SG11201802957PA - Platform for the induction & maintenance of ground state pluripotency - Google Patents

Platform for the induction & maintenance of ground state pluripotency

Info

Publication number
SG11201802957PA
SG11201802957PA SG11201802957PA SG11201802957PA SG11201802957PA SG 11201802957P A SG11201802957P A SG 11201802957PA SG 11201802957P A SG11201802957P A SG 11201802957PA SG 11201802957P A SG11201802957P A SG 11201802957PA SG 11201802957P A SG11201802957P A SG 11201802957PA
Authority
SG
Singapore
Prior art keywords
induction
platform
maintenance
ground state
state pluripotency
Prior art date
Application number
SG11201802957PA
Other languages
English (en)
Inventor
Bahram Valamehr
Megan Robinson
Ramzey Abujarour
Original Assignee
Fate Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fate Therapeutics Inc filed Critical Fate Therapeutics Inc
Publication of SG11201802957PA publication Critical patent/SG11201802957PA/en

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C12N2015/8518—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic expressing industrially exogenous proteins, e.g. for pharmaceutical use, human insulin, blood factors, immunoglobulins, pseudoparticles
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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    • C12N2740/00—Reverse transcribing RNA viruses
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    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18611—Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18641—Use of virus, viral particle or viral elements as a vector
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    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18811—Sendai virus
    • C12N2760/18841—Use of virus, viral particle or viral elements as a vector
    • C12N2760/18843—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/108—Plasmid DNA episomal vectors
    • C—CHEMISTRY; METALLURGY
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/002—Vectors comprising a special translation-regulating system controllable or inducible
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    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/007—Vectors comprising a special translation-regulating system cell or tissue specific
SG11201802957PA 2015-10-16 2016-10-14 Platform for the induction & maintenance of ground state pluripotency SG11201802957PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562242842P 2015-10-16 2015-10-16
PCT/US2016/057136 WO2017066634A1 (en) 2015-10-16 2016-10-14 Platform for the induction & maintenance of ground state pluripotency

Publications (1)

Publication Number Publication Date
SG11201802957PA true SG11201802957PA (en) 2018-05-30

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SG11201802957PA SG11201802957PA (en) 2015-10-16 2016-10-14 Platform for the induction & maintenance of ground state pluripotency
SG10202111851YA SG10202111851YA (en) 2015-10-16 2016-10-14 Platform for the Induction & Maintenance of Ground State Pluripotency

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG10202111851YA SG10202111851YA (en) 2015-10-16 2016-10-14 Platform for the Induction & Maintenance of Ground State Pluripotency

Country Status (9)

Country Link
US (2) US11441126B2 (zh)
EP (1) EP3362570A4 (zh)
JP (3) JP7263005B2 (zh)
KR (1) KR20180055918A (zh)
CN (2) CN108291237B (zh)
AU (2) AU2016338680B2 (zh)
CA (1) CA3001917A1 (zh)
SG (2) SG11201802957PA (zh)
WO (1) WO2017066634A1 (zh)

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KR20140063501A (ko) 2010-12-22 2014-05-27 페이트 세러퓨틱스, 인코포레이티드 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼
EP3604499A1 (en) 2014-03-04 2020-02-05 Fate Therapeutics, Inc. Improved reprogramming methods and cell culture platforms
WO2019165320A1 (en) * 2018-02-22 2019-08-29 Celularity, Inc. Post partum tissue-derived induced pluripotent stem cells and uses thereof

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