SG158905A1 - Methods for the production of ansamitocins - Google Patents

Methods for the production of ansamitocins

Info

Publication number
SG158905A1
SG158905A1 SG201000399-4A SG2010003994A SG158905A1 SG 158905 A1 SG158905 A1 SG 158905A1 SG 2010003994 A SG2010003994 A SG 2010003994A SG 158905 A1 SG158905 A1 SG 158905A1
Authority
SG
Singapore
Prior art keywords
ansamitocins
production
methods
ansamitocin
purifying
Prior art date
Application number
SG201000399-4A
Other languages
English (en)
Inventor
Kuo Cynthia
Graham S Byng
Wayne C Widdison
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36692550&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG158905(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of SG158905A1 publication Critical patent/SG158905A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG201000399-4A 2005-01-19 2005-12-12 Methods for the production of ansamitocins SG158905A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/037,104 US7432088B2 (en) 2003-05-08 2005-01-19 Methods for the production of ansamitocins

Publications (1)

Publication Number Publication Date
SG158905A1 true SG158905A1 (en) 2010-02-26

Family

ID=36692550

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201000399-4A SG158905A1 (en) 2005-01-19 2005-12-12 Methods for the production of ansamitocins

Country Status (27)

Country Link
US (1) US7432088B2 (pt)
EP (2) EP2514828B1 (pt)
JP (1) JP5106120B2 (pt)
KR (3) KR101515873B1 (pt)
CN (2) CN104745655A (pt)
AU (1) AU2005325166B2 (pt)
BR (1) BRPI0519624B8 (pt)
CA (2) CA2595024C (pt)
CR (1) CR9228A (pt)
CY (1) CY1121372T1 (pt)
DK (1) DK2514828T3 (pt)
EA (1) EA012524B1 (pt)
ES (1) ES2710875T3 (pt)
HK (1) HK1211985A1 (pt)
HU (1) HUE042312T2 (pt)
IL (2) IL183918A (pt)
LT (1) LT2514828T (pt)
MX (1) MX2007008069A (pt)
NO (1) NO342876B1 (pt)
NZ (2) NZ555437A (pt)
PL (1) PL2514828T3 (pt)
PT (1) PT2514828T (pt)
SG (1) SG158905A1 (pt)
SI (1) SI2514828T1 (pt)
TR (1) TR201901647T4 (pt)
WO (1) WO2006078368A1 (pt)
ZA (1) ZA200704918B (pt)

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CA2659076A1 (en) * 2006-07-10 2008-08-07 Sicor Inc. Apparatus for the separation of a resin from a reaction mixture
CN100420754C (zh) * 2006-10-26 2008-09-24 浙江海正药业股份有限公司 一种制备蒽莎姆菌素的方法
US9090693B2 (en) 2007-01-25 2015-07-28 Dana-Farber Cancer Institute Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
JP5618549B2 (ja) 2007-03-15 2014-11-05 ルードヴィッヒ インスティテュート フォー キャンサーリサーチ リミテッド Ｅｇｆｒ抗体及びｓｒｃ阻害剤を用いる治療方法及び関連製剤
WO2009012256A1 (en) 2007-07-16 2009-01-22 Genentech, Inc. Humanized anti-cd79b antibodies and immunoconjugates and methods of use
DK2474557T3 (da) 2007-07-16 2014-11-10 Genentech Inc Anti-CD79b-antistoffer og immunkonjugater og fremgangsmåder til anvendelse
JP5532486B2 (ja) 2007-08-14 2014-06-25 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ Ｅｇｆ受容体を標的とするモノクローナル抗体１７５ならびにその誘導体および用途
DK2657253T3 (en) 2008-01-31 2017-10-09 Genentech Inc Anti-CD79b antibodies and immune conjugates and methods of use
EP2644204B1 (en) 2008-03-18 2017-04-19 Genentech, Inc. Combinations of an Anti-HER2 antibody-drug conjugate and pertuzumab
CN101319241B (zh) * 2008-07-17 2011-03-30 上海交通大学 安丝菌素的固体发酵方法
US8466260B2 (en) 2009-04-01 2013-06-18 Genentech, Inc. Anti-FcRH5 antibodies and immunoconjugates and methods of use
TW201129380A (en) 2009-12-04 2011-09-01 Genentech Inc Methods of treating metastatic breast cancer with trastuzumab-MCC-DM1
CN101921817A (zh) * 2010-09-07 2010-12-22 上海交通大学 安莎霉素发酵产量提高方法
ES2544608T3 (es) 2010-11-17 2015-09-02 Genentech, Inc. Conjugados de anticuerpo y de alaninil-maitansinol
US8852435B2 (en) * 2011-11-29 2014-10-07 Therapeutics Proteins International, LLC Purification and separation treatment assembly (PASTA) for biological products
CN103255184B (zh) * 2012-02-15 2016-01-27 百奥泰生物科技(广州)有限公司 生产安丝菌素的发酵培养基
CN103805648B (zh) * 2012-11-13 2017-09-15 百奥泰生物科技(广州)有限公司 高产安丝菌素发酵工艺
US10208125B2 (en) 2013-07-15 2019-02-19 University of Pittsburgh—of the Commonwealth System of Higher Education Anti-mucin 1 binding agents and uses thereof
TWI541022B (zh) 2013-12-18 2016-07-11 應克隆公司 針對纖維母細胞生長因子受體－３（ｆｇｆｒ３）之化合物及治療方法
TW201711702A (zh) 2015-06-04 2017-04-01 應克隆公司 使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法
CN113607945A (zh) 2015-07-07 2021-11-05 豪夫迈·罗氏有限公司 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法
CN105907681B (zh) * 2016-05-30 2019-11-19 苏州康聚生物科技有限公司 一种高产安丝菌素p-3的突变株及安丝菌素p-3的制备方法
CN108276427A (zh) * 2018-01-14 2018-07-13 常州大学 一种安丝菌素p-3的提取与分离纯化方法
CN108330113B (zh) * 2018-03-08 2019-05-28 山东省医药生物技术研究中心（山东省病毒研究所） 一株高底物专一性酰基转移酶的珍贵束丝放线菌及其应用
CN113444106A (zh) * 2020-03-25 2021-09-28 重庆乾泰生物医药有限公司 一种高纯度安丝菌素的制备方法
CN112630368A (zh) * 2020-12-18 2021-04-09 卓和药业集团有限公司 安丝菌素含量的高效液相色谱检测分析方法
CN117597450A (zh) * 2021-06-18 2024-02-23 杭州中美华东制药有限公司 安丝菌素p-3的提纯方法
CN115477658A (zh) * 2022-10-12 2022-12-16 道中道（菏泽）制药有限公司 一种有效降低安丝菌素p-3杂质的结晶方法

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US6573074B2 (en) * 2000-04-12 2003-06-03 Smithkline Beecham Plc Methods for ansamitocin production
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US6790954B2 (en) * 2002-01-29 2004-09-14 Immunogen, Inc. Mutant Actinosynnema pretiosum strain with increased maytansinoid production
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Also Published As

Publication number Publication date
CN101103120A (zh) 2008-01-09
ZA200704918B (en) 2008-11-26
DK2514828T3 (en) 2019-03-11
KR101515873B1 (ko) 2015-04-29
EP2514828B1 (en) 2018-11-14
MX2007008069A (es) 2007-08-21
AU2005325166B2 (en) 2012-02-02
CA2595024A1 (en) 2006-07-27
EA200701310A1 (ru) 2008-06-30
CN104745655A (zh) 2015-07-01
US7432088B2 (en) 2008-10-07
PL2514828T3 (pl) 2019-04-30
TR201901647T4 (tr) 2019-02-21
NO20074222L (no) 2007-10-18
NZ583446A (en) 2011-08-26
EP1838863A4 (en) 2011-10-05
JP2008526267A (ja) 2008-07-24
BRPI0519624B8 (pt) 2021-05-25
IL183918A (en) 2013-07-31
BRPI0519624B1 (pt) 2021-01-19
IL215686A0 (en) 2011-11-30
NO342876B1 (no) 2018-08-20
SI2514828T1 (sl) 2019-03-29
HK1211985A1 (en) 2016-06-03
CA2834033A1 (en) 2006-07-27
KR20120099734A (ko) 2012-09-11
AU2005325166A1 (en) 2006-07-27
KR20070099576A (ko) 2007-10-09
PT2514828T (pt) 2019-02-15
CA2834033C (en) 2017-01-24
NZ555437A (en) 2010-04-30
CA2595024C (en) 2014-02-04
IL215686A (en) 2013-07-31
ES2710875T3 (es) 2019-04-29
WO2006078368A1 (en) 2006-07-27
JP5106120B2 (ja) 2012-12-26
CR9228A (es) 2008-03-31
CY1121372T1 (el) 2020-05-29
EP1838863A1 (en) 2007-10-03
BRPI0519624A2 (pt) 2009-02-25
HUE042312T2 (hu) 2019-06-28
LT2514828T (lt) 2019-02-25
KR20130051019A (ko) 2013-05-16
EA012524B1 (ru) 2009-10-30
US20050170475A1 (en) 2005-08-04
EP2514828A3 (en) 2013-07-03
IL183918A0 (en) 2007-10-31
EP2514828A2 (en) 2012-10-24

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