SG170779A1 - Antitumoral compounds - Google Patents
Antitumoral compoundsInfo
- Publication number
- SG170779A1 SG170779A1 SG201102164-9A SG2011021649A SG170779A1 SG 170779 A1 SG170779 A1 SG 170779A1 SG 2011021649 A SG2011021649 A SG 2011021649A SG 170779 A1 SG170779 A1 SG 170779A1
- Authority
- SG
- Singapore
- Prior art keywords
- antitumoral compounds
- antitumoral
- compounds
- cancer
- compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000259 anti-tumor effect Effects 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Dermatology (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07123882 | 2007-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG170779A1 true SG170779A1 (en) | 2011-05-30 |
Family
ID=40580474
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG201102163-1A SG170778A1 (en) | 2007-12-20 | 2008-12-19 | Antitumoral compounds |
SG201102164-9A SG170779A1 (en) | 2007-12-20 | 2008-12-19 | Antitumoral compounds |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG201102163-1A SG170778A1 (en) | 2007-12-20 | 2008-12-19 | Antitumoral compounds |
Country Status (27)
Country | Link |
---|---|
US (4) | US9187445B2 (ko) |
EP (3) | EP2231633B1 (ko) |
JP (3) | JP5727228B2 (ko) |
KR (3) | KR101639772B1 (ko) |
CN (4) | CN101903367B (ko) |
AT (1) | ATE549313T1 (ko) |
AU (2) | AU2008341671B2 (ko) |
BR (2) | BRPI0821114B8 (ko) |
CA (2) | CA2710087C (ko) |
CY (1) | CY1117245T1 (ko) |
DK (2) | DK2231633T3 (ko) |
ES (3) | ES2578606T3 (ko) |
HK (3) | HK1147998A1 (ko) |
HR (2) | HRP20120464T1 (ko) |
IL (3) | IL206397A (ko) |
MX (2) | MX2010006796A (ko) |
MY (3) | MY155342A (ko) |
NZ (3) | NZ586012A (ko) |
PL (2) | PL2231590T3 (ko) |
PT (2) | PT2231633E (ko) |
RS (2) | RS52343B (ko) |
RU (3) | RU2493147C2 (ko) |
SG (2) | SG170778A1 (ko) |
SI (2) | SI2231590T1 (ko) |
UA (3) | UA104281C2 (ko) |
WO (2) | WO2009080761A1 (ko) |
ZA (3) | ZA201004018B (ko) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2710087C (en) | 2007-12-20 | 2015-06-02 | Pharma Mar, S.A. | Antitumoral compounds |
JP6180115B2 (ja) | 2012-01-05 | 2017-08-16 | 花王株式会社 | 刺激感緩和剤 |
US9527867B2 (en) | 2013-04-16 | 2016-12-27 | Actelion Pharmaceuticals Ltd. | Antibacterial biaromatic derivatives |
GB201309807D0 (en) * | 2013-05-31 | 2013-07-17 | Pharma Mar Sau | Antibody drug conjugates |
CN108467378A (zh) * | 2017-02-23 | 2018-08-31 | 复旦大学 | 一种二氢吡喃酮类化合物及其制备方法和用途 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
US4855086A (en) * | 1982-10-15 | 1989-08-08 | Burroughs Wellcome Co. | Novel pesticides, preparation and use |
JPS61109717A (ja) * | 1984-11-02 | 1986-05-28 | Teruhiko Beppu | 抗腫瘍剤 |
WO1992012140A1 (en) * | 1990-12-28 | 1992-07-23 | Georgia Tech Research Corporation | Peptides ketoamides, ketoacids, and ketoesters |
JPH0539283A (ja) * | 1991-01-31 | 1993-02-19 | Suntory Ltd | 新規物質S−59917a及びその製造方法 |
ZA938019B (en) | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
US5523456A (en) | 1994-09-29 | 1996-06-04 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5681847A (en) * | 1995-12-05 | 1997-10-28 | Harbor Branch Oceanographic Institution, Inc. | Methods of using discodermolide compounds |
US5834506A (en) | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
US5840974A (en) * | 1996-12-04 | 1998-11-24 | Britisch Biotech Pharmaceuticals, Ltd. | Metalloproteinase inhibitors |
EP1112269A2 (en) | 1998-09-11 | 2001-07-04 | Warner-Lambert Company | Hiv protease inhibitors |
US6380400B1 (en) | 1998-09-11 | 2002-04-30 | Victor Fedij | Methods of making dihydropyrone HIV protease inhibitors |
JP2004505890A (ja) * | 2000-04-04 | 2004-02-26 | ノバルティス アクチエンゲゼルシャフト | 抗新生物剤に耐性の細胞を処置する方法 |
AU2003213684C1 (en) * | 2002-03-04 | 2008-10-23 | Merck Hdac Research, Llc | Methods of inducing terminal differentiation |
CA2533335A1 (en) * | 2003-07-25 | 2005-02-17 | Novartis Ag | Substituted lactams and their use as anti-cancer agents |
US7446196B2 (en) * | 2004-06-03 | 2008-11-04 | Kosan Biosciences, Incorporated | Leptomycin compounds |
RU2006142690A (ru) * | 2004-06-03 | 2008-06-10 | Козан Байосайенсиз Инкорпорейтед (Us) | Соединения лептомицина |
WO2007014423A1 (en) * | 2005-08-02 | 2007-02-08 | Medvet Science Pty, Ltd. | Exercise apparatus |
ATE522514T1 (de) | 2006-06-16 | 2011-09-15 | Pharma Mar Sa | Dihydropyran-2-onverbindungen mit antitumorwirkung |
CA2710087C (en) | 2007-12-20 | 2015-06-02 | Pharma Mar, S.A. | Antitumoral compounds |
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2008
- 2008-12-19 CA CA2710087A patent/CA2710087C/en active Active
- 2008-12-19 ES ES13154647.5T patent/ES2578606T3/es active Active
- 2008-12-19 MY MYPI2010002591A patent/MY155342A/en unknown
- 2008-12-19 KR KR1020157016575A patent/KR101639772B1/ko active IP Right Grant
- 2008-12-19 RU RU2010130180/04A patent/RU2493147C2/ru active
- 2008-12-19 RS RS20120242A patent/RS52343B/en unknown
- 2008-12-19 RS RS20140007A patent/RS53140B/en unknown
- 2008-12-19 EP EP08864895.1A patent/EP2231633B1/en active Active
- 2008-12-19 UA UAA201009035A patent/UA104281C2/ru unknown
- 2008-12-19 RU RU2010130253/04A patent/RU2489429C2/ru active
- 2008-12-19 RU RU2013112003/04A patent/RU2528393C9/ru active
- 2008-12-19 ES ES08864895.1T patent/ES2442140T3/es active Active
- 2008-12-19 NZ NZ586012A patent/NZ586012A/en unknown
- 2008-12-19 PL PL08865009T patent/PL2231590T3/pl unknown
- 2008-12-19 DK DK08864895.1T patent/DK2231633T3/da active
- 2008-12-19 KR KR1020107015968A patent/KR101579553B1/ko active IP Right Grant
- 2008-12-19 EP EP08865009A patent/EP2231590B9/en active Active
- 2008-12-19 CN CN200880121840.6A patent/CN101903367B/zh active Active
- 2008-12-19 AU AU2008341671A patent/AU2008341671B2/en not_active Ceased
- 2008-12-19 JP JP2010538769A patent/JP5727228B2/ja active Active
- 2008-12-19 KR KR1020107015965A patent/KR101541436B1/ko active IP Right Grant
- 2008-12-19 PL PL08864895T patent/PL2231633T3/pl unknown
- 2008-12-19 SG SG201102163-1A patent/SG170778A1/en unknown
- 2008-12-19 US US12/746,974 patent/US9187445B2/en active Active
- 2008-12-19 NZ NZ597526A patent/NZ597526A/en unknown
- 2008-12-19 MY MYPI2014002392A patent/MY164533A/en unknown
- 2008-12-19 PT PT88648951T patent/PT2231633E/pt unknown
- 2008-12-19 JP JP2010538765A patent/JP5529038B2/ja active Active
- 2008-12-19 NZ NZ586013A patent/NZ586013A/en unknown
- 2008-12-19 WO PCT/EP2008/068049 patent/WO2009080761A1/en active Application Filing
- 2008-12-19 ES ES08865009T patent/ES2384420T3/es active Active
- 2008-12-19 MX MX2010006796A patent/MX2010006796A/es active IP Right Grant
- 2008-12-19 CN CN2011100568656A patent/CN102174058A/zh active Pending
- 2008-12-19 US US12/746,966 patent/US8710264B2/en active Active
- 2008-12-19 AT AT08865009T patent/ATE549313T1/de active
- 2008-12-19 CN CN2008801218410A patent/CN101903337B/zh active Active
- 2008-12-19 CA CA2715203A patent/CA2715203C/en active Active
- 2008-12-19 DK DK08865009.8T patent/DK2231590T3/da active
- 2008-12-19 BR BRPI0821114A patent/BRPI0821114B8/pt active IP Right Grant
- 2008-12-19 UA UAA201406894A patent/UA119963C2/uk unknown
- 2008-12-19 SI SI200830644T patent/SI2231590T1/sl unknown
- 2008-12-19 BR BRPI0821116A patent/BRPI0821116B8/pt active IP Right Grant
- 2008-12-19 CN CN201110073931.0A patent/CN102190643B/zh active Active
- 2008-12-19 EP EP13154647.5A patent/EP2597091B1/en active Active
- 2008-12-19 UA UAA201009034A patent/UA106967C2/uk unknown
- 2008-12-19 MX MX2010006795A patent/MX2010006795A/es active IP Right Grant
- 2008-12-19 PT PT08865009T patent/PT2231590E/pt unknown
- 2008-12-19 SG SG201102164-9A patent/SG170779A1/en unknown
- 2008-12-19 AU AU2008341670A patent/AU2008341670B2/en not_active Ceased
- 2008-12-19 WO PCT/EP2008/068065 patent/WO2009080769A1/en active Application Filing
- 2008-12-19 MY MYPI2010002590A patent/MY148651A/en unknown
- 2008-12-19 SI SI200831122T patent/SI2231633T1/sl unknown
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2010
- 2010-06-04 ZA ZA2010/04018A patent/ZA201004018B/en unknown
- 2010-06-04 ZA ZA2010/04017A patent/ZA201004017B/en unknown
- 2010-06-15 IL IL206397A patent/IL206397A/en active IP Right Grant
- 2010-06-15 IL IL206396A patent/IL206396A/en active IP Right Grant
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2011
- 2011-03-01 HK HK11102052.8A patent/HK1147998A1/xx not_active IP Right Cessation
- 2011-03-01 HK HK11102050.0A patent/HK1147990A1/xx not_active IP Right Cessation
- 2011-03-01 HK HK13107821.5A patent/HK1180678A1/zh not_active IP Right Cessation
- 2011-08-31 ZA ZA2011/06371A patent/ZA201106371B/en unknown
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2012
- 2012-06-01 HR HRP20120464AT patent/HRP20120464T1/hr unknown
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2013
- 2013-11-24 IL IL229594A patent/IL229594A/en active IP Right Grant
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2014
- 2014-01-08 HR HRP20140015AT patent/HRP20140015T1/hr unknown
- 2014-01-27 CY CY20141100069T patent/CY1117245T1/el unknown
- 2014-04-10 JP JP2014080887A patent/JP5860088B2/ja active Active
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2015
- 2015-08-12 US US14/824,690 patent/US9750759B2/en active Active
- 2015-08-12 US US14/824,699 patent/US9827257B2/en active Active
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