SG10201701634PA - Anti - sclerostin antibody crystals and formulations thereof - Google Patents

Anti - sclerostin antibody crystals and formulations thereof

Info

Publication number
SG10201701634PA
SG10201701634PA SG10201701634PA SG10201701634PA SG10201701634PA SG 10201701634P A SG10201701634P A SG 10201701634PA SG 10201701634P A SG10201701634P A SG 10201701634PA SG 10201701634P A SG10201701634P A SG 10201701634PA SG 10201701634P A SG10201701634P A SG 10201701634PA
Authority
SG
Singapore
Prior art keywords
formulations
sclerostin antibody
antibody crystals
crystals
sclerostin
Prior art date
Application number
SG10201701634PA
Other languages
English (en)
Inventor
Christi L Clogston
Twinkle R Christian
Timothy D Osslund
Elisabeth Freeman
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45922852&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201701634P(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SG10201701634PA publication Critical patent/SG10201701634PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201701634PA 2011-03-25 2012-03-23 Anti - sclerostin antibody crystals and formulations thereof SG10201701634PA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161467868P 2011-03-25 2011-03-25

Publications (1)

Publication Number Publication Date
SG10201701634PA true SG10201701634PA (en) 2017-04-27

Family

ID=45922852

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201701634PA SG10201701634PA (en) 2011-03-25 2012-03-23 Anti - sclerostin antibody crystals and formulations thereof
SG2013071733A SG193610A1 (en) 2011-03-25 2012-03-23 Anti - sclerostin antibody crystals and formulations thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013071733A SG193610A1 (en) 2011-03-25 2012-03-23 Anti - sclerostin antibody crystals and formulations thereof

Country Status (24)

Country Link
US (3) US9145457B2 (es)
EP (1) EP2688910B1 (es)
JP (2) JP2014511842A (es)
KR (1) KR20140018315A (es)
CN (1) CN103517920B (es)
AP (1) AP3981A (es)
AR (1) AR085575A1 (es)
AU (1) AU2012236962B2 (es)
BR (1) BR112013024493A2 (es)
CA (1) CA2830538C (es)
CL (1) CL2013002743A1 (es)
CO (1) CO6801637A2 (es)
CR (1) CR20160147A (es)
EA (1) EA029956B1 (es)
IL (1) IL228455A (es)
MA (1) MA35009B1 (es)
MX (1) MX338078B (es)
MY (1) MY170720A (es)
PE (1) PE20140437A1 (es)
SG (2) SG10201701634PA (es)
TN (1) TN2013000378A1 (es)
TW (1) TW201247703A (es)
WO (1) WO2012135035A1 (es)
ZA (2) ZA201307122B (es)

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US7592429B2 (en) * 2005-05-03 2009-09-22 Ucb Sa Sclerostin-binding antibody
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
CA2964470A1 (en) * 2014-10-17 2016-04-21 Amgen Inc. Antibodies directed to angiopoietin-1 and angiopoietin-2 for ocular therapies
AR103726A1 (es) 2015-02-27 2017-05-31 Merck Sharp & Dohme Cristales de anticuerpos monoclonales anti-pd-1 humanos
CN107090443B (zh) * 2016-02-18 2020-12-08 中国农业大学 一种制备稻瘟病菌促分裂原活化蛋白激酶MoMps1晶体的方法
CN105777858B (zh) * 2016-03-22 2019-09-10 东软威特曼生物科技(南京)有限公司 多种抗体的复合稳定剂及其使用方法
KR20190027878A (ko) * 2016-07-13 2019-03-15 리폼 바이오로직스, 엘엘씨 치료 단백질 제제용 안정화 부형제
JP2020502218A (ja) 2016-12-21 2020-01-23 メレオ バイオファーマ 3 リミテッド 骨形成不全症の処置における抗スクレロスチン抗体の使用
JOP20190260A1 (ar) 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
CN110913906A (zh) 2017-05-02 2020-03-24 默沙东公司 抗lag3抗体的制剂和抗lag3抗体与抗pd-1抗体的共制剂
EP3659586B1 (en) 2017-07-27 2023-06-21 Jiangsu Hengrui Medicine Co., Ltd. Sost antibody pharmaceutical composition and uses thereof
CN109112153A (zh) * 2018-09-03 2019-01-01 浙江善测禾骑士生物科技有限公司 一种lpor-y193f突变体蛋白晶体的制备方法
WO2020092233A1 (en) * 2018-10-31 2020-05-07 Merck Sharp & Dohme Corp. Anti-human pd-1 antibody crystals and methods of use thereof
EP3653702A1 (en) * 2018-11-15 2020-05-20 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Crystal structure of a replication protein encoded by a plasmid isolated from a multiple sclerosis patient
CN113444800A (zh) * 2021-06-30 2021-09-28 北京泱深生物信息技术有限公司 基因群作为共预后因子在肾癌预后检测中的应用
CN115804338A (zh) * 2022-12-19 2023-03-17 新疆农业科学院经济作物研究所 一种海岛棉育种方法
CN116375864B (zh) * 2023-05-16 2023-08-08 成都大熊猫繁育研究基地 一种抗大熊猫amh单克隆抗体、杂交瘤细胞株及其应用

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CA2830538A1 (en) 2012-10-04
US20170210792A1 (en) 2017-07-27
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US9145457B2 (en) 2015-09-29
EP2688910A1 (en) 2014-01-29
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CN103517920A (zh) 2014-01-15
BR112013024493A2 (pt) 2018-06-26
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AP3981A (en) 2017-01-05
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