SG11201700978SA - Method for enhancing immune cell function and method for assessing immune cell multifunctionality - Google Patents

Method for enhancing immune cell function and method for assessing immune cell multifunctionality

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Publication number
SG11201700978SA
SG11201700978SA SG11201700978SA SG11201700978SA SG11201700978SA SG 11201700978S A SG11201700978S A SG 11201700978SA SG 11201700978S A SG11201700978S A SG 11201700978SA SG 11201700978S A SG11201700978S A SG 11201700978SA SG 11201700978S A SG11201700978S A SG 11201700978SA
Authority
SG
Singapore
Prior art keywords
immune cell
multifunctionality
assessing
enhancing
cell function
Prior art date
Application number
SG11201700978SA
Inventor
Heiichiro Udono
Shingo Eikawa
Shin-Ichi Toyooka
Original Assignee
Univ Okayama Nat Univ Corp
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Okayama Nat Univ Corp, Ono Pharmaceutical Co filed Critical Univ Okayama Nat Univ Corp
Publication of SG11201700978SA publication Critical patent/SG11201700978SA/en

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    • A—HUMAN NECESSITIES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
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  • Molecular Biology (AREA)
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  • Cell Biology (AREA)
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  • Biochemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Virology (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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SG11201700978SA 2014-08-19 2015-08-17 Method for enhancing immune cell function and method for assessing immune cell multifunctionality SG11201700978SA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014166593 2014-08-19
JP2015085556 2015-04-20
PCT/JP2015/073011 WO2016027764A1 (en) 2014-08-19 2015-08-17 Method for enhancing immune cell function and method for assessing immune cell multifunctionality

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SG11201700978SA true SG11201700978SA (en) 2017-03-30

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SG10202005315SA SG10202005315SA (en) 2014-08-19 2015-08-17 Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist
SG11201700978SA SG11201700978SA (en) 2014-08-19 2015-08-17 Method for enhancing immune cell function and method for assessing immune cell multifunctionality

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US (2) US20170231929A1 (en)
EP (2) EP3232199B1 (en)
JP (3) JP6629211B2 (en)
KR (1) KR20170042778A (en)
CN (1) CN107148274A (en)
AU (1) AU2015304448B2 (en)
BR (1) BR112017002807A2 (en)
CA (1) CA2958573A1 (en)
ES (1) ES2915849T3 (en)
IL (1) IL250639B (en)
MX (1) MX2017002134A (en)
PH (1) PH12017500224A1 (en)
RU (2) RU2731098C2 (en)
SG (2) SG10202005315SA (en)
WO (1) WO2016027764A1 (en)

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ME03527B (en) 2013-12-12 2020-04-20 Shanghai hengrui pharmaceutical co ltd Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof
CN117586403A (en) 2016-10-11 2024-02-23 艾吉纳斯公司 anti-LAG-3 antibodies and methods of use thereof
CN107082812B (en) 2017-03-29 2018-11-13 上海科医联创生物科技有限公司 It is a kind of restore debilitating immune cell function fusion protein and its application
CN110662540B (en) * 2017-06-02 2024-01-26 拜耳医药保健有限责任公司 Combination of regorafenib and a PD-1/PD-L1 (2) inhibitor for the treatment of cancer
JPWO2019069449A1 (en) * 2017-10-06 2019-11-14 純児 赤木 Measuring method
JPWO2019124423A1 (en) * 2017-12-19 2020-10-22 国立大学法人 岡山大学 Cancer progression control, treatment, prevention and / or recurrence prevention agent
JP2019112353A (en) * 2017-12-25 2019-07-11 合同会社チューモス Autologous tumor vaccine and immune induction method
US11959916B2 (en) * 2017-12-26 2024-04-16 Tamio Yamauchi Method, system, and program for supplying immunodynamics-related information
IL264068B2 (en) * 2018-01-05 2023-07-01 Great Novel Therapeutics Biotech & Medicals Corp A combination and pharmaceutical composition comprising an hdac inhibitor, an nsaid in combination with an immune check point inhibitor for use in a method of removing immune suprresion in a tumor microenviroment or stimulating an immune system sgainst cancer cells
WO2019202473A1 (en) * 2018-04-16 2019-10-24 Université de Lausanne Ucp2 inducing agents for the treatment of cancer resistant to immune checkpoint blockade
WO2020118208A1 (en) * 2018-12-07 2020-06-11 Arizona Board Of Regents On Behalf Of The University Of Arizona A method of determining risk for skin cancer development and skin cancer therapeutic prevention by measuring pd-1/pd-l1 signaling pathway members
KR102510381B1 (en) * 2019-10-16 2023-03-15 한국과학기술원 An Immunotherapeutic agent composition for preventing or treating brain cancer comprising metformin as an active reagent
WO2022072745A1 (en) * 2020-10-01 2022-04-07 The Regents Of The University Of California Methods and compositions to treat and prevent viral infections and acute respiratory distress syndrome
CN112791182A (en) * 2020-12-31 2021-05-14 中山大学 Application of pharmaceutical composition of metformin and anti-PD-1 antibody in preparation of liver cancer drugs
CN113421627B (en) * 2021-05-11 2023-04-07 深圳市罗湖区人民医院 System for evaluating anti-aging effect of drug on NK (natural killer) cells in vitro

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