochroman, its preparation and the pharmaceutical compositions containing it
AU536069B2 (en) An 1,4-dhydropyridine derivative, its preparation and pharmaceutical compositions containing it