GB9015908D0
(en)
*
|
1990-07-19 |
1990-09-05 |
Celltech Ltd |
Multivalent immunoglobulin
|
JPH06500780A
(en)
*
|
1990-08-31 |
1994-01-27 |
ブリストル―マイアーズ スクイブ カンパニー |
homozygous immunoglobulin
|
GB9112536D0
(en)
*
|
1991-06-11 |
1991-07-31 |
Celltech Ltd |
Chemical compounds
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
EP1817340B1
(en)
|
2004-11-12 |
2012-05-16 |
Xencor, Inc. |
Fc variants with altered binding to fcrn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
CA2624189A1
(en)
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
WO2007044616A2
(en)
|
2005-10-06 |
2007-04-19 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
PL2383297T3
(en)
|
2006-08-14 |
2013-06-28 |
Xencor Inc |
Optimized antibodies that target CD19
|
US8394374B2
(en)
|
2006-09-18 |
2013-03-12 |
Xencor, Inc. |
Optimized antibodies that target HM1.24
|
LT2808343T
(en)
|
2007-12-26 |
2019-09-10 |
Xencor Inc. |
Fc variants with altered binding to FcRn
|
EP2249661B1
(en)
|
2008-01-22 |
2018-05-16 |
Multimerics APS |
Products and methods to prevent infection
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
WO2010112194A1
(en)
|
2009-04-02 |
2010-10-07 |
F. Hoffmann-La Roche Ag |
Antigen-binding polypeptides and multispecific antibodies comprising them
|
WO2010112193A1
(en)
|
2009-04-02 |
2010-10-07 |
Roche Glycart Ag |
Multispecific antibodies comprising full length antibodies and single chain fab fragments
|
WO2010115552A1
(en)
|
2009-04-07 |
2010-10-14 |
Roche Glycart Ag |
Bispecific anti-erbb-3/anti-c-met antibodies
|
AU2010233993A1
(en)
|
2009-04-07 |
2011-09-08 |
Roche Glycart Ag |
Bispecific anti-ErbB-1/anti-c-Met antibodies
|
JP5616428B2
(en)
|
2009-04-07 |
2014-10-29 |
ロシュ グリクアート アクチェンゲゼルシャフト |
Trivalent bispecific antibody
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
AU2010296018B2
(en)
|
2009-09-16 |
2016-05-05 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
WO2011091078A2
(en)
|
2010-01-19 |
2011-07-28 |
Xencor, Inc. |
Antibody fc variants with enhanced complement activity
|
TWI426920B
(en)
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
Bispecific, bivalent anti-vegf/anti-ang-2 antibodies
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
RU2013110875A
(en)
|
2010-08-24 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
SPECIFIC ANTIBODIES CONTAINING DISSULPHIDE-STABILIZED Fv Fragment
|
SG191153A1
(en)
|
2010-12-23 |
2013-07-31 |
Hoffmann La Roche |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
KR20140127854A
(en)
|
2012-02-10 |
2014-11-04 |
제넨테크, 인크. |
Single-chain antibodies and other heteromultimers
|
EA201401077A1
(en)
|
2012-04-05 |
2015-02-27 |
Ф.Хоффманн-Ля Рош Аг |
BISPECIFIC ANTIBODIES TO HUMAN TWEAK AND HUMAN IL17 AND THEIR APPLICATION
|
WO2014001325A1
(en)
|
2012-06-27 |
2014-01-03 |
F. Hoffmann-La Roche Ag |
Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
|
EP2867253B1
(en)
|
2012-06-27 |
2016-09-14 |
F. Hoffmann-La Roche AG |
Method for selection and production of tailor-made highly selective and multi-specific targeting entities containing at least two different binding entities and uses thereof
|
JP6148729B2
(en)
|
2012-07-04 |
2017-06-14 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Covalently bound antigen-antibody conjugate
|
WO2014006123A1
(en)
|
2012-07-04 |
2014-01-09 |
F. Hoffmann-La Roche Ag |
Anti-biotin antibodies and methods of use
|
KR20150023938A
(en)
|
2012-07-04 |
2015-03-05 |
에프. 호프만-라 로슈 아게 |
Anti-theophylline antibodies and methods of use
|
CN104341504B
(en)
|
2013-08-06 |
2017-10-24 |
百奥泰生物科技(广州)有限公司 |
Bispecific antibody
|
WO2015079977A1
(en)
*
|
2013-11-26 |
2015-06-04 |
シャープ株式会社 |
Antibody separation method, antibody evaluation method, medicine evaluation method, and 2-d antibody electrophoresis kit
|
PL3083680T3
(en)
|
2013-12-20 |
2020-06-29 |
F. Hoffmann-La Roche Ag |
Humanized anti-tau(ps422) antibodies and methods of use
|
KR102278429B1
(en)
|
2014-01-03 |
2021-07-16 |
에프. 호프만-라 로슈 아게 |
Covalently linked polypeptide toxin-antibody conjugates
|
JP6476194B2
(en)
|
2014-01-03 |
2019-02-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Bispecific anti-hapten / anti-blood brain barrier receptor antibodies, complexes thereof, and their use as blood brain barrier shuttles
|
MX2016008189A
(en)
|
2014-01-03 |
2016-09-29 |
Hoffmann La Roche |
Covalently linked helicar-anti-helicar antibody conjugates and uses thereof.
|
AR100978A1
(en)
|
2014-06-26 |
2016-11-16 |
Hoffmann La Roche |
ANTI-Tau HUMANIZED ANTIBODY BRAIN LAUNCHERS (pS422) AND USES OF THE SAME
|
ES2764111T3
(en)
|
2014-12-03 |
2020-06-02 |
Hoffmann La Roche |
Multispecific antibodies
|
JP6619460B2
(en)
|
2015-06-24 |
2019-12-11 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Humanized anti-tau (pS422) antibodies and methods of use
|
CN113495141A
(en)
*
|
2020-03-20 |
2021-10-12 |
迈克生物股份有限公司 |
2019 novel coronavirus IgM antibody detection kit
|