IN2015DN00194A - - Google Patents

Info

Publication number
IN2015DN00194A
IN2015DN00194A IN194DEN2015A IN2015DN00194A IN 2015DN00194 A IN2015DN00194 A IN 2015DN00194A IN 194DEN2015 A IN194DEN2015 A IN 194DEN2015A IN 2015DN00194 A IN2015DN00194 A IN 2015DN00194A
Authority
IN
India
Prior art keywords
methods
compositions
target molecules
relates
present
Prior art date
Application number
Inventor
Simon Mark Bone
Alison Velyian Todd
Timothy Daniel Meehan
Original Assignee
Speedx Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902551A external-priority patent/AU2012902551A0/en
Application filed by Speedx Pty Ltd filed Critical Speedx Pty Ltd
Publication of IN2015DN00194A publication Critical patent/IN2015DN00194A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/9005—Enzymes with nucleic acid structure; e.g. ribozymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The present invention relates to compositions and methods for the detection of target molecules and the amplification of detectable signals generated by detection assays. More specifically the present invention relates to methods utilizing catalytic nucleic acid enzymes to generate and/or amplify a signal indicative of the presence of target molecules (e.g. nucleic acids and proteins) and compositions for use in the methods.
IN194DEN2015 2012-06-18 2013-06-18 IN2015DN00194A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2012902551A AU2012902551A0 (en) 2012-06-18 Target detection and signal amplification
AU2012903462A AU2012903462A0 (en) 2012-08-10 Target detection and signal amplification
AU2013202354A AU2013202354A1 (en) 2012-06-18 2013-04-03 Target detection and signal amplification
PCT/AU2013/000651 WO2013188912A1 (en) 2012-06-18 2013-06-18 Target detection and signal amplification

Publications (1)

Publication Number Publication Date
IN2015DN00194A true IN2015DN00194A (en) 2015-06-12

Family

ID=49767935

Family Applications (1)

Application Number Title Priority Date Filing Date
IN194DEN2015 IN2015DN00194A (en) 2012-06-18 2013-06-18

Country Status (12)

Country Link
US (1) US9725757B2 (en)
EP (1) EP2861770B1 (en)
JP (1) JP6336443B2 (en)
CN (1) CN104540965B (en)
AU (2) AU2013202354A1 (en)
CA (1) CA2876919C (en)
HK (1) HK1205202A1 (en)
IL (1) IL236363A0 (en)
IN (1) IN2015DN00194A (en)
NZ (1) NZ629701A (en)
SG (1) SG11201408489PA (en)
WO (1) WO2013188912A1 (en)

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US9476090B2 (en) 2013-05-21 2016-10-25 Stc.Unm Signal propagation biomolecules, devices and methods
AU2015229406C1 (en) 2014-03-11 2021-01-07 President And Fellows Of Harvard College High-throughput and highly multiplexed imaging with programmable nucleic acid probes
GB201415674D0 (en) * 2014-09-04 2014-10-22 Moorlodge Biotech Ventures Ltd Nucleic acid analysis
CN107208160B (en) 2015-01-30 2023-02-17 哈佛学院院长及董事 No microscope imaging
CN116949140A (en) * 2016-02-17 2023-10-27 哈佛学院院长及董事 Molecular programming tool
CN109923213B (en) 2016-09-20 2023-02-28 哈佛学院院长及董事 Molecular verification system
US10934162B2 (en) * 2016-11-15 2021-03-02 The Governors Of The University Of Alberta MicroRNA initiated DNAzyme motor operating in living cells
EP3568492A4 (en) 2017-01-10 2021-03-17 President and Fellows of Harvard College Multiplexed signal amplification
JP7486951B2 (en) * 2017-04-11 2024-05-20 スピーディックス プロプライアタリー リミティド Detection Cascade
CA3058202A1 (en) * 2017-04-17 2018-10-25 Montana State University Switch-like isothermal dna amplification demonstrating a non-linear amplification rate
CN107870242B (en) * 2017-10-12 2020-02-21 广东省生态环境技术研究所 Fluorescence detection kit based on aptamer
CN107663530B (en) * 2017-11-10 2020-07-03 中国海洋大学 Single-stranded nucleic acid detection kit, method and application thereof
US11981956B2 (en) 2018-01-26 2024-05-14 President And Fellows Of Harvard College Proximity detection methods and compositions
CN108642137B (en) * 2018-05-21 2021-11-30 福州大学 Method for detecting tumor biomarkers by using palindromic padlock probes
CN109055609B (en) * 2018-08-08 2021-10-15 临沂大学 Watermelon mosaic virus detection sensor based on T4 DNA polymerase and assembly method thereof
CN109097468A (en) * 2018-08-14 2018-12-28 南通市第人民医院 The detection kit and its application of OPCML gene promoter methylation level
CN109283147B (en) * 2018-09-20 2021-03-16 湖北师范大学 Homogeneous phase biosensing method for detecting kanamycin and application thereof
WO2020177059A1 (en) * 2019-03-04 2020-09-10 Nano And Advanced Materials Institute Limited System and method for detecting heavy metals and bacteria in an analyte
CN110607351B (en) * 2019-09-20 2022-11-01 济南大学 Chemiluminescence biosensor for detecting uracil glycosylase, and preparation method and application thereof
WO2021138312A1 (en) * 2019-12-30 2021-07-08 Ultivue, Inc. Methods for reducing nonspecific interactions on biological samples
CN112029827A (en) * 2020-09-04 2020-12-04 重庆工商大学 Design method of high-efficiency conversion rate DNA nano probe structure
WO2022061166A1 (en) * 2020-09-17 2022-03-24 Mammoth Biosciences, Inc. Compositions and methods for detection of a nucleic acid
CN113234800B (en) * 2021-05-13 2023-01-10 中山大学 Detection method of aflatoxin M1 and application thereof
WO2022271873A2 (en) * 2021-06-22 2022-12-29 Mammoth Biosciences, Inc. Programmable nuclease diagnostic device
US20230167487A2 (en) 2021-07-12 2023-06-01 Labsimply, Inc. Crispr cascade assay
US11820983B2 (en) 2021-12-13 2023-11-21 Labsimply, Inc. Tuning cascade assay kinetics via molecular design
US20230279375A1 (en) 2021-12-13 2023-09-07 Labsimply, Inc. Signal boost cascade assay
WO2023225651A2 (en) * 2022-05-19 2023-11-23 Logicink Corporation Pre-amplification-free target sequence detection with colormetric readout
US12091689B2 (en) 2022-09-30 2024-09-17 Vedabio, Inc. Delivery of therapeutics in vivo via a CRISPR-based cascade system
WO2024076473A1 (en) 2022-10-02 2024-04-11 Vedabio, Inc. Dimerization screening assays
US11965205B1 (en) 2022-10-14 2024-04-23 Vedabio, Inc. Detection of nucleic acid and non-nucleic acid target molecules
US12091690B2 (en) 2023-01-07 2024-09-17 Vedabio, Inc. Engineered nucleic acid-guided nucleases
WO2024151493A1 (en) 2023-01-10 2024-07-18 Vedabio, Inc. Sample splitting for multiplexed detection of nucleic acids without amplification
CN116286806A (en) * 2023-03-21 2023-06-23 华中科技大学 Oligonucleotide with catalytic function, nucleic acid electronic device, logic gate complex and circuit
CN116732211B (en) * 2023-08-09 2023-10-27 湖南工程学院 Probe set and method for detecting mycobacterium bovis based on 8-17 deoxyribozyme and CRISPR-Cas13a trans-cleavage

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Also Published As

Publication number Publication date
NZ629701A (en) 2016-03-31
US20160083785A1 (en) 2016-03-24
US9725757B2 (en) 2017-08-08
AU2013277929A1 (en) 2015-01-22
JP2015523864A (en) 2015-08-20
EP2861770A1 (en) 2015-04-22
CN104540965A (en) 2015-04-22
EP2861770A4 (en) 2015-12-23
EP2861770B1 (en) 2018-01-31
WO2013188912A1 (en) 2013-12-27
CA2876919A1 (en) 2013-12-27
AU2013277929B2 (en) 2015-07-16
HK1205202A1 (en) 2015-12-11
SG11201408489PA (en) 2015-01-29
CA2876919C (en) 2021-09-14
IL236363A0 (en) 2015-02-26
AU2013202354A1 (en) 2014-01-16
CN104540965B (en) 2019-06-04
JP6336443B2 (en) 2018-06-06

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