SG10202008244TA - Improved muconic acid production from genetically engineered microorganisms - Google Patents
Improved muconic acid production from genetically engineered microorganismsInfo
- Publication number
- SG10202008244TA SG10202008244TA SG10202008244TA SG10202008244TA SG10202008244TA SG 10202008244T A SG10202008244T A SG 10202008244TA SG 10202008244T A SG10202008244T A SG 10202008244TA SG 10202008244T A SG10202008244T A SG 10202008244TA SG 10202008244T A SG10202008244T A SG 10202008244TA
- Authority
- SG
- Singapore
- Prior art keywords
- improved
- genetically engineered
- acid production
- muconic acid
- engineered microorganisms
- Prior art date
Links
- TXXHDPDFNKHHGW-UHFFFAOYSA-N muconic acid Chemical compound OC(=O)C=CC=CC(O)=O TXXHDPDFNKHHGW-UHFFFAOYSA-N 0.000 title 2
- TXXHDPDFNKHHGW-CCAGOZQPSA-N Muconic acid Natural products OC(=O)\C=C/C=C\C(O)=O TXXHDPDFNKHHGW-CCAGOZQPSA-N 0.000 title 1
- 244000005700 microbiome Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
- C12Y113/11—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of two atoms of oxygen (1.13.11)
- C12Y113/11001—Catechol 1,2-dioxygenase (1.13.11.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y202/00—Transferases transferring aldehyde or ketonic groups (2.2)
- C12Y202/01—Transketolases and transaldolases (2.2.1)
- C12Y202/01001—Transketolase (2.2.1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01054—3-Deoxy-7-phosphoheptulonate synthase (2.5.1.54)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y401/00—Carbon-carbon lyases (4.1)
- C12Y401/01—Carboxy-lyases (4.1.1)
- C12Y401/01063—Protocatechuate decarboxylase (4.1.1.63)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01118—3-Dehydroshikimate dehydratase (4.2.1.118)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
- C12Y402/03004—3-Dehydroquinate synthase (4.2.3.4)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662302558P | 2016-03-02 | 2016-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202008244TA true SG10202008244TA (en) | 2020-10-29 |
Family
ID=59744431
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202008244TA SG10202008244TA (en) | 2016-03-02 | 2017-03-01 | Improved muconic acid production from genetically engineered microorganisms |
| SG11201807544WA SG11201807544WA (en) | 2016-03-02 | 2017-03-01 | Improved muconic acid production from genetically engineered microorganisms |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201807544WA SG11201807544WA (en) | 2016-03-02 | 2017-03-01 | Improved muconic acid production from genetically engineered microorganisms |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20200181658A1 (ko) |
| EP (1) | EP3423563B1 (ko) |
| JP (1) | JP7437116B2 (ko) |
| KR (2) | KR20190003939A (ko) |
| CN (1) | CN109415684B (ko) |
| ES (1) | ES2947938T3 (ko) |
| SG (2) | SG10202008244TA (ko) |
| WO (1) | WO2017151811A1 (ko) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11518975B2 (en) | 2018-04-30 | 2022-12-06 | Alliance For Sustainable Energy, Llc | Engineered microorganisms for the production of intermediates and final products |
| JP2021524230A (ja) * | 2018-05-15 | 2021-09-13 | デューク ユニバーシティ | アッカーマンシア種の遺伝子操作のためのシステムおよび方法 |
| WO2020080467A1 (ja) * | 2018-10-17 | 2020-04-23 | 国立大学法人弘前大学 | ムコン酸産生形質転換微生物及びその利用 |
| CN112300973B (zh) * | 2019-08-02 | 2022-06-24 | 南京理工大学 | 以苯丙氨酰-tRNA合成酶基因突变体为反向筛选标记的红球菌基因编辑方法 |
| CN112300972B (zh) * | 2019-08-02 | 2023-06-30 | 南京理工大学 | 以木质素为原料生产粘糠酸的基因工程菌 |
| CN111004761A (zh) * | 2019-12-02 | 2020-04-14 | 天津科技大学 | 一种l-酪氨酸基因工程菌及其生产l-酪氨酸的方法和应用 |
| WO2021110993A1 (en) * | 2019-12-04 | 2021-06-10 | Synbionik Gmbh | An efficient shuttle vector system for the expression of heterologous and homologous proteins for the genus zymomonas |
| CN112266892B (zh) * | 2020-10-21 | 2021-10-08 | 中国科学院天津工业生物技术研究所 | AroG的突变体及其在产氨基酸基因工程菌中的应用 |
| CN112961878B (zh) * | 2021-03-08 | 2023-04-25 | 昆明理工大学 | 一种植物乳杆菌的基因在叶酸生物生成中的应用 |
| CN114540396A (zh) * | 2022-02-24 | 2022-05-27 | 天津大学 | 希瓦氏菌株中葡萄糖代谢通路的构建方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57170184A (en) | 1980-07-18 | 1982-10-20 | Unisearch Ltd | Mutant of e. coli and production of phenylalanine |
| US4588688A (en) | 1981-07-27 | 1986-05-13 | Celanese Corporation | Process for the production of muconic acid |
| US4608338A (en) | 1982-06-10 | 1986-08-26 | Celanese Corporation | Process for bioconversion-product recovery |
| US4480034A (en) | 1982-06-10 | 1984-10-30 | Celanese Corporation | Continuous fermentation process and bioconversion-product recovery |
| US4535059A (en) | 1983-01-13 | 1985-08-13 | Celanese Corporation | Muconic acid productivity by a stabilized mutant microorganism population |
| JPS6090771A (ja) | 1983-10-26 | 1985-05-21 | Tokyo Electric Co Ltd | インクドツトプリンタ− |
| US4833078A (en) | 1984-06-22 | 1989-05-23 | Celgene Corporation | Semi-continuous fermentation process for aromatic hydrocarbon bioconversion |
| US4968612A (en) | 1984-07-27 | 1990-11-06 | Celgene Corporation | Continuous fermentation process for aromatic hydrocarbon bioconversion |
| JPS61247392A (ja) | 1985-02-04 | 1986-11-04 | エンジニツクス インコ−ポレ−テツド | ２種またはより多くのアミノ酸を同時に産生できる組換え微生物 |
| US4753883A (en) | 1986-05-07 | 1988-06-28 | Biotechnica International, Inc. | Enzyme deregulation |
| US5168056A (en) | 1991-02-08 | 1992-12-01 | Purdue Research Foundation | Enhanced production of common aromatic pathway compounds |
| US5272073A (en) | 1992-06-30 | 1993-12-21 | Purdue Research Foundation | Biocatalytic synthesis of catechol from glucose |
| DE4232468A1 (de) | 1992-09-28 | 1994-03-31 | Consortium Elektrochem Ind | Mikroorganismen für die Produktion von Tryptophan und Verfahren zu ihrer Herstellung |
| US5487987A (en) | 1993-09-16 | 1996-01-30 | Purdue Research Foundation | Synthesis of adipic acid from biomass-derived carbon sources |
| WO1996034961A1 (en) | 1995-05-05 | 1996-11-07 | Genencor International, Inc. | Application of glucose transport mutants for production of aromatic pathway compounds |
| US6210937B1 (en) | 1997-04-22 | 2001-04-03 | Bechtel Bwxt Idaho, Llc | Development of genetically engineered bacteria for production of selected aromatic compounds |
| US6600077B1 (en) | 1999-01-29 | 2003-07-29 | Board Of Trustees Operating Michigan State University | Biocatalytic synthesis of quinic acid and conversion to hydroquinone |
| US6613552B1 (en) | 1999-01-29 | 2003-09-02 | Board Of Trustees Operating Michigan State University | Biocatalytic synthesis of shikimic acid |
| JP2002105641A (ja) | 2000-10-03 | 2002-04-10 | Murakami Corp | 複合材およびその製造方法 |
| JP4229700B2 (ja) | 2001-01-19 | 2009-02-25 | ビーエーエスエフ ソシエタス・ヨーロピア | パントテネートの産生増強のための微生物と方法 |
| US7790431B2 (en) | 2003-09-24 | 2010-09-07 | Board Of Trustees Operating Michigan State University | Methods and materials for the production of shikimic acid |
| KR101142885B1 (ko) | 2003-12-15 | 2012-05-10 | 씨제이제일제당 (주) | 트립토판 생합성 관련 변이유전자를 함유한 대장균 변이주및 이를 이용한 트립토판 제조방법 |
| WO2007020295A2 (en) | 2005-08-18 | 2007-02-22 | Basf Ag | Microorganisms with increased efficiency for methionine synthesis |
| WO2010148049A2 (en) | 2009-06-16 | 2010-12-23 | Draths Corporation | Preparation of trans, trans muconic acid and trans, trans muconates |
| DK2462221T3 (en) | 2009-08-05 | 2017-05-22 | Genomatica Inc | SEMISYNTHETIC TEREPHTHALIC ACID BY MICRO-ORGANISMS PRODUCING MUCONIC ACID |
| KR20120103645A (ko) | 2009-11-18 | 2012-09-19 | 미리안트 코포레이션 | 유기산들을 생산하는 대장균의 대사적 진화 |
| KR20160114184A (ko) | 2009-11-18 | 2016-10-04 | 미리안트 코포레이션 | 화합물들의 효과적인 생산을 위한 미생물 엔지니어링 |
| WO2011085311A1 (en) | 2010-01-08 | 2011-07-14 | Draths Corporation | Methods for producing isomers of muconic acid and muconate salts |
| MY170513A (en) | 2010-12-13 | 2019-08-08 | Ptt Global Chemical Public Co Ltd | Method of producing succinic acid and other chemicals using sucrose-containing feedstock |
| KR20160116352A (ko) | 2011-07-22 | 2016-10-07 | 미리안트 코포레이션 | 유기산으로의 글리세롤의 발효 |
| CN107177540A (zh) * | 2012-01-30 | 2017-09-19 | 麦兰特公司 | 从经基因改造的微生物生产黏康酸 |
| JP2015528312A (ja) * | 2012-09-14 | 2015-09-28 | ミリアント・コーポレイションＭｙｒｉａｎｔ Ｃｏｒｐｏｒａｔｉｏｎ | 低ｐＨ条件下での発酵による有機酸の生産 |
| CN103667166A (zh) * | 2012-09-21 | 2014-03-26 | 天津工业生物技术研究所 | 一株生产己二酸前体物顺,顺-粘康酸的大肠埃希氏菌及应用 |
| CN104099284B (zh) * | 2014-07-01 | 2018-12-04 | 江南大学 | 一株以葡萄糖为底物合成粘康酸的大肠杆菌工程菌 |
| US10017792B2 (en) | 2014-07-18 | 2018-07-10 | Alliance For Sustainable Energy, Llc | Biomass conversion to fuels and chemicals |
-
2017
- 2017-03-01 SG SG10202008244TA patent/SG10202008244TA/en unknown
- 2017-03-01 WO PCT/US2017/020263 patent/WO2017151811A1/en active Application Filing
- 2017-03-01 ES ES17760744T patent/ES2947938T3/es active Active
- 2017-03-01 EP EP17760744.7A patent/EP3423563B1/en active Active
- 2017-03-01 JP JP2018545971A patent/JP7437116B2/ja active Active
- 2017-03-01 KR KR1020187028248A patent/KR20190003939A/ko not_active IP Right Cessation
- 2017-03-01 SG SG11201807544WA patent/SG11201807544WA/en unknown
- 2017-03-01 CN CN201780026997.XA patent/CN109415684B/zh active Active
- 2017-03-01 US US16/081,504 patent/US20200181658A1/en not_active Abandoned
- 2017-03-01 KR KR1020237044654A patent/KR20240005196A/ko active Application Filing
-
2021
- 2021-05-21 US US17/326,643 patent/US11685938B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20200181658A1 (en) | 2020-06-11 |
| US11685938B2 (en) | 2023-06-27 |
| JP7437116B2 (ja) | 2024-02-22 |
| EP3423563A1 (en) | 2019-01-09 |
| KR20190003939A (ko) | 2019-01-10 |
| EP3423563A4 (en) | 2019-10-16 |
| US20210277429A1 (en) | 2021-09-09 |
| JP2019506886A (ja) | 2019-03-14 |
| SG11201807544WA (en) | 2018-09-27 |
| WO2017151811A1 (en) | 2017-09-08 |
| CN109415684A (zh) | 2019-03-01 |
| EP3423563B1 (en) | 2023-05-24 |
| CN109415684B (zh) | 2022-06-07 |
| ES2947938T3 (es) | 2023-08-24 |
| KR20240005196A (ko) | 2024-01-11 |
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