SG11201406347TA - Humanized tau antibody - Google Patents

Humanized tau antibody

Info

Publication number
SG11201406347TA
SG11201406347TA SG11201406347TA SG11201406347TA SG11201406347TA SG 11201406347T A SG11201406347T A SG 11201406347TA SG 11201406347T A SG11201406347T A SG 11201406347TA SG 11201406347T A SG11201406347T A SG 11201406347TA SG 11201406347T A SG11201406347T A SG 11201406347TA
Authority
SG
Singapore
Prior art keywords
tau antibody
humanized tau
humanized
antibody
tau
Prior art date
Application number
SG11201406347TA
Other languages
English (en)
Inventor
Andrea Pfeifer
Andreas Muhs
Maria Pihlgren
Oskar Adolfsson
Fred Van Leuven
Gai Ayalon
Cara Danielle Marie Di
Isidro Hotzel
Original Assignee
Ac Immune Sa
Univ Leuven Kath
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa, Univ Leuven Kath, Genentech Inc filed Critical Ac Immune Sa
Publication of SG11201406347TA publication Critical patent/SG11201406347TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
SG11201406347TA 2012-04-05 2013-03-15 Humanized tau antibody SG11201406347TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261620880P 2012-04-05 2012-04-05
PCT/US2013/032341 WO2013151762A1 (fr) 2012-04-05 2013-03-15 Anticorps tau humanisé

Publications (1)

Publication Number Publication Date
SG11201406347TA true SG11201406347TA (en) 2014-11-27

Family

ID=48048231

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406347TA SG11201406347TA (en) 2012-04-05 2013-03-15 Humanized tau antibody

Country Status (16)

Country Link
US (1) US9657091B2 (fr)
EP (1) EP2834270B1 (fr)
JP (1) JP6293731B2 (fr)
KR (1) KR102132041B1 (fr)
CN (1) CN104520322B (fr)
AR (1) AR092818A1 (fr)
AU (1) AU2013243861A1 (fr)
BR (1) BR112014024769A2 (fr)
CA (1) CA2869438C (fr)
HK (1) HK1209137A1 (fr)
IL (1) IL234942A0 (fr)
MX (1) MX356800B (fr)
RU (1) RU2644242C2 (fr)
SG (1) SG11201406347TA (fr)
TW (1) TW201400505A (fr)
WO (1) WO2013151762A1 (fr)

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TW202136296A (zh) 2014-06-27 2021-10-01 美商Ｃ２Ｎ醫療診斷有限責任公司 人類化抗-tau抗體
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Also Published As

Publication number Publication date
CA2869438A1 (fr) 2013-10-10
JP2015521158A (ja) 2015-07-27
KR102132041B1 (ko) 2020-07-09
US20150175682A1 (en) 2015-06-25
HK1209137A1 (en) 2016-03-24
CN104520322B (zh) 2019-11-15
RU2644242C2 (ru) 2018-02-08
IL234942A0 (en) 2014-12-31
CN104520322A (zh) 2015-04-15
EP2834270B1 (fr) 2019-10-30
KR20150003274A (ko) 2015-01-08
BR112014024769A2 (pt) 2017-12-12
MX2014011958A (es) 2015-05-11
JP6293731B2 (ja) 2018-03-14
RU2014144331A (ru) 2016-05-27
WO2013151762A1 (fr) 2013-10-10
EP2834270A1 (fr) 2015-02-11
US9657091B2 (en) 2017-05-23
MX356800B (es) 2018-06-13
AR092818A1 (es) 2015-05-06
CA2869438C (fr) 2021-08-17
AU2013243861A1 (en) 2014-10-23
TW201400505A (zh) 2014-01-01

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