PT840618E - Inducao de tolerancia imunologica atraves de anticorpos anti-cd4 nao-depletores - Google Patents
Inducao de tolerancia imunologica atraves de anticorpos anti-cd4 nao-depletoresInfo
- Publication number
- PT840618E PT840618E PT96915808T PT96915808T PT840618E PT 840618 E PT840618 E PT 840618E PT 96915808 T PT96915808 T PT 96915808T PT 96915808 T PT96915808 T PT 96915808T PT 840618 E PT840618 E PT 840618E
- Authority
- PT
- Portugal
- Prior art keywords
- immunological tolerance
- depleters
- nao
- antibodies
- induction
- Prior art date
Links
- 230000001900 immune effect Effects 0.000 title abstract 2
- 230000006698 induction Effects 0.000 title 1
- 230000000779 depleting effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 241000288906 Primates Species 0.000 abstract 1
- 210000001185 bone marrow Anatomy 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Transplantation (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44373995A | 1995-05-18 | 1995-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT840618E true PT840618E (pt) | 2003-08-29 |
Family
ID=23762005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96915808T PT840618E (pt) | 1995-05-18 | 1996-05-16 | Inducao de tolerancia imunologica atraves de anticorpos anti-cd4 nao-depletores |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP1161955A3 (pt) |
| JP (1) | JPH11505251A (pt) |
| AT (1) | ATE238066T1 (pt) |
| AU (1) | AU715052B2 (pt) |
| CA (1) | CA2221350A1 (pt) |
| DE (1) | DE69627665T2 (pt) |
| DK (1) | DK0840618T3 (pt) |
| ES (1) | ES2196150T3 (pt) |
| PT (1) | PT840618E (pt) |
| WO (1) | WO1996036359A1 (pt) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998023746A1 (en) * | 1996-11-27 | 1998-06-04 | Genentech, Inc. | Antibody mutants |
| US6037454A (en) * | 1996-11-27 | 2000-03-14 | Genentech, Inc. | Humanized anti-CD11a antibodies |
| EP2345424A1 (en) * | 2001-06-14 | 2011-07-20 | Tolerx, Inc | CD4-specific antibody TRX1 and uses therefor |
| US7541443B2 (en) | 2001-06-14 | 2009-06-02 | Tolerrx, Inc. | Anti-CD4 antibodies |
| EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
| TW200817438A (en) | 2006-08-17 | 2008-04-16 | Hoffmann La Roche | A conjugate of an antibody against CCR5 and an antifusogenic peptide |
| CL2008000707A1 (es) | 2007-03-13 | 2008-09-22 | Hoffmann La Roche | Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion. |
| US20090022720A1 (en) | 2007-07-20 | 2009-01-22 | Stephan Fischer | Conjugate of an antibody against CD4 and antifusogenic peptides |
| WO2009121690A1 (en) | 2008-03-13 | 2009-10-08 | Biotest Ag | Agent for treating disease |
| ES2569217T3 (es) | 2008-03-13 | 2016-05-09 | Biotest Ag | Agente para tratar enfermedades |
| BRPI0909179A2 (pt) | 2008-03-13 | 2015-08-25 | Biotest Ag | Composição farmacêutica, e, método de tratamento de uma doença autoimune. |
| US8637466B2 (en) | 2008-08-11 | 2014-01-28 | Nektar Therapeutics | Multi-arm polymeric alkanoate conjugates |
| GB0920944D0 (en) | 2009-11-30 | 2010-01-13 | Biotest Ag | Agents for treating disease |
| EP2471543A1 (en) | 2010-12-02 | 2012-07-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Tolerance induction or immunosupression to prevent in particular Graft-versus-Host-Disease (GvHD) by short-term pre-incubation of transplanted cell suspensions, tissues or organs coated with ligands to cell surface molecules |
| WO2012088422A1 (en) | 2010-12-22 | 2012-06-28 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of taxane-based compounds |
| US10894087B2 (en) | 2010-12-22 | 2021-01-19 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds |
| US20140088021A1 (en) | 2011-05-27 | 2014-03-27 | Nektar Therapeutics | Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4904481A (en) * | 1985-04-17 | 1990-02-27 | The Board Of Trustess Of Leland Stanford University | Method of conferring immuno-tolerance to a specific antigen |
| GB8608068D0 (en) * | 1986-04-02 | 1986-05-08 | Cobbold S P | Monoclonal antibodies |
| GB8912497D0 (en) * | 1989-05-31 | 1989-07-19 | Cobbold Stephen P | Monoclonal antibodies |
| GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9020282D0 (en) * | 1990-09-17 | 1990-10-31 | Gorman Scott D | Altered antibodies and their preparation |
-
1996
- 1996-05-16 WO PCT/US1996/006912 patent/WO1996036359A1/en active IP Right Grant
- 1996-05-16 PT PT96915808T patent/PT840618E/pt unknown
- 1996-05-16 DK DK96915808T patent/DK0840618T3/da active
- 1996-05-16 CA CA002221350A patent/CA2221350A1/en not_active Abandoned
- 1996-05-16 AT AT96915808T patent/ATE238066T1/de not_active IP Right Cessation
- 1996-05-16 EP EP01202886A patent/EP1161955A3/en not_active Withdrawn
- 1996-05-16 JP JP8534995A patent/JPH11505251A/ja not_active Withdrawn
- 1996-05-16 AU AU57479/96A patent/AU715052B2/en not_active Ceased
- 1996-05-16 EP EP96915808A patent/EP0840618B1/en not_active Expired - Lifetime
- 1996-05-16 ES ES96915808T patent/ES2196150T3/es not_active Expired - Lifetime
- 1996-05-16 DE DE69627665T patent/DE69627665T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2221350A1 (en) | 1996-11-21 |
| EP1161955A2 (en) | 2001-12-12 |
| DE69627665D1 (de) | 2003-05-28 |
| ATE238066T1 (de) | 2003-05-15 |
| AU715052B2 (en) | 2000-01-13 |
| EP1161955A3 (en) | 2001-12-19 |
| EP0840618A1 (en) | 1998-05-13 |
| DE69627665T2 (de) | 2004-02-19 |
| AU5747996A (en) | 1996-11-29 |
| ES2196150T3 (es) | 2003-12-16 |
| EP0840618B1 (en) | 2003-04-23 |
| JPH11505251A (ja) | 1999-05-18 |
| WO1996036359A1 (en) | 1996-11-21 |
| DK0840618T3 (da) | 2003-08-11 |
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