SG10202005315SA - Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist - Google Patents

Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist

Info

Publication number
SG10202005315SA
SG10202005315SA SG10202005315SA SG10202005315SA SG10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA SG 10202005315S A SG10202005315S A SG 10202005315SA
Authority
SG
Singapore
Prior art keywords
agent
combining
treating
receptor agonist
diseases associated
Prior art date
Application number
SG10202005315SA
Inventor
Heiichiro Udono
Shingo Eikawa
Shin-Ichi Toyooka
Original Assignee
Nat Univ Corporation Okayama Univ
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Univ Corporation Okayama Univ, Ono Pharmaceutical Co filed Critical Nat Univ Corporation Okayama Univ
Publication of SG10202005315SA publication Critical patent/SG10202005315SA/en

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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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  • Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
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  • Urology & Nephrology (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Virology (AREA)
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SG10202005315SA 2014-08-19 2015-08-17 Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist SG10202005315SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014166593 2014-08-19
JP2015085556 2015-04-20

Publications (1)

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SG10202005315SA true SG10202005315SA (en) 2020-07-29

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SG11201700978SA SG11201700978SA (en) 2014-08-19 2015-08-17 Method for enhancing immune cell function and method for assessing immune cell multifunctionality
SG10202005315SA SG10202005315SA (en) 2014-08-19 2015-08-17 Agent for treating and/or preventing diseases associated with immune abnormalities by combining biguanide antidiabetic drug with immunosuppressive factor blocking agent or costimulatory receptor agonist

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EP (2) EP3232199B1 (en)
JP (3) JP6629211B2 (en)
KR (1) KR20170042778A (en)
CN (1) CN107148274A (en)
AU (1) AU2015304448B2 (en)
BR (1) BR112017002807A2 (en)
CA (1) CA2958573A1 (en)
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PH (1) PH12017500224A1 (en)
RU (2) RU2020127099A (en)
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JP2019112353A (en) * 2017-12-25 2019-07-11 合同会社チューモス Autologous tumor vaccine and immune induction method
JP7329840B2 (en) * 2017-12-26 2023-08-21 民男 山内 Methods, systems and programs for providing information on immune dynamics
AU2019200033B2 (en) * 2018-01-05 2020-09-10 Gnt Biotech & Medicals Corporation A pharmaceutical combination and method for regulation of tumor microenvironment and immunotherapy
WO2019202473A1 (en) * 2018-04-16 2019-10-24 Université de Lausanne Ucp2 inducing agents for the treatment of cancer resistant to immune checkpoint blockade
US20220017969A1 (en) * 2018-12-07 2022-01-20 Arizona Board Of Regents On Behalf Of The University Of Arizona A method of determining risk for skin cancer development and skin cancer therapeutic prevention by measuring pd-1/pd-l1 signaling pathway members
KR102510381B1 (en) * 2019-10-16 2023-03-15 한국과학기술원 An Immunotherapeutic agent composition for preventing or treating brain cancer comprising metformin as an active reagent
WO2022072745A1 (en) * 2020-10-01 2022-04-07 The Regents Of The University Of California Methods and compositions to treat and prevent viral infections and acute respiratory distress syndrome
CN112791182A (en) * 2020-12-31 2021-05-14 中山大学 Application of pharmaceutical composition of metformin and anti-PD-1 antibody in preparation of liver cancer drugs
CN113421627B (en) * 2021-05-11 2023-04-07 深圳市罗湖区人民医院 System for evaluating anti-aging effect of drug on NK (natural killer) cells in vitro

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