AP2015008729A0 - Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods - Google Patents
Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methodsInfo
- Publication number
- AP2015008729A0 AP2015008729A0 AP2015008729A AP2015008729A AP2015008729A0 AP 2015008729 A0 AP2015008729 A0 AP 2015008729A0 AP 2015008729 A AP2015008729 A AP 2015008729A AP 2015008729 A AP2015008729 A AP 2015008729A AP 2015008729 A0 AP2015008729 A0 AP 2015008729A0
- Authority
- AP
- ARIPO
- Prior art keywords
- timp
- variants
- compositions
- methods
- tissue inhibitor
- Prior art date
Links
- 102000005406 Tissue Inhibitor of Metalloproteinase-3 Human genes 0.000 title 1
- 108010031429 Tissue Inhibitor of Metalloproteinase-3 Proteins 0.000 title 1
- 102000005876 Tissue Inhibitor of Metalloproteinases Human genes 0.000 title 1
- 108010005246 Tissue Inhibitor of Metalloproteinases Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8146—Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361782613P | 2013-03-14 | 2013-03-14 | |
| US201361798160P | 2013-03-15 | 2013-03-15 | |
| US201361802988P | 2013-03-18 | 2013-03-18 | |
| US201461940673P | 2014-02-17 | 2014-02-17 | |
| PCT/US2014/026811 WO2014152012A2 (fr) | 2013-03-14 | 2014-03-13 | Variants d'inhibiteur tissulaire de la métalloprotéinase type iii (timp-3), compositions et procédés |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2015008729A0 true AP2015008729A0 (en) | 2015-09-30 |
Family
ID=50473803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2015008729A AP2015008729A0 (en) | 2013-03-14 | 2014-03-13 | Variants of tissue inhibitor of metalloproteinase type three (timp-3), compositions and methods |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US10189890B2 (fr) |
| EP (1) | EP2970407B1 (fr) |
| JP (5) | JP2016513666A (fr) |
| KR (1) | KR102258564B1 (fr) |
| CN (2) | CN111499733A (fr) |
| AP (1) | AP2015008729A0 (fr) |
| AU (5) | AU2014236683B2 (fr) |
| BR (1) | BR112015022491A2 (fr) |
| CA (1) | CA2906053C (fr) |
| CL (1) | CL2015002663A1 (fr) |
| EA (1) | EA034200B1 (fr) |
| HK (1) | HK1219959A1 (fr) |
| IL (1) | IL241246B (fr) |
| MX (1) | MX2015012891A (fr) |
| PE (1) | PE20151894A1 (fr) |
| PH (1) | PH12015502059A1 (fr) |
| SG (2) | SG11201507524TA (fr) |
| TN (1) | TN2015000423A1 (fr) |
| TW (3) | TW201726725A (fr) |
| WO (1) | WO2014152012A2 (fr) |
| ZA (2) | ZA201506746B (fr) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016536343A (ja) * | 2013-09-18 | 2016-11-24 | ジェームス・クック・ユニバーシティー | 抗炎症性のタンパク質及び使用方法 |
| EP3139977B1 (fr) | 2014-05-07 | 2021-02-17 | Amgen Inc. | Auto-injecteur comprenant des éléments de réduction de choc |
| SG11201609966SA (en) | 2014-06-03 | 2016-12-29 | Amgen Inc | Drug delivery system and method of use |
| EA201790470A1 (ru) * | 2014-08-27 | 2017-07-31 | Эмджен Инк. | Варианты тканевого ингибитора металлопротеиназ типа три (тимп-3), композиции и способы |
| MX2021014323A (es) | 2014-10-14 | 2023-02-02 | Amgen Inc | Dispositivo de inyección de fármaco con indicadores visuales y audibles. |
| EP3689394A1 (fr) | 2014-12-19 | 2020-08-05 | Amgen Inc. | Dispositif d'administration de médicaments avec bouton mobile ou panneau d'interface utilisateur |
| EP3556411B1 (fr) | 2015-02-17 | 2021-06-30 | Amgen Inc. | Dispositif d'administration de médicaments avec fixation et/ou de rétroaction assistée(s) sous vide |
| EP3261690B1 (fr) | 2015-02-27 | 2021-12-15 | Amgen Inc. | Dispositif d'administration de médicament ayant un mécanisme de protection d'aiguille présentant un seuil réglable de résistance au mouvement de l'élément de protection d'aiguille |
| WO2017039786A1 (fr) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Adaptateur d'ensemble de seringue pour une seringue |
| US11351308B2 (en) | 2015-12-09 | 2022-06-07 | Amgen Inc. | Auto-injector with signaling cap |
| WO2017120178A1 (fr) | 2016-01-06 | 2017-07-13 | Amgen Inc. | Auto-injecteur pourvu d'une électronique de signalisation |
| ES2814287T3 (es) | 2016-03-15 | 2021-03-26 | Amgen Inc | Reducir la probabilidad de rotura de cristal en dispositivos de administración de fármaco |
| WO2017189089A1 (fr) | 2016-04-29 | 2017-11-02 | Amgen Inc. | Dispositif d'administration de médicament avec étiquette de messagerie |
| US11389588B2 (en) | 2016-05-02 | 2022-07-19 | Amgen Inc. | Syringe adapter and guide for filling an on-body injector |
| WO2017197222A1 (fr) | 2016-05-13 | 2017-11-16 | Amgen Inc. | Ensemble manchon de flacon |
| WO2017200989A1 (fr) | 2016-05-16 | 2017-11-23 | Amgen Inc. | Chiffrement de données dans des dispositifs médicaux à capacité de calcul limitée |
| WO2017209899A1 (fr) | 2016-06-03 | 2017-12-07 | Amgen Inc. | Appareils et procédés d'essai au choc destinés aux dispositifs d'administration de médicaments |
| EP3478342A1 (fr) | 2016-07-01 | 2019-05-08 | Amgen Inc. | Dispositif d'administration de médicament présentant un risque réduit au minimum de fracture de composant lors d'événements d'impact |
| WO2018034784A1 (fr) | 2016-08-17 | 2018-02-22 | Amgen Inc. | Dispositif d'administration de médicament avec détection de positionnement. |
| WO2018081234A1 (fr) | 2016-10-25 | 2018-05-03 | Amgen Inc. | Injecteur porté sur le corps |
| AU2018210301A1 (en) | 2017-01-17 | 2019-08-01 | Amgen Inc. | Injection devices and related methods of use and assembly |
| CA3048520A1 (fr) | 2017-02-17 | 2018-08-23 | Amgen Inc. | Dispositif d'administration de medicament a trajet d'ecoulement de fluide sterile et procede d'assemblage associe |
| US11369736B2 (en) | 2017-02-17 | 2022-06-28 | Amgen Inc. | Cannula insertion and retraction mechanisms |
| JP2020508803A (ja) | 2017-03-06 | 2020-03-26 | アムジエン・インコーポレーテツド | 作動防止特徴部を備える薬物送達デバイス |
| SG11201908058UA (en) | 2017-03-07 | 2019-09-27 | Amgen Inc | Needle insertion by overpressure |
| KR102619150B1 (ko) | 2017-03-09 | 2023-12-27 | 암겐 인코포레이티드 | 약물 전달 장치용 삽입 메커니즘 |
| SI3600491T1 (sl) | 2017-03-28 | 2023-11-30 | Amgen Inc. | Sistem in postopek za sestavljanja droga bata in brizge |
| CN110709121B (zh) | 2017-06-08 | 2022-06-24 | 安进公司 | 扭矩驱动式药物递送装置 |
| AU2018280054B2 (en) | 2017-06-08 | 2023-07-13 | Amgen Inc. | Syringe assembly for a drug delivery device and method of assembly |
| MX2019015472A (es) | 2017-06-22 | 2020-02-19 | Amgen Inc | Reduccion del impacto/choque de la activacion del mecanismo. |
| WO2018237225A1 (fr) | 2017-06-23 | 2018-12-27 | Amgen Inc. | Dispositif électronique d'administration de médicament comprenant un bouchon activé par un ensemble commutateur |
| EP3651832B1 (fr) | 2017-07-14 | 2023-12-13 | Amgen Inc. | Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion |
| MA49626A (fr) | 2017-07-21 | 2020-05-27 | Amgen Inc | Élément d'étanchéité perméable aux gaz pour récipient à médicament et procédés d'assemblage |
| MA49676A (fr) | 2017-07-25 | 2020-06-03 | Amgen Inc | Dispositif d'administration de médicament doté d'un système d'accès à un récipient et procédé d'assemblage associé |
| EP3658203B1 (fr) | 2017-07-25 | 2022-08-31 | Amgen Inc. | Dispositif d'administration de médicament avec module d'engrenage et procédé d'assemblage associé |
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Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6562596B1 (en) | 1993-10-06 | 2003-05-13 | Amgen Inc. | Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods |
| JPH09235300A (ja) * | 1996-02-29 | 1997-09-09 | Fuji Yakuhin Kogyo Kk | ヒトｔｉｍｐ−３及び抗ヒトｔｉｍｐ−３モノクローナル抗体並びにその用途 |
| JP5025045B2 (ja) * | 2001-02-02 | 2012-09-12 | マルホ株式会社 | 多硫酸化多糖類によるｔｉｍｐ産生の亢進 |
| WO2004085617A2 (fr) | 2003-03-21 | 2004-10-07 | The Cleveland Clinic Foundation | Inhibiteur de vegf en tant que timp3 |
| US8431396B2 (en) * | 2003-03-21 | 2013-04-30 | The Cleveland Clinic Foundation | Anti-angiogenic peptides |
| US7641643B2 (en) | 2003-04-15 | 2010-01-05 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
| JP5175178B2 (ja) * | 2005-05-12 | 2013-04-03 | グラクソ グループ リミテッド | ワクチン組成物 |
| JP2009502179A (ja) * | 2005-07-29 | 2009-01-29 | インペリアル イノベーションズ リミテッド | 化合物 |
| US20110137011A1 (en) * | 2008-04-21 | 2011-06-09 | Novo Nordisk A/S | Hyperglycosylated human coagulation factor ix |
| EP2370581B1 (fr) * | 2008-12-04 | 2016-08-03 | CuRNA, Inc. | Traitement de maladies apparentées au facteur de croissance de l'endothélium vasculaire (vegf) par inhibition du transcript antisens naturel du vegf |
| CA2769206A1 (fr) * | 2009-07-31 | 2011-02-03 | Amgen Inc. | Polypeptides qui se lient a un inhibiteur tissulaire de la metalloproteinase de type trois (timp-3), compositions et procedes |
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