SG11201606176YA - Heterocyclic compound - Google Patents

Heterocyclic compound

Info

Publication number
SG11201606176YA
SG11201606176YA SG11201606176YA SG11201606176YA SG11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA SG 11201606176Y A SG11201606176Y A SG 11201606176YA
Authority
SG
Singapore
Prior art keywords
heterocyclic compound
heterocyclic
compound
Prior art date
Application number
SG11201606176YA
Other languages
English (en)
Inventor
Zenichi Ikeda
Minoru Sasaki
Keiko Kakegawa
Fumiaki Kikuchi
Yoichi Nishikawa
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of SG11201606176YA publication Critical patent/SG11201606176YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541Non-condensed thiazines containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201606176YA 2014-02-13 2015-02-12 Heterocyclic compound SG11201606176YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014025944 2014-02-13
PCT/JP2015/000640 WO2015122188A1 (fr) 2014-02-13 2015-02-12 Composé hétérocyclique

Publications (1)

Publication Number Publication Date
SG11201606176YA true SG11201606176YA (en) 2016-08-30

Family

ID=52589730

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201606176YA SG11201606176YA (en) 2014-02-13 2015-02-12 Heterocyclic compound

Country Status (22)

Country Link
US (2) US9428470B2 (fr)
EP (1) EP3105228B1 (fr)
JP (1) JP6458054B2 (fr)
KR (1) KR20160113299A (fr)
CN (1) CN106170487A (fr)
AR (1) AR099399A1 (fr)
AU (1) AU2015216439A1 (fr)
BR (1) BR112016018548A2 (fr)
CA (1) CA2939675A1 (fr)
CL (1) CL2016002023A1 (fr)
CR (1) CR20160368A (fr)
EA (1) EA201691624A1 (fr)
EC (1) ECSP16067163A (fr)
IL (1) IL247018A0 (fr)
MA (1) MA39247B1 (fr)
MX (1) MX2016010561A (fr)
PE (1) PE20161396A1 (fr)
PH (1) PH12016501614A1 (fr)
SG (1) SG11201606176YA (fr)
TW (1) TW201609677A (fr)
UY (1) UY35995A (fr)
WO (1) WO2015122188A1 (fr)

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CN105051008B (zh) 2013-03-13 2018-05-29 武田药品工业株式会社 胍基苯甲酸酯化合物
RU2728790C2 (ru) 2014-02-10 2020-07-31 Фред Хатчинсон Кансэр Рисёч Сентер Лечение сердечного приступа и ишемического повреждения соединениями галогена
US9346776B2 (en) 2014-02-13 2016-05-24 Takeda Pharmaceutical Company Limited Fused heterocyclic compound
BR112016018555B1 (pt) 2014-02-13 2024-01-23 Incyte Holdings Corporation Ciclopropilaminas como inibidores de lsd1, seu uso, composição farmacêutica que os compreende e método de inibição de lsd1
SG11201606689VA (en) 2014-02-13 2016-09-29 Incyte Corp Cyclopropylamines as lsd1 inhibitors
US9428470B2 (en) * 2014-02-13 2016-08-30 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2015123437A1 (fr) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines en tant qu'inhibiteurs de lsd1
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
US9695167B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
WO2016007731A1 (fr) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyridines et imidazopyrazines à utiliser en tant qu'inhibiteurs de lsd1
JP2018080109A (ja) * 2015-03-16 2018-05-24 武田薬品工業株式会社 治療剤
WO2016158788A1 (fr) * 2015-03-27 2016-10-06 武田薬品工業株式会社 Composé hétérocyclique fusionné
US9944647B2 (en) 2015-04-03 2018-04-17 Incyte Corporation Heterocyclic compounds as LSD1 inhibitors
US10329255B2 (en) 2015-08-12 2019-06-25 Incyte Corporation Salts of an LSD1 inhibitor
BR112020008676A2 (pt) 2017-11-02 2020-10-27 Ube Industries, Ltd. composto, e, composição farmacêutica.
EP3778577B1 (fr) 2018-05-09 2023-08-30 Lg Chem, Ltd. Nouveau composé présentant une activité inhibitrice de l'entéropeptidase
AR116019A1 (es) * 2018-08-27 2021-03-25 Scohia Pharma Inc Derivados de guanidinobenzoilo como inhibidores de enteropeptidasa
WO2020047198A1 (fr) 2018-08-31 2020-03-05 Incyte Corporation Sels d'un inhibiteur de lsd1 et leurs procédés de préparation
WO2021013742A1 (fr) 2019-07-19 2021-01-28 Janssen Pharmaceutica Nv Dérivés de [1,2,4]triazolo[1,5-a]pyridinyle 5,8-disubstitués et d'imidazo[1,2-a]pyridine 5,8-disubstitués utiles en tant qu'inhibiteurs de l'entéropeptidase
JP7327788B2 (ja) * 2019-08-06 2023-08-16 学校法人福岡大学 糖化産物生成抑制剤及び医薬組成物
CA3160144A1 (fr) * 2019-11-04 2021-07-08 Faraday Pharmaceuticals, Inc. Utilisation de composes d'iodure pour le traitement et la prevention d'une cardiotoxicite et d'une cachexie associees a une chimiotherapie
WO2021166899A1 (fr) * 2020-02-17 2021-08-26 宇部興産株式会社 Médicament contenant un inhibiteur de protéase gastrique destiné à être utilisé en association avec un mimétique d'incrétine
CN111803652B (zh) * 2020-08-04 2021-09-14 南通康是美生物科技有限公司 治疗痤疮的化合物在制备治疗痤疮的药物组合物或化妆品组合物中的用途

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Also Published As

Publication number Publication date
MA39247A1 (fr) 2017-11-30
CA2939675A1 (fr) 2015-08-20
PH12016501614A1 (en) 2017-02-06
ECSP16067163A (es) 2017-10-31
EP3105228A1 (fr) 2016-12-21
AU2015216439A1 (en) 2016-08-11
UY35995A (es) 2015-08-31
CL2016002023A1 (es) 2017-03-24
IL247018A0 (en) 2016-09-29
US20160347724A1 (en) 2016-12-01
PE20161396A1 (es) 2017-01-10
BR112016018548A2 (pt) 2019-01-15
KR20160113299A (ko) 2016-09-28
CN106170487A (zh) 2016-11-30
TW201609677A (zh) 2016-03-16
US10023544B2 (en) 2018-07-17
EP3105228B1 (fr) 2018-09-26
MX2016010561A (es) 2016-11-16
MA39247B1 (fr) 2018-04-30
US9428470B2 (en) 2016-08-30
US20150225354A1 (en) 2015-08-13
CR20160368A (es) 2016-12-01
JP2017505823A (ja) 2017-02-23
EA201691624A1 (ru) 2017-05-31
AR099399A1 (es) 2016-07-20
JP6458054B2 (ja) 2019-01-23
WO2015122188A1 (fr) 2015-08-20

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