SG11201408489PA - Target detection and signal amplification - Google Patents
Target detection and signal amplificationInfo
- Publication number
- SG11201408489PA SG11201408489PA SG11201408489PA SG11201408489PA SG11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA SG 11201408489P A SG11201408489P A SG 11201408489PA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- nsw
- methods
- detection
- sydney
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6823—Release of bound markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/9005—Enzymes with nucleic acid structure; e.g. ribozymes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2012902551A AU2012902551A0 (en) | 2012-06-18 | Target detection and signal amplification | |
| AU2012903462A AU2012903462A0 (en) | 2012-08-10 | Target detection and signal amplification | |
| AU2013202354A AU2013202354A1 (en) | 2012-06-18 | 2013-04-03 | Target detection and signal amplification |
| PCT/AU2013/000651 WO2013188912A1 (en) | 2012-06-18 | 2013-06-18 | Target detection and signal amplification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201408489PA true SG11201408489PA (en) | 2015-01-29 |
Family
ID=49767935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201408489PA SG11201408489PA (en) | 2012-06-18 | 2013-06-18 | Target detection and signal amplification |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9725757B2 (https=) |
| EP (1) | EP2861770B1 (https=) |
| JP (1) | JP6336443B2 (https=) |
| CN (1) | CN104540965B (https=) |
| AU (2) | AU2013202354A1 (https=) |
| CA (1) | CA2876919C (https=) |
| IL (1) | IL236363A0 (https=) |
| IN (1) | IN2015DN00194A (https=) |
| NZ (1) | NZ629701A (https=) |
| SG (1) | SG11201408489PA (https=) |
| WO (1) | WO2013188912A1 (https=) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3170362B2 (ja) | 1992-09-30 | 2001-05-28 | 株式会社リコー | 流体の流量測定装置 |
| AU2011319755B2 (en) | 2010-10-27 | 2017-02-23 | President And Fellows Of Harvard College | Compositions of toehold primer duplexes and methods of use |
| JP2014531203A (ja) * | 2011-09-09 | 2014-11-27 | スピーデクス ピーティーワイ リミテッド | 核酸酵素基質 |
| US9476090B2 (en) | 2013-05-21 | 2016-10-25 | Stc.Unm | Signal propagation biomolecules, devices and methods |
| EP4245859A3 (en) | 2014-03-11 | 2023-11-08 | President and Fellows of Harvard College | High-throughput and highly multiplexed imaging with programmable nucleic acid probes |
| GB201415674D0 (en) * | 2014-09-04 | 2014-10-22 | Moorlodge Biotech Ventures Ltd | Nucleic acid analysis |
| ES2891085T3 (es) | 2015-01-30 | 2022-01-26 | Harvard College | Obtención de imágenes sin microscopio |
| CN116949140A (zh) * | 2016-02-17 | 2023-10-27 | 哈佛学院院长及董事 | 分子编程工具 |
| CN109923213B (zh) | 2016-09-20 | 2023-02-28 | 哈佛学院院长及董事 | 分子验证系统 |
| US10934162B2 (en) * | 2016-11-15 | 2021-03-02 | The Governors Of The University Of Alberta | MicroRNA initiated DNAzyme motor operating in living cells |
| EP3568492B1 (en) | 2017-01-10 | 2025-01-01 | President and Fellows of Harvard College | Multiplexed signal amplification |
| US20200299754A1 (en) * | 2017-04-11 | 2020-09-24 | Speedx Pty Ltd | Detection cascades |
| US20200048691A1 (en) * | 2017-04-17 | 2020-02-13 | Montana State University | Switch-like isothermal dna amplification demonstrating a non-linear amplification rate |
| CN107870242B (zh) * | 2017-10-12 | 2020-02-21 | 广东省生态环境技术研究所 | 一种基于核酸适体的荧光检测试剂盒 |
| CN107663530B (zh) * | 2017-11-10 | 2020-07-03 | 中国海洋大学 | 一种单链核酸检测试剂盒、方法及其应用 |
| CN111630179B (zh) | 2018-01-26 | 2024-07-19 | 哈佛学院院长及董事 | 邻近检测方法和组合物 |
| CN112189055B (zh) | 2018-03-22 | 2024-07-19 | 哈佛学院院长及董事 | 用于分子认证的方法和组合物 |
| CN108642137B (zh) * | 2018-05-21 | 2021-11-30 | 福州大学 | 一种利用回文锁式探针检测肿瘤生物标志物的方法 |
| CN109055609B (zh) * | 2018-08-08 | 2021-10-15 | 临沂大学 | 基于t4 dna聚合酶的西瓜花叶病毒检测传感器及其组装方法 |
| CN109097468A (zh) * | 2018-08-14 | 2018-12-28 | 南通市第人民医院 | Opcml基因启动子甲基化水平的检测试剂盒及其应用 |
| CN109283147B (zh) * | 2018-09-20 | 2021-03-16 | 湖北师范大学 | 一种检测卡那霉素的均相生物传感方法及其应用 |
| WO2020177059A1 (en) * | 2019-03-04 | 2020-09-10 | Nano And Advanced Materials Institute Limited | System and method for detecting heavy metals and bacteria in an analyte |
| CN110607351B (zh) * | 2019-09-20 | 2022-11-01 | 济南大学 | 一种检测尿嘧啶糖基化酶的化学发光生物传感器及其制备方法与应用 |
| WO2021138312A1 (en) * | 2019-12-30 | 2021-07-08 | Ultivue, Inc. | Methods for reducing nonspecific interactions on biological samples |
| CN112029827A (zh) * | 2020-09-04 | 2020-12-04 | 重庆工商大学 | 一种高效率转换率dna纳米探针结构的设计方法 |
| WO2022061166A1 (en) * | 2020-09-17 | 2022-03-24 | Mammoth Biosciences, Inc. | Compositions and methods for detection of a nucleic acid |
| JP2023545038A (ja) * | 2020-10-06 | 2023-10-26 | プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ | 中和標的のシグナルオン検出のための方法、組成物、キット、およびシステム |
| CN113234800B (zh) * | 2021-05-13 | 2023-01-10 | 中山大学 | 一种黄曲霉毒素m1的检测方法及其应用 |
| WO2022271873A2 (en) * | 2021-06-22 | 2022-12-29 | Mammoth Biosciences, Inc. | Programmable nuclease diagnostic device |
| US20230167487A2 (en) | 2021-07-12 | 2023-06-01 | Labsimply, Inc. | Crispr cascade assay |
| US11820983B2 (en) | 2021-12-13 | 2023-11-21 | Labsimply, Inc. | Tuning cascade assay kinetics via molecular design |
| US20230279375A1 (en) * | 2021-12-13 | 2023-09-07 | Labsimply, Inc. | Signal boost cascade assay |
| CN114354912B (zh) * | 2021-12-29 | 2026-01-30 | 东南大学 | 量子点胶束球形核酸传感器及其制备方法和在Pb2+检测中的应用 |
| WO2023225651A2 (en) * | 2022-05-19 | 2023-11-23 | Logicink Corporation | Pre-amplification-free target sequence detection with colormetric readout |
| US12091689B2 (en) | 2022-09-30 | 2024-09-17 | Vedabio, Inc. | Delivery of therapeutics in vivo via a CRISPR-based cascade system |
| US11982677B2 (en) | 2022-10-02 | 2024-05-14 | Vedabio, Inc. | Dimerization screening assays |
| WO2024081156A1 (en) | 2022-10-14 | 2024-04-18 | Vedabio, Inc. | Detection of nucleic acid and non-nucleic acid target molecules |
| WO2024253707A2 (en) | 2023-01-07 | 2024-12-12 | Vedabio, Inc. | Engineered nucleic acid-guided nucleases |
| WO2024151493A1 (en) | 2023-01-10 | 2024-07-18 | Vedabio, Inc. | Sample splitting for multiplexed detection of nucleic acids without amplification |
| CN116286806B (zh) * | 2023-03-21 | 2024-11-29 | 华中科技大学 | 具有催化功能的寡核苷酸、核酸电子器件、逻辑门复合物及电路 |
| WO2025015097A1 (en) * | 2023-07-10 | 2025-01-16 | Arizona Board Of Regents On Behalf Of Arizona State University | Dna-based proteolysis targeting chimera (sdtac) and methods of their use for treating diseases |
| CN116732211B (zh) * | 2023-08-09 | 2023-10-27 | 湖南工程学院 | 基于8-17脱氧核酶与CRISPR-Cas13a反式切割检测牛结核分枝杆菌的探针组及方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424413A (en) * | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
| IL164182A0 (en) * | 1998-03-05 | 2005-12-18 | Johnson & Johnson Res Pty Ltd | Zymogenic nucleic acid detection methods, and related molecules and kits |
| WO2001096541A2 (en) * | 2000-06-15 | 2001-12-20 | Board Of Regents | Allosterically regulated ribozymes |
| JP2004500896A (ja) | 2000-06-21 | 2004-01-15 | ハリス，ロバート，ビー． | ウイルス逆転写酵素活性の測定 |
| US20040106109A1 (en) * | 2001-10-02 | 2004-06-03 | Belly Robert T | Detection of ras mutations |
| EP1814896A4 (en) * | 2004-07-06 | 2008-07-30 | Commercialisation Des Produits | TARGET-RELATED NUCLEIC ACID ADAPTER |
| US20060240462A1 (en) * | 2005-04-21 | 2006-10-26 | Johnson & Johnson Research Pty Limited | Methods for amplification and detection of nucleic acids |
| EP2385141B1 (en) * | 2005-10-07 | 2013-08-07 | SpeeDx Pty Ltd | Multicomponent nucleic acid enzymes and methods for their use |
| US20120101267A1 (en) * | 2005-10-07 | 2012-04-26 | Alison Velyian Todd | Multicomponent nucleic acid enzymes with cleavage, ligase or other activity and methods for their use |
| CA2631881C (en) * | 2005-12-07 | 2015-03-24 | Tibotec Pharmaceuticals Ltd. | Methods, plasmid vectors and primers for assessing hiv viral fitness |
| JP5688507B2 (ja) * | 2006-10-06 | 2015-03-25 | スピーデクス ピーティーワイ リミテッド | 分子スイッチおよびそれらの使用のための方法 |
| MX2009010710A (es) * | 2007-04-05 | 2009-12-08 | Johnson & Johnson Res Pty Ltd | Complejos y enzimas de acido nucleico y metodos para su uso. |
| WO2008122598A2 (en) * | 2007-04-06 | 2008-10-16 | Virco Bvba | Respiratory syncytial virus (rsv) viral load detection assay |
| EP2188394B1 (en) * | 2007-08-13 | 2015-06-24 | University of Strathclyde | Identification of nucleic acid sequences |
| US20110207132A1 (en) * | 2008-08-04 | 2011-08-25 | University Of Maryland | Probes and methods for detecting analytes |
| CN102186997B (zh) * | 2008-08-15 | 2014-12-24 | 卡斯凯德生物体系股份有限公司 | 检测核酸 |
| AU2011331920B2 (en) * | 2010-11-19 | 2014-10-30 | Speedx Pty Ltd | Signal amplification |
| KR101249493B1 (ko) * | 2010-11-23 | 2013-04-01 | 한국과학기술원 | 핵산효소-분자비콘을 이용한 핵산의 검출방법 |
| JP2014531203A (ja) * | 2011-09-09 | 2014-11-27 | スピーデクス ピーティーワイ リミテッド | 核酸酵素基質 |
| CA2863808C (en) * | 2012-02-20 | 2020-07-21 | Speedx Pty Ltd | Methods and oligonucleotides for amplifying and/or detecting nucleic acids |
| US9476090B2 (en) * | 2013-05-21 | 2016-10-25 | Stc.Unm | Signal propagation biomolecules, devices and methods |
-
2013
- 2013-04-03 AU AU2013202354A patent/AU2013202354A1/en not_active Abandoned
- 2013-06-18 JP JP2015517555A patent/JP6336443B2/ja not_active Expired - Fee Related
- 2013-06-18 WO PCT/AU2013/000651 patent/WO2013188912A1/en not_active Ceased
- 2013-06-18 NZ NZ629701A patent/NZ629701A/en not_active IP Right Cessation
- 2013-06-18 IN IN194DEN2015 patent/IN2015DN00194A/en unknown
- 2013-06-18 EP EP13807047.9A patent/EP2861770B1/en active Active
- 2013-06-18 CA CA2876919A patent/CA2876919C/en active Active
- 2013-06-18 CN CN201380042575.3A patent/CN104540965B/zh not_active Expired - Fee Related
- 2013-06-18 AU AU2013277929A patent/AU2013277929B2/en not_active Ceased
- 2013-06-18 US US14/409,375 patent/US9725757B2/en not_active Expired - Fee Related
- 2013-06-18 SG SG11201408489PA patent/SG11201408489PA/en unknown
-
2014
- 2014-12-18 IL IL236363A patent/IL236363A0/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| IL236363A0 (en) | 2015-02-26 |
| WO2013188912A1 (en) | 2013-12-27 |
| CN104540965A (zh) | 2015-04-22 |
| EP2861770A1 (en) | 2015-04-22 |
| AU2013202354A1 (en) | 2014-01-16 |
| CA2876919C (en) | 2021-09-14 |
| AU2013277929B2 (en) | 2015-07-16 |
| CN104540965B (zh) | 2019-06-04 |
| HK1205202A1 (en) | 2015-12-11 |
| IN2015DN00194A (https=) | 2015-06-12 |
| US20160083785A1 (en) | 2016-03-24 |
| JP6336443B2 (ja) | 2018-06-06 |
| NZ629701A (en) | 2016-03-31 |
| EP2861770B1 (en) | 2018-01-31 |
| US9725757B2 (en) | 2017-08-08 |
| JP2015523864A (ja) | 2015-08-20 |
| EP2861770A4 (en) | 2015-12-23 |
| AU2013277929A1 (en) | 2015-01-22 |
| CA2876919A1 (en) | 2013-12-27 |
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