DK0840618T3 - Induktion af immunologisk tolerance ved anvendelse af uudtømmelige anti-CD4-antistoffer - Google Patents

Induktion af immunologisk tolerance ved anvendelse af uudtømmelige anti-CD4-antistoffer

Info

Publication number
DK0840618T3
DK0840618T3 DK96915808T DK96915808T DK0840618T3 DK 0840618 T3 DK0840618 T3 DK 0840618T3 DK 96915808 T DK96915808 T DK 96915808T DK 96915808 T DK96915808 T DK 96915808T DK 0840618 T3 DK0840618 T3 DK 0840618T3
Authority
DK
Denmark
Prior art keywords
immunological tolerance
inexhaustible
antibodies
induction
compositions
Prior art date
Application number
DK96915808T
Other languages
English (en)
Inventor
Robert W Knowles
Druie E Cavender
Judith M Thomas
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK0840618T3 publication Critical patent/DK0840618T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96915808T 1995-05-18 1996-05-16 Induktion af immunologisk tolerance ved anvendelse af uudtømmelige anti-CD4-antistoffer DK0840618T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44373995A 1995-05-18 1995-05-18
PCT/US1996/006912 WO1996036359A1 (en) 1995-05-18 1996-05-16 Induction of immunological tolerance by the use of non-depleting anti-cd4 antibodies

Publications (1)

Publication Number Publication Date
DK0840618T3 true DK0840618T3 (da) 2003-08-11

Family

ID=23762005

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96915808T DK0840618T3 (da) 1995-05-18 1996-05-16 Induktion af immunologisk tolerance ved anvendelse af uudtømmelige anti-CD4-antistoffer

Country Status (10)

Country Link
EP (2) EP0840618B1 (da)
JP (1) JPH11505251A (da)
AT (1) ATE238066T1 (da)
AU (1) AU715052B2 (da)
CA (1) CA2221350A1 (da)
DE (1) DE69627665T2 (da)
DK (1) DK0840618T3 (da)
ES (1) ES2196150T3 (da)
PT (1) PT840618E (da)
WO (1) WO1996036359A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0946727B1 (en) * 1996-11-27 2007-01-24 Genentech, Inc. Antibody mutants
US6037454A (en) 1996-11-27 2000-03-14 Genentech, Inc. Humanized anti-CD11a antibodies
US7541443B2 (en) 2001-06-14 2009-06-02 Tolerrx, Inc. Anti-CD4 antibodies
JP4448906B2 (ja) * 2001-06-14 2010-04-14 イシス イノベーション リミテッド Ｃｄ４特異的抗体ｔｒｘ１およびその使用
EP1460088A1 (en) 2003-03-21 2004-09-22 Biotest AG Humanized anti-CD4 antibody with immunosuppressive properties
TW200817438A (en) 2006-08-17 2008-04-16 Hoffmann La Roche A conjugate of an antibody against CCR5 and an antifusogenic peptide
US20090143288A1 (en) 2007-03-13 2009-06-04 Roche Palo Alto Llc Peptide-complement conjugates
CL2008002092A1 (es) 2007-07-20 2009-05-29 Hoffmann La Roche Conjugado que contiene dos o mas peptidos antifusogenicos y un anticuerpo anti-cd-4; metodo de produccion; composicion farmaceutica que lo comprende; polipeptidos antifusogenicos y uso del conjugado para tratar infecciones viricas.
ES2610327T3 (es) 2008-03-13 2017-04-27 Biotest Ag Régimen de dosificación de anticuerpos anti-CD4 para el tratamiento de enfermedades autoinmunitarias
AU2009231325B2 (en) 2008-03-13 2014-09-18 Biotest Ag Agent for treating disease
BRPI0909180A2 (pt) 2008-03-13 2016-08-09 Biotest Ag composição farmacêutica, e, método de tratamento de uma doença autoimune
MX2011001583A (es) 2008-08-11 2011-04-04 Nektar Therapeutics Conjugados de alcanoato polimericos de multiples brazos.
GB0920944D0 (en) 2009-11-30 2010-01-13 Biotest Ag Agents for treating disease
EP2471543A1 (en) * 2010-12-02 2012-07-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Tolerance induction or immunosupression to prevent in particular Graft-versus-Host-Disease (GvHD) by short-term pre-incubation of transplanted cell suspensions, tissues or organs coated with ligands to cell surface molecules
WO2012088422A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of taxane-based compounds
WO2012088445A1 (en) 2010-12-22 2012-06-28 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20140088021A1 (en) 2011-05-27 2014-03-27 Nektar Therapeutics Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4904481A (en) * 1985-04-17 1990-02-27 The Board Of Trustess Of Leland Stanford University Method of conferring immuno-tolerance to a specific antigen
GB8608068D0 (en) * 1986-04-02 1986-05-08 Cobbold S P Monoclonal antibodies
GB8912497D0 (en) * 1989-05-31 1989-07-19 Cobbold Stephen P Monoclonal antibodies
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
GB9020282D0 (en) * 1990-09-17 1990-10-31 Gorman Scott D Altered antibodies and their preparation

Also Published As

Publication number Publication date
AU5747996A (en) 1996-11-29
ATE238066T1 (de) 2003-05-15
EP0840618A1 (en) 1998-05-13
DE69627665D1 (de) 2003-05-28
JPH11505251A (ja) 1999-05-18
PT840618E (pt) 2003-08-29
CA2221350A1 (en) 1996-11-21
AU715052B2 (en) 2000-01-13
ES2196150T3 (es) 2003-12-16
WO1996036359A1 (en) 1996-11-21
EP0840618B1 (en) 2003-04-23
EP1161955A3 (en) 2001-12-19
EP1161955A2 (en) 2001-12-12
DE69627665T2 (de) 2004-02-19

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