SG138443A1 - Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same - Google Patents

Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same

Info

Publication number
SG138443A1
SG138443A1 SG200305904-5A SG2003059045A SG138443A1 SG 138443 A1 SG138443 A1 SG 138443A1 SG 2003059045 A SG2003059045 A SG 2003059045A SG 138443 A1 SG138443 A1 SG 138443A1
Authority
SG
Singapore
Prior art keywords
preparing
methods
pharmaceutically acceptable
acceptable salts
same
Prior art date
Application number
SG200305904-5A
Other languages
English (en)
Inventor
Fang-Yu Lee
Shan-Chiung Chen
Bin-Ken Chen
Chiung-Ju Tsai
Yen-Ling Yi
Original Assignee
Yung Shin Pharm Ind Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yung Shin Pharm Ind Co Ltd filed Critical Yung Shin Pharm Ind Co Ltd
Publication of SG138443A1 publication Critical patent/SG138443A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SG200305904-5A 2002-10-02 2003-10-02 Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same SG138443A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/262,098 US7166641B2 (en) 2002-10-02 2002-10-02 Pharmaceutically acceptable salts containing local anesthetic and anti-inflammatory activities and methods for preparing the same

Publications (1)

Publication Number Publication Date
SG138443A1 true SG138443A1 (en) 2008-01-28

Family

ID=31993546

Family Applications (2)

Application Number Title Priority Date Filing Date
SG200305904-5A SG138443A1 (en) 2002-10-02 2003-10-02 Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same
SG200606884-5A SG155042A1 (en) 2002-10-02 2003-10-02 Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG200606884-5A SG155042A1 (en) 2002-10-02 2003-10-02 Pharmaceutically acceptable salts containing local anesthetic and anti- inflammatory activities and methods for preparing the same

Country Status (10)

Country Link
US (1) US7166641B2 (zh)
EP (1) EP1405646B1 (zh)
JP (1) JP4819309B2 (zh)
CN (1) CN100574753C (zh)
AT (1) ATE381348T1 (zh)
CA (1) CA2444208C (zh)
DE (1) DE60318159T2 (zh)
HK (1) HK1064937A1 (zh)
SG (2) SG138443A1 (zh)
TW (1) TWI254636B (zh)

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US20070190190A1 (en) * 2006-02-14 2007-08-16 Ramirez Jose E Conditioning compositions and methods of use thereof
US20090053290A1 (en) * 2006-03-08 2009-02-26 Sand Bruce J Transdermal drug delivery compositions and topical compositions for application on the skin
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WO2008093686A1 (ja) 2007-01-29 2008-08-07 Medrx Co., Ltd. 非ステロイド系抗炎症薬と有機アミン化合物との塩とその用途
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WO2010078258A1 (en) * 2008-12-29 2010-07-08 The Board Of Trustees Of The University Of Alabama Compounds comprising two or more biologically functional ions and method of treating parkinson's disease
WO2010087947A2 (en) * 2009-01-30 2010-08-05 Kydes Pharmaceuticals, Llc Transdermal delivery of diclofenac, carbamazepine and benzydamine
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TWI418347B (zh) * 2009-10-21 2013-12-11 Yung Shin Pharm Ind Co Ltd 治療疱疹病毒感染的方法
AU2010331355B2 (en) 2009-12-15 2014-04-24 Teikoku Seiyaku Co., Ltd. Piroxicam-containing endermic preparation
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US9925264B2 (en) 2011-05-10 2018-03-27 Itochu Chemical Frontier Corporation Non-aqueous patch
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US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
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US10813897B2 (en) 2011-12-27 2020-10-27 Cmpd Licensing, Llc Composition and method for compounded therapy
US11213501B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
US11213500B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
US9468599B2 (en) 2011-12-27 2016-10-18 Cmpd Licensing, Llc Composition and method for compounded therapy
US9962391B2 (en) 2011-12-27 2018-05-08 Cmpd Licensing, Llc Composition and method for compounded therapy
US20140161972A1 (en) * 2012-12-09 2014-06-12 National Sun Yat-Sen University Method for forming conductive film at room temperature
ES2697343T3 (es) * 2015-05-28 2019-01-23 Abdi Ibrahim Ilac Sanayi Ve Ticaret A S Formulación de gel que comprende agentes analgésicos y anestésicos
WO2017199181A1 (en) * 2016-05-17 2017-11-23 Alberta Veterinary Laboratories Ltd Topical composition for the control of pain in animals
CN106680391B (zh) * 2016-12-23 2019-11-19 中国农业科学院兰州畜牧与兽药研究所 一种牛奶中双氯芬酸钠残留量的检测方法
WO2018141661A1 (en) 2017-01-31 2018-08-09 Grünenthal GmbH Pharmaceutical patch comprising lidocaine and diclofenac for treating neuropathic pain
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US20200085770A1 (en) * 2017-06-16 2020-03-19 Medrx Co., Ltd. Anti-Inflammatory and Analgesic Drug for External Use
CN113194938A (zh) * 2018-12-19 2021-07-30 美德阿利克斯株式会社 消炎镇痛外用剂
CN111807985A (zh) * 2020-06-17 2020-10-23 西安医学院 一种利多卡因非甾体抗炎药离子液体及其制备方法
RU2749264C1 (ru) * 2020-07-10 2021-06-07 Андрей Александрович Чубаев Фармацевтическая композиция, обладающая противовоспалительным и местноанестезирующим действием
CN112198262B (zh) * 2020-11-04 2022-10-04 宁夏医科大学 水样中非甾体类抗炎药物的检测方法
CN116840378B (zh) * 2023-07-11 2024-03-22 加立(深圳)生物科技有限公司 一种检测罗哌卡因/美洛昔康盐的一水合物含量的方法
CN117420095B (zh) * 2023-12-15 2024-03-01 乐比(广州)健康产业有限公司 一种鼻腔喷雾剂成分检测方法

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Also Published As

Publication number Publication date
US20040068007A1 (en) 2004-04-08
CN100574753C (zh) 2009-12-30
EP1405646A2 (en) 2004-04-07
JP2004285044A (ja) 2004-10-14
TW200410676A (en) 2004-07-01
DE60318159T2 (de) 2008-04-10
US7166641B2 (en) 2007-01-23
TWI254636B (en) 2006-05-11
HK1064937A1 (en) 2005-02-08
CA2444208C (en) 2009-02-24
CA2444208A1 (en) 2004-04-02
DE60318159D1 (de) 2008-01-31
EP1405646A3 (en) 2004-04-21
ATE381348T1 (de) 2008-01-15
SG155042A1 (en) 2009-09-30
JP4819309B2 (ja) 2011-11-24
CN1486690A (zh) 2004-04-07
EP1405646B1 (en) 2007-12-19

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