SG120970A1 - Cyclothiocarbamate derivatives as progesterone receptor modulators - Google Patents

Cyclothiocarbamate derivatives as progesterone receptor modulators

Info

Publication number
SG120970A1
SG120970A1 SG200400081A SG200400081A SG120970A1 SG 120970 A1 SG120970 A1 SG 120970A1 SG 200400081 A SG200400081 A SG 200400081A SG 200400081 A SG200400081 A SG 200400081A SG 120970 A1 SG120970 A1 SG 120970A1
Authority
SG
Singapore
Prior art keywords
alkyl
optionally substituted
aryl
ring
groups
Prior art date
Application number
SG200400081A
Other languages
English (en)
Inventor
Zhang Puwen
Andrew Fensome
Eugene A Terefenko
Zhi Lin
Todd K Jones
Christopher M Tegley
Original Assignee
Ligand Pharm Inc
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/552,354 external-priority patent/US6436929B1/en
Application filed by Ligand Pharm Inc, Wyeth Corp filed Critical Ligand Pharm Inc
Publication of SG120970A1 publication Critical patent/SG120970A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG200400081A 1999-05-04 2000-05-01 Cyclothiocarbamate derivatives as progesterone receptor modulators SG120970A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18301399P 1999-05-04 1999-05-04
US09/552,354 US6436929B1 (en) 1999-05-04 2000-04-19 Cyclothiocarbamate derivatives as progesterone receptor modulators

Publications (1)

Publication Number Publication Date
SG120970A1 true SG120970A1 (en) 2006-04-26

Family

ID=26878649

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200400081A SG120970A1 (en) 1999-05-04 2000-05-01 Cyclothiocarbamate derivatives as progesterone receptor modulators

Country Status (24)

Country Link
EP (1) EP1175411B1 (cs)
JP (2) JP4958338B2 (cs)
KR (1) KR100732692B1 (cs)
CN (1) CN1131856C (cs)
AT (1) ATE386729T1 (cs)
AU (1) AU766801B2 (cs)
BG (1) BG65277B1 (cs)
BR (1) BR0010214A (cs)
CA (1) CA2371712C (cs)
CZ (1) CZ20013952A3 (cs)
DE (1) DE60038108T2 (cs)
DK (1) DK1175411T3 (cs)
EA (1) EA004511B1 (cs)
ES (1) ES2301482T3 (cs)
GE (1) GEP20043181B (cs)
HU (1) HUP0203332A3 (cs)
IL (1) IL146298A0 (cs)
MX (1) MXPA01011287A (cs)
NO (1) NO321370B1 (cs)
NZ (1) NZ515353A (cs)
PL (1) PL351083A1 (cs)
SG (1) SG120970A1 (cs)
SK (1) SK15922001A3 (cs)
TR (1) TR200103285T2 (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203332A3 (en) * 1999-05-04 2004-12-28 Wyeth Corp Cyclothiocarbamate derivatives, their use as progesterone receptor modulators and pharmaceutical compositions containing them
US6407101B1 (en) * 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
ATE409699T1 (de) * 2004-04-08 2008-10-15 Wyeth Corp Verfahren zur minimierung von thioamidverunreinigungen
WO2005100346A1 (en) * 2004-04-08 2005-10-27 Wyeth Thioamide derivatives as progesterone receptor modulators
MXPA06012402A (es) * 2004-04-27 2007-01-17 Wyeth Corp Carbamato y tiocarbamato biarilos ciclicos que contienen cianopirrol y metodos para preparar los mismos.
AU2005237520B2 (en) 2004-04-27 2012-01-19 Wyeth Purification of progesterone receptor modulators
US20060009428A1 (en) * 2004-07-07 2006-01-12 Wyeth Cyclic progestin regimens and kits
PT1778710E (pt) * 2004-08-13 2012-04-12 Wyeth Llc Derivados de tanaproget, metabolitos e suas utilizações
DE602006012972D1 (de) 2005-04-28 2010-04-29 Wyeth Corp Mikronisierte tanaproget zusammensetzungen und verfahren zu ihrer herstellung
WO2006116498A2 (en) * 2005-04-28 2006-11-02 Wyeth Purified form of tanaproget
EP1874278B1 (en) * 2005-04-28 2009-06-24 Wyeth Compositions containing micronized tanaproget
BRPI0610431A2 (pt) 2005-04-28 2012-10-23 Wyeth Corp composição farmacêutica, processo para preparar uma composição, cápsula, e, kit farmacêutico
MX2007013469A (es) * 2005-04-28 2008-01-22 Wyeth Corp Forma ii polimorfa de tanaproget.
JP5339903B2 (ja) * 2005-06-09 2013-11-13 ワイス・エルエルシー エチニルエストラジオールを含むタナプロゲット組成物

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
WO1996019458A2 (en) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
WO1998014436A1 (en) * 1996-10-02 1998-04-09 Dupont Pharmaceuticals Company 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0510235A (ja) * 1991-07-05 1993-01-19 Nippondenso Co Ltd 内燃機関の点火時期制御装置
US5688810A (en) * 1994-12-22 1997-11-18 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
HUP0203332A3 (en) * 1999-05-04 2004-12-28 Wyeth Corp Cyclothiocarbamate derivatives, their use as progesterone receptor modulators and pharmaceutical compositions containing them
BRPI0610431A2 (pt) * 2005-04-28 2012-10-23 Wyeth Corp composição farmacêutica, processo para preparar uma composição, cápsula, e, kit farmacêutico
JP5339903B2 (ja) * 2005-06-09 2013-11-13 ワイス・エルエルシー エチニルエストラジオールを含むタナプロゲット組成物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0510235A1 (en) * 1991-04-26 1992-10-28 Dong-A Pharm. Co., Ltd. Novel benzoxazine or benzothiazine derivatives and process for the preparation of the same
WO1995020389A1 (en) * 1994-01-28 1995-08-03 Merck & Co., Inc. Benzoxazinones as inhibitors of hiv reverse transcriptase
WO1996019458A2 (en) * 1994-12-22 1996-06-27 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
WO1998014436A1 (en) * 1996-10-02 1998-04-09 Dupont Pharmaceuticals Company 4,4-disubstituted-1,4-dihydro-2h-3,1-benzoxazin-2-ones useful as hiv reverse transcriptase inhibitors and intermediates and processes for making the same

Also Published As

Publication number Publication date
JP5523430B2 (ja) 2014-06-18
NZ515353A (en) 2004-03-26
CZ20013952A3 (cs) 2002-05-15
AU4811900A (en) 2000-11-17
TR200103285T2 (tr) 2002-02-21
GEP20043181B (en) 2004-02-25
PL351083A1 (en) 2003-03-10
CA2371712C (en) 2009-12-22
DE60038108T2 (de) 2009-02-12
DK1175411T3 (da) 2008-06-09
KR20020000170A (ko) 2002-01-04
CN1349516A (zh) 2002-05-15
BR0010214A (pt) 2002-02-13
NO321370B1 (no) 2006-05-02
IL146298A0 (en) 2002-07-25
JP2002543192A (ja) 2002-12-17
JP4958338B2 (ja) 2012-06-20
ES2301482T3 (es) 2008-07-01
EA004511B1 (ru) 2004-04-29
CN1131856C (zh) 2003-12-24
MXPA01011287A (es) 2003-07-14
CA2371712A1 (en) 2000-11-09
HUP0203332A2 (hu) 2003-01-28
EP1175411B1 (en) 2008-02-20
NO20015381D0 (no) 2001-11-02
AU766801B2 (en) 2003-10-23
HUP0203332A3 (en) 2004-12-28
JP2012087129A (ja) 2012-05-10
KR100732692B1 (ko) 2007-06-27
ATE386729T1 (de) 2008-03-15
EA200101181A1 (ru) 2002-04-25
BG65277B1 (bg) 2007-11-30
SK15922001A3 (sk) 2002-09-10
NO20015381L (no) 2002-01-03
DE60038108D1 (de) 2008-04-03
BG106080A (en) 2002-05-31
EP1175411A1 (en) 2002-01-30

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