SG10202005315SA - Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist - Google Patents

Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist

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Publication number
SG10202005315SA
SG10202005315SA SG10202005315SA SG10202005315SA SG10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA
Authority
SG
Singapore
Prior art keywords
agent
combining
treating
receptor agonist
diseases associated
Prior art date
Application number
SG10202005315SA
Other languages
English (en)
Inventor
Heiichiro Udono
Shingo Eikawa
Shin-Ichi Toyooka
Original Assignee
Nat Univ Corporation Okayama Univ
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Corporation Okayama Univ, Ono Pharmaceutical Co filed Critical Nat Univ Corporation Okayama Univ
Publication of SG10202005315SA publication Critical patent/SG10202005315SA/en

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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
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  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Rehabilitation Therapy (AREA)
  • Hospice & Palliative Care (AREA)
SG10202005315SA 2014-08-19 2015-08-17 Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist SG10202005315SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014166593 2014-08-19
JP2015085556 2015-04-20

Publications (1)

Publication Number Publication Date
SG10202005315SA true SG10202005315SA (en) 2020-07-29

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SG10202005315SA SG10202005315SA (en) 2014-08-19 2015-08-17 Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist
SG11201700978SA SG11201700978SA (en) 2014-08-19 2015-08-17 Method for enhancing immune cell function and method for assessing immune cell multifunctionality

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US (2) US20170231929A1 (es)
EP (2) EP3232199B1 (es)
JP (3) JP6629211B2 (es)
KR (1) KR20170042778A (es)
CN (1) CN107148274A (es)
AU (1) AU2015304448B2 (es)
BR (1) BR112017002807A2 (es)
CA (1) CA2958573A1 (es)
ES (1) ES2915849T3 (es)
IL (1) IL250639B (es)
MX (1) MX2017002134A (es)
PH (1) PH12017500224B1 (es)
RU (2) RU2020127099A (es)
SG (2) SG10202005315SA (es)
WO (1) WO2016027764A1 (es)

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LT3081576T (lt) 2013-12-12 2019-10-25 Shanghai hengrui pharmaceutical co ltd Pd-1 antikūnas, antigeną surišantis jo fragmentas ir jų medicininis pritaikomumas
MX2019003683A (es) 2016-10-11 2019-08-22 Agenus Inc Anticuerpos anti gen 3 de activación linfocítica (lag 3 ) y métodos para usarlos.
CN107082812B (zh) 2017-03-29 2018-11-13 上海科医联创生物科技有限公司 一种恢复衰竭性免疫细胞功能的融合蛋白及其应用
PT3630112T (pt) * 2017-06-02 2024-04-23 Bayer Healthcare Llc Combinação de regorafenib e nivolumab para tratamento de cancro
WO2019069449A1 (ja) * 2017-10-06 2019-04-11 純児 赤木 測定方法
WO2019124423A1 (ja) * 2017-12-19 2019-06-27 国立大学法人 岡山大学 がんの進行抑制、治療、予防及び/又は再発予防剤
JP2019112353A (ja) * 2017-12-25 2019-07-11 合同会社チューモス 自家腫瘍ワクチン及び免疫誘導方法
WO2019131578A1 (ja) * 2017-12-26 2019-07-04 民男 山内 免疫動態に関する情報を提供する方法、システムおよびプログラム
KR102338992B1 (ko) * 2018-01-05 2021-12-14 지엔티 바이오테크 & 메디컬즈 코포레이션 종양 미세환경 및 면역요법의 조절을 위한 약제학적 조합물 및 방법
WO2019202473A1 (en) * 2018-04-16 2019-10-24 Université de Lausanne Ucp2 inducing agents for the treatment of cancer resistant to immune checkpoint blockade
WO2020118208A1 (en) * 2018-12-07 2020-06-11 Arizona Board Of Regents On Behalf Of The University Of Arizona A method of determining risk for skin cancer development and skin cancer therapeutic prevention by measuring pd-1/pd-l1 signaling pathway members
KR102510381B1 (ko) * 2019-10-16 2023-03-15 한국과학기술원 메트포민을 유효성분으로 포함하는 뇌암의 예방 또는 치료용 면역치료제 조성물
WO2022072745A1 (en) * 2020-10-01 2022-04-07 The Regents Of The University Of California Methods and compositions to treat and prevent viral infections and acute respiratory distress syndrome
CN112791182A (zh) * 2020-12-31 2021-05-14 中山大学 二甲双胍和抗pd-1抗体药物组合物在制备肝癌药物中的应用
CN113421627B (zh) * 2021-05-11 2023-04-07 深圳市罗湖区人民医院 体外评估药物对nk细胞抗衰作用的系统

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