ATE403713T1 - Stamzellfaktor - Google Patents
StamzellfaktorInfo
- Publication number
- ATE403713T1 ATE403713T1 AT99122861T AT99122861T ATE403713T1 AT E403713 T1 ATE403713 T1 AT E403713T1 AT 99122861 T AT99122861 T AT 99122861T AT 99122861 T AT99122861 T AT 99122861T AT E403713 T1 ATE403713 T1 AT E403713T1
- Authority
- AT
- Austria
- Prior art keywords
- scf
- dna sequence
- stem cell
- cell factor
- biological activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42238389A | 1989-10-16 | 1989-10-16 | |
US53719890A | 1990-06-11 | 1990-06-11 | |
US57361690A | 1990-08-24 | 1990-08-24 | |
PCT/US1990/005548 WO1991005795A1 (en) | 1989-10-16 | 1990-09-28 | Stem cell factor |
US58970190A | 1990-10-01 | 1990-10-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE403713T1 true ATE403713T1 (de) | 2008-08-15 |
Family
ID=27503703
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90310899T ATE194651T1 (de) | 1989-10-16 | 1990-10-04 | Stammzellenfaktor |
AT99122861T ATE403713T1 (de) | 1989-10-16 | 1990-10-04 | Stamzellfaktor |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90310899T ATE194651T1 (de) | 1989-10-16 | 1990-10-04 | Stammzellenfaktor |
Country Status (11)
Country | Link |
---|---|
US (3) | US6218148B1 (de) |
EP (4) | EP1241258A3 (de) |
CN (2) | CN1075078C (de) |
AT (2) | ATE194651T1 (de) |
CZ (3) | CZ286305B6 (de) |
DE (2) | DE69034258D1 (de) |
DK (1) | DK0423980T3 (de) |
GR (1) | GR3034559T3 (de) |
HK (1) | HK1010397A1 (de) |
SG (2) | SG59931A1 (de) |
SK (2) | SK500890A3 (de) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6759215B1 (en) * | 1989-10-16 | 2004-07-06 | Amgen Inc. | Method of preparing human stem cell factor polypeptide |
EP0536317A1 (de) * | 1990-06-25 | 1993-04-14 | Immunex Corporation | Wachstumsfaktor der mastzellen |
US20030125519A1 (en) | 1990-08-27 | 2003-07-03 | Peter Besmer | Ligand for the c-kit receptor and methods of use thereof |
US5767074A (en) * | 1990-08-27 | 1998-06-16 | Sloan-Kettering Institute For Cancer Research | Compositions of soluble C-kit ligand and hematopoietic factors |
US20050276784A1 (en) * | 1990-08-27 | 2005-12-15 | Solan-Kettering Institute For Cancer Research | Ligand for the c-kit receptor and methods of use thereof |
DE4224050A1 (de) * | 1991-07-31 | 1993-02-04 | Hoffmann La Roche | Loesliche kit-liganden |
AU675429B2 (en) * | 1992-04-23 | 1997-02-06 | Sloan-Kettering Institute For Cancer Research | Ligand for the c-kit receptor and methods of use thereof |
US6001803A (en) * | 1992-04-23 | 1999-12-14 | Sloan-Kettering Institute For Cancer Research | Composition of c-kit ligand, GM-CSF, and TNF-α and method of use |
US6288030B1 (en) | 1993-12-22 | 2001-09-11 | Amgen Inc. | Stem cell factor formulations and methods |
US5525708A (en) * | 1994-03-28 | 1996-06-11 | Cytomed, Inc. | Covalent dimer of kit ligand |
ATE299934T1 (de) * | 1994-11-04 | 2005-08-15 | Applied Research Systems | Menschliche scf, eine spleissvariante davon,ihre pharmazeutische verwendung |
US5824789A (en) * | 1995-06-07 | 1998-10-20 | Systemix, Inc. | Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof |
US5731284A (en) * | 1995-09-28 | 1998-03-24 | Amgen Inc. | Method for treating Alzheimer's disease using glial line-derived neurotrophic factor (GDNF) protein product |
US6184200B1 (en) | 1995-09-28 | 2001-02-06 | Amgen Inc. | Truncated glial cell line-derived neurotrophic factor |
EP0871487B1 (de) | 1995-10-04 | 2009-05-27 | Immunex Corporation | Stimulationsfaktor für dendriten |
US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
US5641749A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
US5741778A (en) * | 1996-03-19 | 1998-04-21 | Amgen Inc. | Method for treating Huntington's disease using glial cell line-derived neurotrophic factor (GDNF) protein product |
US5885962A (en) * | 1996-04-05 | 1999-03-23 | Amgen Inc. | Stem cell factor analog compositions and method |
EP0953354A4 (de) * | 1996-08-13 | 2002-10-23 | Fujisawa Pharmaceutical Co | Hämatopoietische stammzellen proliferierende wirkstoffe |
US5969105A (en) * | 1996-10-25 | 1999-10-19 | Feng; Yiqing | Stem cell factor receptor agonists |
US6967092B1 (en) | 1996-10-25 | 2005-11-22 | Mc Kearn John P | Multi-functional chimeric hematopoietic receptor agonists |
JPH10158188A (ja) * | 1996-11-29 | 1998-06-16 | Senju Pharmaceut Co Ltd | 角膜治療用組成物 |
AU2511901A (en) * | 1999-12-23 | 2001-07-09 | Universite De Geneve | Basolateral sorting signal and inhibitors thereof |
AU2001276831A1 (en) | 2000-06-22 | 2002-01-02 | Rxkinetix, Inc. | Delivery vehicle composition and methods for delivering antigens and other drugs |
AU2001273041A1 (en) * | 2000-06-26 | 2002-01-08 | Board Of Regents Of The University Of Nebraska | Methods for use of delivery composition for expanding, activating, committing ormobilizing one or more pluripotent, self-renewing and committed stem cells |
CA2449978A1 (en) * | 2001-06-15 | 2002-12-27 | Johns Hopkins Singapore Pte Ltd | Biofunctional fibers |
WO2003039232A2 (en) * | 2001-10-26 | 2003-05-15 | Large Scale Biology Corporation | Endothelial cell derived hemotopoietic growth factor |
CA2469135A1 (en) * | 2001-11-27 | 2003-06-05 | Nexyte Ab | Production of eukaryotic proteins and nucleic acid molecules in c. elegans |
AU2003208524A1 (en) | 2003-02-14 | 2004-09-06 | Istituto Superiore Di Sanita | Stem cell factor for preventing chemotherapy-induced depletion of blood cells |
CN100345971C (zh) * | 2003-07-14 | 2007-10-31 | 第二军医大学免疫学研究所 | 重组人干细胞因子的原核表达载体、工程菌及制备方法 |
ES2616337T3 (es) | 2003-12-12 | 2017-06-12 | Government Of The United States Of America, As Repr. By The Secr. Of The Dept. Of Health And Human Services And His Successors | Un epítopo de linfocito T citotóxico humano y su epítopo agonista del número no variable de secuencias de repetición en tándem de MUC-1 |
WO2006002344A1 (en) * | 2004-06-23 | 2006-01-05 | Epigenomics Ag | Methods and nucleic acids for the detection of metastasis of colon cell proliferative disorders |
JP2008505650A (ja) * | 2004-07-12 | 2008-02-28 | ソリン・グループ・イタリア・ソシエタ・ア・レスポンサビリタ・リミタータ | ヒト細胞を増殖させるための装置及び方法 |
WO2006055260A2 (en) | 2004-11-05 | 2006-05-26 | Northwestern University | Use of scf and g-csf in the treatment of cerebral ischemia and neurological disorders |
JP2008543839A (ja) | 2005-06-14 | 2008-12-04 | アムジェン インコーポレーテッド | 自己緩衝タンパク質製剤 |
AU2006295340B2 (en) * | 2005-08-05 | 2010-11-11 | Amgen Inc. | Stable aqueous protein or antibody pharmaceutical formulations and their preparation |
US8404653B2 (en) * | 2005-11-14 | 2013-03-26 | Enterprise Partners Venture Capital | Membrane bound stem cell factor therapy for ischemic heart |
WO2007102814A2 (en) * | 2006-03-07 | 2007-09-13 | Regenetech, Inc. | Recombinant mammalian molecules and method for production thereof |
WO2007109583A2 (en) | 2006-03-17 | 2007-09-27 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Compositions and methods for prevention or treatment of neoplastic disease in a mammalian subject |
ZA200808123B (en) * | 2006-03-24 | 2010-03-31 | Childrens Medical Center | Method to modulate hematopoietic stem cell growth |
US20100196336A1 (en) | 2006-05-23 | 2010-08-05 | Dongsu Park | Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods |
EP1872790A1 (de) | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | Neue Zusammensetzung zur Erhöhung der Bioverfügbarkeit von Neurturin |
MX2009004164A (es) * | 2006-10-20 | 2009-10-13 | Childrens Medical Center | Metodo para aumentar la regeneracion de tejido. |
AU2008275229B2 (en) | 2007-07-09 | 2014-11-06 | Genentech, Inc. | Prevention of disulfide bond reduction during recombinant production of polypeptides |
US20110206781A1 (en) * | 2008-05-28 | 2011-08-25 | Zon Leonard I | Method to modulate hematopoietic stem cell growth |
EP2351599A4 (de) | 2008-11-14 | 2013-05-08 | Dnavec Corp | Verfahren zur herstellung dendritischer zellen |
US9051548B2 (en) | 2009-02-03 | 2015-06-09 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
WO2010096264A2 (en) | 2009-02-03 | 2010-08-26 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
US20150018408A1 (en) | 2013-07-10 | 2015-01-15 | The Regents Of The University Of Michigan | Therapeutic antibodies and uses thereof |
CN103547288B (zh) | 2011-01-10 | 2016-03-16 | 密执安大学评议会 | 干细胞因子抑制剂 |
US9452186B2 (en) | 2011-12-02 | 2016-09-27 | Fate Therapeutics, Inc. | Enhanced stem cell composition |
EP3381456A1 (de) | 2011-12-02 | 2018-10-03 | Fate Therapeutics, Inc. | Verbesserte verfahren zur behandlung von ischämie |
US10851412B2 (en) | 2013-03-15 | 2020-12-01 | Fate Therapeutics, Inc. | Cell potency assay for therapeutic potential |
US9889451B2 (en) | 2013-08-16 | 2018-02-13 | ADA-ES, Inc. | Method to reduce mercury, acid gas, and particulate emissions |
LT6161B (lt) | 2013-09-27 | 2015-06-25 | Uab Profarma | Granuliocitų kolonijas stimuliuojančio faktoriaus sulieti baltymai su kitais augimo faktoriais, optimaliai su kamieninių ląstelių faktoriumi, ir jų gavimo būdas |
JP6383216B2 (ja) * | 2014-08-08 | 2018-08-29 | シスメックス株式会社 | 血液分析方法、血液分析装置およびプログラム |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
CN105985424B (zh) * | 2015-01-30 | 2019-08-23 | 苏州方舟生物医药有限公司 | 一种干细胞因子功能性肽段及其应用 |
CN105749252A (zh) * | 2016-04-29 | 2016-07-13 | 南方医科大学 | Il-9作为治疗血小板缺少症的药物的应用 |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
CN108541660A (zh) * | 2018-04-24 | 2018-09-18 | 上海动物园 | 动物饲养方法、动物饲养装置及其发酵床 |
EP3844278A4 (de) * | 2018-08-27 | 2022-05-25 | North Carolina State University | Targeting-kit mit splice-switching-oligonukleotiden zur induktion der apoptose von mastzellen |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4695542A (en) * | 1983-10-04 | 1987-09-22 | Dnax Research Institute Of Molecular And Cellular Biology, Inc. | cDNA clones coding for polypeptides exhibiting multi-lineage cellular growth factor activity |
US4810643A (en) * | 1985-08-23 | 1989-03-07 | Kirin- Amgen Inc. | Production of pluripotent granulocyte colony-stimulating factor |
JPS62223126A (ja) | 1986-03-25 | 1987-10-01 | Sankyo Co Ltd | 血液幹細胞成長因子 |
US4959455A (en) | 1986-07-14 | 1990-09-25 | Genetics Institute, Inc. | Primate hematopoietic growth factors IL-3 and pharmaceutical compositions |
US4847325A (en) | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
-
1990
- 1990-10-04 EP EP02008587A patent/EP1241258A3/de not_active Withdrawn
- 1990-10-04 SG SG1996001817A patent/SG59931A1/en unknown
- 1990-10-04 EP EP90310899A patent/EP0423980B1/de not_active Expired - Lifetime
- 1990-10-04 AT AT90310899T patent/ATE194651T1/de not_active IP Right Cessation
- 1990-10-04 DE DE69034258T patent/DE69034258D1/de not_active Expired - Lifetime
- 1990-10-04 EP EP99122861A patent/EP0992579B1/de not_active Expired - Lifetime
- 1990-10-04 AT AT99122861T patent/ATE403713T1/de not_active IP Right Cessation
- 1990-10-04 SG SG1996002213A patent/SG43009A1/en unknown
- 1990-10-04 DK DK90310899T patent/DK0423980T3/da active
- 1990-10-04 EP EP95105391A patent/EP0676470A1/de not_active Withdrawn
- 1990-10-04 DE DE69033584T patent/DE69033584T2/de not_active Expired - Lifetime
- 1990-10-15 SK SK5008-90A patent/SK500890A3/sk not_active IP Right Cessation
- 1990-10-15 SK SK981-99A patent/SK98199A3/sk not_active IP Right Cessation
- 1990-10-16 CN CN90109647A patent/CN1075078C/zh not_active Expired - Lifetime
- 1990-10-16 CN CNB001309781A patent/CN1289526C/zh not_active Expired - Lifetime
-
1993
- 1993-12-21 US US08/172,329 patent/US6218148B1/en not_active Expired - Lifetime
-
1994
- 1994-11-09 US US08/336,728 patent/US6207802B1/en not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/482,918 patent/US6207417B1/en not_active Expired - Lifetime
-
1997
- 1997-02-18 CZ CZ1997491A patent/CZ286305B6/cs not_active IP Right Cessation
- 1997-02-18 CZ CZ1997488A patent/CZ286303B6/cs not_active IP Right Cessation
- 1997-02-18 CZ CZ1997490A patent/CZ286304B6/cs not_active IP Right Cessation
-
1998
- 1998-10-20 HK HK98111343A patent/HK1010397A1/xx not_active IP Right Cessation
-
2000
- 2000-10-04 GR GR20000402249T patent/GR3034559T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1010397A1 (en) | 1999-06-17 |
CZ286305B6 (cs) | 2000-03-15 |
EP0676470A1 (de) | 1995-10-11 |
DK0423980T3 (da) | 2000-10-09 |
CN1289526C (zh) | 2006-12-13 |
CZ49097A3 (cs) | 2000-01-12 |
CN1051937A (zh) | 1991-06-05 |
DE69034258D1 (de) | 2008-09-18 |
DE69033584D1 (de) | 2000-08-17 |
ATE194651T1 (de) | 2000-07-15 |
EP1241258A2 (de) | 2002-09-18 |
EP0992579B1 (de) | 2008-08-06 |
GR3034559T3 (en) | 2001-01-31 |
EP0423980B1 (de) | 2000-07-12 |
CN1306007A (zh) | 2001-08-01 |
CZ49197A3 (cs) | 2000-01-12 |
CN1075078C (zh) | 2001-11-21 |
SG43009A1 (en) | 1997-10-17 |
SK281487B6 (sk) | 2001-04-09 |
SK98199A3 (en) | 2001-04-09 |
SG59931A1 (en) | 1999-02-22 |
CZ286303B6 (cs) | 2000-03-15 |
US6218148B1 (en) | 2001-04-17 |
DE69033584T2 (de) | 2001-03-08 |
SK281484B6 (sk) | 2001-04-09 |
SK500890A3 (en) | 2001-04-09 |
CZ286304B6 (cs) | 2000-03-15 |
EP0423980A1 (de) | 1991-04-24 |
US6207417B1 (en) | 2001-03-27 |
EP1241258A3 (de) | 2003-12-10 |
CZ48897A3 (cs) | 2000-01-12 |
US6207802B1 (en) | 2001-03-27 |
EP0992579A1 (de) | 2000-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |