SG10201407938TA - Agents for treating disease - Google Patents
Agents for treating diseaseInfo
- Publication number
- SG10201407938TA SG10201407938TA SG10201407938TA SG10201407938TA SG10201407938TA SG 10201407938T A SG10201407938T A SG 10201407938TA SG 10201407938T A SG10201407938T A SG 10201407938TA SG 10201407938T A SG10201407938T A SG 10201407938TA SG 10201407938T A SG10201407938T A SG 10201407938TA
- Authority
- SG
- Singapore
- Prior art keywords
- agents
- treating disease
- regulatory
- antibodies
- activating
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70514—CD4
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0920944.6A GB0920944D0 (en) | 2009-11-30 | 2009-11-30 | Agents for treating disease |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10201407938TA true SG10201407938TA (en) | 2015-01-29 |
Family
ID=41572903
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2012039442A SG181117A1 (en) | 2009-11-30 | 2010-11-30 | Agents for treating disease |
SG10201407938TA SG10201407938TA (en) | 2009-11-30 | 2010-11-30 | Agents for treating disease |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG2012039442A SG181117A1 (en) | 2009-11-30 | 2010-11-30 | Agents for treating disease |
Country Status (17)
Country | Link |
---|---|
US (1) | US9995733B2 (es) |
EP (1) | EP2470902B1 (es) |
JP (1) | JP5959438B2 (es) |
KR (1) | KR101872746B1 (es) |
CN (1) | CN102687010B (es) |
AU (1) | AU2010323045B2 (es) |
BR (1) | BR112012012911A8 (es) |
CA (1) | CA2781836A1 (es) |
ES (1) | ES2643640T3 (es) |
GB (1) | GB0920944D0 (es) |
IL (1) | IL219956B (es) |
MX (1) | MX347247B (es) |
NZ (1) | NZ600889A (es) |
RU (1) | RU2598719C2 (es) |
SG (2) | SG181117A1 (es) |
WO (1) | WO2011064407A1 (es) |
ZA (1) | ZA201204845B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
EP2471543A1 (en) * | 2010-12-02 | 2012-07-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Tolerance induction or immunosupression to prevent in particular Graft-versus-Host-Disease (GvHD) by short-term pre-incubation of transplanted cell suspensions, tissues or organs coated with ligands to cell surface molecules |
US20140322188A1 (en) | 2013-04-26 | 2014-10-30 | Enzo Biochem, Inc. | Tolerizing treatments for autoimmune disease |
US20170232084A1 (en) | 2013-04-26 | 2017-08-17 | Enzo Biochem Inc. | Immune modulation for the treatment of age-related macular degeneration |
GB201413899D0 (en) | 2014-08-06 | 2014-09-17 | Johnson Matthey Plc | Catalyst and use therof |
CR20170482A (es) * | 2015-04-24 | 2018-03-07 | Viiv Healthcare Uk No 5 Ltd | Polipéptidos dirigidos a la fusión de vih |
US20180126021A1 (en) * | 2016-11-04 | 2018-05-10 | Covidien Lp | Sterilization system and method |
GB202017681D0 (en) | 2020-11-09 | 2020-12-23 | T Balance Therapeutics Gmbh | Anti-CD4 antibody or fragment thereof for medical use |
WO2024144806A1 (en) * | 2022-12-29 | 2024-07-04 | Development Center For Biotechnology | Antibodies specific to transmembrane and coiled-coil domain family 3 and uses thereof |
Family Cites Families (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT90657B (pt) | 1988-05-27 | 1995-03-01 | Ortho Pharma Corp | Processo para a preparacao de peptidos que bloqueiam a ligacao de hiv-1 a proteina cd4 receptora |
JPH0768273B2 (ja) * | 1988-12-02 | 1995-07-26 | カルピス食品工業株式会社 | 抗hivペプチド |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
AU5656890A (en) | 1989-05-02 | 1990-11-29 | Genelabs Incorporated | Chemically modified cd4 peptide fragments having anti-retroviral properties |
US5690933A (en) | 1989-05-31 | 1997-11-25 | Glaxo Wellcome Inc. | Monoclonal antibodies for inducing tolerance |
GB8912497D0 (en) | 1989-05-31 | 1989-07-19 | Cobbold Stephen P | Monoclonal antibodies |
GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
US20020099179A1 (en) | 1989-12-21 | 2002-07-25 | Linda K. Jolliffe | Cdr-grafted antibodies |
US5859205A (en) | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
HUT60768A (en) | 1990-03-16 | 1992-10-28 | Sandoz Ag | Process for producing cd25 fixing molecules |
US7084260B1 (en) | 1996-10-10 | 2006-08-01 | Genpharm International, Inc. | High affinity human antibodies and human antibodies against human antigens |
EP0512112B1 (en) | 1990-11-27 | 1997-05-28 | Biogen, Inc. | Anti cd-4 antibodies blocking hiv-induced syncytia |
US7192584B2 (en) | 1991-03-18 | 2007-03-20 | Centocor, Inc. | Methods of treating psoriasis with anti-TNF antibodies |
US6136310A (en) | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化b−b10 |
US5777085A (en) | 1991-12-20 | 1998-07-07 | Protein Design Labs, Inc. | Humanized antibodies reactive with GPIIB/IIIA |
IL101769A (en) | 1992-05-03 | 2007-02-11 | Yeda Res & Dev | Modulation of TNF receptor action |
US6270766B1 (en) | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
ATE155043T1 (de) | 1992-10-08 | 1997-07-15 | Kennedy Inst Of Rheumatology | Behandlung von autoimmun- und entzundungskrankheiten |
DK0614984T4 (da) | 1993-03-05 | 2010-12-20 | Bayer Healthcare Llc | Humane monoklonale anti-TNF-alfa-antistoffer |
EP0631783A1 (en) | 1993-06-03 | 1995-01-04 | Mitsubishi Chemical Corporation | Antiviral combinations of 2',3'-di-deoxyribonucleosides with 6-benzyl-1-ethoxymethyl-5-substituted uracil derivatives |
JPH09510952A (ja) | 1993-10-06 | 1997-11-04 | ザ ケネディー インスティチュート オブ リューマトロジー | 自己免疫疾患および炎症性疾患の治療 |
US20020068057A1 (en) | 1994-03-10 | 2002-06-06 | Marc Feldmann | Treatment of autoimmune and inflammatory disorders |
PT840618E (pt) | 1995-05-18 | 2003-08-29 | Ortho Mcneil Pharm Inc | Inducao de tolerancia imunologica atraves de anticorpos anti-cd4 nao-depletores |
BRPI9715219B8 (pt) | 1996-02-09 | 2015-07-07 | Abbvie Biotechnology Ltd | Vetor recombinante de expressão, e célula hospedeira procariótica. |
US20010056066A1 (en) | 1996-07-26 | 2001-12-27 | Smithkline Beecham Corporation | Method of treating immune cell mediated systemic diseases |
EP0946195A1 (en) | 1996-10-01 | 1999-10-06 | Celltech Therapeutics Limited | Pharmaceutical products containing protein-tyrosine kinase inhibitors and anti-cd4 antibodies |
US6037454A (en) | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
DE19722888A1 (de) | 1997-05-28 | 1998-12-03 | Thomas Prof Dr Huenig | Human-CD28 spezifische monoklonale Antikörper zur antigenunspezifischen Aktivierung von T-Lymphozyten |
AU3633000A (en) | 1999-03-26 | 2000-10-16 | Human Genome Sciences, Inc. | Neutrokine-alpha binding proteins and methods based thereon |
DE60042785D1 (de) | 1999-06-09 | 2009-10-01 | Immunomedics Inc | Immuntherapie von autoimmunerkrankungen durch die verwendung von b-zell spezifischen antikörpern |
US7304127B2 (en) | 1999-08-27 | 2007-12-04 | United States Of America As Represented By The Secretary, Department Of Health And Human Services | Polypeptides that bind HIV gp120 and related nucleic acids, antibodies, compositions, and methods of use |
AU6941000A (en) * | 1999-08-27 | 2001-03-26 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | Polypeptides that bind hiv gp120 and related nucleic acids, antibodies, compositions, and methods of use |
AU2001275186A1 (en) | 2000-06-02 | 2001-12-17 | Nicole Kirchhof | Immunotherapeutic method to prevent islet cell rejection |
KR20040023565A (ko) | 2000-09-18 | 2004-03-18 | 아이덱 파마슈티칼즈 코포레이션 | B 세포 고갈/면역조절 항체 조합을 이용한 자가면역질환의 치료를 위한 조합 요법 |
DE10050935A1 (de) | 2000-10-11 | 2002-05-02 | Tegenero Gmbh | Verwendung CD28 spezifischer monoklonaler Antikörper zur Stimulation von Blutzellen, welche kein CD28 tragen |
US6726923B2 (en) | 2001-01-16 | 2004-04-27 | Vascular Therapies, Llc | Apparatus and methods for preventing or treating failure of hemodialysis vascular access and other vascular grafts |
WO2002072759A2 (en) | 2001-03-07 | 2002-09-19 | Children's Medical Center Corporation | Method to screen peptide display libraries using minicell display |
EP1241249A1 (en) | 2001-03-12 | 2002-09-18 | Gerold Schuler | CD4+CD25+regulatory T cells from human blood |
US20040136949A1 (en) | 2001-04-24 | 2004-07-15 | Matthias Grell | Combination therapy using anti-angiogenic agents and tnf alpha |
US7541443B2 (en) | 2001-06-14 | 2009-06-02 | Tolerrx, Inc. | Anti-CD4 antibodies |
GB2376466A (en) | 2001-06-14 | 2002-12-18 | Mark Frewin | TRX1 antibody |
JP4448906B2 (ja) | 2001-06-14 | 2010-04-14 | イシス イノベーション リミテッド | Cd4特異的抗体trx1およびその使用 |
AU2002357427A1 (en) | 2001-12-04 | 2003-06-17 | Tegenero Ag | Peptide or protein containing a c'-d loop of the cd28 receptor family |
DE10212108A1 (de) | 2002-03-13 | 2003-10-02 | Tegenero Ag | Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung |
DE10230223A1 (de) | 2002-07-04 | 2004-01-22 | Tegenero Ag | Mikropartikel mit CD28-spezifischen monoklonalen Antikörpern |
EP2444409A2 (en) | 2002-09-16 | 2012-04-25 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
US7388079B2 (en) | 2002-11-27 | 2008-06-17 | The Regents Of The University Of California | Delivery of pharmaceutical agents via the human insulin receptor |
US7501494B2 (en) | 2003-01-15 | 2009-03-10 | United Biomedical, Inc. | Designed deimmunized monoclonal antibodies for protection against HIV exposure and treatment of HIV infection |
EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
JP2006522811A (ja) | 2003-04-09 | 2006-10-05 | ジェネンテック・インコーポレーテッド | TNFαインヒビターに対して不十分な反応を示す患者の自己免疫疾患治療法 |
GB0314461D0 (en) | 2003-06-20 | 2003-07-23 | Isis Innovation | Suppression of transplant rejection |
AU2003264100A1 (en) | 2003-08-25 | 2005-03-10 | Pieris Proteolab Ag | Muteins of a bilin-binding protein with affinity for a given target |
EP1600164A3 (de) | 2003-09-22 | 2006-05-17 | TeGenero AG | Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer Pharmazeutischen Zusammensetzung mit dosisabhängiger Wirkung |
DE10352900A1 (de) | 2003-11-11 | 2005-06-16 | Tegenero Ag | Verwendung einer an CD28 bindenden Wirksubstanz zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von B-CLL |
JP2008503593A (ja) | 2004-06-22 | 2008-02-07 | トーラーレックス, インク. | 霊長類で寛容を誘導するための抗cd4抗体で最適化された投薬 |
US7410772B2 (en) | 2004-07-02 | 2008-08-12 | Genentech, Inc. | Compositions and methods for treatment of non-Hodgkin's lymphoma |
WO2006035876A1 (ja) | 2004-09-29 | 2006-04-06 | Kowa Co., Ltd. | 関節リウマチの予防及び/又は治療薬 |
PT2171060E (pt) | 2004-11-11 | 2013-11-18 | Theramab Llc | Anticorpo anti-cd28 superagonista |
US8119589B2 (en) | 2004-11-12 | 2012-02-21 | University Of North Carolina At Charlotte | Modulation of CD4+ T cell responses by a tick saliva protein, Salp15 and polypeptides derived therefrom |
DE102004063494A1 (de) | 2004-12-23 | 2006-07-13 | Tegenero Ag | Antikörper |
JP4730733B2 (ja) | 2005-05-02 | 2011-07-20 | 国立大学法人京都大学 | 4型葉酸受容体の発現を指標とした制御性t細胞の検出方法、及び免疫賦活剤 |
SG163615A1 (en) | 2005-07-11 | 2010-08-30 | Macrogenics Inc | Methods for the treatment of autoimmune disorders using immunosuppressive monoclonal antibodies with reduced toxicity |
CN101287493A (zh) | 2005-08-18 | 2008-10-15 | 根马布股份公司 | 采用cd4结合肽和辐射的疗法 |
BRPI0615397B1 (pt) | 2005-08-26 | 2023-10-03 | Roche Glycart Ag | Anticorpo anti-cd20, composição farmacêutica que o contém e uso do mesmo |
ES2526204T3 (es) | 2006-01-05 | 2015-01-08 | Genentech, Inc. | Anticuerpos anti-EphB4 y métodos para usar los mismos |
JP2009530290A (ja) | 2006-03-16 | 2009-08-27 | ジェネンテック・インコーポレーテッド | Cd4抗体を使用するループスの治療方法 |
EP2010569A4 (en) | 2006-03-20 | 2009-09-09 | Xoma Technology Ltd | FOR GASTRIN SPECIFIC HUMAN ANTIBODIES, MATERIALS AND METHODS |
WO2007117602A2 (en) | 2006-04-07 | 2007-10-18 | Biogen Idec Ma Inc. | Isolation and use of human regulatory t cells |
KR101317235B1 (ko) | 2006-04-21 | 2013-10-15 | 조마 테크놀로지 리미티드 | 길항제 항-cd40 항체 제약 조성물 |
WO2007135684A2 (en) * | 2006-05-22 | 2007-11-29 | Hadasit Medical Research Services & Development Limited | Method of treatment of anti-cd4 autoimmunity |
WO2008092905A2 (en) | 2007-02-01 | 2008-08-07 | Boehringer Ingelheim International Gmbh | Specific activation of a regulatory t cell and its use for treatment of asthma, allergic disease, autoimmune disease, graft rejection and for tolerance induction |
TWI570135B (zh) | 2007-04-27 | 2017-02-11 | 建南德克公司 | 高效、穩定且非免疫抑制之抗-cd4抗體 |
SG190627A1 (en) * | 2008-03-13 | 2013-06-28 | Biotest Ag | Agent for treating disease |
MX2010010028A (es) | 2008-03-13 | 2011-08-17 | Biotest Ag | Agente para tratar enfermedad. |
EP2262838B1 (en) * | 2008-03-13 | 2016-04-13 | Biotest AG | Agent for treating disease |
EP2101173A1 (en) | 2008-03-14 | 2009-09-16 | Vivalis | In vitro method to determine whether a drug candidate active against a target protein is active against a variant of said protein |
WO2010022341A1 (en) | 2008-08-21 | 2010-02-25 | The United State Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of enriching and using regulatory t cells |
ES2335381B1 (es) | 2008-09-24 | 2011-02-28 | Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron | Metodo in vitro y kit para el pronostico o prediccion de la respuestapor parte de pacientes con artritis reumatoide al tratamiento con agentes bloqueantes del factor tnfalfa. |
DK2341937T3 (en) | 2008-09-29 | 2015-02-09 | Biotest Ag | Composition for the treatment of a disease |
ES2351456B1 (es) | 2009-06-24 | 2011-11-28 | Fundacio Institut De Recerca De L'hospital Universitari Vall D'hebron | Metodo in vitro para el pronostico o prediccion de la respuesta por parte de pacientes con artritis reumatoide al tratamiento con agentes que reconocen el receptor de membrana cd20 de los linfocitos b |
JP5399219B2 (ja) | 2009-11-24 | 2014-01-29 | 株式会社ケイティーバイオ | 関節リウマチに対するヒト型抗TNFα抗体薬の薬効予測方法、及び薬効予測装置 |
WO2011158798A1 (ja) | 2010-06-14 | 2011-12-22 | 国立大学法人山口大学 | 乾癬治療効果の経過観察及び早期の予測方法並びにそれらに使用するキット |
-
2009
- 2009-11-30 GB GBGB0920944.6A patent/GB0920944D0/en not_active Ceased
-
2010
- 2010-11-30 CA CA2781836A patent/CA2781836A1/en not_active Abandoned
- 2010-11-30 AU AU2010323045A patent/AU2010323045B2/en not_active Ceased
- 2010-11-30 WO PCT/EP2010/068579 patent/WO2011064407A1/en active Application Filing
- 2010-11-30 NZ NZ600889A patent/NZ600889A/en not_active IP Right Cessation
- 2010-11-30 SG SG2012039442A patent/SG181117A1/en unknown
- 2010-11-30 RU RU2012127378/10A patent/RU2598719C2/ru not_active IP Right Cessation
- 2010-11-30 JP JP2012541473A patent/JP5959438B2/ja active Active
- 2010-11-30 CN CN201080059459.9A patent/CN102687010B/zh active Active
- 2010-11-30 KR KR1020127016947A patent/KR101872746B1/ko active IP Right Grant
- 2010-11-30 SG SG10201407938TA patent/SG10201407938TA/en unknown
- 2010-11-30 EP EP10782326.2A patent/EP2470902B1/en active Active
- 2010-11-30 ES ES10782326.2T patent/ES2643640T3/es active Active
- 2010-11-30 BR BR112012012911A patent/BR112012012911A8/pt not_active Application Discontinuation
- 2010-11-30 MX MX2012006199A patent/MX347247B/es active IP Right Grant
-
2012
- 2012-05-23 IL IL219956A patent/IL219956B/en not_active IP Right Cessation
- 2012-05-30 US US13/483,280 patent/US9995733B2/en active Active
- 2012-06-28 ZA ZA2012/04845A patent/ZA201204845B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN102687010A (zh) | 2012-09-19 |
IL219956B (en) | 2019-07-31 |
CN102687010B (zh) | 2016-06-15 |
GB0920944D0 (en) | 2010-01-13 |
BR112012012911A8 (pt) | 2018-02-27 |
KR20120102733A (ko) | 2012-09-18 |
AU2010323045A1 (en) | 2012-07-19 |
AU2010323045B2 (en) | 2015-09-24 |
US20130004513A1 (en) | 2013-01-03 |
MX2012006199A (es) | 2012-06-19 |
KR101872746B1 (ko) | 2018-06-29 |
MX347247B (es) | 2017-04-17 |
EP2470902B1 (en) | 2017-07-19 |
IL219956A0 (en) | 2012-07-31 |
JP5959438B2 (ja) | 2016-08-02 |
BR112012012911A2 (pt) | 2016-10-25 |
WO2011064407A1 (en) | 2011-06-03 |
NZ600889A (en) | 2015-09-25 |
SG181117A1 (en) | 2012-07-30 |
US9995733B2 (en) | 2018-06-12 |
ES2643640T3 (es) | 2017-11-23 |
CA2781836A1 (en) | 2011-06-03 |
ZA201204845B (en) | 2016-06-29 |
RU2012127378A (ru) | 2014-01-10 |
RU2598719C2 (ru) | 2016-09-27 |
JP2013511996A (ja) | 2013-04-11 |
EP2470902A1 (en) | 2012-07-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG10201407938TA (en) | Agents for treating disease | |
MY173839A (en) | Cd37-binding molecules and immunoconjugates thereof | |
EA201390575A1 (ru) | Неантагонистические egfr-связывающие молекулы и их иммуноконъюгаты | |
MX2013004761A (es) | Nuevas moleculas de union al receptor del factor de crecimiento epidermico (egfr) e inmunoconjugados de estas. | |
IN2014CN03042A (es) | ||
GB201020995D0 (en) | Biological materials and uses thereof | |
MX354450B (es) | Anticuerpos anti proteína accesoria del receptor de interleucina-1 y su uso para tratamiento en humanos. | |
MX369220B (es) | Moleculas que enlazan cd3 capaces de enlazar a cd3 humano y no humano. | |
EP2566890A4 (en) | ANTI-PAI-1 ANTIBODIES AND METHOD FOR THEIR USE | |
MX341076B (es) | Formulaciones estables de anticuerpos para el receptor humano pd-1 de meurte programada y tratamientos relacionados. | |
MY161909A (en) | Anti-her3 antibodies and uses thereof | |
CA3019531A1 (en) | Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer | |
AU2012335543A8 (en) | HER3 antibodies and uses thereof | |
MY184251A (en) | Human anti-tau antibodies | |
MY164647A (en) | Cea antibodies | |
NZ709353A (en) | Antibodies that bind il-4 and/or il-13 and their uses | |
MX2014004326A (es) | Anticuerpos a cd1d. | |
MX345092B (es) | Anticuerpos anti-tau humanos,. | |
WO2012019024A3 (en) | Her3-binding molecules and immunoconjugates thereof | |
MY150709A (en) | Human cytomegalovirus neutralising antibodies and use thereof | |
MX2013011385A (es) | Moleculas de union a cd37 y sus inmunoconjugados. | |
WO2013013025A3 (en) | Anti-cxcr4 antibodies and methods of use | |
MX337203B (es) | Novedosas moleculas inhbidoras de jnk. | |
EA201201526A1 (ru) | Способы лечения состояний, связанных с il-1b | |
JO3437B1 (ar) | أجسام مضادة محسنة مضادة للفراكتالكين البشري واستخداماتها |