SG43009A1 - Stem cell factor - Google Patents

Stem cell factor

Info

Publication number
SG43009A1
SG43009A1 SG1996002213A SG1996002213A SG43009A1 SG 43009 A1 SG43009 A1 SG 43009A1 SG 1996002213 A SG1996002213 A SG 1996002213A SG 1996002213 A SG1996002213 A SG 1996002213A SG 43009 A1 SG43009 A1 SG 43009A1
Authority
SG
Singapore
Prior art keywords
scf
dna sequence
stem cell
cell factor
biological activity
Prior art date
Application number
SG1996002213A
Other languages
English (en)
Inventor
Kristina M Zsebo
Sidney Vaughn Suggs
Robert A Bosselman
Francis Hall Martin
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1990/005548 external-priority patent/WO1991005795A1/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG43009A1 publication Critical patent/SG43009A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hall/Mr Elements (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SG1996002213A 1989-10-16 1990-10-04 Stem cell factor SG43009A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42238389A 1989-10-16 1989-10-16
US53719890A 1990-06-11 1990-06-11
US57361690A 1990-08-24 1990-08-24
PCT/US1990/005548 WO1991005795A1 (en) 1989-10-16 1990-09-28 Stem cell factor
US58970190A 1990-10-01 1990-10-01

Publications (1)

Publication Number Publication Date
SG43009A1 true SG43009A1 (en) 1997-10-17

Family

ID=27503703

Family Applications (2)

Application Number Title Priority Date Filing Date
SG1996002213A SG43009A1 (en) 1989-10-16 1990-10-04 Stem cell factor
SG1996001817A SG59931A1 (en) 1989-10-16 1990-10-04 Stem cell factor

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG1996001817A SG59931A1 (en) 1989-10-16 1990-10-04 Stem cell factor

Country Status (11)

Country Link
US (3) US6218148B1 (xx)
EP (4) EP0992579B1 (xx)
CN (2) CN1289526C (xx)
AT (2) ATE403713T1 (xx)
CZ (3) CZ286303B6 (xx)
DE (2) DE69034258D1 (xx)
DK (1) DK0423980T3 (xx)
GR (1) GR3034559T3 (xx)
HK (1) HK1010397A1 (xx)
SG (2) SG43009A1 (xx)
SK (2) SK98199A3 (xx)

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US5767074A (en) * 1990-08-27 1998-06-16 Sloan-Kettering Institute For Cancer Research Compositions of soluble C-kit ligand and hematopoietic factors
US20030125519A1 (en) 1990-08-27 2003-07-03 Peter Besmer Ligand for the c-kit receptor and methods of use thereof
US20050276784A1 (en) * 1990-08-27 2005-12-15 Solan-Kettering Institute For Cancer Research Ligand for the c-kit receptor and methods of use thereof
DE4224050A1 (de) * 1991-07-31 1993-02-04 Hoffmann La Roche Loesliche kit-liganden
EP1127577A3 (en) * 1992-04-23 2002-11-27 Sloan-Kettering Institute For Cancer Research Ligand for the c-kit receptor and methods of use thereof
US6001803A (en) * 1992-04-23 1999-12-14 Sloan-Kettering Institute For Cancer Research Composition of c-kit ligand, GM-CSF, and TNF-α and method of use
US6288030B1 (en) 1993-12-22 2001-09-11 Amgen Inc. Stem cell factor formulations and methods
US5525708A (en) * 1994-03-28 1996-06-11 Cytomed, Inc. Covalent dimer of kit ligand
IL115825A (en) * 1994-11-04 2006-07-05 Serono Lab Human stem cell factor (scf) protein, dna sequences coding for this protein and pharmaceutical compositions comprising such a protein
US5824789A (en) * 1995-06-07 1998-10-20 Systemix, Inc. Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof
US6184200B1 (en) 1995-09-28 2001-02-06 Amgen Inc. Truncated glial cell line-derived neurotrophic factor
US5731284A (en) * 1995-09-28 1998-03-24 Amgen Inc. Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product
WO1997012633A1 (en) 1995-10-04 1997-04-10 Immunex Corporation Dendritic cell stimulatory factor
US5641750A (en) * 1995-11-29 1997-06-24 Amgen Inc. Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product
US5641749A (en) * 1995-11-29 1997-06-24 Amgen Inc. Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product
US5741778A (en) * 1996-03-19 1998-04-21 Amgen Inc. Method for treating Huntington's disease using glial cell line-derived neurotrophic factor (GDNF) protein product
US5885962A (en) * 1996-04-05 1999-03-23 Amgen Inc. Stem cell factor analog compositions and method
EP0953354A4 (en) * 1996-08-13 2002-10-23 Fujisawa Pharmaceutical Co HEMATOPOIETIC STEM CELLS PROLIFERING ACTIVE SUBSTANCES
US5969105A (en) * 1996-10-25 1999-10-19 Feng; Yiqing Stem cell factor receptor agonists
US6967092B1 (en) 1996-10-25 2005-11-22 Mc Kearn John P Multi-functional chimeric hematopoietic receptor agonists
JPH10158188A (ja) * 1996-11-29 1998-06-16 Senju Pharmaceut Co Ltd 角膜治療用組成物
ATE480558T1 (de) * 1999-12-23 2010-09-15 Univ Geneve Auf scf peptid basiertes basolaterales sortiersignal und inhibitoren dafür
US7767197B2 (en) 2000-06-22 2010-08-03 Endo Pharmaceuticals Colorado LLC Delivery vehicle composition and methods for delivering antigens and other drugs
AU2001273041A1 (en) * 2000-06-26 2002-01-08 Board Of Regents Of The University Of Nebraska Methods for use of delivery composition for expanding, activating, committing ormobilizing one or more pluripotent, self-renewing and committed stem cells
WO2002102432A1 (en) * 2001-06-15 2002-12-27 Johns Hopkins Singapore Pte Ltd Biofunctional fibers
US20030124091A1 (en) * 2001-10-26 2003-07-03 Large Scale Biology Corporation Endothelial cell derived hematopoietic growth factor
US7741098B2 (en) * 2001-11-27 2010-06-22 Nexyte Ab Production of eukaryotic proteins and nucleic acid molecules in C. elegans
AU2003208524A1 (en) 2003-02-14 2004-09-06 Istituto Superiore Di Sanita Stem cell factor for preventing chemotherapy-induced depletion of blood cells
CN100345971C (zh) * 2003-07-14 2007-10-31 第二军医大学免疫学研究所 重组人干细胞因子的原核表达载体、工程菌及制备方法
ES2616337T3 (es) 2003-12-12 2017-06-12 Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1
EP1778865A1 (en) * 2004-06-23 2007-05-02 Epigenomics AG Methods and nucleic acids for the detection of metastasis of colon cell proliferative disorders
CN1993460A (zh) * 2004-07-12 2007-07-04 索林集团意大利有限公司 用于培养人细胞的装置和方法
ATE544463T1 (de) 2004-11-05 2012-02-15 Univ Northwestern Verwendung von scf und g-scf bei der behandlung von hirnischämie und neurologischen störungen
KR20080031684A (ko) 2005-06-14 2008-04-10 암젠 인코포레이티드 자가 - 완충성 단백질 제형
WO2007037795A2 (en) * 2005-08-05 2007-04-05 Amgen Inc. Stable aqueous protein or antibody pharmaceutical formulations and their preparation
AU2006315601A1 (en) * 2005-11-14 2007-05-24 Enterprise Partners Venture Capital Stem cell factor therapy for tissue injury
WO2007102814A2 (en) * 2006-03-07 2007-09-13 Regenetech, Inc. Recombinant mammalian molecules and method for production thereof
WO2007109583A2 (en) 2006-03-17 2007-09-27 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject
CN102626517B (zh) * 2006-03-24 2015-07-29 儿童医疗中心有限公司 调节造血干细胞生长的方法
US20100196336A1 (en) 2006-05-23 2010-08-05 Dongsu Park Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
EP1872790A1 (en) 2006-06-26 2008-01-02 DeveloGen Aktiengesellschaft New formulation for increasing bioavailability of neurturin
AU2007329725B2 (en) * 2006-10-20 2013-05-23 Children's Medical Center Corporation Method to enhance tissue regeneration
KR101643514B1 (ko) 2007-07-09 2016-07-27 제넨테크, 인크. 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지
US20110206781A1 (en) * 2008-05-28 2011-08-25 Zon Leonard I Method to modulate hematopoietic stem cell growth
JP6055165B2 (ja) 2008-11-14 2016-12-27 株式会社Ｉｄファーマ 樹状細胞の製造方法
US9051548B2 (en) 2009-02-03 2015-06-09 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
US9056085B2 (en) 2009-02-03 2015-06-16 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
GB2559498B (en) * 2011-01-10 2018-10-24 Univ Michigan Regents Stem cell factor inhibitor
US20150018408A1 (en) 2013-07-10 2015-01-15 The Regents Of The University Of Michigan Therapeutic antibodies and uses thereof
JP6220791B2 (ja) 2011-12-02 2017-10-25 フェイト セラピューティクス，インコーポレイテッド 増強された幹細胞組成物
ES2682255T3 (es) 2011-12-02 2018-09-19 Fate Therapeutics, Inc. Métodos mejorados de tratamiento de isquemia
EP2968416A4 (en) 2013-03-15 2016-08-17 Fate Therapeutics Inc BIOLOGICAL ACTIVITY TESTING OF CELLS FOR A THERAPEUTIC POTENTIAL
US9889451B2 (en) 2013-08-16 2018-02-13 ADA-ES, Inc. Method to reduce mercury, acid gas, and particulate emissions
LT6161B (lt) 2013-09-27 2015-06-25 Uab Profarma Granuliocitų kolonijas stimuliuojančio faktoriaus sulieti baltymai su kitais augimo faktoriais, optimaliai su kamieninių ląstelių faktoriumi, ir jų gavimo būdas
JP6383216B2 (ja) * 2014-08-08 2018-08-29 シスメックス株式会社 血液分析方法、血液分析装置およびプログラム
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
CN105985424B (zh) * 2015-01-30 2019-08-23 苏州方舟生物医药有限公司 一种干细胞因子功能性肽段及其应用
CN105749252A (zh) * 2016-04-29 2016-07-13 南方医科大学 Il-9作为治疗血小板缺少症的药物的应用
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
CN108541660A (zh) * 2018-04-24 2018-09-18 上海动物园 动物饲养方法、动物饲养装置及其发酵床
WO2020046985A1 (en) * 2018-08-27 2020-03-05 North Carolina State University Targeting kit with splice switching oligonucleotides to induce apoptosis of mast cells

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US4695542A (en) * 1983-10-04 1987-09-22 Dnax Research Institute Of Molecular And Cellular Biology, Inc. cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity
US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
JPS62223126A (ja) 1986-03-25 1987-10-01 Sankyo Co Ltd 血液幹細胞成長因子
US4959455A (en) 1986-07-14 1990-09-25 Genetics Institute, Inc. Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
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Also Published As

Publication number Publication date
EP1241258A2 (en) 2002-09-18
CZ49197A3 (cs) 2000-01-12
SK281487B6 (sk) 2001-04-09
EP1241258A3 (en) 2003-12-10
ATE403713T1 (de) 2008-08-15
US6207417B1 (en) 2001-03-27
EP0676470A1 (en) 1995-10-11
EP0992579B1 (en) 2008-08-06
CZ286305B6 (cs) 2000-03-15
DE69033584D1 (de) 2000-08-17
GR3034559T3 (en) 2001-01-31
HK1010397A1 (en) 1999-06-17
EP0992579A1 (en) 2000-04-12
ATE194651T1 (de) 2000-07-15
CZ286304B6 (cs) 2000-03-15
SG59931A1 (en) 1999-02-22
CN1306007A (zh) 2001-08-01
SK98199A3 (en) 2001-04-09
DK0423980T3 (da) 2000-10-09
US6218148B1 (en) 2001-04-17
CN1289526C (zh) 2006-12-13
SK500890A3 (en) 2001-04-09
EP0423980B1 (en) 2000-07-12
SK281484B6 (sk) 2001-04-09
CZ286303B6 (cs) 2000-03-15
CN1075078C (zh) 2001-11-21
CZ49097A3 (cs) 2000-01-12
EP0423980A1 (en) 1991-04-24
US6207802B1 (en) 2001-03-27
DE69033584T2 (de) 2001-03-08
DE69034258D1 (de) 2008-09-18
CN1051937A (zh) 1991-06-05
CZ48897A3 (cs) 2000-01-12

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