SG11202004740RA - Anti-alpha synuclein antibodies - Google Patents
Anti-alpha synuclein antibodiesInfo
- Publication number
- SG11202004740RA SG11202004740RA SG11202004740RA SG11202004740RA SG11202004740RA SG 11202004740R A SG11202004740R A SG 11202004740RA SG 11202004740R A SG11202004740R A SG 11202004740RA SG 11202004740R A SG11202004740R A SG 11202004740RA SG 11202004740R A SG11202004740R A SG 11202004740RA
- Authority
- SG
- Singapore
- Prior art keywords
- alpha synuclein
- synuclein antibodies
- antibodies
- alpha
- synuclein
- Prior art date
Links
- 102000019355 Synuclein Human genes 0.000 title 1
- 108050006783 Synuclein Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Psychology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Microbiology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1720970.1A GB201720970D0 (en) | 2017-12-15 | 2017-12-15 | Antibodies |
PCT/EP2018/084689 WO2019115671A1 (en) | 2017-12-15 | 2018-12-13 | Anti-alpha synuclein antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202004740RA true SG11202004740RA (en) | 2020-06-29 |
Family
ID=61008785
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202004740RA SG11202004740RA (en) | 2017-12-15 | 2018-12-13 | Anti-alpha synuclein antibodies |
Country Status (23)
Country | Link |
---|---|
US (2) | US11292831B2 (ja) |
EP (1) | EP3724228A1 (ja) |
JP (1) | JP7326281B2 (ja) |
KR (1) | KR20200099168A (ja) |
CN (1) | CN111655727A (ja) |
AU (1) | AU2018382527A1 (ja) |
BR (1) | BR112020010508A2 (ja) |
CA (1) | CA3084106A1 (ja) |
CL (1) | CL2020001607A1 (ja) |
EA (1) | EA202091482A1 (ja) |
EC (1) | ECSP20039610A (ja) |
GB (1) | GB201720970D0 (ja) |
IL (2) | IL275223B2 (ja) |
MA (1) | MA51134A (ja) |
MX (1) | MX2020005810A (ja) |
PE (1) | PE20201062A1 (ja) |
PH (1) | PH12020551006A1 (ja) |
SG (1) | SG11202004740RA (ja) |
TN (1) | TN2020000077A1 (ja) |
TW (2) | TW202346343A (ja) |
UY (1) | UY38012A (ja) |
WO (1) | WO2019115671A1 (ja) |
ZA (2) | ZA202003414B (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG11201906947SA (en) | 2017-02-17 | 2019-08-27 | Bristol Myers Squibb Co | Antibodies to alpha-synuclein and uses thereof |
AU2020350769A1 (en) * | 2019-09-20 | 2022-03-31 | Denali Therapeutics Inc. | Anti-alpha-synuclein antibodies and methods of use thereof |
KR20220110539A (ko) * | 2019-12-04 | 2022-08-08 | 에이씨 이뮨 에스에이 | 치료 및 진단용 신규 분자 |
CN116209719A (zh) | 2020-08-07 | 2023-06-02 | 株式会社Lg化学 | 热塑性树脂组合物 |
CN113912715B (zh) * | 2021-12-15 | 2022-03-01 | 北京凯祥弘康生物科技有限公司 | 一种抗α-突触核蛋白抗体及其相关产品和应用 |
WO2023221892A1 (zh) * | 2022-05-20 | 2023-11-23 | 长春金赛药业有限责任公司 | 抗α-Synuclein抗体及其用途 |
CN115043927B (zh) * | 2022-06-17 | 2024-03-19 | 武汉大学 | 针对抗α-突触核蛋白K80Hcy抗体的抗原肽及其应用 |
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WO2002050121A1 (fr) | 2000-12-13 | 2002-06-27 | Taisho Pharmaceutical Co.,Ltd. | Nouvel anticorps |
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US7674599B2 (en) | 2003-11-08 | 2010-03-09 | Elan Pharmaceuticals, Inc. | Methods of using antibodies to detect alpha-synuclein in fluid samples |
EA013752B1 (ru) | 2004-08-09 | 2010-06-30 | Элан Фармасьютикалз, Инк. | Предупреждение и лечение синуклеинопатических и амилоидогенных заболеваний |
WO2007021255A1 (en) * | 2005-08-09 | 2007-02-22 | Elan Pharmaceuticals, Inc. | Antibodies to alpha-synuclein |
JP5558834B2 (ja) | 2007-02-23 | 2014-07-23 | ヤンセン アルツハイマー イミュノセラピー | シヌクレイノパチーおよびアミロイド形成疾患(amyloidogenicdisease)の予防および処置 |
US8147833B2 (en) | 2007-02-23 | 2012-04-03 | Neotope Biosciences Limited | Prevention and treatment of synucleinopathic and amyloidogenic disease |
LT3067066T (lt) * | 2007-02-23 | 2019-06-25 | Prothena Biosciences Limited | Sinukleopatinių ir amiloidogeninių ligų prevencija ir gydymas |
CN101289665A (zh) * | 2007-04-18 | 2008-10-22 | 复旦大学 | 一种建立抗帕金森病动物模型的方法 |
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EP2366714A1 (en) | 2010-03-03 | 2011-09-21 | Dr. Rentschler Holding GmbH & Co. KG | Naturally occuring autoantibodies against alpha-synuclein that inhibit the aggregation and cytotoxicity of alpha-synuclein |
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BR112018016717A2 (pt) | 2016-12-16 | 2018-12-26 | H Lundbeck As | agentes, usos e métodos |
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SG11201906947SA (en) | 2017-02-17 | 2019-08-27 | Bristol Myers Squibb Co | Antibodies to alpha-synuclein and uses thereof |
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EP3635393A4 (en) | 2017-05-16 | 2021-03-10 | Claudio Soto-Jara | DETECTION OF MISFOLDED TAU PROTEIN |
WO2018237338A1 (en) | 2017-06-23 | 2018-12-27 | Denali Therapeutics Inc. | ANTI-ALPHA-SYNCUCIN ANTIBODIES AND METHODS OF USE |
-
2017
- 2017-12-15 GB GBGB1720970.1A patent/GB201720970D0/en not_active Ceased
-
2018
- 2018-12-13 CA CA3084106A patent/CA3084106A1/en active Pending
- 2018-12-13 SG SG11202004740RA patent/SG11202004740RA/en unknown
- 2018-12-13 EA EA202091482A patent/EA202091482A1/ru unknown
- 2018-12-13 WO PCT/EP2018/084689 patent/WO2019115671A1/en active Application Filing
- 2018-12-13 IL IL275223A patent/IL275223B2/en unknown
- 2018-12-13 PE PE2020000717A patent/PE20201062A1/es unknown
- 2018-12-13 MX MX2020005810A patent/MX2020005810A/es unknown
- 2018-12-13 MA MA051134A patent/MA51134A/fr unknown
- 2018-12-13 BR BR112020010508-2A patent/BR112020010508A2/pt unknown
- 2018-12-13 IL IL303672A patent/IL303672B1/en unknown
- 2018-12-13 CN CN201880080860.7A patent/CN111655727A/zh active Pending
- 2018-12-13 EP EP18829766.7A patent/EP3724228A1/en active Pending
- 2018-12-13 TN TNP/2020/000077A patent/TN2020000077A1/en unknown
- 2018-12-13 JP JP2020532563A patent/JP7326281B2/ja active Active
- 2018-12-13 AU AU2018382527A patent/AU2018382527A1/en active Pending
- 2018-12-13 KR KR1020207020006A patent/KR20200099168A/ko unknown
- 2018-12-13 US US16/772,043 patent/US11292831B2/en active Active
- 2018-12-14 TW TW112129007A patent/TW202346343A/zh unknown
- 2018-12-14 TW TW107145231A patent/TWI806940B/zh active
- 2018-12-14 UY UY0001038012A patent/UY38012A/es not_active Application Discontinuation
-
2020
- 2020-06-08 ZA ZA2020/03414A patent/ZA202003414B/en unknown
- 2020-06-14 PH PH12020551006A patent/PH12020551006A1/en unknown
- 2020-06-15 CL CL2020001607A patent/CL2020001607A1/es unknown
- 2020-07-14 EC ECSENADI202039610A patent/ECSP20039610A/es unknown
-
2021
- 2021-09-01 ZA ZA2021/06370A patent/ZA202106370B/en unknown
-
2022
- 2022-02-28 US US17/682,082 patent/US20220340648A1/en active Pending
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