SG11201804885TA - Monomaleimide-functionalized platinum compounds for cancer therapy - Google Patents

Monomaleimide-functionalized platinum compounds for cancer therapy

Info

Publication number
SG11201804885TA
SG11201804885TA SG11201804885TA SG11201804885TA SG11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA SG 11201804885T A SG11201804885T A SG 11201804885TA
Authority
SG
Singapore
Prior art keywords
wien
international
monomaleimide
pct
platinum compounds
Prior art date
Application number
SG11201804885TA
Other languages
English (en)
Inventor
Christian Kowol
Petra Heffeter
Walter Berger
Bernhard K Keppler
Josef Mayr
Verena Pichler
Original Assignee
Univ Wien Med
Univ Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wien Med, Univ Wien filed Critical Univ Wien Med
Publication of SG11201804885TA publication Critical patent/SG11201804885TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201804885TA 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy SG11201804885TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15198739 2015-12-09
PCT/EP2016/080453 WO2017097986A1 (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Publications (1)

Publication Number Publication Date
SG11201804885TA true SG11201804885TA (en) 2018-07-30

Family

ID=54849106

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201804885TA SG11201804885TA (en) 2015-12-09 2016-12-09 Monomaleimide-functionalized platinum compounds for cancer therapy

Country Status (21)

Country Link
US (2) US10723748B2 (enExample)
EP (1) EP3386997B1 (enExample)
JP (1) JP6867652B2 (enExample)
CN (1) CN108368143B (enExample)
AU (1) AU2016367306B2 (enExample)
CA (1) CA3004630A1 (enExample)
CY (1) CY1124529T1 (enExample)
DK (1) DK3386997T3 (enExample)
ES (1) ES2898704T3 (enExample)
HR (1) HRP20211466T1 (enExample)
HU (1) HUE056897T2 (enExample)
IL (1) IL259864B (enExample)
LT (1) LT3386997T (enExample)
MX (1) MX377528B (enExample)
PL (1) PL3386997T3 (enExample)
PT (1) PT3386997T (enExample)
RS (1) RS62412B1 (enExample)
SG (1) SG11201804885TA (enExample)
SI (1) SI3386997T1 (enExample)
SM (1) SMT202100709T1 (enExample)
WO (1) WO2017097986A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101915452B1 (ko) * 2014-06-23 2018-11-06 플라콘 테라퓨틱스 인코포레이티드 백금 화합물, 조성물 및 이의 용도
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Hdac抑制劑與pd-l1抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
CN109171001A (zh) * 2018-09-14 2019-01-11 上海烟草集团有限责任公司 草酸钠在降低卷烟烟气中TSNAs释放量中的应用
JP2023508996A (ja) * 2019-12-31 2023-03-06 キネート バイオファーマ インク. Cdk12/13阻害剤を用いる癌の処置
CN114163479B (zh) * 2020-09-11 2025-05-16 上海海聚生物科技有限公司 一类治疗癌症用的铂类化合物及其制备方法
US20230339997A1 (en) * 2020-09-11 2023-10-26 Shanghai Haiju Biological Technology Co., Ltd. Class of platinum compounds for treating cancer, and method for preparation thereof
CN114539320A (zh) * 2020-11-25 2022-05-27 北京大学 辐射激活的四价铂配合物及其用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
CH605550A5 (enExample) 1972-06-08 1978-09-29 Research Corp
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
DE3218121A1 (de) 1982-05-14 1983-11-17 Leskovar, Peter, Dr.-Ing., 8000 München Arzneimittel zur tumorbehandlung
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
JPS607934A (ja) 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造方法
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
ATE59966T1 (de) 1983-09-26 1991-02-15 Ehrenfeld Udo Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
DE3474511D1 (en) 1983-11-01 1988-11-17 Terumo Corp Pharmaceutical composition containing urokinase
CS269719B1 (en) 1986-12-29 1990-05-14 Kiss Frantisek Platinum cytostatic
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
DE19636889A1 (de) 1996-09-11 1998-03-12 Felix Dr Kratz Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel
WO1999016421A1 (en) 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
JP4169478B2 (ja) 1998-04-21 2008-10-22 マイクロメット アーゲー Cd19×cd3特異的ポリペプチドおよびその使用
DE19926154A1 (de) 1999-06-09 2000-12-14 Ktb Tumorforschungs Gmbh Verfahren zur Herstellung einer injizierbaren Arzneimittelzubereitung
AUPQ641100A0 (en) 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
DK1280520T4 (en) 2000-05-10 2018-06-25 Novartis Ag Phospholipid based powders for drug delivery
ES2364636T3 (es) 2001-12-19 2011-09-08 Novartis Ag Administración pulmonar de aminoglucósidos.
DE10314780A1 (de) 2003-03-19 2004-09-30 Ktb Tumorforschungsgesellschaft Mbh Proteinbindende Derivate von Platinkomplexen mit Cyclobutan-1,1-dicarboxylatliganden
HRP20050902A2 (en) 2003-03-31 2005-12-31 Pliva-Lachema A.S. Pharmaceutical composition containing platinum complex as active substance and method of manufacturing thereof
CZ2004945A3 (cs) 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ296459B6 (cs) 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
US20060205810A1 (en) 2004-11-24 2006-09-14 Schering Corporation Platinum therapeutic combinations
CZ300120B6 (cs) 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
CZ300590B6 (cs) 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CA2857398A1 (en) 2011-12-05 2013-06-13 Igenica Biotherapeutics, Inc. Antibody-drug conjugates and related compounds, compositions, and methods
KR102057356B1 (ko) * 2012-02-27 2019-12-18 아뮤닉스 파마슈티컬스, 인크. Xten 콘주게이트 조성물 및 그의 제조 방법
CN105722847A (zh) * 2013-10-08 2016-06-29 阿特莱斯遗传学有限公司 标记化合物和它们在测定中的用途
EP3089745A4 (en) 2013-12-31 2017-05-17 Placon Therapeutics, Inc. Compounds, compositions, and methods for the treatment of cancers
KR101915452B1 (ko) * 2014-06-23 2018-11-06 플라콘 테라퓨틱스 인코포레이티드 백금 화합물, 조성물 및 이의 용도
JP6876631B2 (ja) 2015-06-23 2021-05-26 プラコン セラピューティクス インコーポレイテッドPlacon Therapeutics,Inc. 白金化合物、組成物及びその使用
US20180186823A1 (en) 2015-06-23 2018-07-05 Placon Therapeutics, Inc. Platinum compounds, compositions, and uses thereof
WO2017004123A1 (en) 2015-06-29 2017-01-05 Case Western Reserve University Anticancer drug-containing plant virus particles
AU2015242213A1 (en) 2015-07-12 2018-03-08 Hangzhou Dac Biotech Co., Ltd Bridge linkers for conjugation of cell-binding molecules
US10639378B2 (en) 2016-06-06 2020-05-05 Genentech, Inc. Silvestrol antibody-drug conjugates and methods of use
TW202434291A (zh) 2016-07-08 2024-09-01 美商建南德克公司 人類副睪蛋白4 (he4)用於評定癌症治療反應性之用途
WO2018026742A1 (en) 2016-08-01 2018-02-08 Askgene Pharma Inc. Novel antibody-albumin-drug conjugates (aadc) and methods for using them
CN108164512B (zh) 2017-12-27 2021-05-25 沈阳药科大学 一类具有生物粘附作用的马来酰亚胺型前药及其在口服药物传递中的应用
CN108187063B (zh) 2018-01-09 2020-09-08 沈阳药科大学 白蛋白结合型抗肿瘤药-马来酰亚胺分子前药

Also Published As

Publication number Publication date
PL3386997T3 (pl) 2021-12-13
RS62412B1 (sr) 2021-10-29
CN108368143B (zh) 2022-02-01
HRP20211466T1 (hr) 2021-12-24
US10723748B2 (en) 2020-07-28
JP6867652B2 (ja) 2021-05-12
US11572379B2 (en) 2023-02-07
AU2016367306B2 (en) 2021-04-22
SMT202100709T1 (it) 2022-01-10
CA3004630A1 (en) 2017-06-15
IL259864B (en) 2022-07-01
DK3386997T3 (da) 2021-09-20
HUE056897T2 (hu) 2022-03-28
CN108368143A (zh) 2018-08-03
SI3386997T1 (sl) 2021-11-30
IL259864A (en) 2018-07-31
LT3386997T (lt) 2021-12-10
CY1124529T1 (el) 2022-07-22
US20210002313A1 (en) 2021-01-07
ES2898704T3 (es) 2022-03-08
PT3386997T (pt) 2021-11-04
EP3386997A1 (en) 2018-10-17
MX2018006953A (es) 2019-05-16
JP2018538292A (ja) 2018-12-27
AU2016367306A1 (en) 2018-06-14
WO2017097986A1 (en) 2017-06-15
MX377528B (es) 2025-03-10
US20180354979A1 (en) 2018-12-13
EP3386997B1 (en) 2021-06-30

Similar Documents

Publication Publication Date Title
SG11201804885TA (en) Monomaleimide-functionalized platinum compounds for cancer therapy
SG11201808990QA (en) Compositions for topical application of compounds
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201407537YA (en) Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
SG11201500005SA (en) Pyrimidine pyrazolyl derivatives
SG11201808222RA (en) Methods of treatment of cholestatic diseases
SG11201900163PA (en) Macrocycle kinase inhibitors
SG11201804814YA (en) Materials and methods for delivering nucleic acids to cochlear and vestibular cells
SG11201805888SA (en) Cyclic dinucleotides for treating conditions associated with sting activity such as cancer
SG11201811564QA (en) Methods of treating ovarian cancer
SG11201407859YA (en) Methods of treating cancer using pd-l1 axis binding antagonists and vegf antagonists
SG11201811230RA (en) Compositions and methods for reducing ocular neovascularization
SG11201810485SA (en) Substituted carbonucleoside derivatives useful as anticancer agents
SG11201804704PA (en) Compositions and methods for decreasing tau expression
SG11201408318RA (en) Compositions and methods for transmucosal absorption
SG11201808106YA (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
SG11201804890TA (en) Bipyrazolyl derivatives useful for the treatment of autoimmune diseases
SG11201808237UA (en) Substituted indole compound derivatives as dengue viral replication inhibitors
SG11201906436VA (en) Novel heterocyclic compound, its preparation method, and pharmaceutical composition comprising the same
SG11201902531QA (en) Liquid pharmaceutical composition
SG11202000333UA (en) Bicyclic ketone compounds and methods of use thereof
SG11201805149XA (en) Compositions comprising 15-hepe and methods of using the same
SG11201809537VA (en) Urea motif containing compounds and derivatives thereof as antibacterial drugs
SG11201809875VA (en) Compositions and methods for treating spinal muscular atrophy
SG11201810940XA (en) Methods of treating pancreatic cancer