SG11201501684UA - Use of markers in the identification of cardiotoxic agents - Google Patents
Use of markers in the identification of cardiotoxic agentsInfo
- Publication number
- SG11201501684UA SG11201501684UA SG11201501684UA SG11201501684UA SG11201501684UA SG 11201501684U A SG11201501684U A SG 11201501684UA SG 11201501684U A SG11201501684U A SG 11201501684UA SG 11201501684U A SG11201501684U A SG 11201501684UA SG 11201501684U A SG11201501684U A SG 11201501684UA
- Authority
- SG
- Singapore
- Prior art keywords
- markers
- identification
- cardiotoxic agents
- cardiotoxic
- agents
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261700327P | 2012-09-12 | 2012-09-12 | |
| US201261706611P | 2012-09-27 | 2012-09-27 | |
| US201261727104P | 2012-11-15 | 2012-11-15 | |
| US201261727115P | 2012-11-16 | 2012-11-16 | |
| US201261732105P | 2012-11-30 | 2012-11-30 | |
| PCT/US2013/059559 WO2014043421A1 (en) | 2012-09-12 | 2013-09-12 | Use of markers in the identification of cardiotoxic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201501684UA true SG11201501684UA (en) | 2015-04-29 |
Family
ID=50278696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201501684UA SG11201501684UA (en) | 2012-09-12 | 2013-09-12 | Use of markers in the identification of cardiotoxic agents |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10352947B2 (ko) |
| EP (1) | EP2895861A4 (ko) |
| JP (1) | JP6371287B2 (ko) |
| KR (1) | KR20150043566A (ko) |
| CN (2) | CN107255721A (ko) |
| AU (1) | AU2013315371A1 (ko) |
| CA (1) | CA2884637A1 (ko) |
| HK (1) | HK1212767A1 (ko) |
| IL (1) | IL237557A0 (ko) |
| NZ (1) | NZ706155A (ko) |
| SG (1) | SG11201501684UA (ko) |
| WO (1) | WO2014043421A1 (ko) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112014028801A2 (pt) | 2012-05-22 | 2017-07-25 | Berg Llc | ensaios com base em célula interrogatória para identificar marcadores de toxicidade induzida por fármaco |
| WO2014166303A2 (en) * | 2013-04-12 | 2014-10-16 | The Chinese University Of Hong Kong | Use of multiomic signature to predict diabetes |
| US9589043B2 (en) | 2013-08-01 | 2017-03-07 | Actiance, Inc. | Unified context-aware content archive system |
| KR101660328B1 (ko) * | 2014-01-14 | 2016-09-27 | 한국과학기술연구원 | 심혈관 질환 진단용 바이오 마커 |
| US9550981B2 (en) | 2014-01-22 | 2017-01-24 | University Of Washington | Modified tafazzin proteins and methods of making and using the same |
| EP3413052B1 (en) * | 2014-03-26 | 2022-12-28 | Roche Diagnostics GmbH | Igfbp7 for diagnosing diastolic dysfunction |
| US10086040B2 (en) | 2014-12-12 | 2018-10-02 | University Of Washington | Methods for treating and preventing cardiomyopathy with a fusion protein of tafazzin and a cellular permeability peptide |
| US11143659B2 (en) | 2015-01-27 | 2021-10-12 | Arterez, Inc. | Biomarkers of vascular disease |
| WO2017028308A1 (en) * | 2015-08-20 | 2017-02-23 | Bgi Shenzhen | Biomarkers for coronary heart disease |
| CN107543929A (zh) * | 2016-06-23 | 2018-01-05 | 中国医学科学院肿瘤医院 | 基于蛋白标志物hsp90ab1诊断肺癌患者的试剂盒 |
| US10880254B2 (en) | 2016-10-31 | 2020-12-29 | Actiance, Inc. | Techniques for supervising communications from multiple communication modalities |
| CA3057613A1 (en) * | 2017-03-15 | 2018-09-20 | Juneau Biosciences, L.L.C. | Methods of using genetic markers associated with endometriosis |
| JP7032723B2 (ja) * | 2017-07-21 | 2022-03-09 | 公立大学法人福島県立医科大学 | 薬剤の心毒性評価方法及びそのための試薬又はキット |
| CN107944226B (zh) * | 2017-12-19 | 2020-03-27 | 清华大学 | 基于信息论基因转录本组装与量化方法及系统 |
| CN109908368A (zh) * | 2019-01-31 | 2019-06-21 | 中国人民解放军军事科学院军事医学研究院 | 一种senp1基因和/或senp1蛋白在制备治疗心血管疾病药物中的应用 |
| JP2022523564A (ja) | 2019-03-04 | 2022-04-25 | アイオーカレンツ， インコーポレイテッド | 機械学習を使用するデータ圧縮および通信 |
| CN110093412A (zh) * | 2019-03-29 | 2019-08-06 | 南方医科大学南方医院 | 用于诊断动脉粥样硬化的分子标志物ugp2及应用 |
| CN110201152B (zh) * | 2019-06-05 | 2021-08-27 | 重庆大学 | 一种G3bp2多肽疫苗及应用 |
| CN115038717A (zh) * | 2019-11-12 | 2022-09-09 | 慕尼黑工业大学 | 人IL-27α-亚基的同质突变蛋白 |
| CN110850086B (zh) * | 2019-11-18 | 2023-05-02 | 西安交通大学 | 一种肝移植术后缺血性胆道病变血清诊断标志物acly的应用 |
| EP4065986A4 (en) * | 2019-11-26 | 2023-11-15 | Ohio State Innovation Foundation | METHODS AND COMPOSITIONS FOR DETECTING AND MANAGING CARDIOVASCULAR DISEASES |
| CN111710425A (zh) * | 2020-06-19 | 2020-09-25 | 复旦大学附属中山医院 | 一种免疫检查点抑制剂心脏毒性评估方法，系统及装置 |
| KR20220082558A (ko) * | 2020-12-10 | 2022-06-17 | 재단법인 의약바이오컨버젼스연구단 | 면역 증진 활성이 있는 신규 crs 단편 펩타이드 및 이의 용도 |
| CN112608923B (zh) * | 2021-01-17 | 2023-05-12 | 上海捷瑞生物工程有限公司 | 一种抑制ddx17相关rna表达产物的核苷酸及其应用 |
| CN115112776B (zh) * | 2021-03-18 | 2023-07-04 | 中国科学院大连化学物理研究所 | 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒 |
| CN113621698A (zh) * | 2021-08-08 | 2021-11-09 | 华中科技大学同济医学院附属协和医院 | Flnc基因突变体及其应用 |
| CN115011681B (zh) * | 2021-12-31 | 2023-04-18 | 河南省人民医院 | 肥厚型心肌病相关的标志分子及其在诊断肥厚型心肌病中的应用 |
| CN114705859B (zh) * | 2022-04-26 | 2023-02-24 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | 一种用于肝癌骨转移诊断、治疗和预后的生物标志物及其应用 |
| WO2023239197A1 (ko) * | 2022-06-09 | 2023-12-14 | 주식회사 자이메디 | 면역 증진 활성이 있는 신규 crs 단편 펩타이드 및 이의 용도 |
| CN117393154B (zh) * | 2023-12-12 | 2024-03-01 | 中国中医科学院医学实验中心 | 基于血清全通路氧化脂质组学筛选心力衰竭生物标志物的方法及应用 |
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| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| US6951924B2 (en) | 1997-03-14 | 2005-10-04 | Human Genome Sciences, Inc. | Antibodies against secreted protein HTEBYII |
| CA2432978C (en) | 2000-12-22 | 2012-08-28 | Medlyte, Inc. | Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor |
| US7447594B2 (en) | 2001-07-10 | 2008-11-04 | Ocimum Biosolutions, Inc. | Molecular cardiotoxicology modeling |
| US20040014040A1 (en) | 2001-07-10 | 2004-01-22 | Donna Mendrick | Cardiotoxin molecular toxicology modeling |
| US20070054269A1 (en) | 2001-07-10 | 2007-03-08 | Mendrick Donna L | Molecular cardiotoxicology modeling |
| CN1612936A (zh) * | 2001-11-09 | 2005-05-04 | 苏尔斯精细医药公司 | 利用基因表达分布图识别、监控和治疗疾病以及鉴定生物学状态 |
| ES2222775B1 (es) * | 2002-01-31 | 2006-12-16 | Laboratorios Indas, S.A. | Procedimiento para la deteccion de una predisposicion a una enfermedad cardiovascular. |
| AU2002304965A1 (en) | 2002-05-24 | 2003-12-12 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US20040137544A1 (en) * | 2002-10-31 | 2004-07-15 | Roberto Latini | PTX3 as an early prognostic indicator of cardiovascular and cerebrovascular pathologies |
| US8263325B2 (en) | 2002-11-15 | 2012-09-11 | Ottawa Heart Institute Research Corporation | Predicting, detecting and monitoring treatment of cardiomyopathies and myocarditis |
| GB0229747D0 (en) * | 2002-12-20 | 2003-01-29 | Axis Shield Asa | Assay |
| US20090169585A1 (en) | 2003-10-23 | 2009-07-02 | Resveratrol Partners, Llc | Resveratrol-Containing Compositions And Their Use In Modulating Gene Product Concentration Or Activity |
| WO2005053728A2 (de) | 2003-12-01 | 2005-06-16 | Xantos Biomedicine Ag | Mit adipositas assoziierte proteine und deren verwendung in therapie und diagnostik |
| EP2306192B1 (en) | 2003-12-05 | 2015-10-14 | The Cleveland Clinic Foundation | Risk Markers For Cardiovascular Disease |
| JP4667372B2 (ja) * | 2004-02-25 | 2011-04-13 | 株式会社ペルセウスプロテオミクス | 血管障害の程度の判定方法 |
| US9002652B1 (en) | 2005-01-27 | 2015-04-07 | Institute For Systems Biology | Methods for identifying and using organ-specific proteins in blood |
| US7883858B2 (en) | 2005-01-27 | 2011-02-08 | Institute For Systems Biology | Methods for identifying and monitoring drug side effects |
| EP2311985A1 (en) * | 2005-07-27 | 2011-04-20 | Oncotherapy Science, Inc. | Sirna for treating esophageal cancer |
| US20090202995A1 (en) | 2005-08-26 | 2009-08-13 | Mendrick Donna L | Molecular cardiotoxicology modeling |
| EP1996718B1 (en) | 2006-03-06 | 2011-11-30 | Ceetox Inc. | Toxicity screening methods |
| RU2473555C2 (ru) * | 2006-12-19 | 2013-01-27 | ДжинГоу, Инк. | Новые способы функционального анализа большого количества экспериментальных данных и групп генов, идентифицированных из указанных данных |
| AU2008300897B2 (en) | 2007-07-18 | 2014-12-04 | Cellartis Ab | Cardiomyocyte-like cell clusters derived from hBS cells |
| EP2019318A1 (en) | 2007-07-27 | 2009-01-28 | Erasmus University Medical Center Rotterdam | Protein markers for cardiovascular events |
| JP2010540444A (ja) * | 2007-09-20 | 2010-12-24 | レスベラトロル パートナーズ， エルエルシー | 遺伝子産物の濃縮または活性を調節するためのレスベラトロールを含む組成物 |
| WO2009075566A1 (en) * | 2007-12-12 | 2009-06-18 | Erasmus University Medical Center Rotterdam | Biomarkers for cardiovascular disease |
| AU2009294362A1 (en) | 2008-09-18 | 2010-03-25 | Universitetet I Oslo | Use of CTGF as a cardioprotectant |
| JP5678045B2 (ja) | 2009-06-08 | 2015-02-25 | シンギュレックス・インコーポレイテッド | 高感度バイオマーカーパネル |
| CN102884435A (zh) * | 2009-11-27 | 2013-01-16 | 贝克Idi心脏和糖尿病研究院控股有限公司 | 用于稳定和不稳定心脏病的脂质生物标记物 |
| US20120058088A1 (en) | 2010-06-28 | 2012-03-08 | Resveratrol Partners, Llc | Resveratrol-Containing Compositions And Methods Of Use |
| WO2012024296A1 (en) | 2010-08-20 | 2012-02-23 | University Of Miami | Arterial repair with cultured bone marrow cells and whole bone marrow |
| JP5930266B2 (ja) | 2010-08-26 | 2016-06-08 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 遺伝子絞り込み装置、遺伝子絞り込み方法、及びコンピュータプログラム |
| CN102520192B (zh) * | 2011-12-29 | 2014-08-13 | 深圳康美生物科技股份有限公司 | 一种定量检测肌钙蛋白i/肌酸激酶同工酶/肌红蛋白的荧光免疫层析试剂盒 |
| BR112014028801A2 (pt) | 2012-05-22 | 2017-07-25 | Berg Llc | ensaios com base em célula interrogatória para identificar marcadores de toxicidade induzida por fármaco |
-
2013
- 2013-09-12 KR KR20157009405A patent/KR20150043566A/ko not_active Application Discontinuation
- 2013-09-12 CN CN201710443381.4A patent/CN107255721A/zh active Pending
- 2013-09-12 CN CN201380058864.2A patent/CN104781670B/zh not_active Expired - Fee Related
- 2013-09-12 JP JP2015531344A patent/JP6371287B2/ja not_active Expired - Fee Related
- 2013-09-12 WO PCT/US2013/059559 patent/WO2014043421A1/en active Application Filing
- 2013-09-12 EP EP13836849.3A patent/EP2895861A4/en not_active Withdrawn
- 2013-09-12 NZ NZ706155A patent/NZ706155A/en unknown
- 2013-09-12 US US14/025,803 patent/US10352947B2/en active Active
- 2013-09-12 CA CA2884637A patent/CA2884637A1/en not_active Abandoned
- 2013-09-12 AU AU2013315371A patent/AU2013315371A1/en not_active Abandoned
- 2013-09-12 SG SG11201501684UA patent/SG11201501684UA/en unknown
-
2015
- 2015-03-04 IL IL237557A patent/IL237557A0/en unknown
-
2016
- 2016-01-19 HK HK16100530.9A patent/HK1212767A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2884637A1 (en) | 2014-03-20 |
| JP6371287B2 (ja) | 2018-08-08 |
| CN104781670A (zh) | 2015-07-15 |
| CN107255721A (zh) | 2017-10-17 |
| JP2015529335A (ja) | 2015-10-05 |
| HK1212767A1 (zh) | 2016-06-17 |
| EP2895861A1 (en) | 2015-07-22 |
| AU2013315371A1 (en) | 2015-04-09 |
| EP2895861A4 (en) | 2016-06-22 |
| US20140100128A1 (en) | 2014-04-10 |
| KR20150043566A (ko) | 2015-04-22 |
| NZ706155A (en) | 2018-09-28 |
| IL237557A0 (en) | 2015-04-30 |
| CN104781670B (zh) | 2017-07-07 |
| US10352947B2 (en) | 2019-07-16 |
| WO2014043421A1 (en) | 2014-03-20 |
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