SG10201804469RA - Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods - Google Patents
Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methodsInfo
- Publication number
- SG10201804469RA SG10201804469RA SG10201804469RA SG10201804469RA SG10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA SG 10201804469R A SG10201804469R A SG 10201804469RA
- Authority
- SG
- Singapore
- Prior art keywords
- variants
- methods
- timp
- compositions
- tissue inhibitor
- Prior art date
Links
- 102000005876 Tissue Inhibitor of Metalloproteinases Human genes 0.000 title abstract 2
- 108010005246 Tissue Inhibitor of Metalloproteinases Proteins 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000005406 Tissue Inhibitor of Metalloproteinase-3 Human genes 0.000 title 1
- 108010031429 Tissue Inhibitor of Metalloproteinase-3 Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361782613P | 2013-03-14 | 2013-03-14 | |
| US201361798160P | 2013-03-15 | 2013-03-15 | |
| US201361802988P | 2013-03-18 | 2013-03-18 | |
| US201461940673P | 2014-02-17 | 2014-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201804469RA true SG10201804469RA (en) | 2018-06-28 |
Family
ID=50473803
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201804469RA SG10201804469RA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
| SG11201507524TA SG11201507524TA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507524TA SG11201507524TA (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10189890B2 (fr) |
| EP (1) | EP2970407B1 (fr) |
| JP (5) | JP2016513666A (fr) |
| KR (1) | KR102258564B1 (fr) |
| CN (2) | CN105531285B (fr) |
| AP (1) | AP2015008729A0 (fr) |
| AU (5) | AU2014236683B2 (fr) |
| BR (1) | BR112015022491A2 (fr) |
| CA (1) | CA2906053C (fr) |
| CL (1) | CL2015002663A1 (fr) |
| EA (1) | EA034200B1 (fr) |
| HK (1) | HK1219959A1 (fr) |
| IL (1) | IL241246B (fr) |
| MX (1) | MX2015012891A (fr) |
| PE (1) | PE20151894A1 (fr) |
| PH (1) | PH12015502059A1 (fr) |
| SG (2) | SG10201804469RA (fr) |
| TN (1) | TN2015000423A1 (fr) |
| TW (3) | TWI733138B (fr) |
| WO (1) | WO2014152012A2 (fr) |
| ZA (2) | ZA201506746B (fr) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105764523A (zh) * | 2013-09-18 | 2016-07-13 | 詹姆斯库克大学 | 抗炎蛋白及使用方法 |
| BR112016025852B1 (pt) | 2014-05-07 | 2022-11-01 | Amgen Inc | Dispositivo de injeção para aplicação de fármaco |
| KR102416904B1 (ko) | 2014-06-03 | 2022-07-04 | 암겐 인코포레이티드 | 약물 전달 디바이스에 의해 수집된 데이터를 원격으로 프로세싱하기 위한 시스템들 및 방법들 |
| CA2956726C (fr) * | 2014-08-27 | 2023-06-06 | Amgen Inc. | Variants d'inhibiteur tissulaire de la metalloproteinase de type trois (timp-3), compositions et procedes |
| WO2016061220A2 (fr) | 2014-10-14 | 2016-04-21 | Amgen Inc. | Dispositif d'injection de médicament comportant des témoins visuels et sonores |
| US11357916B2 (en) | 2014-12-19 | 2022-06-14 | Amgen Inc. | Drug delivery device with live button or user interface field |
| CA3069716C (fr) | 2015-02-17 | 2021-11-09 | Amgen Inc. | Dispositif d'administration de medicament a securisation assistee par depression et/ou retour d'informations |
| ES2905870T3 (es) | 2015-02-27 | 2022-04-12 | Amgen Inc | Dispositivo de suministro de fármacos que tiene un mecanismo de protección de aguja con un umbral de resistencia ajustable al movimiento de la protección de aguja |
| WO2017039786A1 (fr) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Adaptateur d'ensemble de seringue pour une seringue |
| WO2017100501A1 (fr) | 2015-12-09 | 2017-06-15 | Amgen Inc. | Auto-injecteur avec capuchon de signalisation |
| WO2017120178A1 (fr) | 2016-01-06 | 2017-07-13 | Amgen Inc. | Auto-injecteur pourvu d'une électronique de signalisation |
| DK3429663T3 (da) | 2016-03-15 | 2020-09-28 | Amgen Inc | Reduktion af sandsynligheden for glasbrud i anordninger til indgivelse af lægemidler |
| WO2017189089A1 (fr) | 2016-04-29 | 2017-11-02 | Amgen Inc. | Dispositif d'administration de médicament avec étiquette de messagerie |
| US11389588B2 (en) | 2016-05-02 | 2022-07-19 | Amgen Inc. | Syringe adapter and guide for filling an on-body injector |
| AU2017263558B2 (en) | 2016-05-13 | 2022-12-22 | Amgen Inc. | Vial sleeve assembly |
| WO2017200989A1 (fr) | 2016-05-16 | 2017-11-23 | Amgen Inc. | Chiffrement de données dans des dispositifs médicaux à capacité de calcul limitée |
| EP3465124A1 (fr) | 2016-06-03 | 2019-04-10 | Amgen Inc. | Appareils et procédés d'essai au choc destinés aux dispositifs d'administration de médicaments |
| US11285266B2 (en) | 2016-07-01 | 2022-03-29 | Amgen Inc. | Drug delivery device having minimized risk of component fracture upon impact events |
| WO2018034784A1 (fr) | 2016-08-17 | 2018-02-22 | Amgen Inc. | Dispositif d'administration de médicament avec détection de positionnement. |
| WO2018081234A1 (fr) | 2016-10-25 | 2018-05-03 | Amgen Inc. | Injecteur porté sur le corps |
| MX2019008432A (es) | 2017-01-17 | 2019-11-18 | Amgen Inc | Dispositivos de inyeccion y metodos relacionados de uso y ensamblaje. |
| AU2018221351B2 (en) | 2017-02-17 | 2023-02-23 | Amgen Inc. | Insertion mechanism for drug delivery device |
| US11752258B2 (en) | 2017-02-17 | 2023-09-12 | Amgen Inc. | Drug delivery device with sterile fluid flowpath and related method of assembly |
| CA3050927A1 (fr) | 2017-03-06 | 2018-09-13 | Brian Stonecipher | Dispositif d'administration de medicaments dote d'une fonction de prevention d'activation |
| US11571511B2 (en) | 2017-03-07 | 2023-02-07 | Amgen Inc. | Insertion mechanism and method of inserting a needle of a drug delivery device |
| AU2018230486B2 (en) | 2017-03-09 | 2023-05-11 | Amgen Inc. | Insertion mechanism for drug delivery device |
| HUE063805T2 (hu) | 2017-03-28 | 2024-01-28 | Amgen Inc | Dugattyúrúd és fecskendõ összeállító rendszer és eljárás |
| EP3634539A1 (fr) | 2017-06-08 | 2020-04-15 | Amgen Inc. | Ensemble de seringue d'un appareil d'administration de médicament et procédé d'assemblage |
| JP7200134B2 (ja) | 2017-06-08 | 2023-01-06 | アムジエン・インコーポレーテツド | トルク駆動式薬物送達デバイス |
| MX2019015472A (es) | 2017-06-22 | 2020-02-19 | Amgen Inc | Reduccion del impacto/choque de la activacion del mecanismo. |
| JP7475860B2 (ja) | 2017-06-23 | 2024-04-30 | アムジエン・インコーポレーテツド | スイッチアセンブリにより起動されるキャップを含む電子薬物送達デバイス |
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| US6562596B1 (en) * | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
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| JP5025045B2 (ja) * | 2001-02-02 | 2012-09-12 | マルホ株式会社 | 多硫酸化多糖類によるｔｉｍｐ産生の亢進 |
| WO2004085617A2 (fr) | 2003-03-21 | 2004-10-07 | The Cleveland Clinic Foundation | Inhibiteur de vegf en tant que timp3 |
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| EP2268807A2 (fr) * | 2008-04-21 | 2011-01-05 | Novo Nordisk A/S | Facteur ix de coagulation humain hyperglycosylé |
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| JP2013500987A (ja) * | 2009-07-31 | 2013-01-10 | アムジェン インコーポレイテッド | ３型メタロプロテイナーゼ組織阻害剤（ｔｉｍｐ−３）に結合するポリペプチド、組成物および方法 |
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