US2776926A
(en)
|
1955-08-04 |
1957-01-08 |
Eugene S Sharpe |
Preparation of alpha-ketoglutaric acid by serratia marcescens
|
US2917528A
(en)
|
1956-08-24 |
1959-12-15 |
Victor Chemical Works |
Alkanolaminealkanephosphonic acids and salts thereof
|
US2841616A
(en)
*
|
1956-10-30 |
1958-07-01 |
Campbell Soup Co |
Process for the recovery of alpha-ketoglutaric acid
|
US3875304A
(en)
|
1970-04-24 |
1975-04-01 |
Schlitz Brewing Co J |
Livestock feed composition and method of preparing the same
|
US4045585A
(en)
|
1976-05-19 |
1977-08-30 |
Decel Corporation |
Flavored animal food compositions
|
DE3151196A1
(de)
*
|
1981-12-23 |
1983-06-30 |
Kurt Heinz Prof. Dr. 7800 Freiburg Bauer |
Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen
|
US6451341B1
(en)
|
1990-02-05 |
2002-09-17 |
Thomas J. Slaga |
Time release formulation of vitamins, minerals and other beneficial supplements
|
US5646187A
(en)
|
1992-05-20 |
1997-07-08 |
Ab Erik Vinnars |
Use of alpha-ketoglutarate
|
US6306430B1
(en)
|
1998-04-16 |
2001-10-23 |
The Iams Company |
Process for decreasing adiposity using vitamin a as a dietary supplement
|
US6905707B2
(en)
|
1998-05-28 |
2005-06-14 |
Medical Research Institute |
Controlled release arginine alpha ketoglutarate
|
CO5140079A1
(es)
|
1998-10-14 |
2002-03-22 |
Novartis Ag |
Composicion farmaceutica de liberacion sostenida y metodo para liberar un agente farmaceuticamente activo de liberacion sostenida y metodo para liberar un agente far- maceuticamente activo
|
US6649654B1
(en)
|
1999-11-23 |
2003-11-18 |
The Regents Of The University Of California |
Methods for identifying and using IKK inhibitors
|
AU2895502A
(en)
|
2000-12-20 |
2002-07-01 |
Alcon Universal Ltd |
Solution for removing cataracts via liquefracture
|
AU2004237437B2
(en)
*
|
2003-05-07 |
2011-01-20 |
Osteologix A/S |
Controlled release composition containing a strontium salt
|
KR20110124317A
(ko)
*
|
2004-05-06 |
2011-11-16 |
오스테올로지스 에이에스 |
금속 유기 염의 제조를 위한 고 수율 및 고속 합성 방법
|
PL368572A1
(en)
|
2004-06-17 |
2005-12-27 |
Sgp & Sons Ab |
Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections
|
CA2574597A1
(en)
|
2004-08-09 |
2006-02-16 |
Cancer Research Technology Limited |
Alpha-ketoglutarates and their use as therapeutic agents
|
ES2510690T3
(es)
|
2004-12-17 |
2014-10-21 |
Alan B. Cash |
Método para extender la esperanza de vida y retrasar la aparición de enfermedad relacionada con la edad
|
US20060234250A1
(en)
|
2005-04-15 |
2006-10-19 |
Powers Ralph W Iii |
Methods of screening and compositions for life span modulators
|
US20070135376A1
(en)
|
2005-06-20 |
2007-06-14 |
Accera, Inc. |
Method to reduce oxidative damage and improve mitochondrial efficiency
|
WO2007053943A1
(en)
|
2005-11-08 |
2007-05-18 |
Multi Formulations Ltd. |
The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance
|
US8367121B2
(en)
|
2005-11-23 |
2013-02-05 |
Florida A & M University |
Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease
|
PL379512A1
(pl)
|
2006-04-21 |
2007-10-29 |
Sgp & Sons Ab |
Nowe metody i ich zastosowanie
|
PL226695B1
(pl)
|
2006-07-03 |
2017-08-31 |
Danuta Kruszewska |
Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori
|
WO2008115783A1
(en)
|
2007-03-19 |
2008-09-25 |
Metaproteomics, Llc |
Methods and compositions for promoting bone and joint health
|
EP2173336B1
(en)
|
2007-07-02 |
2016-03-30 |
Protista Biotechnology AB |
Alpha-ketoglutaric acid for use in the treatment of hypertension or pulmonary hypertension
|
EP2033623A1
(en)
|
2007-09-07 |
2009-03-11 |
Cutech S.R.L. |
Compositions comprising ornithine ketoglutarate (OKG)
|
JP5406643B2
(ja)
|
2008-09-22 |
2014-02-05 |
日本合成化学工業株式会社 |
α−オキソカルボン酸の金属塩の製造方法
|
CN101759553A
(zh)
|
2008-11-21 |
2010-06-30 |
扬子江药业集团北京海燕药业有限公司 |
α-酮酸钙的制备方法
|
DE102009016119A1
(de)
|
2009-04-03 |
2010-10-14 |
Evonik Degussa Gmbh |
Nahrungsergänzungsmittel enthaltend alpha-Ketosäuren zur Unterstützung der Diabetestherapie
|
ES2685947T3
(es)
|
2009-04-10 |
2018-10-15 |
Haiyan Qi |
Agentes antienvejecimiento
|
MX2011011947A
(es)
|
2009-05-11 |
2012-01-30 |
Berg Biosystems Llc |
Metodos para el diagnostico de trastornos metabolicos usando intercambiadores epimetabolicos, moleculas intracelulares multidimensionales, o influyentes ambientales.
|
EP2434908A2
(en)
|
2009-05-28 |
2012-04-04 |
The IAMS Company |
Pet food in the form of a coated kibble
|
US9050277B2
(en)
|
2009-06-12 |
2015-06-09 |
Generex Pharmaceuticals, Inc. |
Combined Geum japonicum and Centella asiatica extracts for the therapeutic treatment of heart failure
|
ES2600909T3
(es)
|
2009-06-30 |
2017-02-13 |
Derman Biomedicine Co. Ltd. |
Composiciones que contienen berberina o análogos de la misma para tratar rosácea o trastornos de la piel relacionados con enrojecimiento de la cara
|
WO2011060305A1
(en)
|
2009-11-12 |
2011-05-19 |
Nox Technologies, Inc. |
Potato skin compositions that lower cytosolic nadh level to mimic calorie restriction
|
WO2012114204A2
(en)
|
2011-02-15 |
2012-08-30 |
Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto |
Methods of treating mitochondrial dysfunction
|
AU2012244750A1
(en)
|
2011-04-18 |
2013-10-17 |
Nestec S.A. |
Nutritional compositions having alpha-HICA and eicosapentaenoic acid
|
WO2012174537A2
(en)
|
2011-06-16 |
2012-12-20 |
President And Fellows Of Harvard College |
Small molecule screening for mouse satellite cell proliferation
|
CN102586347B
(zh)
*
|
2012-03-06 |
2014-04-09 |
江南大学 |
一种两阶段pH控制高产a-酮戊二酸的方法
|
US9532997B2
(en)
|
2012-04-03 |
2017-01-03 |
Whitehead Institute For Biomedical Research |
Compositions and methods for promoting intestinal stem cell function
|
ITBO20120226A1
(it)
|
2012-04-24 |
2013-10-25 |
Alfa Wassermann Spa |
Composizioni comprendenti ornitina alfa-chetoglutarato, processi per il loro ottenimento e il loro uso.
|
JP6029058B2
(ja)
|
2012-09-14 |
2016-11-24 |
国立研究開発法人農業・食品産業技術総合研究機構 |
シュウ酸カルシウムを含む氷核活性剤
|
KR102198633B1
(ko)
|
2012-09-19 |
2021-01-05 |
그레스포 에이비 |
뇌기능 향상용 조성물
|
CN102976927A
(zh)
*
|
2012-12-26 |
2013-03-20 |
天津天成制药有限公司 |
α-酮戊二酸钙的制备方法
|
WO2014103475A1
(ja)
|
2012-12-27 |
2014-07-03 |
株式会社林原 |
アンチエイジング用皮膚外用組成物及びその製造方法
|
US20150328176A1
(en)
|
2013-01-25 |
2015-11-19 |
Winning The Fight Inc. |
Composition for treatment of neurodegenerative disease
|
US9511057B2
(en)
|
2013-03-15 |
2016-12-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for treating denervation-induced muscle atrophy
|
NZ711433A
(en)
|
2013-03-19 |
2017-03-31 |
Univ South Florida |
Compositions and methods for producing elevated and sustained ketosis
|
US20160263092A1
(en)
|
2013-12-19 |
2016-09-15 |
Twi Biotechnology, Inc. |
Therapeutic uses of berberine formulations
|
WO2015123229A1
(en)
|
2014-02-12 |
2015-08-20 |
The Regents Of The University Of California |
Compositions and methods for treating aging and age-related diseases and symptoms
|
US10258639B2
(en)
|
2014-05-06 |
2019-04-16 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy
|
CA2953387C
(en)
|
2014-06-30 |
2023-11-28 |
The Regents Of The University Of California |
Ketobutyrate compounds and compositions for treating age-related symptoms and diseases
|
BR112017001623B1
(pt)
|
2014-07-29 |
2022-11-29 |
Shenzhen Hightide Biopharmaceutical, Ltd |
Sal de adição ácido-base em uma forma substancialmente pura, composição farmacêutica compreendendo uma quantidade do referido sal e seus usos
|
WO2016019224A1
(en)
|
2014-07-31 |
2016-02-04 |
Indiana University Research And Technology Corporation |
Antithetical regulation of endothelial ace and ace2 by brg1-foxm1 complex underlies pathological cardiac hypertrophy
|
CN104529755B
(zh)
*
|
2014-12-29 |
2016-01-06 |
精晶药业股份有限公司 |
一种从转化液中分离α-酮戊二酸的方法
|
JP2018517666A
(ja)
|
2015-04-06 |
2018-07-05 |
シンセン ハイタイド バイオファーマシューティカル リミテッド |
ウルソデオキシコール酸、ベルベリンまたはl−カルニチンのコンジュゲート化合物、ならびにその組成物および方法
|
ES2932801T3
(es)
|
2015-06-10 |
2023-01-26 |
Elysium Health Inc |
Composiciones de ribósido de nicotinamida y pterostilbeno y métodos para el tratamiento de trastornos de la piel
|
US20180193458A1
(en)
|
2015-07-08 |
2018-07-12 |
Unity Biotechnology, Inc. |
Compositions and methods for treating senescence-associated diseases and disorders
|
WO2018064468A1
(en)
|
2016-09-30 |
2018-04-05 |
The Regents Of The University Of California |
Alpha-ketobutyrate, alpha-ketoglutarate, and 2-hydroxybutyrate for stimulating hair growth
|
PL231635B1
(pl)
*
|
2017-01-03 |
2019-03-29 |
Politechnika Poznanska |
Sposób produkcji kwasu alfa-ketoglutarowego (AKG) z jednoskładnikowych roztworów wodnych
|
MX2017004010A
(es)
|
2017-03-27 |
2018-02-09 |
Antonio Hernandez Miramontes Jorge |
Mezcla de oxalacetato, alfacetoglutarato, ácido tartánico y sales de lactato de calcio y sodio, para tratar pacientes con insuficiencia renal crónica.
|
BR112019022455A2
(pt)
|
2017-04-25 |
2020-05-12 |
Buck Institute For Research On Aging |
Formulações para prolongar o tempo de vida e de saúde
|
WO2019038655A1
(en)
|
2017-08-21 |
2019-02-28 |
The Regents Of The University Of California |
COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASES
|
JP7499259B2
(ja)
|
2018-09-25 |
2024-06-13 |
ポンス デ レオン ヘルス デジグネイテッド アクティビティ カンパニー |
αケトグルタル酸カルシウムを製造するためのプロセス
|
WO2020086733A1
(en)
|
2018-10-24 |
2020-04-30 |
Ponce De Leon Health Designated Activity Company |
Nicotinamide riboside compositions for healthspan extension
|
CN114126599A
(zh)
|
2019-06-10 |
2022-03-01 |
巴克老龄化研究所 |
改变衰老相关分泌表型的方法和组合物
|
JP2022537685A
(ja)
*
|
2019-06-10 |
2022-08-29 |
ポンス デ レオン ヘルス デジクネイテッド アクティビティ カンパニー |
アルファ-ケトグルタル酸塩の持続放出組成物
|
WO2022006500A1
(en)
|
2020-07-02 |
2022-01-06 |
Ponce De Leon Health Designated Activity Company |
Compositions and methods for treating crp-mediated diseases
|
CN115974679A
(zh)
*
|
2022-12-20 |
2023-04-18 |
绍兴市精益生物化工有限公司 |
α-酮戊二酸钙盐制备方法
|