WO1991006305A1 - Oligomeric immunoglobulins - Google Patents
Oligomeric immunoglobulins Download PDFInfo
- Publication number
- WO1991006305A1 WO1991006305A1 PCT/US1990/006426 US9006426W WO9106305A1 WO 1991006305 A1 WO1991006305 A1 WO 1991006305A1 US 9006426 W US9006426 W US 9006426W WO 9106305 A1 WO9106305 A1 WO 9106305A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oligomeric
- antibody
- monoclonal antibody
- light chain
- igg
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1275—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Streptococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU70303/91A AU648056B2 (en) | 1989-11-07 | 1990-11-06 | Oligomeric immunoglobulins |
FI913237A FI913237A0 (en) | 1989-11-07 | 1991-07-03 | OLIGOMERIC IMMUNGLOBULINER. |
NO91912640A NO912640L (en) | 1989-11-07 | 1991-07-05 | OLIGOMER IMMUNOGLOBULINES. |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43270089A | 1989-11-07 | 1989-11-07 | |
US432,700 | 1989-11-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1991006305A1 true WO1991006305A1 (en) | 1991-05-16 |
Family
ID=23717254
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1990/006426 WO1991006305A1 (en) | 1989-11-07 | 1990-11-06 | Oligomeric immunoglobulins |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0462246A4 (en) |
JP (1) | JPH04505709A (en) |
AU (1) | AU648056B2 (en) |
CA (1) | CA2045150A1 (en) |
IE (1) | IE904015A1 (en) |
NZ (1) | NZ236000A (en) |
PT (1) | PT95809A (en) |
WO (1) | WO1991006305A1 (en) |
Cited By (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1992001472A1 (en) * | 1990-07-19 | 1992-02-06 | Celltech Limited | Multivalent anti-cytokine immunoglobulins |
WO1992022583A2 (en) * | 1991-06-11 | 1992-12-23 | Celltech Limited | Tri- and tetra-valent monospecific antigen-binding proteins |
EP0547137A1 (en) * | 1990-08-31 | 1993-06-23 | Bristol-Myers Squibb Company | Homoconjugated immunoglobulins |
US7662925B2 (en) | 2002-03-01 | 2010-02-16 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
WO2010040508A1 (en) | 2008-10-08 | 2010-04-15 | F. Hoffmann-La Roche Ag | Bispecific anti-vegf/anti-ang-2 antibodies |
WO2010112194A1 (en) | 2009-04-02 | 2010-10-07 | F. Hoffmann-La Roche Ag | Antigen-binding polypeptides and multispecific antibodies comprising them |
WO2010112193A1 (en) | 2009-04-02 | 2010-10-07 | Roche Glycart Ag | Multispecific antibodies comprising full length antibodies and single chain fab fragments |
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WO2010115552A1 (en) | 2009-04-07 | 2010-10-14 | Roche Glycart Ag | Bispecific anti-erbb-3/anti-c-met antibodies |
WO2010115589A1 (en) | 2009-04-07 | 2010-10-14 | Roche Glycart Ag | Trivalent, bispecific antibodies |
US7973136B2 (en) | 2005-10-06 | 2011-07-05 | Xencor, Inc. | Optimized anti-CD30 antibodies |
WO2011117329A1 (en) | 2010-03-26 | 2011-09-29 | F. Hoffmann-La Roche Ag | Bispecific, bivalent anti-vegf/anti-ang-2 antibodies |
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US8039592B2 (en) | 2002-09-27 | 2011-10-18 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
US8084582B2 (en) | 2003-03-03 | 2011-12-27 | Xencor, Inc. | Optimized anti-CD20 monoclonal antibodies having Fc variants |
US8101720B2 (en) | 2004-10-21 | 2012-01-24 | Xencor, Inc. | Immunoglobulin insertions, deletions and substitutions |
US8124731B2 (en) | 2002-03-01 | 2012-02-28 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
US8188231B2 (en) | 2002-09-27 | 2012-05-29 | Xencor, Inc. | Optimized FC variants |
US8318907B2 (en) | 2004-11-12 | 2012-11-27 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US8388955B2 (en) | 2003-03-03 | 2013-03-05 | Xencor, Inc. | Fc variants |
US8394374B2 (en) | 2006-09-18 | 2013-03-12 | Xencor, Inc. | Optimized antibodies that target HM1.24 |
US8475789B2 (en) | 2008-01-22 | 2013-07-02 | Multimerics Aps | Products and methods to prevent infections |
US8524867B2 (en) | 2006-08-14 | 2013-09-03 | Xencor, Inc. | Optimized antibodies that target CD19 |
US8546543B2 (en) | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
WO2013150043A1 (en) | 2012-04-05 | 2013-10-10 | F. Hoffmann-La Roche Ag | Bispecific antibodies against human tweak and human il17 and uses thereof |
WO2014006124A1 (en) | 2012-07-04 | 2014-01-09 | F. Hoffmann-La Roche Ag | Covalently linked antigen-antibody conjugates |
US8802820B2 (en) | 2004-11-12 | 2014-08-12 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US9040041B2 (en) | 2005-10-03 | 2015-05-26 | Xencor, Inc. | Modified FC molecules |
US9051373B2 (en) | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
WO2015101587A1 (en) | 2014-01-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Covalently linked helicar-anti-helicar antibody conjugates and uses thereof |
WO2015101589A1 (en) | 2014-01-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Covalently linked polypeptide toxin-antibody conjugates |
WO2015101586A1 (en) | 2014-01-03 | 2015-07-09 | F. Hoffmann-La Roche Ag | Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles |
US9200079B2 (en) | 2004-11-12 | 2015-12-01 | Xencor, Inc. | Fc variants with altered binding to FcRn |
US9475881B2 (en) | 2010-01-19 | 2016-10-25 | Xencor, Inc. | Antibody variants with enhanced complement activity |
US9567403B2 (en) | 2013-08-06 | 2017-02-14 | Bio-Thera Solutions, Ltd. | Bispecific antibodies which bind EGFR and VEGF |
US9657106B2 (en) | 2003-03-03 | 2017-05-23 | Xencor, Inc. | Optimized Fc variants |
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JPWO2015079977A1 (en) * | 2013-11-26 | 2017-03-16 | シャープ株式会社 | Antibody separation method, antibody evaluation method, pharmaceutical evaluation method, and antibody two-dimensional electrophoresis kit |
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Also Published As
Publication number | Publication date |
---|---|
EP0462246A4 (en) | 1992-11-25 |
AU648056B2 (en) | 1994-04-14 |
NZ236000A (en) | 1993-09-27 |
PT95809A (en) | 1991-09-13 |
EP0462246A1 (en) | 1991-12-27 |
IE904015A1 (en) | 1991-05-08 |
AU7030391A (en) | 1991-05-31 |
CA2045150A1 (en) | 1991-05-08 |
JPH04505709A (en) | 1992-10-08 |
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